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A method for analyzing on-line video images of crystallization at high-solid concentrations

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Particuology 2008年第1期6卷 9-15页

作者： Jian Wan Cai y. ma Xue Z. Wang Institute of Particle Science and Engineering School of Process Environmental and Materials Engineering University of Leeds Leeds LS2 9JT UK

Recent research has demonstrated that on-line video imaging is a very promising technique for monitoring crystallization processes. The bottleneck in applying the technique for real-time closed-loop control is considered as image analysis that needs to be robust, fast and able to handle varied image qualities due to temporal variations of operating conditions such as mixing and solid concentrations. Image analysis at highsolid concentrations turns out to be extremely challenging because crystals tend to overlap or attach to each other and the boundaries between the crystals are usually ambiguous. This paper presents an image segmentation algorithm that can effectively deal with images taken at high-solid concentrations. The method segments crystals attached to each other along the mostly related concave points on the contours of crystal blocks. The detailed procedure is introduced with application to crystallization of L-glutamic acid in a hot-stage reactor.

关键词： Crystallization High-solid concentrations Image processing Multi-scale segmentation Watershed segmentation Crystal size distribution

Evidence for particle acceleration approaching PeV energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： LHAASO Collaboration Zhen Cao F.Aharonian Axikegu y.X.Bai y.W.Bao D.Bastieri X.J.Bi y.J.Bi W.Bian A.V.Bukevich Q.Cao W.y.Cao Zhe Cao J.Chang J.F.Chang A.M.Chen E.S.Chen H.X.Chen Liang Chen Lin Chen Long Chen M.J.Chen M.L.Chen Q.H.Chen S.Chen S.H.Chen S.Z.Chen T.L.Chen y.Chen N.Cheng y.D.Cheng M.y.Cui S.W.Cui X.H.Cui y.D.Cui B.Z.Dai H.L.Dai Z.G.Dai Danzengluobu X.Q.Dong K.K.Duan J.H.Fan y.Z.Fan J.Fang J.H.Fang K.Fang C.F.Feng H.Feng L.Feng S.H.Feng X.T.Feng y.Feng y.L.Feng S.Gabici B.Gao C.D.Gao Q.Gao W.Gao W.K.Gao M.M.Ge L.S.Geng G.Giacinti G.H.Gong Q.B.Gou M.H.Gu F.L.Guo X.L.Guo y.Q.Guo y.y.Guo y.A.Han M.Hasan H.H.He H.N.He J.y.He y.He y.K.Hor B.W.Hou C.Hou X.Hou H.B.Hu Q.Hu S.C.Hu D.H.Huang T.Q.Huang W.J.Huang X.T.Huang X.y.Huang y.Huang X.L.Ji H.y.Jia K.Jia K.Jiang X.W.Jiang Z.J.Jiang M.Jin M.M.Kang I.Karpikov D.Kuleshov K.Kurinov B.B.Li C.M.Li Cheng Li Cong Li D.Li F.Li H.B.Li H.C.Li Jian Li Jie Li K.Li S.D.Li W.L.Li W.L.Li X.R.Li Xin Li y.Z.Li Zhe Li Zhuo Li E.W.Liang y.F.Liang S.J.Lin B.Liu C.Liu D.Liu D.B.Liu H.Liu H.D.Liu J.Liu J.L.Liu M.y.Liu R.y.Liu S.M.Liu W.Liu y.Liu y.N.Liu Q.Luo y.Luo H.K.Lv B.Q.ma L.L.ma X.H.ma J.R.mao Z.Min W.Mitthumsiri H.J.Mu y.C.Nan A.Neronov L.J.Ou P.Pattarakijwanich Z.y.Pei J.C.Qi M.y.Qi B.Q.Qiao J.J.Qin A.Raza D.Ruffolo A.Sáiz M.Saeed D.Semikoz L.Shao O.Shchegolev X.D.Sheng F.W.Shu H.C.Song yu.V.Stenkin V.Stepanov y.Su D.X.Sun Q.N.Sun X.N.Sun Z.B.Sun J.Takata P.H.T.Tam Q.W.Tang R.Tang Z.B.Tang W.W.Tian C.Wang C.B.Wang G.W.Wang H.G.Wang H.H.Wang J.C.Wang Kai Wang Kai Wang L.P.Wang L.y.Wang P.H.Wang R.Wang W.Wang X.G.Wang X.y.Wang y.Wang y.D.Wang y.J.Wang Z.H.Wang Z.X.Wang Zhen Wang Zheng Wang D.M.Wei J.J.Wei y.J.Wei T.Wen C.y.Wu H.R.Wu Q.W.Wu S.Wu X.F.Wu y.S.Wu S.Q.Xi J.Xia G.M.Xiang D.X.Xiao G.Xiao y.L.Xin y.Xing D.R.Xiong Z.Xiong D.L.Xu R.F.Xu R.X.Xu W.L.Xu L.Xue D.H.yan J.Z.yan T.yan C.W.yang C.y.yang F.yang F.F.yang L.L.yang M.J.yang R.Z.yang W.X.yang y.H.yao Z.G.yao L.Q.yin N.yin X.H.you Z.y.you y.H.yu Q.yuan H.yue H.D.Zeng T.X.Zeng W.Zeng M.Zha B.B.Zhang F.Zhang H.Zhang 不详 Key Laboratory of Particle Astrophysics&Experimental Physics Division&Computing Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China TIANFU Cosmic Ray Research Center ChengduChina Dublin Institute for Advanced Studies 31 Fitzwilliam Place2 DublinIreland max-Planck-Institut for Nuclear Physics P.O.Box 103980Heidelberg 69029Germany School of Physical Science and Technology&School of Information Science and Technology Southwest Jiaotong UniversityChengdu 610031China School of Astronomy and Space Science Nanjing UniversityNanjing 210023China Center for Astrophysics Guangzhou UniversityGuangzhou 510006China Tsung-Dao Lee Institute&School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghai 200240China Institute for Nuclear Research of Russian Academy of Sciences Moscow 117312Russia Hebei Normal University Shijiazhuang 050024China University of Science and Technology of China Hefei 230026China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark matter and Space Astronomy&Key Laboratory of Radio Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210023China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311121China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China School of Physics and Astronomy Yunnan UniversityKunming 650091China Key Laboratory of Cosmic Rays(Tibet University) Ministry of EducationLhasa 850000China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China School of Physics and Astronomy(Zhuhai)&School of Physics(Guangzhou)&Sino-French Institute of Nuclear Engineering and Technology(Zhuhai) Sun Yat-sen UniversityZhuhai 519000&Guangzhou 510275GuangdongChina Institute of Frontier and Interdisciplinary Science Shandong UniversityQingdao 266237China APC UniversitéParis Cité

Theγ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays(CRs)accelerated by the shock of supernova remnant(SNR)W51C and the dense molecular clouds in the adjacent star-forming region,***,the maximum acceleration capability of W51C for CRs remains *** on observations conducted with the Large High Altitude Air Shower Observatory(LHAASO),we report a significant detection ofγrays emanating from the W51 complex,with energies from 2 to 200 *** LHAASO measurements,for the first time,extend theγ-ray emission from the W51 complex beyond 100 TeV and reveal a significant spectrum bending at tens of *** combining the"π^(0)-decay bump"featured data from Fermi-LAT,the broadbandγ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision *** observed spectral bending feature suggests an exponential cutoff at~400 TeV or a power-law break at~200 TeV in the CR proton spectrum,most likely providing the first evidence of SNRs serving as CR accelerators approaching the PeV ***,two young star clusters within W51B could also be theoretically viable to produce the most energeticγrays observed by *** findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs.

关键词： UHE c-ray Cosmic rays SNR W51C Star clusters

Fulminant myocarditis induced by SARS-CoV-2 infection without severe lung involvement:insights into COvID-19 pathogenesis

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Journal of Genetics and Genomics 2024年第6期51卷 608-616页

作者： Han Du Zhongtao Du Liang Wang Hong Wang Mingjun Jia Chunge Zhang yun Liu Cheng Zhang ya Zhang Ruifeng Zhang Shuang Zhang Ning Zhang Zhenghai ma Chen Chen Wenjun Liu Hui Zeng George F.Gao Xiaotong Hou yuhai Bi College of Life Science and Technology Xinjiang UniversityUrumchiXinjiang 830046China CAS Key Laboratory of Pathogen Microbiology and Immunology Institute of MicrobiologyCenter for Influenza Research and Early-warning(CASCIRE)CAS-TWAS Center of Excellence for Emerging Infectious Diseases(CEEID)Chinese Academy of SciencesBeijing 100101China Beijing Anzhen Hospital Capital Medical UniversityBeijing 100029China College of Veterinary Medicine Shanxi Agricultural UniversityTaiyuanShanxi 030031China University of Chinese Academy of Sciences Beijing 100049China Beijing Shijitan Hospital Capital Medical UniversityBeijing 100038China

Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection often leads to pulmonary *** sequelae,including myocarditis and heart failure,have also been ***,the study presents two fulminant myocarditis cases infected by SARS-CoV-2 exhibiting remarkable elevation of cardiac biomarkers without significant pulmonary injury,as determined by imaging *** staining reveals the viral antigen within cardiomyocytes,indicating that SARSCoV-2 could directly infect the *** full viral genomes from respiratory,anal,and myocardial specimens are obtained via next-generation *** analyses of the whole genome and spike gene indicate that viruses in the myocardium/pericardial effusion and anal swabs are closely related and cluster together yet diverge from those in the respiratory *** addition,unique mutations are found in the anal/myocardial strains compared to the respiratory strains,suggesting tissue-specific virus mutation and *** findings indicate genetically distinct SARS-CoV-2 variants have infiltrated and disseminated within myocardial tissues,independent of pulmonary injury,and point to different infection routes between the myocardium and respiratory tract,with myocardial infections potentially arising from intestinal *** findings highlight the potential for systemic SARS-CoV-2 infection and the importance of a thorough multi-organ assessment in patients for a comprehensive understanding of thepathogenesisof COVID-19.

关键词： COVID-19 SARS-CoV-2 Fulminant myocarditis Myocardium Infection

Bi_(2)Te_(3)基热电材料中的声子工程

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硅酸盐学报 2024年第1期52卷 203-217页

作者：刘志愿管希成李周马妮马俊杰巴倩夏爱林晋传贵安徽工业大学材料科学与工程学院安徽马鞍山243002 安徽工业大学先进金属材料绿色制备与表面技术教育部重点实验室安徽马鞍山243002 安徽大学材料科学与工程学院合肥230601 中国科学技术大学化学与材料科学学院合肥230026

Bi_(2)Te_(3)基合金因其优异的电输运性能和较低热导率在低温区热电材料中备受关注。然而由Bi_(2)Te_(3)基合金制造的热电发电或制冷器件转化效率仍较低,因此进一步提升Bi_(2)Te_(3)基材料的热电优值zT是关键。由于晶格热导率与电性能... 详细信息

Bi_(2)Te_(3)基合金因其优异的电输运性能和较低热导率在低温区热电材料中备受关注。然而由Bi_(2)Te_(3)基合金制造的热电发电或制冷器件转化效率仍较低,因此进一步提升Bi_(2)Te_(3)基材料的热电优值zT是关键。由于晶格热导率与电性能参数关联较少,在热电性能参数中较为独立,因此,在不影响电性能的前提下,通过声子工程降低晶格热导率成为提升zT值的重要方法。本文主要综述了近年来通过纳米改性、超晶格结构、纳米复合、掺杂和引入位错阵列等声子工程优化Bi_(2)Te_(3)基材料热电性能的主要研究进展。通过这些优化手段可以显著降低材料的比热容、声子群速度或声子平均自由程,Bi_(2)Te_(3)基材料的晶格热导率显著降低,热电性能大幅提升,为热电器件的应用提供科学和技术支撑。

关键词：碲化铋基热电材料声子工程晶格热导率热电性能

Biallelic variants in RBM42 cause a multisystem disorder with neurological,facial,cardiac,and musculoskeletal involvement

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Protein & Cell 2024年第1期15卷 52-68页

作者： yiyao Chen Bingxin yang Xiaoyu Merlin Zhang Songchang Chen Minhui Wang Liya Hu Nina Pan Shuyuan Li Weihui Shi Zhenhua yang Li Wang yajing Tan Jian Wang yanlin Wang Qinghe Xing Zhonghua ma Jinsong Li He-Feng Huang Jinglan Zhang Chenming Xu Institutes of Biomedical Sciences Fudan UniversityShanghai 200032China bstetrics and Gynecology Hospital Institute of Reproduction and DevelopmentFudan UniversityShanghai 200011China Intermational Peace matermity and Child Health Hospital School of MedicineShanghai Jiao Tong UniversityShanghai 200030China Shanghai Key Laboratory of Embryo Original Diseases Shanghai 200030China State Key Laboratory of Cell Biology Shanghai Key Laboratory of Molecular AndrologyShanghai Institute of Biochemistry and Cell BiologyCAS Center for Excellence in Molecular Cell ScienceUniversity of Chinese Academy of SciencesChinese Academy of SciencesShanghai 200031China State Key Laboratory of Rice Biology the Key Laboratory of Molecular Biology of Crop Pathogens and InsectsInstitute of BiotechnologyZhejiang UniversityHangzhou 310058China Verna and marrs McLean Department of Biochemistry and Molecular Biology Baylor College of MedicineHoustonTX 77030USA Children's hospital of Fudan University Shanghai 201102China School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China School of Life Science Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024ZhejiangChina Research Units of Embryo Original Diseases Chinese Academy of Medical Sciences(No.2019RU056)Shanghai 200011China

Here,we report a previously unrecognized syndromic neurodevelopmental disorder associated with biallelic loss-of-function variants in the RBM42 *** patient is a 2-year-old female with severe central nervous system(CNs)abnormalities,hypotonia,hearing loss,congenital heart defects,and dysmorphic facial *** whole-exome sequencing(WEs)reveals that the patient has two compound heterozygous variants,c.304C>T(p.R102*)and c.1312G>A(p.A438T),in the RBM42 gene which encodes an integral component of splicing complex in the RNA-binding motif protein *** p.A438T variant is in the RRM domain which impairs RBM42 pro-tein stability in ***,p.A438T disrupts the interaction of RBM42 with hnRNP K,which is the causa-tive gene for Au-Kline syndrome with overlapping disease characteristics seen in the index *** human R102*or A438T mutant protein failed to fully rescue the growth defects of RBM42 ortholog knockout△FgRbp1 in Fusarium while it was rescued by the wild-type(WT)human RBM42.A mouse model carying Rbm42 compound heterozygous variants,c.280C>T(p.Q94*)and c.1306_1308delinsACA(p.A436T),demonstrated gross fetal develop-mental defects and most of the double mutant animals died by ***-seq data confirmed that Rbm42 was involved in neurological and myocardial functions with an essential role in alternative splicing(As).Overall,we present clinical,genetic,and functional data to demonstrate that defects in RBM42 constitute the underlying etiology of a new neurodevelopmental disease which links the dysregulation of global AS to abnormal embryonic development.

关键词： RBM42 gene RNA-binding protein neurodevelopmental disorder Au-Kline syndrome alternative splicing

Recent progress on the study of asymmetric vortex flow over slender bodies

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Acta Mechanica Sinica 2008年第5期24卷 475-487页

作者： X.y.Deng W.Tian B.F.ma y.K.Wang Key Laboratory of Fluid Mechanics Ministry of EducationBeihang University100083 BeijingChina

The investigations of forebody vortex flow and its flow control have great importance in both academic field and engineering application areas. A large number of papers and many review papers have been published. However in this research field of forebody asymmetric vortices, three problems such as tip perturbation effect, Reynolds number effect and flow instability are less studied and thus not understood completely. So many researches are still working on the issues in recent years. The present paper attempts to provide a review of recent research progress on first two problems. The first problem is mainly concerned with how the vortex flow evolves after tip perturbation; how to solve the problem of repeatability and reproducibility of wind tunnel testing data; how to develop a conception of active flow control technique with tip perturbation based on the study of vortex flow response to tip perturbation. For the second problem one is mainly concerned that how the asymmetric vortices are developed with the increase of Reynolds number; how to classify the vortex flow patterns in different Reynolds number regimes; how to develop an appropriate boundary layer transition technique to simulate flows at high Reynolds number in the convention wind tunnels. Finally, some important ques- tions that deserve answers are proposed in the concluding remarks.

关键词： High angle of attack aerodynamics ,Asymmetric vortex Tip perturbation Slender body ,Reynolds number effect

政策工具视角下我国武术政策文本分析及量化评价

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北京体育大学学报 2024年第6期47卷 81-92页

作者：马文友刘月湖南师范大学体育学院湖南长沙410012

目的:通过分析我国武术政策文本,了解我国武术政策的制定情况,探讨其倾向性与合理性。方法:借助Nvivo12软件,利用Howlett&Ramesh的政策工具分类理论对武术政策文本进行内容分析,同时依据我国武术政策实际情况构建PMC指数模型,对所选取... 详细信息

目的:通过分析我国武术政策文本,了解我国武术政策的制定情况,探讨其倾向性与合理性。方法:借助Nvivo12软件,利用Howlett&Ramesh的政策工具分类理论对武术政策文本进行内容分析,同时依据我国武术政策实际情况构建PMC指数模型,对所选取的武术政策文本内容进行定性化的描述以及定量化的评价。结果:经选取共纳入32篇政策文件以及258条政策节点,将选取的政策划分为X维度、y维度。其中,X维度包括自愿型(22.86%)、强制型(47.29%)和混合型工具(29.85%);y维度包括武术段位、武术活动、武术文化、武术管理与武术推广。武术段位制是武术政策的重要内容;武术政策的最终目标是推广普及武术。由PMC指数可知,我国武术政策文本总体评级为可接受,优秀为P6(7.00)。武术政策文本主要是在政策重点(X6)、政策受体(X8)、激励措施(X9)方面存在不足。结论:应注重武术政策的内生动力,明确政策制定目标,紧抓重点,重视短中长期目标的协同规划;加强政策间的协调与配合,形成政策合力,建立动态的政策调整机制,根据实际情况对政策进行适时处理;丰富武术政策内容,构建各参与主体均衡发展的组织体系,激励人才培养,合理规划资金投入,推进激励、保障措施及机制改革内容具体化,鼓励社会参与,拓宽政策受体。

关键词：政策工具武术政策内容分析法 PMC指数模型量化评价

初夏东北冷涡指数的建立与分析(1961-2010)

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全球变化数据学报（中英文） 2024年第1期8卷 104-109,V0104-V0109页

作者：何丽烨马宁郭军天津市气候中心天津300074

东北冷涡是东亚中高纬度地区的重要天气系统,其频繁活动能够导致明显的气温和降水异常,具有显著的“气候效应”。使用水平分辨率为2.5°×2.5°、时间分辨率为逐日的NCEP/NCAR(美国国家环境预报中心和国家大气研究中心)再分析资料,研究... 详细信息

东北冷涡是东亚中高纬度地区的重要天气系统,其频繁活动能够导致明显的气温和降水异常,具有显著的“气候效应”。使用水平分辨率为2.5°×2.5°、时间分辨率为逐日的NCEP/NCAR(美国国家环境预报中心和国家大气研究中心)再分析资料,研究时段取1961–2010年。根据东北冷涡天气学定义,将符合下述条件的天气系统定义为一次冷涡天气过程:(1)在500hPa等压面上至少能分析出一根闭合等高线,并有冷中心或明显冷槽配合的低压环流系统;(2)冷涡中心出现在(35°N–60°N,115°E–145°E)范围内;(3)冷涡在上述地区的生命史为3天或3天以上。考虑海河流域的地理位置,根据逐年东北冷涡低压中心在西涡范围(115°E–125°E)达到的最南位置,界定对初夏(6月,下同)海河流域降水有显著影响的东北冷涡活动关键区域(38°N–48°N,115°E–125°E),统计出冷涡中心频次标准化值,形成初夏东北冷涡指数数据集(1961–2010)。数据集包括:(1)初夏标准化东北冷涡活动指数;(2)逐年初夏东北冷涡500 hPa位势高度低压中心在115°E–125°E区域的最南位置。该数据集存储为1个Excel文件(.xlsx格式),数据量约12.5 KB。

关键词：东北冷涡初夏降水海河流域气候效应

Kinetics of Al Evaporation from Liquid U-Al Alloys in Vacuum Induction Melting

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Journal of materials Science & Technology 2015年第4期31卷 423-426页

作者： y.J.Duan B.Chen y.C.ma K.Liu materials for Special Environment Division Institute of Metal ResearchChinese Academy of Sciences

A research on kinetics of Al evaporation from liquid U—Al alloys was made in a vacuum induction melting（VIM） furnace at 1673—1843 *** evaporation rate of Al was found to be first order with respect to Al content in the *** overall mass transfer coefficient of Al was determined and it was found that the evaporation rate of Al increased with increasing *** apparent activation energy of Al evaporation at 1673-1843 K was 171.5 kJ *** value of mass transfer coefficient of Al in the liquid phase was estimated to be 3.77 × 10-6,7.41×10-6,and 9.40 × 10-6m s-1at 1673,1753,and 1843 K,***,rate determining steps were discussed and it was concluded that the evaporation rate of Al is mainly controlled by liquid phase mass transfer.

关键词： Al evaporation Kinetics Liquid U-Al alloys mass tr