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Effect of temperature on heavy ion-induced single event transient on 16-nm FinFET inverter chains

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chinese Physics B 2023年第4期32卷 504-510页

作者：蔡莉池雅庆叶兵刘郁竹贺泽王海滨孙乾孙瑞琪高帅胡培培闫晓宇李宗臻刘杰 Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China University of chinese Academy of Sciences Beijing 100049China College of Computer Science National University of Defense TechnologyChangsha 410073China College of IoT Engineering Hohai UniversityChangzhou 213022China

The variations of single event transient(SET)pulse width of high-LET heavy ion irradiation in 16-nm-thick bulk silicon fin field-effect transistor(Fin FET)inverter chains with different driven strengths are measured at different ***-dimensional(3D)technology computer-aided design simulations are carried out to study the SET pulse width and saturation current varying with *** and simulation results indicate that the increase in temperature will enhance the parasitic bipolar effect of bulk Fin FET technology,resulting in the increase of SET pulse *** the other hand,the increase of inverter driven strength will change the layout topology,which has a complex influence on the SET temperature effects of Fin FET inverter *** experimental and simulation results show that the device with the strongest driven strength has the least dependence on temperature.

关键词： heavy ion single event effect single event transient Fin FET inverter chain

A versatile synthetic strategy towards rare earth based metal-organic frameworks

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Science china Chemistry 2025年

作者： Quan Shi Yun-Hao Xu Ming-Hui Chen Peng Zhao Wen-Bo Deng Ji Xiong Kai Guo ya-qing Feng Bao Zhang School of Chemical Engineering and Technology Tianjin University Tianjin Collaborative Innovation Center of Chemical Science and Engineering Guangdong Laboratory Chemistry & Fine Chemical Industry Jieyang Center

Rare earth metal-organic frameworks (RE-MOFs) have drawn wide attention owing to diverse network structures and various application ***,due to the unpredictable formation of the nodes,it is still challenging to design novel RE-MOFs.A novel versatile strategy was developed employing a RE-acetate complex (RE2(CH3COO)6·4H2O) as a precursor to construct RE-MOFs.2D RE-MOFs (RE-DBP) and 3D RE-MOFs (RE-TCPP) could be obtained by using dicarboxylic porphyrin ligands H2DBP and tetracarboxylic porphyrin ligands H2TCPP,*** RE-MOFs were further synthesized to verify the universality of the *** crystalline RE-MOFs could also be prepared at room temperature via the developed strategy,which could significantly promote large-scale preparation and practical application of *** proof of the concept,the performance of porphyrin-based RE-MOFs was investigated in the photocatalytic cycloaddition of CO2with *** the RE-DBP(Co) MOFs,Tb-DBP(Co) exhibited the best photocatalytic performance,which was also greater than that of the corresponding 3D MOF Tb-TCPP(Co) due to the optimal 2D structure and thus the accelerated photogenerated charge separation and transfer *** work not only provides a novel versatile strategy to design and develop RE-MOFs,but also proposes a promising approach for the potential bulk production of RE-MOFs at room temperature.

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基于CNN和Transformer交叉教学的半监督医学图像分割

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陕西科技大学学报 2025年第1期43卷 185-192页

作者：杨云胡雯青杨虹吴亚男陕西科技大学电子信息与人工智能学院陕西西安710021 西安富德医疗电子有限公司陕西西安710075 西安计量技术研究院陕西西安710199

由于医学图像分割领域缺乏高质量的标注数据,半监督学习方法在医学图像语义分割任务中受到高度重视.为了充分利用卷积神经网络(Convolutional Neural Network,CNN)和Transformer在半监督学习中的优势,本文提出一种基于CNN与Transformer... 详细信息

由于医学图像分割领域缺乏高质量的标注数据,半监督学习方法在医学图像语义分割任务中受到高度重视.为了充分利用卷积神经网络(Convolutional Neural Network,CNN)和Transformer在半监督学习中的优势,本文提出一种基于CNN与Transformer交叉教学的半监督医学图像分割方法.该方法将经典的深度协同训练从一致性正则化简化为交叉教学,利用循环伪标签方案使两个网络的预测差异转换为无监督损失,以鼓励两个网络具有一致的低熵预测.所提方法在ISIC 2018数据集上进行实验,在采用20%的标注比例时,Dice系数和Jaccard系数分别达到87.25%和79.17%,相比于监督U-Net++的训练结果分别提升了2.89%和3.53%,并且优于目前主流的半监督学习方法,验证了所提方法在半监督医学图像分割上的有效性和泛化性.

关键词：半监督学习图像语义分割交叉教学循环伪标签

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A mathematical model of cortical bone remodeling at cellular level under mechanical stimulus

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Acta Mechanica Sinica 2012年第6期28卷 1678-1692页

作者： qing-Hua Qin ya-Nan Wang Research School of Engineering The Australian National University

A bone cell population dynamics model for cor- tical bone remodeling under mechanical stimulus is devel- oped in this paper. The external experiments extracted from the literature which have not been used in the creation of the model are used to test the validity of the model. Not only can the model compare reasonably well with these ex- perimental results such as the increase percentage of final values of bone mineral content （BMC） and bone fracture en- ergy （BFE） among different loading schemes （which proves the validity of the model）, but also predict the realtime devel- opment pattern of BMC and BFE, as well as the dynamics of osteoblasts （OBA）, osteoclasts （OCA）, nitric oxide （NO） and prostaglandin E2 （PGE2） for each loading scheme, which can hardly be monitored through experiment. In conclusion, the model is the first of its kind that is able to provide an in- sight into the quantitative mechanism of bone remodeling at cellular level by which bone cells are activated by mechan- ical stimulus in order to start resorption/formation of bone mass. More importantly, this model has laid a solid foun- dation based on which future work such as systemic control theory analysis of bone remodeling under mechanical stimu- lus can be investigated. The to-be identified control mecha- nism will help to develop effective drugs and combined non- pharmacological therapies to combat bone loss pathologies. Also this deeper understanding of how mechanical forces quantitatively interact with skeletal tissue is essential for the generation of bone tissue for tissue replacement purposes in tissue engineering.

关键词： Cortical bone remodeling Cell population dy-namics Mechanotransduction Mechanosensitivity Bonefracture energy - Bone mineral content

Mechanism Study on Char Formation of Zinc Acetylacetonate on ABS Resin

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chinese Journal of Polymer Science 2015年第5期33卷 772-782页

作者： ya-qing Ma 庞永艳 Polymers and Composites Division Ningbo Institute of Materials Technology & EngineeringChinese Academy of Sciences

The mechanism of char formation effect of zinc acetylacetonate（Zn（acac）2） on acrylonitrile-butadiene-styrene copolymer（ABS） was studied. Thermal gravimetric analysis（TGA） was used to study the mass loss and char yield of ABS composites. In situ temperature-dependent Fourier transform infrared spectroscopy（FTIR） was used to characterize the chemical change during thermal decomposition. Roman spectroscopy and scanning electron microscopy（SEM） were applied to characterize the structure and morphology of the char after combustion. Results showed that the presence of Zn（acac）2 not only slowed down thermal decomposition of the ABS composites, but also increased the charred residue. A more compact and denser char layer with higher graphitization degree was formed for ABS composites with Zn（acac）2. To study the char formation mechanism of Zn（acac）2 on ABS, thermal decomposition was analyzed for the composites of Zn（acac）2 with PB, PS and SAN, respectively. Also, the chemical structure change was investigated for Zn（acac）2 during thermal decomposition. Based on these results, it was deduced that the increase of char yield of ABS composites was probably attributed to the interaction between the units of acrylonitrile in ABS and zinc acetate, produced during the thermal decomposition of Zn（acac）2. A proposed mechanism for crosslinking and the subsequent char formation was presented.

关键词： Char formation ABS Zinc acetylacetonate Mechanism Decomposition

Effects of phosphate solubilization and phytohormone production of Trichoderma asperellum Q1 on promoting cucumber growth under salt stress

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Journal of Integrative Agriculture 2015年第8期14卷 1588-1597页

作者： ZHAO Lei ZHANG ya-qing College of Life Science Shandong Normal University

Salinity is one of the major abiotic stresses limiting crop growth and *** study investigated the underlying mechanisms of Trichoderma asperellum Q1 in promoting cucumber growth under salt stress, including the abilities of the strain to solubilize phosphate and to produce *** results showed that *** Q1 could solubilize inorganic or organic phosphate and the activities of phosphatases and phytase could be detected in the culture *** hydroponic experiments, the growth of cucumber seedlings was increased in the hydroponic system treated by culture filtrate of strain Q1 with tricalcium phosphate or calcium phytate under salt *** strain also exhibited the ability to produce indole acetic acid（IAA）, gibberellic acid（GA） and abscisic acid（ABA） in liquid medium without any *** levels of those three phytohormones in cucumber seedling leaves also increased after inoculated with this strain, along with increased root growth and root activities of the *** results demonstrated the mechanisms of *** Q1 in alleviating the suppression effect of salt stress involving the change of phytohormone levels in cucumber plant and its ability of phosphate solubilization.

关键词： Trichoderma asperellum Q1 cucumber seedlings phosphate solubilization phytohormone salt stress

Scutellaria baicalensis, the golden herb from the garden of chinese medicinal plants

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Science Bulletin 2016年第18期61卷 1391-1398页

作者： qing Zhao Xiao-ya Chen Cathie Martin Plant Science Research Center Shanghai Chenshan Botanical Garden Shanghai Key Laboratory of Plant Functional Genomics and Resources Shanghai 201602 China Department of Metabolic Biology John Innes CentreNorwich NR4 7UH UK Institute of Plant Physiology and Ecology Shanghai Institutes for Biological Sciences Chinese Academy of SciencesShanghai 200032 China

Scutellaria baicalensis Georgi, or chinese skullcap, has been widely used as a medicinal plant in china for thousands of years, where the preparation from its roots is called Huang-Qin. It has been applied in the treatment of diarrhea, dysentery, hypertension, hemorrhaging, insomnia,inflammation and respiratory infections. Flavones such as baicalin, wogonoside and their aglycones baicalein wogonin are the major bioactive compounds extracted from the root of S. baicalensis. These flavones have been reported to have various pharmacological functions, including anti-cancer,hepatoprotection, antibacterial and antiviral, antioxidant,anticonvulsant and neuroprotective effects. In this review,we focus on clinical applications and the pharmacological properties of the medicinal plant and the flavones extracted from it. We also describe biotechnological and metabolic methods that have been used to elucidate the biosynthetic pathways of the bioactive compounds in Scutellaria.

关键词： Scutellaria baicalensis Flavonoids Anti-cancer Metabolic biology Medicinal plants

Decentralized and Privacy-Preserving Low-Rank Matrix Completion

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Journal of the Operations Research Society of china 2015年第2期3卷 189-205页

作者： An-ya Lin qing Ling Department of Automation University of Science and Technology of ChinaHefeiChina

In this paper,we propose a decentralized algorithm to solve the low-rank matrix completion problem and analyze its privacy-preserving *** that we want to recover a low-rank matrix D=[D1,D2,・・・,DL]from a subset of its *** a network composed of L agents,each agent i observes some entries of *** factorize the unknown matrix D as the product of a public matrix X which is common to all agents and a private matrix Y=[Y1,Y2,・・・,YL]of which Yi is held by agent i *** agent i updates Yi and its local estimate of X,denoted by X(i),in an alternating *** exchanging information with neighbors,all the agents move toward a consensus on the estimates X(i).Once the consensus is(nearly)reached throughout the network,each agent i recovers Di=X(i)Yi,thus D is *** this progress,communication through the network may disclose sensitive information about the data matrices Di to a malicious *** prove that in the proposed algorithm,D-LMaFit,if the network topology is well designed,the malicious agent is unable to reconstruct the sensitive information from others.

关键词： Decentralized algorithm Matrix completion Privacy-preserving

Kangxian ruangan keli inhibits hepatic stellate cell proliferation mediated by PDGF

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World Journal of Gastroenterology 2003年第9期9卷 2050-2053页

作者： Lingyang chi-ZhiZhang qing-JingZhu DepartmentofTraditionalchineseMedicine UnionHospitalq~ongjiMedicalcollegeHuazhongUniversityofScienceandTechnologyWuhan430022HubeiProvinceChina InstituteofLiverDiseases.AffiliatedHospitalofHubeiCollegeofTraditionalchineseMedicine Wuhan430061HubeiProvinceChina

AIM: To investigate the effect of Kangxian ruangan keli (KXR) on hepatic stellate cell (HSC) proliferation mediated by platelet-derived growth factor (PDGF) and the underlying ***: In a serum-free culture system, HSCs were treated with a KXR preparation for 24 hours, followed by stimulation with PDGF-BB for 24 hours. Then the cells were incubated again in the medium containing KXR for 3 hours stimulated with PDGF-BB for 5 minutes, and collected. The proliferation of HSC was examined using an MTT assay and flow cytometry. Tyrosine phosphorylation was detected with Western blotting and visualized by the enhenced chemiluminescent (ECL) ***: The OD values for the HSCs growing in the media without and with addition of PDGF were 0.17±0.06 and0.82±0.05, respectively. The PDGF-induced increase was hindered remarkably by KXR preparation in a dose-dependent manner. The reaction values for the systems with 5mg/mL, 2.5 mg/mL and 1.25 mg/mL of KXR were 0.28±0.03,0.37±0.02 and 0.43±0.04, respectively. Moreover, the percentages of S-phase cells in these KXR-containing culturesystems were 10.95±1.35, 32.76±1.07 and 43.19±1.09,respectively, all of which were significantly lower than that in the culture free of KXR (68.24±2.72). In addition, the values for tyrosine-phosphorylated protein in HSCs treated with 5 mg/mL and 1.25 mg/mL of KXR were 0.1349±0.0072 and 0.1658±0.0025, respectively, which were smaller than that in the cells treated only with PDGF-BB (0.1813±0.0117).CONCLUSION: Within the dose range used in the present study, KXR preparation shows an inhibitory effect on HSC proliferation induced by PDGF. The mechanism of this process may involve interference with tyrosine phosphorylation mediated by PDGF.

关键词：肝星形细胞细胞增殖血小板源性生长因子抗纤软肝颗粒中药制剂