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effects of neoadjuvant chemotherapy vs chemoradiotherapy in the treatment of esophageal adenocarcinoma:A systematic review and meta-analysis

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World Journal of Gastroenterology 2024年第11期30卷 1621-1635页

作者： Armand Csontos Alíz Fazekas Lajos Szakó Nelli Farkas Csenge papp Szilárd Ferenczi Szabolcs Bellyei péter hegyi András papp department of Surgery University of PécsMedical SchoolClinical CenterPécs H-7624BaranyaHungary Institute of Bioanalysis University of PécsMedical SchoolPécs H-7624BaranyaHungary Institute for Translational Medicine University of PécsMedical SchoolPécs H-7624BaranyaHungary department of emergency Medicine Clinical CenterUniversity of PécsMedical SchoolPécs 7624BaranyaHungary department of Oncotherapy University of PécsMedical SchoolClinical CenterPécs H-7624BaranyaHungary Centre for Translational Medicine Semmelweis UniversityBudapest 1085Hungary Institute of pancreatic diseases Semmelweis UniversityBudapest H-1083Hungary

BACKGROUNd Neoadjuvant therapy is an essential modality for reducing the clinical stage of esophageal cancer;however,the superiority of neoadjuvant chemotherapy(nCT)or neoadjuvant chemoradiotherapy(nCRT)is ***,a discussion of these two modalities is *** To investigate the benefits and complications of neoadjuvant *** To address this concern,predefined criteria were established using the pICO *** independent authors performed comprehensive searches using predetermined *** analyses were performed to identify significant differences between *** publication bias was visualized using funnel *** quality of the data was evaluated using the Risk of Bias Tool 2(RoB2)and the GRAde *** Ten articles,including 1928 patients,were included for the *** difference was detected in pathological complete response(pCR)[pdds ratio(OR):0.27;95%CI:0.16-0.46],30-d mortality(p=0.015;OR:0.4;95%CI:0.22-0.71)favoring the nCRT,and renal failure(p=0.039;OR:1.04;95%CI:0.66-1.64)favoring the *** significant differences were observed in terms of survival,local or distal recurrence,or other clinical or surgical *** result of RoB2 was moderate,and that of the GRAde approach was low or very low in almost all *** Although nCRT may have a higher pCR rate,it does not translate to greater long-term ***,nCRT is associated with higher 30-d mortality,although the specific cause for postoperative complications could not be *** the case of nCT,toxic side effects are suspected,which can reduce the quality of *** the quality of available studies,further randomized trials are required.

关键词： Neoadjuvant Chemotherapy Chemoradiotherapy esophageal cancer Adenocarcinoma

Geometric properties of the first singlet S-wave excited state of two-electron atoms near the critical nuclear charge

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Chinese physics B 2024年第10期33卷 213-219页

作者： Tong Chen Sanjiang yang Wanping zhou Xuesong Mei d haoxue Qiao School of physics and Technology Wuhan UniversityWuhan 430072China College of physics and electronic Science Hubei Normal UniversityHuangshi 435002China School of physics and Telecommunications Huanggang Normal UniversityHuanggang 438000China Wuhan Maritime Communication Research Institute Wuhan 430072China

The geometric structure parameters and radial density distribution of 1s2s1S excited state of the two-electron atomic system near the critical nuclear charge z_(c)were calculated in detail under tripled hylleraas basis *** to the localized behavior observed in the ground and the doubly excited 2p^(23)pe states,for this state our results identify that while the behavior of the inner electron increasingly resembles that of a hydrogen-like atomic system,the outer electron in the excited state exhibits diffused hydrogen-like character and becomes perpendicular to the inner electron as nuclear charge z approaches z_(c).This study provides insights into the electronic structure and stability of the two-electron system in the vicinity of the critical nuclear charge.

关键词： critical nuclear charge two-electron atomic system geometric structure density distribution

Achieving superior mechanical properties of selective laser melted AlSi10Mg via direct aging treatment

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Journal of Materials Science & Technology 2022年第13期108卷 226-235页

作者： h.zhang y.Wang J.J.Wang d.R.Ni d.Wang B.L.Xiao z.y.Ma Shi-changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China College of Materials Science and engineering Shenyang Aerospace University37 Daoyi South AvenueShenyang 110136China

For additive manufactured aluminum alloys,the inferior mechanical properties along the building direction have been a serious *** this study,an optimized heat treatment was developed as a simple and effective *** effects of direct aging on microstructure and mechanical properties along the building direction of AlSi10Mg samples produced via selective laser melting(SLM)were *** results showed that,compared with the conventional heat treatment at elevated temperatures,direct aging at temperatures of 130-190℃ could retain the fine grain microstructure of SLM samples and promote further precipitation of Si phase,however,the growth of pores occurred during direct *** increasing aging temperature,while finer cell structures were obtained,more and larger pores were developed,resulting in decreased density of the *** types of pore formation mechanisms were *** the balance between the refinement of cell structure and the growth of pores,aging at 130℃ was determined as the optimized heat treatment for SLM AlSi10Mg *** tensile strength along the building direction of the 130℃ aged sample was increased from 403 Mpa to 451 Mpa,with relatively high elongation of 6.5%.

关键词： Additive manufacturing Selective laser melting AlSi10Mg alloy,heat treatment

Microstructure and Strain hardening of a Friction Stir Welded high-Strength Al–zn–Mg Alloy

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Acta Metallurgica Sinica(english Letters) 2014年第4期27卷 723-729页

作者： A.h.Feng d.L.Chen z.y.Ma W.y.Ma R.J.Song School of Materials Science and engineering Tongji University State Key Laboratory of Advanced Welding production Technology School of Materials Science and EngineeringHarbin Institute of Technology department of Mechanical and Industrial engineering Ryerson UniversityTorontoON M5B 2K3Canada Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of Sciences

Microstructural evolution and strain hardening behavior of a friction stir welded（FSWed） high-strength7075Al-T651 alloy were *** nugget zone was observed to consist of fine and equiaxed recrystallized grains with a low dislocation density and free of original precipitates,but containing uniformly distributed *** strength,joint efficiency,and ductility of the FSWed joints increased with increasing welding speed.A joint efficiency of ＊91% was achieved at a welding speed of 400 mm/min and rotational rate of 800 r/min,while the ductility remained basically the same as that of the base *** was no obvious strain rate sensitivity observed in both base metal and welded *** both the base metal and FSWed joints exhibited stage III and IV hardening characteristics,the hardening capacity,strain hardening exponent,and strain hardening rate all increased after friction stir welding.

关键词： Aluminum alloy Friction stir welding Mechanical properties Strain hardening

energy exchange between charged relativistic fluids in f(T) gravity

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Communications in Theoretical physics 2024年第10期76卷 108-120页

作者： z yousaf U A Khokhar Nasser Bin Turki T Suzuki department of Mathematics University of the Punjab Quaid-i-Azam Campus department of Mathematics College of Science King Saud University department of Regional Management Faculty of Management Fukushima College

This study focuses on the effects of a polytropic fluid on a charged gravitational source within f(T) gravity, where T is the torsion scalar. We investigate how the electromagnetic field affects the flow of energy in spherically symmetric and static celestial objects that contain relativistic fluids. By using the gravitational decoupling technique, we analyze the effects of polytropic fluid on the dynamics of the gravitational source, accompanied by the matching of the interior geometry with an exterior at the hypersurface Σ. Finally, with the help of the Tolman ⅡV solution, we observe the conduct of energy conditions with the existence of charge using f(T)field equations and got the intended outcomes.

关键词： anisotropy complexity energy exchange hydrodynamics self-gravitating systems

esophageal inserted subclavian catheter:a rare complication

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World Journal of emergency Medicine 2024年第3期15卷 243-245页

作者： dilberÜçöz Kocaşaban SertaçGüler emergency Medicine Clinic Health Sciences University Ankara Training and Research HospitalAnkara 06930Turkey

Central venous catheterization(CVC) is an invasive procedure for administering fluids,nutrients,and drugs;monitoring central venous pressure;performing pulmonary artery catheterization;and placing transvenous pacemakers in intensive care units and all specialties,from anesthesia to emergency medicine,for the treatment of trauma and hemodynamically unstable pediatric and adult patients.[1,2]Complications have been observed in more than 15% of patients who underwent ***,infectious,and thrombotic complications have been reported in 5%–19%,5%–26%,and 2%–26% of patients,respectively.[3] Malposition,on the other hand,is common in subclavian catheter insertion and is usually associated with an initially misplaced guidewire.[4]

关键词： unstable insertion initially

effect of heat-input on pitting corrosion behavior of friction stir welded high nitrogen stainless steel

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Journal of Materials Science & Technology 2019年第7期35卷 1278-1283页

作者： h.zhang p.Xue d.Wang L.h.Wu d.R.Ni B.L.Xiao z.y.Ma Shenyang National Laboratory for Materials Science Institute of Metal Research Chinese Academy of Sciences

In this study, different welding param eters were selected to investigate the effects of heat-in put on the microstructure and corrosion resistance of the friction stir welded high nitrogen stainless steel joints. The results show ed that, the welding speed had major influence on the duration at elevated tem perature rather than the peak tem perature. The hardness distribution and tensile properties of the nugget zones (Nzs) for various joints were very similar while the pitting corrosion behavior of various Nzs showed major differences. Large heat-input resulted in the ferrite bands being the pitting location, while tool wear bands were sensitive to pitting corrosion in the low heat-input joints. Cr diffusion and tool wear were the main reasons for pitting. The mechanisms of pitting corrosion in the Nzs were analyzed in detail.

关键词： high nitrogen stainless steel Friction stir welding Mechanical properties Corrosion resistance heat-input

Achieving ultra-high strength friction stir welded joints of high nitrogen stainless steel by forced water cooling

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Journal of Materials Science & Technology 2018年第11期34卷 2183-2188页

作者： h.zhang d.Wang p.Xue L.h.Wu d.R.N B.L.Xiao z.y.Ma Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of Sciences72 Wenhua RoadShenyang 110016China University of Chinese Academy of Sciences 19 Yuquan RoadBeijing 100049China

The microstructure and properties of water-cooled and air-cooled friction stir welded（FSW） ultra-high strength high nitrogen stainless steel joints were comparatively studied. With additional rapid cooling by flowing water, the peak temperature and duration at elevated temperature during FSW were significantly reduced. Compared to those in the air-cooled joint, nugget zone with finer grains（900 nm） and heat affected zone with higher dislocation density were successfully obtained in the water-cooled joint,leading to significantly improved mechanical properties. The wear of the welding tool was significantly reduced with water cooling, resulting in better corrosion resistance during the immersion corrosion test.

关键词： Friction stir welding Stainless steels Mechanical properties Corrosion

Anisotropic time-dependent behaviors of shale under direct shearing and associated empirical creep models

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Journal of Rock Mechanics and Geotechnical engineering 2024年第4期16卷 1262-1279页

作者： yachen Xie Michael z.hou hejuan Liu Cunbao Li Shenzhen Key Laboratory of deep engineering Sciences and Green energy Shenzhen UniversityShenzhen518060China Institute of Subsurface energy Systems Clausthal University of TechnologyClausthal-Zellerfeld38678Germany State Key Laboratory of Geomechanics and Geotechnical engineering Institute of Rock and Soil MechanicsChinese Academy of SciencesWuhan430071China

Understanding the anisotropic creep behaviors of shale under direct shearing is a challenging *** this context,we conducted shear-creep and steady-creep tests on shale with five bedding orientations (i.e.0°,30°,45°,60°,and 90°),under multiple levels of direct shearing for the first *** results show that the anisotropic creep of shale exhibits a significant stress-dependent *** a low shear stress,the creep compliance of shale increases linearly with the logarithm of time at all bedding orientations,and the increase depends on the bedding orientation and creep *** high shear stress conditions,the creep compliance of shale is minimal when the bedding orientation is 0°,and the steady-creep rate of shale increases significantly with increasing bedding orientations of 30°,45°,60°,and 90°.The stress-strain values corresponding to the inception of the accelerated creep stage show an increasing and then decreasing trend with the bedding orientation.A semilogarithmic model that could reflect the stress dependence of the steady-creep rate while considering the hardening and damage process is *** model minimizes the deviation of the calculated steady-state creep rate from the observed value and reveals the behavior of the bedding orientation's influence on the steady-creep *** applicability of the five classical empirical creep models is quantitatively *** shows that the logarithmic model can well explain the experimental creep strain and creep rate,and it can accurately predict long-term shear creep *** on an improved logarithmic model,the variations in creep parameters with shear stress and bedding orientations are *** abovementioned findings,a mathematical method for constructing an anisotropic shear creep model of shale is proposed,which can characterize the nonlinear dependence of the anisotropic shear creep behavior of shale on the bedding orientation.

关键词： Rock anisotropy direct shear creep Creep compliance Steady-creep rate empirical model Creep constitutive model