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Novel heating-and deformation-induced phase transitions and mechanical properties for multicomponent Zr_(50)M_(50),Zr_(50)(M,Ag)_(50)and Zr_(50)(M,Pd)_(50)(M=Fe,Co,Ni,Cu)amorphous alloys

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Journal of Materials Science & Technology 2022年第9期104卷 109-118页

作者： J.Ding A.Inoue F.l.Kong S.l.Zhu y.l.pu E.Shalaan A.A.Al-Ghamdi A.l.Greer School of Materials Science and Engineering Tianjin UniversityTianjin 300072China International Institute of Green Materials Josai International UniversityTogane 283-8555Japan Institute of Massive Amorphous Alloy Science China University of Mining TechnologyXuzhou 221116China Department of Physics King Abdulaziz UniversityJeddah 22254Saudi Arabia MISiS National University of Science and TechnologyMoscow 119049Russia School of Materials Science and Engineering Lanzhou Jiaotong UniversityLanzhou 730070China Department of Materials Science and Metallurgy University of CambridgeCambridge CB30FSUK

Multicomponent alloys of Zr_(50)M_(50),Zr_(50)(M,Ag)_(50)and Zr_(50)(M,Pd)_(50)(M=Fe,Co,Ni,Cu)can be melt-spun to obtain amorphous *** maximum thickness for fully amorphous ribbons varies with composition in the range 34-53μ*** contrast,fully amorphous ribbons are not obtainable for binary Zr_(50)Ni_(50)or ternary Zr_(50)(Ni,Cu)_(50)***-induced crystallization occurs through:two stages of amorphous[am]→[~(am')+B2]→[B2+B33]for Zr_(50)M_(50);and[am]→[am'+B2]→[B2+AgZr]for Zr_(50)(M,Ag)_(50);and a single stage of[am]→[B2]for Zr_(50)(M,Pd)_(50),while no B2 phase is formed for the binary and ternary Zr_(50)Q_(50)(Q=Ni or/and Cu)***-spun amorphous ribbons have good bending ***,Zr_(50)M_(50)ribbons in tension show 0.22-0.28%plastic elongation and work-hardening(the yield stress is~820 MPa,the fracture stress is~1200 MPa).When cold-rolled at room temperature to 30%reduction in thickness,Zr_(50)M_(50)ribbons show 10%increase in hardness,while retaining good bending ***-rolling induces precipitation of spheroidal B2 and irregular B33 particles,while deformation in tension induces B2,B33 and also plate-like monoclinic *** B2 and B33 particles form by polymorphic transformation,and include a high density of internal *** novel deformationinduced precipitation has not been recognized for any Zr_(50)Q_(50)binary or ternary *** new multicomponent systems are encouraging for future progress as structural amorphous alloys.

关键词： Multicomponent Microstructure Mechanical properties Phase transition Amorphous alloy

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A new horizon for neuroscience:terahertz biotechnology in brain research

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Neural Regeneration Research 2025年第2期20卷 309-325页

作者： Zhengping pu yu Wu Zhongjie Zhu Hongwei Zhao Donghong Cui Shanghai Key laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry Kangci Hospital of JiaxingTongxiangZhejiang ProvinceChina Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina Key laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of ScienceShanghaiChina National Facility for Protein Science in Shanghai Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina

Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain *** this article,we review the development of terahertz biotechnology and its applications in the field of *** evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin *** vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric *** the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic ***,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical *** review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.

关键词： biological effect brain neuron neuropsychiatry neuroscience non-thermal effect terahertz imaging terahertz radiation terahertz spectroscopy terahertz technology

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NOX4 exacerbates Parkinson's disease pathology by promoting neuronal ferroptosis and neuroinflammation

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Neural Regeneration Research 2025年第7期20卷 2038-2052页

作者： Zhihao lin Changzhou ying Xiaoli Si Naijia Xue yi liu Ran Zheng ying Chen Jiali pu Baorong Zhang Department of Neurology The Second Affiliated HospitalZhejiang University School of MedicineHangzhouZhejiang ProvinceChina

Parkinson's disease is primarily caused by the loss of dopaminergic neurons in the substantia nigra ***,a novel form of regulated cell death characterized by iron accumulation and lipid peroxidation,plays a vital role in the death of dopaminergic ***,the molecular mechanisms underlying ferroptosis in dopaminergic neurons have not yet been completely *** oxidase 4 is related to oxidative stress,however,whether it regulates dopaminergic neuronal ferroptosis remains *** aim of this study was to determine whether NADPH oxidase 4 is involved in dopaminergic neuronal ferroptosis,and if so,by what *** found that the transcriptional regulator activating transcription factor 3 increased NADPH oxidase 4 expression in dopaminergic neurons and astrocytes in an 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced Parkinson's disease *** oxidase 4 inhibition improved the behavioral impairments observed in the Parkinson's disease model animals and reduced the death of dopaminergic ***,NADPH oxidase 4 inhibition reduced lipid peroxidation and iron accumulation in the substantia nigra of the Parkinson's disease model ***,we found that NADPH oxidase 4 interacted with activated protein kinase Cαto prevent ferroptosis of dopaminergic ***,by lowering the astrocytic lipocalin-2 expression,NADPH oxidase 4 inhibition reduced 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine-induced *** findings demonstrate that NADPH oxidase 4 promotes ferroptosis of dopaminergic neurons and neuroinflammation,which contribute to dopaminergic neuron death,suggesting that NADPH oxidase 4 is a possible therapeutic target for Parkinson's disease.

关键词： dopaminergic neuron ferroptosis NADPH oxidase 4(NOX4) neuroinflammation Parkinson's disease

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Effects of aggregate size distribution and carbon nanotubes on the mechanical properties of cemented gangue backfill samples under true triaxial compression

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 311-324页

作者： Qian yin Fan Wen Zhigang Tao Hai pu Tianci Deng yaoyao Meng Qingbin Meng Hongwen Jing Bo Meng Jiangyu Wu State Key laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China State Key laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines Anhui University of Science and TechnologyHuainan 232001China State Key laboratory for Geomechanics&Deep Underground Engineering China University of Mining and Technology(Beijing)Beijing 100083China Key laboratory of Xinjiang Coal Resources Green Mining Ministry of EducationXinjiang Institute of EngineeringUrumqi 830023China

The mechanical behavior of cemented gangue backfill materials(CGBMs)is closely related to particle size distribution(PSD)of aggregates and properties of cementitious ***,the true triaxial compression tests,CT scanning,SEM,and EDS tests were conducted on cemented gangue backfill samples(CGBSs)with various carbon nanotube concentrations(P_(CNT))that satisfied fractal theory for the PSD of *** mechanical properties,energy dissipations,and failure mechanisms of the CGBSs under true triaxial compression were systematically *** results indicate that appropriate carbon nanotubes(CNTs)effectively enhance the mechanical properties and energy dissipations of CGBSs through micropore filling and microcrack bridging,and the optimal effect appears at P_(CNT)of 0.08wt%.Taking PSD fractal dimension(D)of 2.500 as an example,compared to that of CGBS without CNT,the peak strength(σ_(p)),axial peak strain(ε_(1,p)),elastic strain energy(Ue),and dissipated energy(U_(d))increased by 12.76%,29.60%,19.05%,and90.39%,***,excessive CNTs can reduce the mechanical properties of CGBSs due to CNT agglomeration,manifesting a decrease inρ_(p),ε_(1,p),and the volumetric strain increment(Δε_(v))when P_(CNT)increases from 0.08wt%to 0.12wt%.Moreover,the addition of CNTs improved the integrity of CGBS after macroscopic failure,and crack extension in CGBSs appeared in two modes:detour and pass through the ***σ_(p)and U_(d)firstly increase and then decrease with increasing D,and porosity shows the opposite ***ε_(1,p)andΔε_(v)are negatively correlated with D,and CGBS with D=2.150 has the maximum deformation parameters(ε_(1,p)=0.05079,Δε_(v)=0.01990)due to the frictional slip effect caused by coarse *** increasing D,the failure modes of CGBSs are sequentially manifested as oblique shear failure,"y-shaped"shear failure,and conjugate shear failure.

关键词： cemented gangue backfill materials particle size distribution true triaxial compression test carbon nanotubes mechanical properties failure modes

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Potassium ions and cyano group modified g-C3N4 for effective generation of H2O2 through two-electron oxygen reduction

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Science China Chemistry 2025年第1期 192-200页

作者： Dongying Wang Shulan pu yongmin Chen Ke lei yujie Duan linjiao Mao Xuhui Zeng Xi luo yuntao Zhang yuqin Dong Jin Zhong Zhang yan Sun School of Mechanical Engineering Chengdu University Department of Chemistry and Biochemistry University of California

Potassium ions （K+） doped graphitic carbon nitride （g-C3N4） was prepared by a thermal etching method using potassium hydroxide （KOH） as an ion *** transform infrared spectroscopy （FTIR） and X-ray photoelectron spectroscopy （XPS）results showed that the generation of the cyano group was detected while introducing K+.Under simulated sunlight irradiation,the sample with a K+doping amount of 10%showed the highest hydrogen peroxide （H2O2） generation rate of2,140.2μmol *** apparent quantum yield （AQy） at 400 nm and the solar-to-chemical conversion （SCC） are 4.35%and1.23%,respectively.K+acted as a bridge between g-C3N4layers,which enhanced charge transfer ***,the cyano group enhanced the adsorption capacity of protons （H+） and promoted the yield of *** catalyst exhibited excellent photocatalytic stability based on four-cycle *** addition,a mechanism study showed that superoxide radicals （·O2-）were the most important active species in the reaction *** production of H2O2was achieved through consecutive single-electron *** study deepens the understanding of the oxygen reduction reaction process and opens up a new venue for improving H2O2generation.

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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： lin-yan Huang yi-De Zhang Jie Chen Hai-Di Fan Wan Wang Bin Wang Ju-yun Ma Peng-Peng li Hai-Wei pu Xin-yian Guo Jian-Gang Shen Su-Hua Qi School of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina School of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

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Progress of crystalline carbon nitride in synthesis,atomic structure characterization and photocatalysis

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Nano Research 2025年第1期18卷 455-476页

作者： yueyang Tan Zhongyan Zhang yayun pu Zongzhao Sun limin Huang School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China Department of Chemistry Southern University of Science and TechnologyShenzhen 518055China School of Traffic and Environment Shenzhen Institute of Information TechnologyShenzhen 518172China College of Chemistry and Chemical Engineering Linyi UniversityLinyi 276000China School of Optoelectronic Engineering Chongqing University of Posts and TelecommunicationsChongqing 400065China

Crystalline carbon nitride(CCN)has emerged as a highly promising semiconductor photocatalyst with unique properties,such as enhanced charge migration rate,reduced carrier recombination probability,narrow band gap and improved light-harvesting efficiency,which are suitable for a wide range of applications in solar-to-chemical conversion,energy storage,therapeutic and environmental pollution *** the past few years,there has been an increasing number of reviews on CCN ***,most of these reviews mainly focus on synthesis methods,modification and applications,with less emphasis on the relationship between structures and properties,as well as on indepth exploration of the crystalline *** electronic instability of CCN presents challenges for conventional characterization techniques to directly and thoroughly investigate the relationship between its intrinsic atom structure and photocatalytic *** mini-review not only highlights the progress in CCN-based photocatalysts,with a focus on molten-salt synthesis(including solid-salt-induced crystallization),but also emphasizes the atomic structure characterization by specifically introducing the differential phase contrast(DPC)scanning transmission electron microscopy(STEM)technique,which is essential for enhancing our understanding of the crystal structure and photocatalytic mechanisms of ***,the review outlines the photocatalytic performance and puts forward potential challenges on CCN *** review will provide a clearer understanding of the relationship in developing precise customization strategies for CCN materials and ultimately explain the regularity and specificity of the enhanced performance in targeted photocatalytic systems.

关键词： crystalline carbon nitride synthesis characterization photocatalysis

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运动干预与细胞焦亡在骨关节炎中的作用

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中国组织工程研究 2025年第8期29卷 1667-1675页

作者：王秋月靳攀蒲锐长江大学教育与体育学院湖北省荆州市434023 长江大学医学部湖北省荆州市434023 长江大学运动人体科学实验室湖北省荆州市434023

背景:细胞焦亡参与软骨细胞外基质降解、滑膜炎症以及疼痛,在骨关节炎防治中发挥重要作用。此外,运动可通过抑制细胞焦亡调控骨关节炎的发生,已成为防治骨关节炎的研究热点。目的:总结细胞焦亡在骨关节炎中的调控作用,以及运动介导细胞... 详细信息

背景:细胞焦亡参与软骨细胞外基质降解、滑膜炎症以及疼痛,在骨关节炎防治中发挥重要作用。此外,运动可通过抑制细胞焦亡调控骨关节炎的发生,已成为防治骨关节炎的研究热点。目的:总结细胞焦亡在骨关节炎中的调控作用,以及运动介导细胞焦亡在改善骨关节炎中的机制。方法:以“pyroptosis,osteoarthritis,chondrocyte pyroptosis,synovial cell pyroptosis,exercise”和“细胞焦亡,骨关节炎,软骨细胞焦亡,滑膜细胞焦亡,运动”为关键词,检索pubMed与中国知网数据库1992-2024年间发表的相关文献,根据纳入及排除标准选择71篇文献进行综述。结果与结论:①骨关节炎是以软骨细胞外基质降解、滑膜炎症和软骨下骨重塑等为特点的慢性退行性关节疾病,易引起骨的器质性病变、疼痛并引发功能障碍。②细胞焦亡作为一种特殊的程序性死亡机制,其特征为细胞裂解死亡释放炎症因子引发强烈的炎症反应,与骨关节炎的发生发展关系密切。细胞焦亡可导致大量炎症因子释放,进而激活核因子κB转录,增加焦亡蛋白的产生,进而加剧骨关节炎的发生发展,因此细胞焦亡可作为骨关节炎防治的新方向。③运动可通过下调焦亡蛋白信号通路和抑制相关炎症因子表达等途径抑制软骨细胞和滑膜细胞的焦亡,从而在骨关节炎防治中发挥重要作用。有氧和无氧运动可通过抑制细胞焦亡的发生延缓骨关节炎的病理进程,中等强度的有氧运动通过抑制细胞焦亡信号通路改善骨关节炎的效果较好,无氧运动可通过提高肌肉质量进而对骨关节炎产生有益效应。

关键词：细胞焦亡骨关节炎运动运动调控信号通路综述

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PREDICTION OF MAXIMUM SCOUR DEPTH AROUND lARGE DIAMETER CylINDER UNDER THE EFFECTS OF BOTH WAVE AND CURRENT

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Journal of Hydrodynamics 2005年第1期17卷 74-79页

作者： lIlin-pu CUIli SchoolofCivilandHydraulicEngineering~DalianUniversityofTechnology Dalian116024china

Physical model tests were counducted to predict local scour and maximum scour depth around the large diameter cylinders located in the (sand) seabed under the action of both wave and current . According to the result of tests, an analysis was made on all the factors influencing the scour. The results shows that for the seabed with relative fine grains in shallow water (0.07l≤0.28),when the relative diameter D/l of the cylinder is within 0.3 0.7,the main effective scour factors around the cylinder in the seabed are diameter D of the cylinder, the wave height H, the wave length l, the velocity V c  of the current and the parameters related to the seabed soil texture. The main parameters influecing the maximum scour depth were analyzed, and the test data were syntherized, to obtain the formula predicting the scour depth around the large diameter cylinder under the of both wave and current.

关键词： offshore engineering the effects of both wave and current large diameter cylinder local scour

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A New Oviraptorid Dinosaur (Theropoda: Oviraptorosauria) from the late Cretaceous of Jiangxi Province, Southern China

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Acta Geologica Sinica(English Edition) 2013年第4期87卷 899-904页

作者： WEI Xuefang pu Hanyong XU li lIU Di lü Junchang Institute of Geology Chinese Academy of Geological Sciences Henan Geological Museum

A new oviraptorid dinosaur Jiangxisaurus ganzhouensis gen. et sp. nov., is erected based on a partial skeleton from the Upper Cretaceous Nanxiong Formation of Ganzhou City, Jiangxi Province. The new taxon differs from other oviraptorids in the weakly downturned rostrum of the lower jaw, much-elongated mandible with a height-to-length ratio being about 20% and the length ratio of radius to humerus of about 0.70. This species not only adds a new member to oviraptorid dinosaurs, but also provides more information about oviraptorid paleogeographical distribution in southern China.

关键词： Oviraptoridae Jiangxisaurus Nanxiong Formation Upper Cretaceous Ganzhou Basin,Jiangxi Province

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