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Effects of Multi-Stage Continuous Drought on Photosynthetic Characteristics, Yield and Water Use Efficiency of Winter Wheat

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Phyton-International Journal of Experimental Botany 2020年第3期89卷 691-703页

作者： Daoxi Li Ruitao Lou yanbin Li Zepeng Bian ya’nan Zhu School of Water Conservancy North China University of Water Resources and Electric PowerZhengzhou450000China Changshu River Management Office Changshu215500China

A drought event can cause entire crops to fail or yield *** order to study the effects of continuous drought on photosynthetic characteristics,yield,and water use efficiency(WUE)of winter wheat(Triticum aestivum L.),the winter wheat variety“Aikang 58”was selected as test material with controlling the water of the pot-planted winter wheat under a mobile rainout *** on foot planting and safe wintering,winter wheat was evaluated under different drought conditions,including light,moderate and severe drought at the jointing(B),heading(C),and filling(G)*** soil water content was controlled in a range of 60%to 70%,50%to 60%,and 40%to 50%of the field capacity,*** the experiment,there were 9 single-stage droughts,3 three-stage droughts,and 1 test control(totaling 13 trials).The results are as follows:Under a single-stage drought,the change of net photosynthetic rate(Pn)and stomatal conductance(Gs)have similar trends,and they both decrease significantly with the severity of the *** three-stage continuous droughts,the change curve of Gs shows a constant downward trend;the change curve of Pn showed a“valley shape,”and the minimum value of Pn appeared at the heading *** droughts will reduce the yield of winter *** the three-stage continuous drought conditions,except for light drought,moderate drought and severe drought will cause significant yield reduction,mainly due to lack of water at the jointing and heading *** drought will reduce the WUE,and the difference will reach a significant level under moderate and severe *** present results suggested that when water resources are scarce,it is a better irrigation model to save water and achieve high grain yield by applying appropriate water stress(60%–70%FC)during the critical growth period of winter wheat.

关键词： Continuous drought net photosynthetic rate stomatal conductance Triticum aestivum L water use efficiency grain yield

Voltage-controlled Kerr response in Ni/Pb(Zr_(0.52)Ti_(0.48))O_3 heterostructures

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Chinese Science Bulletin 2014年第36期59卷 5218-5222页

作者： ya Gao Zheng Li Li Shu Jing Ma Cewen nan School of Materials Science and Engineering State Key Lab of New Ceramics and Fine Processing Tsinghua University

Voltage-modified magneto-optical Kerr effect(MOKE) is widely used to describe the converse magnetoelectric(ME) effect in the ferroelectric/ferromagnetic(FE/FM) heterostructures. However, the applied voltage can possibly give rise to electro-optical effect of the FE layer, which would also affect the Kerr signals in the MOKE system. Here, we used an AC voltage to modulate the magnetization in the Ni/Pb(Zr0.52Ti0.48)O3(PZT) heterostructures with different pre-polarization states of the PZT layers to investigate the complexity of the Kerr signals. The results suggested that the voltage control of Kerr signal contained several origins; however, the straininduced ME effect dominated in the ME effect in the heterostructures.

关键词：异质结构电压控制 O3 磁光克尔效应电压调节铅镍二氧化锆

Volatile profile analysis and quality prediction of Longjing tea(Camellia sinensis) by HS-SPME/GC-MS

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012年第12期13卷 972-980页

作者： Jie LIN Yi DAI ya-nan GUO Hai-rong XU Xiao-chang WANG Institute of Tea Science Zhejiang UniversityHangzhou 310058China College of Environmental and Resource Sciences Zhejiang UniversityHangzhou 310058China

This study aimed to analyze the volatile chemical profile of Longjing tea, and further develop a prediction model for aroma quality of Longjing tea based on potent odorants. A total of 21 Longjing samples were analyzed by headspace solid phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS).Pearson's linear correlation analysis and partial least square (PLS) regression were applied to investigate the relationship between sensory aroma scores and the volatile compounds. Results showed that 60 volatile compound scould be commonly detected in this famous green tea. Terpenes and esters were two major groups characterized,representing 33.89% and 15.53% of the total peak area respectively. Ten compounds were determined to contribute significantly to the perceived aroma quality of Longjing tea, especially linalool (0.701), nonanal (0.738), (Z)-3-hexenyl hexanoate (-0.785), and β-ionone (-0.763). On the basis of these 10 compounds, a model (correlation coefficient of89.4% and cross-validated correlation coefficient of 80.4%) was constructed to predict the aroma quality of Longjingtea. Summarily, this study has provided a novel option for quality prediction of green tea based on HS-SPME/GC-MStechnique.

关键词： Partial least square (PLS) regression Green tea Headspace solid phase microextraction (HS-SPME) Volatile profile Quality prediction

β-Cyclodextrin Enhanced Fluorimetric Method for Determination of Amoxicillin in Dosage

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Chemical Research in Chinese Universities 2011年第2期27卷 190-192页

作者： TANG Hui-nan GENG Wei-dong LIU Mou-sheng yaNG ya-ling Faculty of Life Science and Technology Kunming University of Science and Technology Kunming 650224 P. R. China Kunming Productivity Promotion Center Kunming 650021 P R. China

A simple sensitive spectrofluorimetric method was developed for the determination of amoxicillin. Amoxicillin in the presence of formaldehyde produces a fluorescent pyrazine derivative, whose fluorescence intensity can be enhanced by forming an inclusion complex with β-cyclodextrin. Optimum conditions for the determination of amoxicillin were also investigated. Fluorimetric detection was carried out at λex=365 nm and λem=445 nm. The linear range of this method for the determination of amoxicillin is 0.1―10 mg/L and the limit of detection is 0.03 mg/L （IF=102.16ρ-9.6, r=0.9994）. The developed method is practical and can be successfully applied to determine the content of amoxicillin in capsules and tablets with satisfactory results.

关键词： Fluorescence Amoxicillin β-Cyclodextrin Inclusion complex

Age Structure and Growth Pattern of an Endangered Species, Amentotaxus formosana Li

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Journal of Integrative Plant Biology 2007年第2期49卷 157-167页

作者： Chinsu Lin Ming-Hsun Chan Feng-Sheng Chen ya-nan Wang Department of Forestry and Natural Resources National Chiayi University Chiayi 60004 Taiwan China Experimental Forest of College of Bio-Resources and Agriculture National Taiwan University Nan-Tou Hsien 55743 Taiwan China

Amentotaxua formoaana Li is a native, tolerant, and under-wood species in Taiwan. This particular species is only distributed around the Chachayalaishan and Dawushan areas. Because of its rarity, and the endangered and native properties of the species, we explored the regeneration process of the species in the native environment. This paper, therefore, aims to outline the age distribution and growth characteristics of A. formosana in the native stand using the techniques of tree ring analysis. An inventory was conducted in a site at the Chachayalaishan area from 2004 to 2006. According to the inventory, there are 67 trees in the sampling plot among which 16 individual A. formosana trees were counted. This is roughly 24% of the total population. This particular species is distributed around the understory space, while other species such as Litsea spp., Meliosma squamulata Hance, Schefflera octophylla Harms, Elaeocarpus japonicus Sieb et Zucc and Cleyera japonica Thunb are the major species whose canopy occupying the upperstory space of the stand. Results of tree-ring analysis suggest that the age of most of the trees in the sampling plot is between 31 and 90 years old with an average of 56. For the endangered species, A. formosana, age of the Individuals varied from 14 and 126 years old and the average was 58 years old. Age distribution of the species was modeled using the Weibull probability density function and was statistically assessed using Sigmaplot statistical software. The estimate of shape parameter is 1.404 5 indicating a medium regeneration situation. The diameter growth rate of A. formosana is 0.32 cm and ranks 20th among the 26 species in the sampling plot. Using the age as a regressor variable, we can predict the diameter increment of A. formosana efficiently. The coefficient of determination, R^2, is 0.832 2. The diameter growth among the trees of the upperstory and understory was competitive. Relationship between the growth change percentage of A. for

关键词： age structure Amentotaxus formosana growth pattern Weibull function.

Simultaneous determination of 20 food additives by high performance liquid chromatography with photo-diode array detector

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Chinese Chemical Letters 2012年第4期23卷 492-495页

作者： Kang Ma ya nan yang Xiao Xiong Jiang Min Zhao Ye Qiang Cai Division of Chemical Metrology and Analytical Science National Institute of Metrology of ChinaBeijing 100013China Division of Chemical Metrology Jiangsu Institute of MetrologyNanjing 210007China State Ke.v lztbotzltory of Bioactive Substances and Functions of Natural Medicines lnstitute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China

An efficient and accurate analytical method was developed for the simultaneous determination of 20 synthetic food additives, including three sweeteners,seven food colorants,nine synthetic preservatives and caffeine,by high performance liquid chromatography （HPLC） with photodiode array detector（PDA）.This method permits the detection of food additives at very low concentrations（0.005-0.150μg/mL）.The applicability was verified by the determination of food additives present in various foodstuffs.

关键词： Food additives Liquid chromatography Photodiode array detector Drinks

Met-Controlled Allosteric Module of Neural Generation as A New Therapeutic Target in Rodent Brain Ischemia

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Chinese Journal of Integrative Medicine 2021年第12期27卷 896-904页

作者： LI Kang-ning ZHANG Ying-ying YU ya-nan WU Hong-li WANG Zhong Department of Traditional Chinese Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijing(100070)China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing(100700)China

Objective To investigate a Met-controlled allosteric module(AM)of neural generation as a potential therapeutic target for brain *** We selected Markov clustering algorithm(MCL)to mine functional modules in the related target *** to the topological similarity,one functional module was predicted in the modules of baicalin(BA),jasminoidin(JA),cholic acid(CA),compared with I/R model *** functional module included three genes:Inppl1,Met and Dapk3(IMD).By gene ontology enrichment analysis,biological process related to this functional module was *** functional module participated in generation of *** blotting was applied to present the compound-dependent regulation of ***-immunoprecipitation was used to reveal the relationship among the three *** used IF to determine the number of newborn neurons between compound treatment group and ischemia/reperfusion *** expressions of vascular endothelial growth factor(VEGF)and matrix metalloproteinase 9(MMP-9)were supposed to show the changing circumstances for neural generation under cerebral *** Significant reduction in infarction volume and pathological changes were shown in the compound treatment groups compared with the I/R model group(P<0.05).Three nodes in one novel module of IMD were found to exert diverse compound-dependent ischemic-specific excitatory regulatory *** anti-ischemic excitatory allosteric module(AME)of generation of neurons(AME-GN)was validated successfully in *** neurons increased in BJC treatment group(P<0.05).The expression of VEGF and MMP-9 decreased in the compound treatment groups compared with the I/R model group(P<0.05).Conclusions AME demonstrates effectiveness of our pioneering approach to the discovery of therapeutic *** novel approach for AM discovery in an effort to identify therapeutic targets holds the promise of accelerating elucidation of underlying pharmacological mechanisms in cere

关键词： allosteric module InppM-Met-Dapk3 generation of neurons brain ischemia

Advances in synthetic biology-based drug delivery systems for disease treatment

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Chinese Chemical Letters 2024年第11期35卷 66-73页

作者： Yujie Li ya-nan Wang Yin-Gen Luo Hongcai yang Jinrui Ren Xiao Li Department of Interventional Therapy National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China Department of Radiology the Affiliated Cancer Hospital of Zhengzhou UniversityZhengzhou 450003China

With the increasing demand for personalized and precise treatment,the rapid advancement of synthetic biology technology has inevitably led to the development of nanobiology-based drug delivery *** biology-based drug delivery systems are being increasingly used in the treatment of various *** one hand,synthetic biology technology enables the clever combination of chassis cells,bacteria,and their derivatives with nanomaterials,forming nano-artificial hybrid *** systems effectively integrate the functions of both materials,leading to further breakthroughs and optimization of biological *** the other hand,synthetic biology strategies guide the self-assembly of modular nanocomponents with biocatalytic or intelligent response functions,resulting in the mimicry of living cell features such as compartmentalization of enzymatic reactions and responsiveness to external *** provides novel design ideas for the construction of artificial *** paper aims to explore the construction and application of biogenic drug delivery systems based on whole cells,cell membrane-encapsulated nanoparticles,exosomes,bacteria,bacterial outer membrane vesicles and artificial cells,taking into account recent advances in this *** advantages and limitations of current synthetic biology-based nanodrug delivery systems for clinical translation are discussed,and the future prospects of nanotechnology for intelligent drug diagnostic and therapeutic systems are envisioned.

关键词： Drug delivery system Synthetic biology nanotechnology Genetic engineering nanoparticles

Differences in Contents and Formation Methods of Clinical Questions in Chinese and Korean Clinical Practice Guidelines of Acupuncture-Moxibustion:Scoping Review

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Chinese Journal of Integrative Medicine 2023年第12期29卷 1133-1141页

作者： ZHAO nan-qi LIU ya-li DING nan YUAN Jing-yun MOU Dong-xiao DONG Guo-feng WANG Xin WU Xiao-dong Institute of Acupuncture-Moxibustion China Academy of Chinese Medical SciencesBeijing(100700)China Center for Clinical Epidemiology and Evidence-based Medicine Beijing Children's HospitalCapital Medical UniversityBeijing(100045)China College of Acupuncture and Massage Beijing University of Chinese MedicineBeijing(100029)China

Objective:To analyze the differences in the needs of users and the value orientation of clinical practice guidelines(CPGs)by comparing the contents and formation methods of clinical questions in Chinese and Korean CPGs of acupuncture-moxibustion(Acup-Mox).Methods:The full text of CPGs was systematically searched from the official websites of Chinese and Korean traditional medicine societies and Acup-Mox associations,with the topic"Acup-Mox for treating diseases"and the retrieval time up to September 28,*** researchers screened the CPGs independently,and extracted the guidelines'topics,content,quantity and formation methods of clinical *** quantitative data were collected by counting the frequency,and the qualitative data were classified and described by thematic ***:A total of 29 guidelines were included in this study,including 20 Chinese guidelines(305 questions)and 9 Korean guidelines(223 questions).The differences lie in the aspects of content and diversity,and formation *** for content and diversity,Chinese guidelines focused mainly on the questions related to treatment such as the operation of specific intervention(86,28.2%),efficacy of intervention(78,25.6%),and also involving questions in diagnosis,prevention,and *** the clinical questions in Korean guidelines were concentrated to efficacy of intervention(218,97.8%).As for formation method,in Chinese guidelines,questions were usually collected directly from clinicians,and then determined and optimized by *** Korean guidelines,frequently used clinical Acup-Mox interventions would be screened *** the expert group would set up corresponding intervention control measures so as to form clinical questions related to treatment ***:The differences reflect the different needs of clinical practitioners,and the different aims or concepts in developing Acup-Mox guidelines between China and South *** guidelines emphasized promoting oper

关键词： association of acupuncture-moxibustion clinical practice guidelines clinical questions optimize