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Special epithelioid trophoblastic tumor:A case report

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World Journal of Clinical Cases 2022年第26期10卷 9354-9360页

作者： ya-Nan Wang yan Dong Lin Wang ya-hui chen Hai-yang Hu Jing Guo Lin Sun Departments of Clinical Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Gynecology Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina Department of Pathology Affiliated Hospital of Jining Medical UniversityJining 272000Shandong ProvinceChina

BACKGROUND Epithelioid trophoblastic tumor(ETT)is a special type of gestational trophoblastic ***,its pathogenesis has been incompletely *** rarely occurs in the ovaries and fallopian tubes,unlike placental site trophoblastic tumor,requiring a histopathological biopsy and immunohistochemistry for further *** SUMMARY A 29-year-old woman with irregular vaginal bleeding and elevated serum chorionic gonadotropin(β-hCG)levels presented similar symptoms to ectopic *** ultrasound revealed abnormal echoes of the left ***,the pathology of the left ovary and fallopian tube was reported as *** patient was followed up with regular hCG measurements and *** blood hCG values showed an upward trend 3 mo after the operation and then chemotherapy was *** current health status is *** For women of childbearing age with elevated serumβ-hCG levels,practitioners should consider ETT and be alert to the poor prognosis of the *** surgery,the patient’s condition should be closely observed to prevent recurrence and *** chemotherapy is only helpful for treating the disease to a certain extent.

关键词： Trophoblastic tumor Epithelioid trophoblastic tumor Serum chorionic gonadotropin Vaginal bleeding The partial hydatidiform mole Choriocarcinoma Case report

Event patterns from negative pion spectra in proton-proton and nucleus-nucleus collisions at SPS

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Chinese Physics C 2018年第10期42卷 103-118页

作者： ya-hui chen Fu-Hu Liu Edward K.Sarkisyan-Grinbaum Institute of Theoretical Physics ＆ State Key Laboratory of Quantum Optics and Quantum Optics Devices Shanxi University TaiyuanShanxi 030006China Experimental Physics Department CERN1211 Geneva 23Switzerland Department of Physics The University of Texas at ArlingtonArlingtonTX 76019USA

Rapidity-dependent transverse momentum spectra of negatively charged pions measured at different rapidities in proton-proton collisions at the Super Proton Synchrotron （SPS） at various energies within its Beam Energy Scan （BES） program are investigated by using one- and two-component standard distributions where the chemical potential and spin property of particles are implemented. The rapidity spectra are described by a double- Gaussian distribution. At the stage of kinetic freeze-out, the event patterns are structured by the scatter plots in the three-dimensional subspaces of velocity, momentum and rapidity. The results of the studies of the rapidityindependent transverse mass spectra measured at mid-rapidity in proton-proton collisions are compared with those based on the similar transverse mass spectra measured in the most central beryllium-beryllium, argon-scandium and lead-lead collisions from the SPS at its BES energies.

关键词： rapidity-dependent transverse momentum spectra fine event patterns three-dimensional space

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The primary controlling parameters of porosity, permeability,and seepage capability of tight gas reservoirs:a case study on Upper Paleozoic Formation in the eastern Ordos Basin,Northern China

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Petroleum Science 2019年第6期16卷 1270-1284页

作者： Hong-Jun Qu Bo yang Xia-He Tian Xin-She Liu Huan yang Wen-Wu Dong ya-hui chen State Key Laboratory of Continental Dynamics Department of GeologyNorthwest UniversityXi’an 710069ShaanxiChina Changqing Oilfi eld Company PetroChinaXi’an 710018ShaanxiChina

Tight sandstone gas(hereafter"tight gas")has become a subject of unconventional gas exploration *** large-scale development and use of tight gas resources in the USA,in particular,facilitated the rapid rebound of natural gas production in the USA,in addition to driving the rapid development of tight gas *** the eastern Ordos Basin,the Upper Paleozoic feature includes multiple layers of gas,a shallow depth,and notable potential for exploration and ***,the reservoirs in the area are relatively tight,exhibit strong heterogeneity,and possess a complex micropore structure,thus restricting the eff ective economic development of oil and ***,research on the primary parameters controlling pore throat structure and the seepage capability of low-permeability reservoirs will be beneficial for the effcient exploration and development of natural gas in the eastern Ordos *** parameters of reservoir porosity and percolation ability,as well as permeability,were analyzed using systematic sampling of the of the Upper Paleozoic Benxi,Taiyuan,and Shanxi Formations in the eastern Ordos Basin,constant-rate mercury injection experiments,nuclear magnetic resonance analysis,and gas–water-phase experimental *** results indicate that reservoir porosity is controlled by the effective pore volume and number,whereas permeability is controlled by the largest throat radius,rather than the *** effective pore volume controls the movable fluid saturation,while reservoir percolation capability is controlled by the effective pore volume,irreducible water saturation,and size of the gas–water two-phase seepage zone.

关键词： Porosity and permeability Largest throat radius Movable fluid saturation Effective pore throat volume The range of gas–water two-phase seepage zone

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Asymmetric Transfer Hydrogenation of Prochiral Ketones in Aqueous Media with New Water-Soluble Chiral Vicinal Diamine as Ligand

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有机化学 2003年第Z1期23卷 63-63页

作者： ZHU Jin MA ya-Ping LIU hui chen Li CUI Xin DENG Jin-Gen Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041 Key Laboratory of Asymmetric Synthesis and Chirotechnology of Sichuan Province and Union Laboratory of Asymmetric Synthesis Chengdu Institute of Organic Chemistry Chinese Academy of Sciences Chengdu 610041

　　As a consequence of the increasing demand for atom economy and environmental friendly methods, the water soluble ligands and their metal complexes are of great interest in catalytic synthesis because of simpler product sepa ration and the possibility of recycling. [1] Unique reactivity and selectivity are often observed in aqueous reactions. [2]Recently, we have developed a new water-soluble chiral vicinal diamine and synthesized its mono-N-tosylated derivative for the first time. The application of its mono-N-tosylated derivative in catalytic asymmetric transfer hydrogenation of prochiral ketones was examined in aqueous media. High activity (up to ＞ 99 % conv. ) and good enatioselectivity ( up to 98% ee ) were achieved for most of prochiral aromatic ketones in organic solvent free system. [3]……

关键词： Aqueous Media Prochiral Ketones transfer hydrogenation environmental friendly solvent free system catalytic synthesis prochiral ketones aromatic ketones metal complexes water soluble aqueous media atom economy

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挂面感官品质质构检测方法初探

粮食与油脂 2016年第10期29卷 67-69页

作者：陆娅陈慧彭文怡上海良友(集团)有限公司技术中心上海200333

采用质构仪对挂面进行检测,得到了硬度、咀嚼性、黏性等数据。将质构仪检测数据和人工对挂面的感官指标(适口性、韧性、光滑性和黏性)进行对比,建立了挂面感官品质质构检测的方法。

关键词：质构检测硬度咀嚼性黏性

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RASSF1A与CyclinD1在胃黏膜病变组织中表达及二者的关系

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世界华人消化杂志 2008年第23期16卷 2604-2609页

作者：陈雅慧兰忠平惠起源李宝莉杨彦玲延安大学医学院病理教研室陕西省延安市716000 延安大学附属医院外科陕西省延安市716000

目的:研究RASSF1A蛋白和CyclinD1在胃癌及癌前病变组织中的表达及二者的关系.方法:收集延安大学附属医院2005-01/2006-10行手术切除的69例胃癌患者临床病理资料和切除标本的组织蜡块.同时收集慢性浅表性胃炎45例、慢性萎缩性胃炎45例、... 详细信息

目的:研究RASSF1A蛋白和CyclinD1在胃癌及癌前病变组织中的表达及二者的关系.方法:收集延安大学附属医院2005-01/2006-10行手术切除的69例胃癌患者临床病理资料和切除标本的组织蜡块.同时收集慢性浅表性胃炎45例、慢性萎缩性胃炎45例、慢性胃炎伴肠化生45例及慢性胃炎伴不典型增生57例胃黏膜组织蜡块.采用免疫组化SP法检测胃癌及癌前病变胃黏膜组织中RASSF1A蛋白和CyclinD1的表达.结果:胃癌组织中RASSF1A表达的阳性率低于其在慢性浅表性胃炎胃黏膜组织中的阳性表达率(χ2=10.4,P<0.05);RASSF1A蛋白的在胃癌癌前病变黏膜中阳性率表达逐渐降低(χ2=28.7,P<0.05),并且与胃癌组织分化程度有关(P<0.05).胃癌组织中CyclinD1表达的阳性率为84.1%,慢性浅表性胃炎黏膜组织中的几乎不表达;CyclinD1在胃癌癌前病变黏膜中阳性率表达逐渐升高(χ2=11.9,P<0.05);胃癌组与其他各组之间阳性率比较均存在显著性差异(χ2=22.0,19.6,29.4,P<0.01);RASSF1A蛋白和CyclinD1蛋白在胃癌中阳性表达率二者呈负相关(rs=-0.323,P<0.05).结论:胃黏膜在从慢性浅表性胃炎→慢性萎缩性胃炎→肠化生→不典型增生→胃癌这一演化模式过程中,RASSF1A蛋白表达减弱,CyclinD1蛋白表达增强;二者的联合检测,对研究胃癌发生发展机制有一定科学意义.

关键词： Ras相关区域家族1A 细胞周期素D1 胃癌免疫组化

Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan chen Xiu-Qing Qiao Guo hui Bojing Sun Dongfang Hou Meidi Wang Xueqian Wu Tao Wu Dong-Sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Heterojunctions LSPR Photocatalyst Phase junction Schottky junction Photothermal effect

Vector meson's spin alignments in high energy reactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 5-20页

作者： Jin-hui chen Zuo-Tang Liang Yu-Gang Ma Xin-Li Sheng Qun Wang Key Laboratory of Nuclear Physics and Ion-beam Application (MoE) Institute of Modern PhysicsFudan University Institute of Frontier and Interdisciplinary Science Key Laboratory of Particle Physics and Particle Irradiation (MOE)Shandong University INFN-Firenze Department of Modern Physics University of Science and Technology of China School of Mechanics and Physics Anhui University of Science and Technology

The global spin alignment of vector mesons has been observed by the STAR collaboration at the Relativistic Heavy Ion Collider （RHIC） at Brookhaven National Laboratory （BNL）.It provides a unique opportunity to probe the correlation between the polarized quark and antiquark in the strongly coupled quark-gluon plasma （sQGP） produced in relativistic heavy ion collisions,opening a new window to explore the properties of s *** addition,spin alignments of vector mesons have also been observed in other high-energy particle collisions such as e+e-annihilations at high energies where hadron production is dominated by quark fragmentation *** results obtained are quite different from those obtained in heavy ion collisions where quark coalescence/combination mechanism dominates suggesting strong dependence on hadronization *** comprehensive studies in different hadronization processes are *** this article,we present a brief review of theoretical and experimental advances in the study of vector meson’s spin alignments in a variety of high-energy particle collisions,with emphasis on hadronization mechanisms.

关键词： vector meson spin alignment global polarization relativistic heavy ion collisions fragmentation

Identification of a dual functional betulinic acid analog for the treatment of osteoarthritis by phenotypic screening

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Science China Life Sciences 2025年第1期 300-302页

作者： Ze-Min Lin Mai Xiang Wen-hui Wei Shu-hui Fan Li chen Jie Wang Xiao-Qian yang Chun-Hao yang Shi-Jun He Jian-Ping Zuo Laboratory of Immunopharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of Sciences School of Pharmacy University of Chinese Academy of Sciences School of Pharmacy Nanjing University of Chinese Medicine State Key Laboratory of Drug Research Department of Medicinal ChemistryShanghai Institute of Materia MedicaChinese Academy of Sciences Innovation Research Institute of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Experiment Center for Science and Technology Shanghai University of Traditional Chinese Medicine

Dear Editor, Phenotypic drug discovery, which observes compound effects on physiology,has given way to targeting specific molecules, but has revived by using modern methods to find drugs based on therapeutic outcomes in disease models(Vincent et al., 2022). Osteoarthritis(OA) is a prevalent chronic joint disorder, primarily affecting knee joints, with osteoclast activation due to low-grade inflammation resulting in increased bone resorption and structural changes in the joint(Katz et al.,2021).

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