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XOR spin logic operated by unipolar current based on field-free spin-orbit torque switching induced by a lateral interface

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Rare Metals 2024年第8期43卷 3868-3875页

作者： y.n-Ru Li Mei-y.n y.ng Guo-Qiang yu Bao-Shan Cui Jin-Biao Liu y.ng-Liang Li Qi-Ming shao Jun Luo Key Laboratory of Microelectronic Devices and Integrated Technology Institute of MicroelectronicsChinese Academy of Sciences(IMECAS)Beijing 100029China University of Chinese Academy of Sciences(UCAS) Beijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China Institute of Physics Chinese Academy of SciencesBeijing 100190China Key Laboratory for Magnetism and Magnetic Materials of Ministry of Education Lanzhou UniversityLanzhou 730000China Department of Electronic and Computer Engineering The Hong Kong University of Science and TechnologyHong Kong 999077China

Spin logics have emerged as a promising avenue for the development of logic-in-memory *** particular,the realization of XOR spin logic gates using a single spin-orbit torque device shows great potential for low-power stateful logic circuits in the next *** this study,we successfully obtained the XOR logic gate by utilizing a spin-orbit torque device with a lateral interface,which was created by local ion implantation in the Ta/Pt/Co/Ta Hall device exhibiting perpendicular magnetic *** angle of the lateral interface is set at 45°relative to the current direction,leading to the competition between symmetry breaking and current-driven néel-type domain wall ***,the field-free magnetic switching reversed is realized by the same sign of current amplitude at this *** on this field-free magnetic switching behavior,we successfully proposed an XOR logic gate that could be implemented using only a single spin-orbit torque Hall *** study provides a potentially viable approach toward efficient spin logics and in-memory computing architectures.

关键词： Filed-free magnetic switching Spin-orbit torque XOR logic gate Lateral interface

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Characterization of the spoilage strength of Aeromonas app. to collagen-rich chilled meat: comparative analysis

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Food Science and Human Wellness 2024年

作者： Junming Gong Liangting shao Silu Liu Xinglian Xu Huhu Wang State Key Laboratory of Meat Quality Control and Cultured Meat Development， College of Food Science and Technology， nanjing Agricultural University College of Food Science and Pharmacy， Xinjiang Agricultural University

Aeromonas spp. are commonly found in spoilage of chilled meat. Aeromonas salmonicida nCM 29 and Aeromonas salmonicida nCM 57 have been discovered the spoilage heterogeneity in degrading myofibrillar protein. In this study， the two strains were tested to uncover the discrepancy of meat spoilage in collagen-rich chilled meat and extracted collagen. The results revealed that chicken claws， riched in collagen， inoculated with nCM 29 showed higher values of total viable counts (TVC)， total volatile basic nitrogen (TVB-n)， pH， adhered cells， TCA-soluble peptides， and protease activity compared to those inoculated with nCM 57. Furthermore， nCM 29 generated higher quantity of volatile organic compounds related to meat spoilage. The collagenase (hemagglutinin protease， Hap) secreted by.nCM 29 has been identified as the key factor responsible for the observed discrepancies in spoilage， which gradually degraded collagen into peptides and hydroxyproline. The capacity of Hap to degrade type I collagen in vitro indicated that it has apparent proteolytic activity， which could reduce the average particle size and alter secondary structure of collagen. SDS-PAGE further confirmed the degradation of the β chain in collagen. These findings not only provide a theoretical basis for in-depth investigation of the meat spoilage mechanisms of Aeromonas spp.， but also encourage us to take measures to avoid the spoilage of related bacteria such as Aeromonas spp. during the preservation process.

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Spatial Distribution and Release Flux of Carbon and nitrogen Components in Glacial Watersheds of Eastern Tibetan Plateau

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Journal of Earth Science 2024年

作者： Xiaoyu Jiao Zhiwen Dong Xiang Qin Xiaoxiang Wang yaping shao State Key Laboratory of Cryosphere Sciences， northwest Institute of Eco-Environment and Resources， Chinese Academy of Sciences University of Chinese Academy of Sciences School of Geography and Information Engineering， China University of Geosciences Institute of Geophysics and Meteorology， University of Cologne

The carbon cycle stands as a cornerstone among the Earth's material cycles， carry.ng profound implications for global climate dynamics and humanity's sustenance and advancement. Additionally， nitrogen， as a vital nutrient element， plays a pivotal role in biogeochemical processes， exerting significant influence on the ecological environment within watersheds. In this study， an analysis of the carbon （C） and nitrogen （n） components in the river water of 12 alpine basins on the eastern margin of the Tibetan Plateau （TP） reveals that the average dissolved organic carbon （DOC） concentration in the river water is 0.76±0.67 mg/L， indicating a lower level compared to the global river average organic carbon content. Specifically， the average DOC concentrations were 0.42±0.22 mg/L and 1.56±0.68 mg/L in the glacial and non-glacial basins， respectively. The average dissolved inorganic carbon （DIC） concentration in the eastern TP is 27.04±20.19 mg/L， with the lowest DIC observed at Dagu Glacier and the highest at Daxia River. Furthermore， the average dissolved total carbon （DTC） concentration in glacier river water was 18.87±12.65 mg/L， contrasting with 48.23±21.07 mg/L in non-glacial basins. The mean concentration of total nitrogen （Tn） in the eastern TP averaged 0.97±0.54 mg/L， with the glacial basin registering 1.01±0.47 mg/L and the non-glacial basin at 0.89±0.70 mg/L. Evaluating the release fluxes of carbon and nitrogen across 12 river basins revealed a range of DTC emission fluxes from 0.32 to 31.02 × 109g C/a， with inorganic carbon comprising 71.0% to 99.5%. Consequently， the carbon emission flux for seven glacier basins totaled 15.91 × 109g C/a， while for the five non-glacial river basins， it reached 87.37× 109g C/a. The total Tn release fluxes across 12 small river basins amounted to 2.46 × 109g n/a， with 0.84 × 109g n/a released in glacial basins and 1.62 × 109g n/a in the non-glacial basin. This study elucidates the spatial distribution and transport mechanisms of car

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Direct Regeneration of Spent Lithium-Ion Battery Cathodes:From Theoretical Study to Production Practice

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nano-Micro Letters 2024年第10期16卷 304-336页

作者： Meiting Huang Mei Wang Liming y.ng Zhihao Wang Haoxuan yu Kechun Chen Fei Han Liang Chen Chenxi Xu Lihua Wang Penghui shao Xubiao Luo national-Local Joint Engineering Research Center of Heavy Metals Pollutants Control and Resource Utilization Nanchang Hangkong UniversityNanchang 330063People's Republic of China Key Laboratory of Hunan Province for Advanced Carbon-based Functional Materials School of Chemistry and Chemical EngineeringHunan Institute of Science and TechnologyYueyang 414006People's Republic of China College of Materials Science and Engineering Central South University of Forestry and TechnologyChangsha 410004People's Republic of China School of Life Science Jinggangshan UniversityJi'an 343009People's Republic of China

Direct regeneration method has been widely concerned by researchers in the field of battery recycling because of its advantages of in situ regeneration,short process and less pollutant *** this review,we firstly analyze the primary causes for the failure of three representative battery cathodes(lithium iron phosphate,layered lithium transition metal oxide and lithium cobalt oxide),targeting at illustrating their underly.ng regeneration mecha-nism and *** stripping of material from the collector to obtain pure cathode material has become a first challenge in recycling,for which we report several pretreatment methods currently available for subsequent regeneration *** review and discuss emphatically the research progress of five direct regeneration methods,including solid-state sintering,hydrothermal,eutectic molten salt,electrochemical and chemical lithiation ***,the application of direct regeneration technology in production practice is introduced,the problems exposed at the early stage of the industrialization of direct regeneration technol-ogy are revealed,and the prospect of future large-scale commercial production is *** is hoped that this review will give readers a comprehensive and basic understanding of direct regeneration methods for used lithium-ion batteries and promote the industrial application of direct regeneration technology.

关键词： Spent LIBs Failure reasons Cathode recycling Direct regeneration Production practice

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Bibliometric analysis of hotspots and trends of global myopia research

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 940-950页

作者： Xing-y.ng Wu Hui-Hui Fang y.n-Wu Xu y.n-Ling Zhang shao-Chong Zhang Wei-Hua y.ng Shenzhen Eye Institute Shenzhen Eye HospitalJinan UniversityShenzhen 518040Guangdong ProvinceChina School of Future Technology South China University of TechnologyGuangzhou 510641Guangdong ProvinceChina

AIM:To gain insights into the global research hotspots and trends of ***:Articles were downloaded from January 1,2013 to December 31,2022 from the Science Core Database website and were mainly statistically analyzed by bibliometrics ***:A total of 444 institutions in 87 countries published 4124 *** 2013 and 2022,China had the highest number of publications(n=1865)and the highest H-index(61).Sun yat-sen University had the highest number of publications(n=229)and the highest H-index(33).Ophthalmology is the main category in related *** from 2020 to 2022 highlight keywords of options and reference,child health(pediatrics),myopic traction mechanism,public health,and machine learning,which represent research ***:Myopia has become a hot research *** and Chinese institutions have the strongest academic influence in the field from 2013 to *** main driver of myopic research is still medical or *** study highlights the importance of public health in addressing the global rise in myopia,especially its impact on children’s *** present,a unified theoretical system is still *** surgical and therapeutic solutions must be proposed for people with different characteristics to manage and intervene refractive *** addition,the benefits of artificial intelligence(AI)models are also reflected in disease monitoring and prediction.

关键词： bibliometric analysis myopia global trends

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Circ_0053943 complexed with IGF2BP3 drives uveal melanoma progression via regulating n6-methyladenosine modification of Epidermal growth factor receptor

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Oncology Research 2024年第5期32卷 983-998页

作者： AnDI ZHAO yUE WAnG ZIJIn WAnG QInG shao QI GOnG HUI ZHU SHIyA SHEn HU LIU XUEJUAn CHEn Department of Ophthalmology The First Affiliated Hospital with Nanjing Medical UniversityNanjing210029China The First Clinical Medical College Nanjing Medical UniversityNanjing211166China Department of Ophthalmology Nanjing First HospitalNanjing Medical UniversityNanjing210006China

numerous studies have characterized the critical role of circular RnAs(circRnAs)as regulatory factors in the progression of multiple ***,the biological functions of circRnAs and their underly.ng molecular mechanisms in the progression of uveal melanoma(UM)remain *** this study,we identified a novel circRnA,circ_0053943,through re-analysis of UM microarray data and quantitative ***_0053943 was found to be upregulated in UM and to promote the proliferation and metastatic ability of UM cells in both in vitro and in vivo ***,circ_0053943 was observed to bind to the KH1 and KH2 domains of insulin-like growth factor 2 mRnA-binding protein 3(IGF2BP3),thereby enhancing the function of IGF2BP3 by stabilizing its target *** sequencing assays identified epidermal growth factor receptor(EGFR)as a target gene of circ_0053943 and IGF2BP3 at the transcriptional *** assays demonstrated that circ_0053943 exerts its biological function by stabilizing EGFR mRnA and regulating the downstream mitogen-activated protein kinase/extracellular signal-regulated kinase(MAPK/ERK)signaling ***,circ_0053943 may promote UM progression by stabilizing EGFR mRnA and activating the MAPK/ERK signaling pathway through the formation of a circ_0053943/IGF2BP3/EGFR RnA-protein ternary complex,thus providing a potential biomarker and therapeutic target for UM.

关键词： Uveal melanoma Hsa_circ_0053943 IGF2BP3 EGFR MAPK/ERK signaling pathway

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Cation effects in electrocatalytic reduction reactions:Recent advances

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Chinese Journal of Catalysis 2024年第8期63卷 16-32页

作者： Qinghui Ren Liang Xu Mengyu Lv Zhiyuan Zhang Zhenhua Li Mingfei shao Xue Duan State Key Laboratory of Chemical Resource Engineering College of ChemistryBeijing University of Chemical TechnologyBeijing 100029China College of Chemical Engineering Beijing University of Chemical TechnologyBeijing 100029China Quzhou Institute for Innovation in Resource Chemical Engineering Quzhou 324000ZhejiangChina

Electrocatalytic reduction reactions,powered by clean energy sources such as solar energy and wind,offer a sustainable method for converting inexpensive feedstocks(e.g.,CO_(2),n2/nOx,organics,and O_(2))into high-value-added chemicals or *** design and modification of electrocatalysts have been widely implemented to improve their performance in these ***,bottle-necks are encountered,making it challenging to further improve performance through catalyst development ***,cations in the electrolyte have emerged as critical factors for tuning both the activity and product selectivity of reduction *** review summarizes recent advances in understanding the role of cation effects in electrocatalytic reduction ***,we introduce the mechanisms underly.ng cation *** then provide a comprehensive overview of their application in electroreduction *** techniques and theoretical calcula-tion methods for study.ng cation effects are also ***,we address remaining challeng-es and future perspectives in this *** hope that this review offers fundamental insights and design guidance for utilizing cation effects,thereby advancing their development.

关键词： Electrocatalysis Reduction reaction Cation effect Mechanism Application

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Evidence for particle acceleration approaching PeV energies in the W51 complex

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Science Bulletin 2024年第18期69卷 2833-2841页

作者： Cao, Zhen Aharonian, F. Axikegu Bai, y.X. Bao, y.W. Bastieri, D. Bi, X.J. Bi, y.J. Bian, W. Bukevich, A.V. Cao, Q. Cao, W.y. Cao, Zhe Chang, J. Chang, J.F. Chen, A.M. Chen, E.S. Chen, H.X. Chen, Liang Chen, Lin Chen, Long Chen, M.J. Chen, M.L. Chen, Q.H. Chen, S. Chen, S.H. Chen, S.Z. Chen, T.L. Chen, y. Cheng, n. Cheng, y.D. Cui, M.y. Cui, S.W. Cui, X.H. Cui, y.D. Dai, B.Z. Dai, H.L. Dai, Z.G. Danzengluobu Dong, X.Q. Duan, K.K. Fan, J.H. Fan, y.Z. Fang, J. Fang, J.H. Fang, K. Feng, C.F. Feng, H. Feng, L. Feng, S.H. Feng, X.T. Feng, y. Feng, y.L. Gabici, S. Gao, B. Gao, C.D. Gao, Q. Gao, W. Gao, W.K. Ge, M.M. Geng, L.S. Giacinti, G. Gong, G.H. Gou, Q.B. Gu, M.H. Guo, F.L. Guo, X.L. Guo, y.Q. Guo, y.y. Han, y.A. Hasan, M. He, H.H. He, H.n. He, J.y. He, y. Hor, y.K. Hou, B.W. Hou, C. Hou, X. Hu, H.B. Hu, Q. Hu, S.C. Huang, D.H. Huang, T.Q. Huang, W.J. Huang, X.T. Huang, X.y. Huang, y. Ji, X.L. Jia, H.y. Jia, K. Jiang, K. Jiang, X.W. Jiang, Z.J. Jin, M. Kang, M.M. Karpikov, I. Kuleshov, D. Kurinov, K. Li, B.B. Li, C.M. Li, Cheng Li, Cong Li, D. Li, F. Li, H.B. Li, H.C. Li, Jian Li, Jie Li, K. Li, S.D. Li, W.L. Li, X.R. Li, Xin Li, y.Z. Li, Zhe Li, Zhuo Liang, E.W. Liang, y.F. Lin, S.J. Liu, B. Liu, C. Liu, D. Liu, D.B. Liu, H. Liu, H.D. Liu, J. Liu, J.L. Liu, M.y. Liu, R.y. Liu, S.M. Liu, W. Liu, y. Liu, y.n. Luo, Q. Luo, y. Lv, H.K. Ma, B.Q. Ma, L.L. Ma, X.H. Mao, J.R. Min, Z. Mitthumsiri, W. Mu, H.J. nan, y.C. neronov, A. Ou, L.J. Pattarakijwanich, P. Pei, Z.y. Qi, J.C. Qi, M.y. Qiao, B.Q. Qin, J.J. Raza, A. Ruffolo, D. Sáiz, A. Saeed, M. Semikoz, D. shao, L. Shchegolev, O. Sheng, X.D. Shu, F.W. Song, H.C. Stenkin, yu.V. Stepanov, V. Su, y. Sun, D.X. Sun, Q.n. Sun, X.n. Sun, Z.B. Takata, J. Tam, P.H.T. Key Laboratory of Particle Astrophysics & Experimental Physics Division & Computing Center Institute of High Energy Physics Chinese Academy of Sciences Beijing 100049 China University of Chinese Academy of Sciences Beijing 100049 China TIAnFU Cosmic Ray Research Center Chengdu China Dublin Institute for Advanced Studies 31 Fitzwilliam Place 2 Dublin Ireland Max-Planck-Institut for nuclear Physics P.O. Box 103980 Heidelberg 69029 Germany School of Physical Science and Technology & School of Information Science and Technology Southwest Jiaotong University Chengdu 610031 China School of Astronomy and Space Science Nanjing University Nanjing 210023 China Center for Astrophysics Guangzhou University Guangzhou 510006 China Tsung-Dao Lee Institute & School of Physics and Astronomy Shanghai Jiao Tong University Shanghai 200240 China Institute for nuclear Research of Russian Academy of Sciences Moscow 117312 Russia Hebei normal University Shijiazhuang 050024 China University of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics China Key Laboratory of Dark Matter and Space Astronomy & Key Laboratory of Radio Astronomy Purple Mountain Observatory Chinese Academy of Sciences Nanjing 210023 China Research Center for Astronomical Computing Zhejiang Laboratory Hangzhou 311121 China Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China School of Physics and Astronomy Yunnan University Kunming 650091 China Key Laboratory of Cosmic Rays (Tibet University) Ministry of Education Lhasa 850000 China national Astronomical Observatories Chinese Academy of Sciences Beijing 100101 China School of Physics and Astronomy (Zhuhai) & School of Physics (Guangzhou) & Sino-French Institute of nuclear Engineering and Technology (Zhuhai) Sun Yat-sen University Zhuhai 519000 & Guangzhou 510275 Guangdong China Institute of Frontier and

The γ-ray emission from the W51 complex is widely acknowledged to be attributed to the interaction between the cosmic rays (CRs) accelerated by the shock of supernova remnant (SnR) W51C and the dense molecular clouds in the adjacent star-forming region, W51B. However, the maximum acceleration capability of W51C for CRs remains elusive. Based on observations conducted with the Large High Altitude Air Shower Observatory (LHAASO), we report a significant detection of γ rays emanating from the W51 complex, with energies from 2 to 200 TeV. The LHAASO measurements, for the first time, extend the γ-ray emission from the W51 complex bey.nd 100 TeV and reveal a significant spectrum bending at tens of TeV. By combining the "π0-decay bump" featured data from Fermi-LAT, the broadband γ-ray spectrum of the W51 region can be well-characterized by a simple pp-collision model. The observed spectral bending feature suggests an exponential cutoff at ∼400 TeV or a power-law break at ∼200 TeV in the CR proton spectrum, most likely providing the first evidence of SnRs serving as CR accelerators approaching the PeV regime. Additionally, two young star clusters within W51B could also be theoretically viable to produce the most energetic γ rays observed by LHAASO. Our findings strongly support the presence of extreme CR accelerators within the W51 complex and provide new insights into the origin of Galactic CRs. © 2024 Science China Press

关键词： Cosmic rays

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Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis

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World Journal of Gastroenterology 2024年第4期30卷 318-331页

作者： yu-Zhe Cao Guang-Lei Zheng Tian-Qi Zhang Hong-y.n shao Jia-yu Pan Zi-Lin Huang Meng-Xuan Zuo Department of Minimally Invasive Interventional Therapy Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy State Key Laboratory of Oncology in South ChinaGuangzhou 510060Guangdong ProvinceChina Department of Minimally Invasive Interventional Therapy Guangdong Provincial Clinical Research Center for CancerGuangzhou 510060Guangdong ProvinceChina

BACKGROUnD Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating ***,large-scale studies on HAIC-based treatments and meta-analyses of first-line treatments for uHCC are *** To investigate better first-line treatment options for uHCC and to assess the safety and efficacy of HAIC combined with angiogenesis inhibitors,programmed cell death of protein 1(PD-1)and its ligand(PD-L1)blockers(triple therapy)under real-world *** Several electronic databases were searched to identify eligible randomized controlled trials for this ***-level pooled analyses of hazard ratios(HRs)and odds ratios(ORs)were *** was a retrospective single-center study involving 442 patients with uHCC who received triple therapy or angiogenesis inhibitors plus PD-1/PD-L1 blockades(AIPB)at Sun yat-sen University Cancer Center from January 2018 to April *** score matching(PSM)was performed to balance the bias between the *** Kaplan-Meier method and cox regression were used to analyse the survival data,and the log-rank test was used to compare the suvival time between the *** A total of 13 randomized controlled trials were *** alone and in combination with sorafenib were found to be effective treatments(P values for ORs:HAIC,0.95;for HRs:HAIC+sorafenib,0.04).After PSM,176 HCC patients were included in the *** triple therapy group(n=88)had a longer median overall survival than the AIPB group(n=88)(31.6 months vs 14.6 months,Pnd a greater incidence of adverse events(94.3%vs 75.4%,PnCLUSIOn This meta-analysis suggests that HAIC-based treatments are likely to be the best choice for *** findings confirm that triple therapy is more effective for uHCC patients than AIPB.

关键词： Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy Angiogenesis inhibitors Programmed cell death protein 1 Programmed death ligand 1

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In vitro bench testing using patient-specific 3D models for percutaneous pulmonary valve implantation with Venus P-valve

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Chinese Medical Journal 2024年第8期137卷 990-996页

作者： yu Han Zehua shao Zirui Sun y.n Han Hongdang Xu Shubo Song Xiangbin Pan Peter P.T.de Jaegere Taibing Fan Gejun Zhang Department of Structure Heart Disease Central China Fuwai Hospital of Zhengzhou UniversityZhengzhouHenan 451460China Children’s Heart Center Central China Fuwai Hospital of Zhengzhou UniversityZhengzhouHenan 451460China Department of Anesthesiology Central China Fuwai Hospital of Zhengzhou UniversityZhengzhouHenan 451460China Department of Structure Heart Disease Fuwai Hospital Chinese Academy of Medical SciencesBeijing 100037China Department of Cardiology Erasmus MCRotterdam 3015 GDNetherlands

Background:Due to the wide variety of morphology,size,and dynamics,selecting an optimal valve size and location poses great difficulty in percutaneous pulmonary valve implantation(PPVI).This study aimed to report our experience with in vitro bench testing using patient-specific three-dimensional(3D)-printed models for planning PPVI with the Venus ***:Patient-specific 3D soft models were generated using PolyJet printing with a compliant synthetic material in 15 patients scheduled to undergo PPVI between July 2018 and July 2020 in Central China Fuwai Hospital of Zhengzhou ***:3D model bench testing altered treatment strategy in all patients(100%).One patient was referred for surgery because testing revealed that even the largest Venus P-valve would not anchor *** the remaining 14 patients,valve size and/or implantation location was altered to avoid valve migration and/or compression coronary *** four patients,it was decided to change the point anchoring because of inverted cone-shaped right ventricular outflow tract(RVOT)(n=2)or risk of compression coronary artery.n=2).Concerning sizing,we found that an oversize of 2-5 mm *** of the valve was dictated by the flaring of the in-and outflow portion in the pulmonary *** was successful in all 14 patients(absence of valve migration,no coronary compression,and none-to-mild residual pulmonary regurgitation[PR]).The diameter of the Venus P-valve in the 3D simulation group was significantly smaller than that of the conventional planning group(36[2]vs.32[4],Z=-3.77,Pnclusions:In vitro testing indicated no need to oversize the Venus P-valve to the degree recommended by the balloon-sizing technique,as 2-5 mm sufficed.

关键词： Heart valve prosthesis implantation Percutaneous pulmonary valve intervention Pulmonary regurgitation bench testing 3D printing Venus P-valve

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