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高灵敏度低频振速梯度水听器设计

中国惯性技术学报 2024年第4期32卷 399-405页

作者：马鑫张维洪连进哈尔滨工程大学水声技术全国重点实验室哈尔滨150001 海洋信息获取与安全工业和信息化部重点实验室(哈尔滨工程大学) 工业和信息化部哈尔滨150001 哈尔滨工程大学水声工程学院哈尔滨150001 宜昌测试技术研究所宜昌443003

目前振速梯度水听器存在灵敏度低、频带窄等缺点,限制其在工程上的应用。为解决以上问题,基于电化学换能原理,采用电极微机械加工工艺,设计了一种电化学换能振子,并制成高灵敏度、低频振速梯度水听器。所设计的电化学振子振速灵敏度达到... 详细信息

目前振速梯度水听器存在灵敏度低、频带窄等缺点,限制其在工程上的应用。为解决以上问题,基于电化学换能原理,采用电极微机械加工工艺,设计了一种电化学换能振子,并制成高灵敏度、低频振速梯度水听器。所设计的电化学振子振速灵敏度达到2500 V/(m/s),较动圈振子的振速灵敏度提高了19 dB,工作频带由20 Hz~200 Hz扩展到5 Hz~400 Hz,表明其具备更高的灵敏度和更宽的工作频带。振速梯度水听器在100 Hz~400 Hz频段内进行校准,结果显示纯偏导通道x和y方向的灵敏度以及混合偏导通道的灵敏度均满足每倍频程6 dB增长规律,且分别具有偶极子指向性和四极子指向性。纯偏导通道和混合偏导通道的灵敏度和指向性的测试值与理论值基本一致。

关键词：振速梯度水听器电化学振子灵敏度

High energy storage density in NaNbO_(3) antiferroelectrics with double hysteresis loop

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Journal of materiomics 2024年第5期10卷 1026-1035页

作者： Li ma Zhenpei Chen Gengguang Luo Zhiyi Che Chao Xu Dongliang Shan Zhenyong Cen Qin Feng Xiyong Chen Toyohisa Fujita ye Zhu yunya Liu Jing-Feng Li Shujun Zhang Nengneng Luo State Key Laboratory of Featured Metal materials and Life-cycle Safety for Composite Structures School of ResourcesEnvironment and MaterialsGuangxi UniversityNanning530004China School of Chemistry and Chemical Engineering Guangxi UniversityNanning530004China Department of Applied Physics Research Institute for Smart EnergyThe Hong Kong Polytechnic UniversityHung HomKowloonHong KongChina Key Laboratory of Low Dimensional materials and Application Technology of Ministry of Education School of Materials Science and EngineeringXiangtan UniversityXiangtan411105HunanChina State Key Laboratory of New Ceramics and Fine Processing School of Materials Science and EngineeringTsinghua UniversityBeijing100084China Institute for Superconducting and Electronic materials Australian Institute of Innovative MaterialsUniversity of WollongongWollongongNSW2500Australia

Antiferroelectrics(AFEs)possess great potential for high performance dielectric capacitors,due to their distinct double hysteresis loop with high maximum polarization and low remnant ***,the well-known NaNbO3 lead-free antiferroelectric(AFE)ceramic usually exhibits square-like P–E loop related to the irreversible AFE P phase to ferroelectric(FE)Q phase transition,yielding low recoverable energy storage density(Wrec).Herein,significantly improved Wrec up to 3.3 J/cm^(3) with good energy storage efficiency(η)of 42.4% was achieved in Na_(0.7)Ag_(0.3)Nb_(0.7)Ta_(0.3)O_(3)(30Agsingle bond30Ta)ceramic with well-defined double P–E loop,by tailoring the A-site electronegativity with Ag+and B-site polarizability with Ta^(5+).The Transmission Electron Microscope,Piezoresponse Force Microscope and in-situ Raman spectra results verified a good reversibility between AFE P phase and high-field-induced FE Q *** improved stability of AFE P phase,being responsible for the double P–E loop and improved Wrec,was attributed to the decreased octahedral tilting angles and cation *** mechanism was revealed by synchrotron X-ray diffraction and Scanning Transmission Electron *** work provides a good paradigm for achieving double P–E loop and high energy storage density in NaNbO_(3)-based ceramics.

关键词： Sodium niobate Antiferroelectrics Double hysteresis loop Energy storage performance Reversibility

Seismic attribute and well-log analysis for channel characterization in the upper San Andres and Grayburg formations of the Midland Basin,Texas

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Energy Geoscience

Energy Geoscience 2024年第2期5卷 263-278页

作者： Sumit Verma Esra yalçın yılmaz Laura Ortiz Sanguino Justin yandell Miles A.Henderson Robert C.Trentham Department of Geosciences The University of Texas Permian BasinOdessaTXUSA School of Geosciences The University of OklahomaNormanOKUSA

The Permian Basin is one of the most prolific,and currently one of the most active,oil and gas basins in the *** Lower Permian strata in the Permian Basin have produced more than 14 billion barrels of oil(BBO),making it the largest volume of hydrocarbon in the *** in the Midland Basin during late Leonardian through early Guadalupian(ca.272-269 ma)resulted in progradation of shelf edge and ultimately closure of the basin by Middle Permian *** analyzed a merged seismic survey covering parts of the Permian Basin(i.e.,Central Basin Platform and Midland Basin)in Andrews,Ector,and Midland Counties,*** seismic survey and well logs show the presence of gently dipping(ca.1°)clinoforms in the Upper San Andres and Grayburg Formations on the eastern edge of the Central Basin Platform and western Midland *** seismic attributes,curvature,and spectral decomposition identify low sinuosity slope channels oriented north-south,but such channels do not appear beyond the *** shelf edge shifts from north to south during deposition of the Upper San Andres and Grayburg *** identify five basinward shifts noted by the migration of the shelf edge toward the basin center and the presence of channel features along the depositional *** petrophysical analysis indicates that channels cut into carbonate rocks and are filled by siliciclastic sediments;this interpretation is supported by the most negative curvature anomalies along the channel axes caused by the differential compaction between the carbonate and siliciclastic *** are a few channels with a northwest-southeast strike,which matches the direction of the Concho Lineament observed by satellite *** observations are consistent with previous interpretations of the northern Midland Basin closure during Middle-Late Permian time.

关键词： Permian shelf carbonate

Two-dimensional atomically thin Pt layers on MXenes: The role of electronic effects during catalytic dehydrogenation of ethane and propane

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Nano Research 2024年第3期17卷 1251-1258页

作者： Zhe Li Tobias K.Misicko Fan yang Xiaopeng Liu Zhenwei Wu Xiaoyang Gao Tao ma Jeffrey T.Miller Daniela S.mainardi Collin D.Wick Zhenhua Zeng yang Xiao yue Wu Department of Chemical and Biological Engineering Iowa State University618 Bissell RoadAmesIA 50011USA Institute for Micromanufacturing Louisiana Tech University505 Tech DriveRustonLA 71272USA Davidson School of Chemical Engineering Purdue University480 Stadium Mall DriveWest LafayetteIN 47907USA Michigan Center for materials Characterization University of Michigan2800 Plymouth RdAnn Arbor MI 48109USA College of Engineering and Science Louisiana Tech UniversityRustonLA 71272USA

Atomically thin Pt nanolayers were synthesized on the surface of Mo2TiC2 MXenes and used for the catalytic dehydrogenation of ethane and propane into ethylene and propylene,two important chemicals for the petrochemical *** compared with Pt nanoparticles,the atomically thin Pt nanolayer catalyst showed superior coke-resistance(no deactivation for 24 h),high activity(turnover frequencies(TOFs)of 0.4–1.2 s^(-1)),and selectivity(>95%)toward ethylene and *** unique Pt nanolayer has a similar geometric surface to Pt nanoparticles,enabling the investigations of the electronic effect on the catalytic performance,where the geometric effect is *** is found that the electronic effect plays a critical role in dehydrogenative product selectivity and catalyst *** metal–support interaction is found dependent on the substrate and metal components,providing wide opportunities to explore high-performance MXene-supported metallic catalysts.

关键词： MXene catalysis alkane dehydrogenation nanolayers

Recombinant chitinase-3-like protein 1 alleviates learning and memory impairments via M2 microglia polarization in postoperative cognitive dysfunction mice

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Neural Regeneration Research 2025年第9期20卷 2727-2736页

作者： yujia Liu Xue Han yan Su yiming Zhou Minhui Xu Jiyan Xu Zhengliang ma Xiaoping Gu Tianjiao Xia Department of Anesthesiology Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingJiangsu ProvinceChina Medical School Nanjing UniversityNanjingJiangsu ProvinceChina Jiangsu Key Laboratory of Molecular Medicine Nanjing UniversityNanjingJiangsu ProvinceChina State Key Laboratory of Pharmaceutical Biotechnology Nanjing UniversityNanjingJiangsu ProvinceChina Department of Anesthesiology Zhongshan HospitalFudan UniversityShanghaiChina

Postoperative cognitive dysfunction is a seve re complication of the central nervous system that occurs after anesthesia and surgery,and has received attention for its high incidence and effect on the quality of life of *** date,there are no viable treatment options for postoperative cognitive *** identification of postoperative cognitive dysfunction hub genes could provide new research directions and therapeutic targets for future *** identify the signaling mechanisms contributing to postoperative cognitive dysfunction,we first conducted Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses of the Gene Expression Omnibus GSE95426 dataset,which consists of mRNAs and long non-coding RNAs differentially expressed in mouse hippocampus3 days after tibial *** dataset was enriched in genes associated with the biological process"regulation of immune cells,"of which Chill was identified as a hub ***,we investigated the contribution of chitinase-3-like protein 1 protein expression changes to postoperative cognitive dysfunction in the mouse model of tibial fractu re *** were intraperitoneally injected with vehicle or recombinant chitinase-3-like protein 124 hours post-surgery,and the injection groups were compared with untreated control mice for learning and memory capacities using the y-maze and fear conditioning *** addition,protein expression levels of proinflammatory factors(interleukin-1βand inducible nitric oxide synthase),M2-type macrophage markers(CD206 and arginase-1),and cognition-related proteins(brain-derived neurotropic factor and phosphorylated NMDA receptor subunit NR2B)were measured in hippocampus by western *** with recombinant chitinase-3-like protein 1 prevented surgery-induced cognitive impairment,downregulated interleukin-1βand nducible nitric oxide synthase expression,and upregulated CD206,arginase-1,pNR2B,and brain-derived neurotropic factor expr

关键词： Chil1 hippocampus learning and memory M2 microglia neuroinflammation postoperative cognitive dysfunction(POCD) recombinant CHI3L1

Assessing risk of Bombali virus spillover to humans by mutagenesis analysis of viral glycoprotein

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hLife 2024年第1期2卷 32-42页

作者： Lincan Li Tianyu Gan Ziyue ma yi Huang Jin Zhong Unit of Viral Hepatitis CAS Key Laboratory of Molecular Virology and ImmunologyShanghai Institute of Immunity and InfectionCenter for Biosafety Mega-ScienceChinese Academy of SciencesShanghaiChina University of Chinese Academy of Sciences BeijingChina ShanghaiTech University ShanghaiChina Wuhan National Biosafety Laboratory Center for Biosafety Mega-ScienceChinese Academy of SciencesHubeiChina

Ebolaviruses,such as the highly pathogenic Ebola virus(EBOV),belong to the family Filoviridae and have caused out-breaks of severe and fatal hemorrhagic fever over the past *** virus(BOMV)is a newly discovered ebolavirus from bats with unknown potential to infect *** most ebolaviruses,the interaction between viral glycoprotein(GP)and host receptor Niemann-Pick C1(NPC1)is crucial for viral entry and determines host ***,we analyzed the BOMV GP-mediated virus entry into human cells using our recently developed EBOV transcription-and replication-competent virus-like particle(trVLP)*** demonstrated that while BOMV GP can be efﬁciently incorporated into trVLPs,it is inefﬁcient in mediating trVLP entry into human ***,BOMV GP-mediated virus entry into human cells can be signiﬁcantly enhanced by a few mutations in the NPC1-binding domain of ***,we showed that these mutations increase the binding of BOMV-GP to human *** summary,our results suggested that although wild-type BOMV does not efﬁciently infect human cells,the emergence of mutations in viral GP may boost its ability to spill over to humans,highlighting the importance of monitoring BOMV GP evolution in preventing potential BOMV spillover events.

关键词： Bombali virus glycoprotein entry Ebola virus Niemann-Pick C1

Bioorthogonal microglia-inspired mesenchymal stem cell bioengineering system creates livable niches for enhancing ischemic stroke recovery via the hormesis

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1412-1427页

作者： Jianpei Xu y.nzhe Sun yang you yuwen Zhang Dan Huang Songlei Zhou yipu Liu Shiqiang Tong Fenfen ma Qingxiang Song Chengxiang Dai Suke Li Jigang Lei Zhihua Wang Xiaoling Gao Jun Chen Shanghai Pudong Hospital&Department of Pharmaceutics School of PharmacyFudan UniversityShanghai 201203China Key Laboratory of Smart Drug Delivery Ministry of EducationSchool of PharmacyFudan UniversityShanghai 201203China Department of Pharmacology and Chemical Biology State Key Laboratory of Oncogenes and Related GenesShanghai Universities Collaborative Innovation Center for Translational MedicineShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Emergency Shanghai Pudong HospitalFudan University Pudong Medical CenterShanghai 201399China Institute of Science and Technology for Brain-Inspired Intelligence&Department of Neurology Fudan UniversityShanghai 201203China Department of Rehabilitation Medicine Huashan HospitalFudan UniversityShanghai 201203China Daxing Research Institute University of Science and Technology BeijingBiomedical Industry BaseZhongguancun Science and Technology ParkBeijing 102600China Cellular Biomedicine Group Inc. Shanghai 201210China

Mesenchymal stem cells(MSCs)experience substantial viability issues in the stroke infarct region,limiting their therapeutic efficacy and clinical *** levels of deadly reactive oxygen radicals(ROS)and proinflammatory cytokines(PC)in the infarct milieu kill transplanted MSCs,whereas low levels of beneficial ROS and PC stimulate and improve engrafted MSCs’*** on the intrinsic hormesis effects in cellular biology,we built a microglia-inspired MSC bioengineering system to transform detrimental high-level ROS and PC into vitality enhancers for strengthening MSC *** system is achieved by bioorthogonally arming metabolic glycoengineered MSCs with microglial membrane-coated nanoparticles and an antioxidative extracellular protective *** this system,extracellular ROSscavenging and PC-absorbing layers effectively buffer the deleterious effects and establish a microlivable niche at the level of a single MSC for ***,the infarct’s inanimate milieu is transformed at the tissue level into a new living niche to facilitate *** engineered MSCs achieved viability five times higher than natural MSCs at seven days after transplantation and exhibited a superior therapeutic effect for stroke recovery up to 28 *** vitality-augmented system demonstrates the potential to accelerate the clinical translation of MSC treatment and boost stroke recovery.

关键词： Ischemic stroke Mesenchymal stem cell Cell engineering Hormesis effect Bioorthogonal chemistry Microglia Reactive oxygen spices Proinflammatory cytokines

Two-photon live imaging of direct glia-to-neuron conversion in the mouse cortex

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Neural Regeneration Research 2024年第8期19卷 1781-1788页

作者： Zongqin Xiang Shu He Rongjie Chen Shanggong Liu Minhui Liu Liang Xu Jiajun Zheng Zhouquan Jiang Long ma ying Sun yongpeng Qin yi Chen Wen Li Xiangyu Wang Gong Chen Wenliang Lei Guangdong-Hong Kong-macao Institute of CNS Regeneration(GHMICR) Jinan UniversityGuangzhouGuangdong ProvinceChina Department of Neurosurgery The First Affiliated HospitalJinan UniversityGuangzhouGuangdong ProvinceChina Laboratory for Neuroimmunology in Health and Diseases Guangzhou First People’s HospitalSchool of MedicineSouth China University of TechnologyGuangzhouGuangdong ProvinceChina VIB-KU Leuven Center for Brain&Disease Research LeuvenFlemish RegionBelgium

Over the past decade,a growing number of studies have reported transcription factor-based in situ reprogramming that can directly conve rt endogenous glial cells into functional neurons as an alternative approach for n euro regeneration in the adult mammalian central ne rvous *** r,many questions remain regarding how a terminally differentiated glial cell can transform into a delicate neuron that forms part of the intricate brain *** addition,concerns have recently been raised around the absence of astrocyte-to-neuron conversion in astrocytic lineage-tra cing *** this study,we employed repetitive two-photon imaging to continuously capture the in situ astrocyte-to-neuron conversion process following ecto pic expression of the neural transcription factor NeuroD1 in both prolife rating reactive astrocytes and lineage-tra ced astrocytes in the mouse ***-lapse imaging over several wee ks revealed the ste p-by-step transition from a typical astrocyte with numero us short,tapered branches to a typical neuro n with a few long neurites and dynamic growth cones that actively explored the local *** addition,these lineage-converting cells were able to migrate ra dially or to ngentially to relocate to suitable ***,two-photon Ca2+imaging and patch-clamp recordings confirmed that the newly generated neuro ns exhibited synchronous calcium signals,repetitive action potentials,and spontaneous synaptic responses,suggesting that they had made functional synaptic connections within local neural *** conclusion,we directly visualized the step-by-step lineage conversion process from astrocytes to functional neurons in vivo and unambiguously demonstrated that adult mammalian brains are highly plastic with respect to their potential for neuro regeneration and neural circuit reconstruction.

关键词： astrocyte-to-neuron conversion Ca2+imaging direct lineage conversion glia astrocyte in vivo reprogramming lineage-tracing mice NeuroD1 neuron two-photon imaging

香港《公民、经济与社会科课程指引》的特点与启示

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课程．教材．教法 2024年第5期44卷 94-102页

作者：周敏马早明岭南师范学院华南师范大学教育科学学院国家教材建设重点研究基地华南师范大学港澳台教材综合研究基地广州510631 华南师范大学国际与比较教育研究所广州510631

为增强香港青少年的国家认同感,保障国民教育的连续性,香港特区政府于2022年10月明确提出,重新冠名“公民、经济与社会”以代替“生活与社会”课程,并颁布了新的课程指引。课程指引更新的依据是落实“爱国者治港”的根本要求、完善德育... 详细信息

为增强香港青少年的国家认同感,保障国民教育的连续性,香港特区政府于2022年10月明确提出,重新冠名“公民、经济与社会”以代替“生活与社会”课程,并颁布了新的课程指引。课程指引更新的依据是落实“爱国者治港”的根本要求、完善德育类课程体系建设的实然要求和全面推进爱国主义教育进课程教材的现实诉求。比较香港地区初中“生活与社会科”与“公民、经济与社会科”的课程指引,发现在课程宗旨、学习目标和课程内容方面,新版课程指引发生了显著变化。面对修订后的课程指引,在推动课程的全面实施中要以服务课程修订为目标,培养爱国爱港教师队伍;以遵循课程指引为原则,推动爱国主义教育进课程教材;以课程实施为契机,构建更为系统的德育课程体系。

关键词：香港课程爱国主义教育公民、经济与社会科生活与社会科