检索结果-南通市图书馆

Caulerpa okamurae extract attenuates inflammatory interaction,regulates glucose metabolism and increases insulin sensitivity in 3T3-L1 adipocytes and RAW 264.7 macrophages

引用

journal of Integrative Medicine 2020年第3期18卷 253-264页

作者： Bikash Manandhar hyun jung Kim Dong young Rhyu Department of Oriental Medicine Resources and Institute of Korean Herbal Medicine Industry Mokpo National UniversityJeonnam 58554South Korea College of Pharmacy Mokpo National UniversityJeonnam 58554South Korea

Objective: To examine whether Caulerpa okamurae ethanolic extract(COE) could inhibit obesitymediated inflammation, improve glucose metabolism and increase insulin sensitivity, using in vitro cell models of RAW 264.7 macrophages and 3 T3-L1 ***: We cocultured 3 T3-L1 adipocytes in direct contact with lipopolysaccharide-stimulated RAW264.7 macrophages and induced insulin resistance in 3 T3-L1 adipocytes with tumor necrosis factor-a(TNF-a) in the presence or absence of 250 mg/m L of COE. We investigated various markers of inflammation, glucose regulation and insulin sensitivity in these models using Griess reagent to measure nitric oxide(NO) production, 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino]-2-deoxyglucose to measure glucose uptake, Western blot analysis to quantify protein expression and reverse transcriptasepolymerase chain reaction to evaluate m RNA ***: We found that COE(250 mg/m L) significantly inhibited the lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages by downregulating NO production, nitric oxide synthase 2 expression and nuclear translocation of nuclear factor-j B. COE also showed similar anti-inflammatory activity in coculture, along with decreased TNF-a, interleukin-6 and monocyte chemoattractant protein m RNA expression. In addition, COE also improved glucose uptake in coculture by upregulating glucose transporter-4(GLUT-4) and adiponectin and reducing serine phosphorylation of insulin receptor substrate-1(IRS1). In the TNF-a-induced insulin resistance model of 3 T3-L1 adipocytes, COE significantly improved both basal and insulin-stimulated glucose uptake, accompanied by phosphorylation of IRS1 at tyrosine 632, phospho-50 adenosine monophosphate-activated protein kinase a and glycogen synthase kinase-3 b(Ser9) as well as upregulation of ***: Together, these findings suggest that COE has potential to treat or prevent obesity-induced metabolic disorders.

关键词： Caulerpa okamurae RAW 264.7 macrophages 3T3-L1 adipocytes Coculture Metabolic disorder

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Unveiling the redox electrochemistry of 1D,urchin-like vanadium sulfide electrodes for high-performance hybrid supercapacitors

引用

journal of Energy Chemistry 2023年第4期79卷 569-580页

作者： K.Karuppasamy Dhanasekaran Vikraman Sajjad Hussain Balamurugan Thirumalraj P.Santhoshkumar Hemalatha Parangusan hyun-Chang Park jongwan jung hyun-Seok Kim Division of Electronics and Electrical Engineering Dongguk University-SeoulSeoul 04620Republic of Korea Department of Nanotechnology and Advanced Materials Engineering Sejong UniversitySeoul 05006Republic of Korea School of Materials Science&Engineering Kookmin UniversitySeoul 02707Republic of Korea Millimeter-Wave Innovation Technology Research Center(MINT) Dongguk University-SeoulSeoul 04620Republic of Korea Qatar University young Scientist Center(QUySC) Qatar UniversityP.O.Box 2713DohaQatar

Exploring novel versatile electrode materials with outstanding electrochemical performance is the key to the development of advanced energy conversion and storage *** this work,we aim to construct new-fangled one-dimensional(1D)quasi-layered patronite vanadium tetrasulfide(VS_(4))nanostructures by using different sulfur sources,namely thiourea,thioacetamide,and L-cysteine through an ethyleneaminetetraacetic-acid(EDTA)-mediated solvothermal *** as-prepared VS4exhibits several unique morphologies such as urchin,fluffy nanoflower,and polyhedron with appropriate surface *** the prepared nanostructures,the VS_(4)-1@NF nanostructure exhibited excellent electrochemical properties in 6 M KOH solution,and we explored its redox electrochemistry in *** asprepared VS_(4)-1@NF electrode exhibited battery-type redox characteristics with the highest capacity of280 C g^(-1)in a three-electrode ***,it offered a capacity of 123 F g^(-1)in a hybrid twoelectrode set-up at 1 A g^(-1)with the highest specific energy and specific power of 38.5 W h kg^(-1)and750 W kg^(-1),***,to ensure the practical applicability and real-world performance of the prepared hybrid AC@NF//VS_(4)-1@NF cell,we performed a cycling stability test with more than 5,000galvanostatic charge–discharge cycles at 2 A g^(-1),and the cell retained around 84.7%of its capacitance even after 5,000 cycles with a CE of 96.1%.

关键词： Patronite Redox electrochemistry Urchin VS_(4) 1D material Mesoporous

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acceleration of aging behavior and improvement of mechanical properties of extruded AZ80 alloy through(10–12) twinning

引用

journal of Magnesium and Alloys 2023年第2期11卷 671-683页

作者： hyun ji Kim ye jin Kim Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

The effects of pre-existing {10–12} extension twins on the precipitation behavior of an extruded AZ80 material during aging and on its mechanical properties after peak aging are investigated. The material containing {10–12} twins-which are formed by compression before aging(twinned material)-has a finer grain size and higher dislocation density than the extruded material. Although the peak hardnesses of the twinned and extruded materials are almost the same, the time to reach the peak hardness is considerably shorter in the former material than in the latter(4 h and 24 h, respectively). In the twinned material, the high dislocation density of the {10–12} twins promotes continuous precipitation, which results in the formation of numerous fine Mg17Al12precipitates within the twins in the early stage of *** formation of these continuous precipitates reduces the driving force for discontinuous precipitation, which consequently suppresses the formation and growth of coarse Mg17Al12precipitates at the grain boundaries. Despite its shorter peak-aging time, the 4 h-peak-aged twinned material shows higher tensile strength and elongation than the 24 h-peak-aged extruded material. These higher mechanical properties of the former material are attributed primarily to the presence of more abundant fine continuous precipitates, which are effective in strengthening the material, and less abundant coarse discontinuous precipitates, which can act as crack initiation sites. These results demonstrate that the introduction of {10–12} twins into wrought Mg–Al-based alloys can accelerate the Mg17Al12precipitation kinetics considerably and improve the strength and ductility of the peak-aged alloys simultaneously.

关键词： AZ80 alloy Twin Aging Precipitation Tensile properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of High-Performance Steel on the Tension Stiffening and Cracking Behavior of Reinforced Concrete (RC) Tension Ties

引用

journal of Iron and Steel Research International 2011年第S1期18卷 812-816页

作者： yun hyun-do Lee young-oh Ryu Seung-hyun Seo Soo-yeon Department of Architectural Engineering Chungnam National University Daejeon 305764 South Korea Department of Architectural Engineering Chungju National University Chungju South Korea

In construction industry, the application of high-performance reinforcement bar is required strongly. Unfortunately, not nearly enough research has been conducted on high-performance steel in comparison with high strength concrete. This paper describes the effect of high-performance steel as reinforcement steel bar on the tension response and cracking behavior of concrete and fiber-reinforced strain-hardening cement-based composite (SHCC) tension members. High-performance steel is characterized by higher strength in comparison to ASTM A615-06 Grade 60 steel. The tension stiffening effect on high-performance reinforcing bars embedded in cement-based composite prism is investigated experimentally. The variables in the study are types of cement-based composite (conventional concrete, synthetic fiber-reinforced cement composite), yielding strength of steel bars (400MPa and 600MPa), and types of loading (monotonic and repeated tension loading).

关键词： crack width tension stiffening fiber-reinforced strain-hardening cement-based composite tension

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ultra-low concentration of total organic carbon in ultrapure water using ion-exchange resin embedding silanized magnetic nanoparticles

引用

journal of Environmental Sciences 2020年第6期32卷 11-17页

作者： jung joon Lee jihyeon Park Bo-hyun Kim Sunjong Lee Department of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon 16419South Korea Korea Institute of Industrial Technology 89 Yangdaegiro-gilIpjang-myeonCheonan-si 31056South Korea

Regeneration of pure water is an important issue not only for the healthy life but also for the fine control of precise processes in various *** important issue in ultrahigh purified water is to reduce the amount of total organic carbon(TOC).Herein,we introduce a new approach to reduce the TOC using the surface silanized nanoparticles,in which the magnetic nanoparticles(mNPs)are silanized and then complexed with ion exchange resin(IER)*** Fe3O4 mNPs are surface modified by using high concentrated vinyltrimethoxysilane(VTMS)and then adhered on the surface of IER *** surface modified mNPs have a thick-shell of polysiloxane layer varying from 5 to 22 nm depending on the amount of VTMS used,which leads the significant increase of specific surface *** IER beads embedding VTMS-silanized mNPs achieves about 7μg/L of the TOC level in ultrapure water system,which is two orders less than 228μg/L of the feeding water and one order less than 96μg/L from the system using pristine IER *** result is mainly attributed to the polysiloxane layer forming broccoli-like surface structure and some part by the vinyl group of VTMS exposed to the amines in the water.

关键词： Total organic carbon Ultrapure water Magnetic nanoparticle Ion-exchange resin Hybrid structure

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Intraperitoneal chemotherapy for gastric cancer:A contemporary perspective

引用

Chinese journal of Cancer Research 2023年第1期35卷 15-18页

作者： So hyun Kang hyung-Ho Kim Department of Surgery Seoul National University Bundang HospitalSeongnam 13620Republic of Korea Department of Surgery Seoul National University College of MedicineSeoul 03080Republic of Korea

StageⅣgastric cancer and peritoneal metastasis Gastric cancer is one of the most common malignancies worldwide and is a leading cause of cancer-related deaths(1).Over the past few decades,advances in surgical techniq... 详细信息

关键词： chemotherapy gastric cancer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Comparative toxicity of silver nanoparticles and silver ions to Escherichia coli

引用

journal of Environmental Sciences 2018年第4期30卷 50-60页

作者： yoojin Choi hyun-A Kim Kyoung-Woong Kim Byung-Tae Lee Department of Chemical and Biomolecular Engineering (BK21 Plus Program) Korea Advanced Institute of Science and Technology (KAIST) School of Earth Sciences and Environmental Engineering Gwangju Institute of Science and Technology (GIST)

With the increase in silver（Ag）-based products in our lives, it is essential to test the potential toxicity of silver nanoparticles（Ag NPs） and silver ions（Ag ions） on living organisms under various conditions. Here, we investigated the toxicity of Ag NPs with Ag ions to Escherichia coli K-12 strain under various conditions. We observed that both Ag NPs and Ag ions display antibacterial activities, and that Ag ions had higher toxicity to E. coli K-12 strain than Ag NPs under the same concentrations. To understand the toxicity of Ag NPs at a cellular level, reactive oxygen species（ROS） enzymes were detected for use as antioxidant enzymatic biomarkers. We have also studied the toxicity of Ag NPs and Ag ions under various coexistence conditions including： fixed total concentration, with a varied the ratio of Ag NPs to Ag ions; fixed the Ag NPs concentration and then increased the Ag ions concentration; fixed Ag ions concentration and then increasing the Ag NPs *** to Ag NPs and Ag ions clearly had synergistic toxicity; however, decreased toxicity（for a fixed Ag NPs concentration of 5 mg/L, after increasing the Ag ions concentration） to E. coli K-12 strain. Ag NPs and Ag ions in the presence of L-cysteine accelerated the bacterial cell growth rate, thereby reducing the bioavailability of Ag ions released from Ag NPs under the single and coexistence conditions. Further works are needed to consider this potential for Ag NPs and Ag ions toxicity across a range of environmental *** Significance Statement： As silver nanoparticles（Ag NPs）-based products are being broadly used in commercial industries, an ecotoxicological understanding of the Ag NPs being released into the environment should be further considered. Here, we investigate the comparative toxicity of Ag NPs and silver ions（Ag ions） to Escherichia coli K-12 strain, a representative ecotoxicological bioreporter. This study showed that toxicities of Ag NPs and Ag ions to E. coli

关键词： Nanotoxicity Silver nanoparticles Silver ions Coexist condition Escherichia coli

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Polymer-based membranes for solvent-resistant nanofiltration:A review

引用

Chinese journal of Chemical Engineering 2017年第11期25卷 1653-1675页

作者： Slow Kee Lira Kunli Goh Tae-hyun Bae Rong Wang Singapore Membrane Technology Center Nanyang Environment and WaterResearch InstituteNanyang Technological UniversityI Cleantech Loop637141 SingaporeSingapore Nanyang Environment and Water Research Institute Interdisciplinary Graduate SchoolNanyang Technological University637141 SingaporeSingapore School of Chemical and Biomedical Engineenng Nanyang Technological University62 Nanyang Drive637459 SingaporeSingapore School of Civil and Environmental Engineering Nanyang Technological University50 NanyangAvenue639798 SingaporeSingapore

Separation of organic mixture is an inevitable process in most modern industrial processes. In the quest for a more sustainable and efficient separation, solvent-resistant nanofiltration(SRNF) has emerged as a promising answer. This is because SRNF is a membrane-based process which offers the key advantages of high efficacy and low energy intensity separation. In particular, polymer-based membranes can offer compelling opportunities for SRNF with unprecedented cost-effectiveness. As a result, intensive research efforts have been devoted into developing novel polymer-based membranes with solvent-resistant capacities as well as exploring potential applications in different types of industries. In this review, we aim to give an overview of the recent progress in the development of the state-of-the-art polymer-based membranes for SRNF in the first section. Emerging nanomaterials for mixed matrix and thin film nanocomposite membranes are also covered in this section. This is followed by a discussion on the current status of membrane engineering and SRNF membrane commercialization. In the third section, we highlight recent efforts in adopting SRNF for relevant industrial applications such as food, bio-refinery, petrochemical, fine chemical and pharmaceutical industries followed by separations of enantiomers in stereochemistry, homogeneous catalysis and ionic liquids. Finally, we offer a perspective and provide deeper insights to help shape future research direction in this very important field of SRNF.

关键词： Nanofiltration Solvent-resistant Polymeric membranes Nanomaterials Crosslinking Industrial applications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improving construction work zone safety using technology:A systematic review of applicable technologies

引用

journal of Traffic and Transportation Engineering(English Edition) 2020年第1期7卷 61-75页

作者： Chukwuma Nnaji john Gambatese hyun Woo Lee Fan Zhang Department of Civil Construction and Environmental EngineeringThe University of AlabamaTuscaloosaAL 35487USA School of Civil and Construction Engineering Oregon State UniversityCoruallisOR 97331USA Department of Construction Management University of WashingtonSeattleWA 98195USA School of Construction and Design University of Southern MississippiHattiesburgMS 39406USA

Once considered conventional,the construction industry is gradually increasing its reliance on innovations such as the application of technologies in safety *** the growing literature on technology applications in safety management and the varying opinions on the utility of applied technologies,a systematic review that streamlines findings from past studies is indispensable to construction *** a number of review studies are available in the building construction sector,the level of fragmentation and uniqueness within the construction industry necessitates a review study specifically targeting the heavy civil *** response,the present study applies a three-step approach to identify and review articles pertinent to the safety of highway construction work *** factors considered include the number of publications per year,publication locations,and technology *** addition,the present study proposes to broadly group work zone safety technologies(WZSTs)into three categories based on their primary purpose:speed reduction systems,intrusion prevention and warning systems,and human-machine-interaction detection *** findings include WZST research trends,application of smart work zone systems,and the potential relationship between WZSTs and *** paper ends with the identification of six additional research areas aimed at deepening the understanding of technology’s role in highway safety *** trend analysis and an in-depth discussion of each technology category alongside the identified research gaps will provide a substantial informative body of knowledge that both benefits current practitioners and directs researchers towards potential future studies.

关键词： Transportation Work zone Worker safety Technology application Safety technology Systematic review

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Acupoint catgut embedding for simple obesity in animal studies:a systematic review and Meta-analysis

引用

journal of Traditional Chinese Medicine 2023年第5期43卷 860-867页

作者： ZHAO Huiyan jUN Purumea LEE Chaewon HAN Chang-hyun Korean Convergence Medical Science University of Science and Technology(UST)School of Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea KM Science Research Division Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea KM Data Division Korea Institute of Oriental MedicineDaejeon 34054Republic of Korea St.johnsbury Academy jeju 304Global edu-roDaejeong-eupSeogwipo-si 63644Republic of Kore

OBjECTIVE:To assess the efficacy of acupoint catgut embedding(ACE)for simple obesity in preclinical animal ***:We searched the following 14 electronic databases:PubM ed,Cochrane Library,EMBASE,Oriental Medicine Advanced Searching Integrated System,KoreaMed,Korean Studies Information Service System,Science-on,Research Information Sharing Service,Korea Citation Index,Korea Traditional Knowledge Portal,China Network Knowledge Infrastructure Database,Wanfang Database,Chinese Science and Technology journal Database,and Chinese Biology Medicine Database,from inception to November 2021 without language *** assessment was performed according to the guidelines of Animal Research:Reporting of in vivo experiments;and Metaanalysis was performed using Reviewer Manager 5.4.1 ***:Twenty-four studies involving 813 animals were ***-analysis showed that ACE was beneficial for weight control[n=40,MD=-50.63,95%CI(-57.59,-43.67),Py of ACE was compared with that of manual acupuncture,electroacupuncture,or oilistat therapy,statistical difference was not observed between the two ***:This systematic review suggests that ACE may be efficacious in treating ***,the analyses highlighted the necessity to perform welldesigned,higher-quality experiments.

关键词： obesity acupoint catgut embedding animal study Meta-analysis systematic review

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：