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Conditioning of BPM pickup signals for operations of the Duke storage ring with a wide range of single-bunch current

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Chinese Physics C 2014年第10期38卷 82-91页

作者：徐卫李京祎黄森林 W.Z.wu H.Hao P.Wang y.k.wu National Synchrotron Radiation Laboratory (NSRL) University of Science and Technology of China Dept.of Physics Duke University and FEL labTriangle Universities Nuclear LaboratoryDurhamNC 27708-0308USA Institute of Heavy Ion Physics Peking University

The Duke storage ring is a dedicated driver for the storage ring based oscillator free-electron lasers（FELs）, and the High Intensity Gamma-ray Source（HIGS）. It is operated with a beam current ranging from about1 mA to 100 mA per bunch for various operations and accelerator physics studies. High performance operations of the FEL and γ-ray source require a stable electron beam orbit, which has been realized by the global orbit feedback system. As a critical part of the orbit feedback system, the electron beam position monitors（BPMs） are required to be able to precisely measure the electron beam orbit in a wide range of the single-bunch current. However, the high peak voltage of the BPM pickups associated with high single-bunch current degrades the performance of the BPM electronics, and can potentially damage the BPM electronics. A signal conditioning method using low pass filters is developed to reduce the peak voltage to protect the BPM electronics, and to make the BPMs capable of working with a wide range of single-bunch current. Simulations and electron beam based tests are performed. The results show that the Duke storage ring BPM system is capable of providing precise orbit measurements to ensure highly stable FEL and HIGS operations.

关键词： beam position monitor signal conditioning closed orbit feedback storage ring FEL

Enhanced mechanical performance of grain boundary precipitation-hardened high-entropy alloys via a phase transformation at grain boundaries

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Journal of Materials Science & Technology 2021年第27期86卷 271-284页

作者： y.L.Qi L.Zhao X.Sun H.X.Zong X.D.Ding F.Jiang H.L.Zhang y.k.wu L.He F.Liu S.B.Jin G.Sha J.Sun State key Laboratory for Mechanical Behavior of Materials Xi’an Jiaotong UniversityXi’an710049China Analytical&Testing Center Northwestern Polytechnical UniversityXi’an710072China School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China

Grain-boundary(GB)precipitation has a significant adverse effect on plasticity of alloys,which easily leads to catastrophic intergranular failure in safety-critical applications under high external ***,we report a novel strategy that uses the local stress concentration induced by GB precipitates as a driving force to trigger phase transformation of preset non-equiatomic high-entropy solid-solution phase at *** in situ deformation-induced phase transformation at GBs introduces a well-known effect:transformation-induced plasticity(TRIP),which enables an exceptional elongation to fracture(above 38%)at a high strength(above 1.5 GPa)in a GB precipitation-hardened high-entropy alloy(HEA).The present strategy in terms of"local stress concentration-induced phase transformations at GBs"may provide a fundamental approach by taking advantage of(rather than avoiding)the GB precipitation to gain a superior combination of high strength and high ductility in HEAs.

关键词： Non-equiatomic Grain-boundary precipitation High-entropy alloys Ductility Transformation-induced plasticity

Unique Genetic Features of Lean NAFLD: A Review of Mechanisms and Clinical Implications

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Journal of Clinical and Translational Hepatology 2024年第1期12卷 70-78页

作者： Jasmine Tidwell George y.wu Department of Medicine University of Connecticut Health CenterFarmingtonCTUSA Division of Gastroenterology-Hepatology University of Connecticut Health CenterFarmingtonCTUSA

Non-alcoholic fatty liver disease(NAFLD)affects 25%of the global *** 20%have a normal body mass index(BMI)and a variant known as lean *** typical NAFLD cases associated with obesity and diabetes,lean NAFLD causes liver disease by mechanisms not related to excess weight or insulin *** disorders are among the major factors in developing lean NAFLD,and genome-wide association studies have identified several genes associated with the *** review aims to increase awareness by describing the genetic markers linked to NAFLD and the defects involved in developing lean NAFLD.

关键词： Lean nonalcoholic fatty liver disease Palatine-like phospholipase domain-containing-3 Transmembrane 6 superfamily member 2 Familial hypobetalipoproteinemia Abetalipoproteinemia

Heritable Chronic Cholestatic Liver Diseases:A Review

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Journal of Clinical and Translational Hepatology 2024年第8期12卷 726-738页

Chronic cholestasis due to heritable causes is usually diagnosedin ***,many cases can present andsurvive into *** time course varies considerablydepending on the underlying *** data usuallyreveal elevated conjugated hyperbilirubinemia,alkalinephosphatase,and gamma-glutamyl *** be asymptomatic;however,when present,the typicalsymptoms are pruritus,jaundice,fatigue,and *** diagnostic methods and management requireddepend on the underlying *** development of genome-wide associated studies has allowed the identificationof specific genetic mutations related to the pathophysiologyof cholestatic liver *** aim of this review was tohighlight the genetics,clinical pathophysiology,presentation,diagnosis,and treatment of heritable etiologies of chroniccholestatic liver disease.

关键词： Chronic cholestasis Cholestatic liver disease Congenital hepatic fibrosis Caroli disease Caroli syndrome Alagille syndrome Biliary atresia

Focal Nodular Hyperplasia: A Comprehensive Review with a Particular Focus on Pathogenesis and Complications

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Journal of Clinical and Translational Hepatology 2024年第2期12卷 182-190页

作者： Jaimy Villavicencio kim George y.wu Division of Gastroenterology-Hepatology University of Connecticut Health CenterFarmingtonCTUSA

Focal nodular hyperplasia is a benign tumor of the liver that is often found incidentally with *** purpose of this review is to discuss the pathophysiology,rare complications that can occur due to these lesions,and management options.A literature review was performed on clinical trials and case reports involving focal nodular hyperplasia complications and management of these,as well as the proposed pathogenesis underlying these *** exposure to oral contraceptive pills and endogenous hormones have been thought to play a role in the development of these lesions,this has not been *** recently,they are thought to arise as a consequence of a vascular anomaly causing alterations in the expression of angiopoietin *** are rare,but previous cases have reported associated pain,rupture and compression of nearby structures(hepatic vein,stomach,biliary system).Resection of focal nodular hyperplasia is not usually ***,if there is associated pain with no other identifiable cause or presence of a large or growing lesion with risk of causing a complication,then surgical resection,radiofrequency ablation or arterial embolization should be considered.

关键词： Focal nodular hyperplasia Oral contraceptives Liver lesion

Stability and Generalization of Hypergraph Collaborative Networks

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Machine Intelligence Research 2024年第1期21卷 184-196页

作者： Michael k.Ng Hanrui wu Andy yip Institute of Data Science The University of Hong KongHong KongChina Department of Mathematics The University of Hong KongHong KongChina College of Information Science and Technology Jinan UniversityGuangzhou 510006China

Graph neural networks have been shown to be very effective in utilizing pairwise relationships across ***,there have been several successful proposals to generalize graph neural networks to hypergraph neural networks to exploit more com-plex *** particular,the hypergraph collaborative networks yield superior results compared to other hypergraph neural net-works for various semi-supervised learning *** collaborative network can provide high quality vertex embeddings and hyperedge embeddings together by formulating them as a joint optimization problem and by using their consistency in reconstructing the given *** this paper,we aim to establish the algorithmic stability of the core layer of the collaborative network and provide generaliz--ation *** analysis sheds light on the design of hypergraph filters in collaborative networks,for instance,how the data and hypergraph filters should be scaled to achieve uniform stability of the learning *** experimental results on real-world datasets are presented to illustrate the theory.

关键词： Hypergraphs vertices hyperedges collaborative networks graph convolutional neural networks(CNNs) stability generalization guarantees

Etiologies of Splenic Venous Hypertension:A Review

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Journal of Clinical and Translational Hepatology 2024年第6期12卷 594-606页

作者： Jasmine Tidwell Bianca Thakkar George y.wu Department of Medicine University of Connecticut Health CenterFarmingtonCTUSA Division of Gastroenterology-Hepatology University of Connecticut Health CenterFarmingtonCTUSA

Splenic venous hypertension or left-sided portal hypertension is a rare condition caused by an obstruction of the splenic ***,it presents with upper gastrointestinal bleeding in the absence of liver *** can be classified based on the mechanism of development of splenic vein hypertension:compression,stenosis,inflammation,thrombosis,and surgically decreased splenic venous *** is established by various imaging modalities and should be suspected in patients with gastric varices in the absence of esophageal varices,splenomegaly,or *** management and prognosis vary depending on the underlying etiology but generally involve reducing splenic venous *** aim of this review was to summarize the etiologies of splenic venous hypertension according to the mechanism of development.

关键词： Splenic venous hypertension Left-sided portal hypertension Sinistral portal hypertension Splenic vein thrombosis Gastric varices Hematemesis Upper gastrointestinal bleeding

Subnormal Serum Liver Enzyme Levels:A Review of Pathophysiology and Clinical Significance

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Journal of Clinical and Translational Hepatology 2024年第4期12卷 428-435页

作者： Elham M.youssef George y.wu Biochemistry Department National Research CenterCairoEgypt Department of Medicine Division of Gastroenterology-HepatologyUniversity of Connecticut Health CenterFarmingtonCTUSA

Subnormal levels of liver enzymes,below the lower limit of normal on local laboratory reports,can be useful *** instance,subnormal levels of aminotransferases can be observed in vitamin B6 deficiency and chronic kidney *** alkaline phosphatase levels may indicate the presence of hypophosphatasia,Wilson's disease,deficiencies of divalent ions,or *** levels of gamma glutamyl transferase may be seen in cases of acute intrahepatic cholestasis,the use of certain medications,and in bone ***,subnormal levels of 5'-nucleotidase have been reported in lead poisoning and nonspherocytic hemolytic *** aim of this review is to bring attention to the fact that subnormal levels of these enzymes should not be ignored as they may indicate pathological conditions and provide a means of early diagnosis.

关键词： Transaminases Vitamin B6 Celiac disease Renal insufficiency Hepatolenticular Degeneration Crohn disease Malnutrition Clofibrate Bone diseases Lead poisoning Anemia Hemolytic

Reactive destabilization and bidirectional catalyzation for reversible hydrogen storage of LiBH_(4) by novel waxberry-like nano-additive assembled from ultrafine Fe_(3)O_(4) particles

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Journal of Materials Science & Technology 2024年第6期173卷 63-71页

作者： S.Wang M.H.wu y.y.Zhu Z.L.Li y.X.yang y.Z.Li H.F.Liu M.X.Gao Department of Material Science Shenzhen MSU-BIT UniversityShenzhen 518172China State key Laboratory of Silicon and Advanced Semiconductor Materials&School of Materials Science and Engineering Zhejiang UniversityHangzhou 310027China Institute of Resources Utilization and Rare Earth Development State Key Laboratory of Rare Metals Separation and Comprehensive UtilizationGuangdong Provincial Key Laboratory of Rare Earth Development and ApplicationGuangdong Academy of SciencesGuangzhou 510650China Institute of Science and Technology for New Energy Xi’an Technological UniversityXi’an 710021China National Supercomputing Center in Shenzhen Shenzhen 518055China

LiBH_(4) containing 18.5 wt.%H_(2) is an attractive high-capacity hydrogen storage material,however,it suffers from high operation temperature and poor ***,a novel and low-cost bifunctional additive,waxberry-like Fe_(3)O_(4) secondary nanospheres assembled from ultrafine primary Fe_(3)O_(4) nanoparticles,is synthesized,which exhibits significant destabilization and bidirectional catalyzation towards(de)hydrogenation of LiBH_(4).With an optimized addition of 30 wt.% waxberry-like Fe_(3)O_(4),the system initiated dehydrogenation below 100℃ and released a total of 8.1 wt.%H_(2) to 400℃.After 10 cycles,a capacity retention of 70% was achieved,greatly superior to previously reported oxides-modified *** destabilizing and catalyzing mechanisms of waxberry-like Fe_(3)O_(4) on LiBH_(4) were systematically analyzed by phase and microstructural evolutions during dehydrogenation and hydrogenation cycling as well as density functional theory(DFT)*** present work provides new insights in developing advanced nano-additives with unique structural and multifunctional designs towards LiBH4 hydrogen storage.

关键词： LiBH_(4) Hydrogen storage Waxberry-like Fe_(3)O_(4) Destabilization Catalysis