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Normal epigenetic inheritance in mice conceived by in vitro fertilization and embryo transfer

journal of Zhejiang University-Science b(biomedicine & biotechnology) 2011年第10期12卷 796-804页

作者： Lei LI fang LE Li-ya wang Xiang-rong xu hang-ying LOU ying-ming ZhENG jiang-zhong ShENG he-feng hUANG fan jIN centre of Reproductive medicine Women＇s Hospital School of Medicine Zhejiang University Hangzhou 310006 China Department of Gynecologic Oncology Henan Cancer Hospital Zhengzhou 450003 China Department of cell biology School of Medicine Zhejiang University Hangzhou 310006 China

An association between assisted reproductive technology （ART） and neurobehavioral imprinting disorders has been reported in many studies, and it seems that ART may interfere with imprint reprogramming. however, it has never been explored whether epigenetic erros or imprinting disease susceptibility induced by ART can be inherited transgenerationally. hence, the aim of this study was to determine the effect of in vitro fertilization and embryo transfer （IVf-ET） on transgenerational inheritance in am inbred mouse model. mice derived from IVf-ET were outcrossed to wild-type c57bL/6j to obtain their female and male line f2 and f3 generations. Their behavior, morphology, histology, and DNA methylation status at several important differentially methylated regions （DmRs） were analyzed by morris water maze, hematoxylin and eosin （h＆E） staining, and bisulfite genomic sequencing. No significant differences in spatial learning or phenotypic abnormality were found in adults derived from IVf （f1） and female and male line f2 and f3 generations. A borderline trend of hypomethylation was found in h19 DmR cpG island 3 in the female line-derived f3 generation （0.40±0.118, P=0.086）. methylation status in h19/Igf2 DmR island 1, Igf2 DmR, KvDmR, and Snrpn DmR displayed normal patterns. methylation percentage did not differ significantly.f.om that of adults conceived naturally, and the expression of the genes they regulated was not disturbed. Transgenerational integrity, such as behavior, morphology, histology, and DNA methylation status, was maintained in these generations, which indicates that exposure of female germ cells to hormonel stimulation and gamete manipulation might not affect the individuals and their descendents.

关键词： Differentially methylated regions (DmRs), In vitro fertilization and embryo transfer (IVf-ET), centralnervous system (cNS), Neurobe havioral imprinting disorders, Transgenerational epigenetic inheritance

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Structural and functional basis for pan-coV fusion inh.b.tors against SARS-coV-2 and its variants with preclinical evaluation

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Signal Transduction and Targeted Therapy 2021年第8期6卷 2576-2585页

作者： Shuai Xia Qiaoshuai Lan yun Zhu chao wang Wei xu yutang Li Lijue wang fanke jiao jie Zhou chen hua Qian wang Xia cai yang Wu jie Gao huan Liu Ge Sun jan munch frank Kirchhoff Zhenghong yuan youhua Xie fei Sun Sh.b. jiang Lu Lu Key Laboratory of medical molecular Virology(mOE/Nhc/cAmS) School of Basic Medical Sciences and Biosafety Level 3 LaboratoryShanghai Institute of Infectious Disease and BiosecurityFudan UniversityShanghaiChina National Key Laboratory of biomacromolecules CAS Center for Excellence in BiomacromoleculesInstitute of BiophysicsChinese Academy of SciencesBeijingChina State Key Laboratory of Toxicology and medical countermeasures Beijing Institute of Pharmacology and ToxicologyBeijingChina china Institute for Radiation Protection TaiyuanShanxiChina lnstitute of molecular Virology Ulm University Medical CenterUlmGermany bioland Laboratory(Guangzhou Regenerative medicine and health Guangdong Laboratory) GuangzhouGuangdongChina

The cOVID-19 pandemic poses a global threat to public health and *** continuously emerging SARS-coV-2 variants present a major challenge to the development of antiviral agents and *** this study,we identified that EK1 and cholesterol-coupled derivative of EK1,EK1c4,as pan-coV fusion inh.b.tors,exh.b.t potent antiviral activity against SARS-coV-2 infection in both lung-and intestine-derived cell lines(calu-3 and caco2,respectively).They are also effective against infection of pseudotyped SARS-coV-2 variants b.1.1.7(Alpha)and b.l.1.248(Gamma)as well as those with mutations in S protein,including N417T,E484K,N501y,and D614G,which are common in South African and brazilian *** structure revealed that EK1 targets the hR1 domain in the SARS-coV-2 S protein to block virus-cell fusion and provide mechanistic insights into its broad and effective antiviral *** administration of EK1 peptides to hAcE2 transgenic mice significantly reduced viral titers in lung and intestinal ***1 showed good safety profiles in various animal models,supporting further clinical development of EK1-based pan-coV fusion inh.b.tors against SARS-coV-2 and its variants.

关键词： clinical lung intestine

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广泛耐药革兰阴性菌感染的实验诊断、抗菌治疗及医院感染控制:中国专家共识

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中国感染与化疗杂志 2017年第1期17卷 82-92页

作者：王明贵 X.Guan L.he b.hu j.hu X.huang G.Lai y.Li y.Liu y.Ni h.Qiu Z.Shao y.Shi m.wang R.wang D.Wu c.Xie y.xu f.yang K.yu y.yu j.Zhang c.Zhuo 复旦大学附属华山医院抗生素研究所上海200040 chinese XDR consensus Working Group

广泛耐药革兰阴性杆菌(XDR-GNb),是指除1~2类抗菌药物(主要指多黏菌素和替加环素)外,几乎对所有类别抗菌药物均不敏感的革兰阴性杆菌。XDR-GNb常见于肠杆菌科细菌、鲍曼不动杆菌、铜绿假单胞菌和嗜麦芽窄食单胞菌等。近年来,中国XDR-GN... 详细信息

广泛耐药革兰阴性杆菌(XDR-GNb),是指除1~2类抗菌药物(主要指多黏菌素和替加环素)外,几乎对所有类别抗菌药物均不敏感的革兰阴性杆菌。XDR-GNb常见于肠杆菌科细菌、鲍曼不动杆菌、铜绿假单胞菌和嗜麦芽窄食单胞菌等。近年来,中国XDR-GNb的发生率呈不断上升趋势,由于缺乏有效的治疗药物,XDR-GNb感染成为公共卫生安全的一大威胁。我国有关感染的临床、微生物学及临床药理学专家们就XDR-GNb感染的实验室诊断、临床诊疗和医院感染控制等问题深入讨论,形成此共识。其中细菌药敏试验的抗菌药物品种及结果判定标准遵循美国临床和实验室标准化协会(cLSI)、欧洲抗菌药物敏感性试验委员会(EUcAST)或美国食品与药物监督管理局(fDA)的指南。研究提示长疗程使用广谱抗菌药物是引发XDR-GNb感染最重要的危险因素。根据现有的临床研究和实验室数据,共识提供治疗各种XDRGNb感染的联合用药推荐方案,其中常用的抗菌药物有替加环素、多黏菌素、碳青霉烯类、氨基糖苷类和磷霉素等。同时建议实行严格的感染控制措施,包括手卫生、接触隔离、主动筛查、环境消毒、去定植和抗菌药物应用管理等遏制XDRGNb感染的传播。

关键词：广泛耐药肠杆菌科细菌鲍曼不动杆菌铜绿假单胞菌嗜麦芽窄食单胞菌抗菌治疗

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methods for a blind analysis of isobar data collected by the STAR collaboration

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Nuclear Science and Techniques 2021年第5期32卷 43-50页

作者： j.Adam L.Adamczyk j.R.Adams j.K.Adkins G.Agakishiev m.m.Aggarwal Z.Ahammed I.Alekseev D.m.Anderson A.Aparin E.c.Aschenauer m.U.Ashraf f.G.Atetalla A.Attri G.S.Averichev V.bairathi K.barish A.behera R.bellwied A.bhasin j.bielcik j.bielcikova L.c.b.and I.G.bordyuzhin j.D.brandenburg A.V.brandin j.butterworth h.caines m.calderon de la barca Sanchez D.c.b.a I.chakaberia P.chaloupka b.K.chan f-h.chang Z.chang N.chankova-bunzarova A.chatterjee D.chen j.chen j.h.chen X.chen Z.chen j.cheng m.cherney m.chevalier S.choudhury W.christie X.chu h.j.crawford m.csanad m.Daugherity T.G.Dedovich I.m.Deppner A.A.Derevschikov L.Didenko X.Dong j.L.Drachenberg j.c.Dunlop T.Edmonds N.Elsey j.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.fatemi S.fazio P.federic j.fedorisin c.j.feng y.f.ng P.filip E.finch y.f.syak A.francisco L.fulek c.A.Gagliardi T.Galatyuk f.Geurts A.Gibson K.Gopal X.Gou D.Grosnick W.Guryn A.I.hamad A.hamed S.harabasz j.W.harris S.he W.he X.h.he y.he S.heppelmann S.heppelmann N.herrmann E.hoffman L.holub y.hong S.horvat y.hu h.Z.huang S.L.huang T.huang X.huang T.j.humanic P.huo G.Igo D.Isenhower W.W.jac.b. c.jena A.jentsch y.ji j.jia K.jiang S.jowzaee X.ju E.G.judd S.Kabana m.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder h.W.Ke D.Keane A.Kechechyan m.Kelsey y.V.Khyzhniak D.P.Kikoła c.Kim b.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev m.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli j.h.Kwasizur R.Lacey S.Lan j.m.Landgraf j.Lauret A.Lebedev R.Lednicky j.h.Lee y.h.Leung c.Li c.Li W.Li W.Li X.Li y.Li y.Liang R.Licenik T.Lin y.Lin m.A.Lisa f.Liu h.Liu P.Liu P.Liu T.Liu X.Liu y.Liu Z.Liu T.Ljubicic W.j.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.ma L.ma R.ma y.G.ma N.magdy R.majka D.mallick S.margetis c.markert h.S.matis j.A.mazer N.G.minaev S.mioduszewski b.mohanty I.mooney Z.moravcova D.A.morozov m.Nagy j.D.Nam md.Nasim K.Nayak D.Neff j.m.Nelson D.b.Nemes m.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonak christian University AbileneTX 796992 AGh University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRc"Kurchatov Institute" MoscowRussia 117218 Argonne National Laboratory ArgonneIL 60439 American University of cairo New CairoNew Cairo 11835Egypt brookhaven National Laboratory UptonNY 11973 University of california BerkeleyCA 94720 University of california DavisCA 95616 University of california Los AngelesCA 90095 University of california RiversideCA 92521 central china Normal University Wuhan 430079 University of Illinois at chicago ChicagoIL 60607 creighton University OmahaNE 68178 czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universitat Darmstadt Darmstadt 64289Germany ELTE Eotvos Lorand University Budapest 1117Hungary frankfurt Institute for Advanced Studies fIAS Frankfurt 60438Germany fudan University Shanghai 200433 University of heidelberg 69120 HeidelbergGermany University of houston HoustonTX 77204 huzhou University Huzhou 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIN 47408 Institute of modern Physics Chinese Academy of SciencesLanzhou 730000 University of j.m.u Jammu 180001India joint Institute for Nuclear Research DubnaRussia 141980 Kent State University KentOH 44242 University of Kentucky LexingtonKY 40506-0055 Lawrence berkeley National Laboratory BerkeleyCA 94720 Lehigh University BethlehemPA 18015 max-Planck-Institut fur Physik 80805 MunichGermany michigan State University East LansingMI 48824 National Research Nuclear University mEPhI MoscowRussia 115409 National Institute of Science Education and Research HBNIJatni 752050India National cheng Kung University Tainan 70101 Nuclear Physics Institute of the cAS Rez 25068Czech Republic Ohio State University

In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of *** isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)*** order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis *** are initially provided a"reference sample"of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run *** tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking *** this sample,species-specific information is disguised,but individual output files contain data from a single isobar *** run-by-run corrections and code alteration subsequent to these corrections are allowed at this *** these modifications,the"frozen"code is passed over the fully un-blind data,completing the blind *** a check of the feasibility of the blind analysis procedure,analysts completed a"mock data challenge,"analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in *** Au+Au data were prepared in the same manner intended for the isobar blind *** details of the blind analysis procedure and results from the mock data challenge are presented.

关键词： blind analysis chiral magnetic effect heavy-ion collisions

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SyK-mediated epithelial cell state is associated with response to c-met inh.b.tors in c-met-overexpressing lung cancer

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Signal Transduction and Targeted Therapy 2023年第6期8卷 3098-3110页

作者： ji Zhou xu-chao Zhang Shan xue mengdi Dai yueliang wang Xia Peng jianjiao chen Xinyi wang yanyan Shen hui Qin bi chen yu Zheng Xiwen Gao Zuoquan Xie jian Ding handong jiang yi-Long Wu meiyu Geng jing Ai Division of Antitumor Pharmacology State Key Laboratory of Drug ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai201203China University of chinese Academy of Sciences No.19A Yuquan RoadBeijing100049China Guangdong Provincial Key Laboratory of Translational medicine in Lung cancer Guangdong Lung Cancer InstituteGuangdong Provincial People’s Hospitaland Guangdong Academy of Medical SciencesSchool of MedicineSouth China University of TechnologyGuangzhou510080China Department of Respiratory medicine Ren Ji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200127China Department of Neurobiology Brain InstituteUniversity of PittsburghPittsburgh15213USA Department of Respiratory medicine Affiliated Hospital of Xuzhou Medical UniversityXuzhou221000China Department of Respiratory medicine Minhang HospitalFudan UniversityShanghai201199China School of Pharmaceutical Science and Technology Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou310024P.R.China

Genomic mET amplification and exon 14 skipping are currently clinically recognized biomarkers for stratifying subsets of non-small cell lung cancer(NScLc)patients according to the predicted response to c-met inh.b.tors(c-metis),yet the overall clinical benefit of this strategy is quite ***,c-met protein overexpression,which occurs in approximately 20–25%of NScLc patients,has not yet been clearly defined as a clinically useful *** optimized strategy.f.r accurately classifying patients with c-met overexpression for decision-making regarding c-meti treatment is ***,we found that SyK regulates the plasticity of cells in an epithelial state and is associated with their sensitivity to c-metis both in vitro and in vivo in PDX models with c-met overexpression regardless of mET gene ***,TGf-β1 treatment resulted in SyK transcriptional downregulation,increased Sp1-mediated transcription of fRA1,and restored the mesenchymal state,which conferred resistance to ***,a subpopulation of NScLc patients with c-met overexpression coupled with SyK overexpression exh.b.ted a high response rate of 73.3%and longer progression-free survival with c-meti treatment than other *** negativity coupled with TGf-β1 positivity conferred de novo and acquired *** summary,SyK regulates cell plasticity toward a therapy-sensitive epithelial cell ***,our findings showed that SyK overexpression can aid in precisely stratifying NScLc patients with c-met overexpression regardless of mET alterations and expand the population predicted to benefit from c-met-targeted therapy.

关键词： SyK alterations state

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measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √sNN=200 GeV

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chinese Physics c 2020年第10期44卷 59-67页

作者： L.Adamczyk j.R.Adams j.K.Adkins G.Agakishiev m.m.Aggarwal Z.Ahammed I.Alekseev D.m.Anderson A.Aparin E.c.Aschenauer m.U.Ashraf f.G.Atetalla A.Attri G.S.Averichev V.bairathi K.barish A.behera R.bellwied A.bhasin j.bielcik j.bielcikova L.c.b.and I.G.bordyuzhin j.D.brandenburg A.V.brandin j.butterworth h.caines m.calderón de la barca Sánchez D.c.b.a I.chakaberia P.chaloupka b.K.chan f-h.chang Z.chang N.chankova-bunzarova A.chatterjee D.chen j.h.chen X.chen Z.chen j.cheng m.cherney m.chevalier S.choudhury W.christie X.chu h.j.crawford m.csanád m.Daugherity T.G.Dedovich I.m.Deppner A.A.Derevschikov L.Didenko X.Dong j.L.Drachenberg j.c.Dunlop T.Edmonds N.Elsey j.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.fatemi S.fazio P.federic j.fedorisin c.j.feng y.f.ng P.filip E.finch y.f.syak A.francisco L.fulek c.A.Gagliardi T.Galatyuk f.Geurts A.Gibson K.Gopal D.Grosnick W.Guryn A.I.hamad A.hamed S.harabasz j.W.harris S.he W.he X.h.he S.heppelmann S.heppelmann N.herrmann E.hoffman L.holub y.hong S.horvat y.hu h.Z.huang S.L.huang T.huang X.huang T.j.humanic P.huo G.Igo D.Isenhower W.W.jac.b. c.jena A.jentsch y.jI j.jia K.jiang S.jowzaee X.ju E.G.judd S.Kabana m.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder h.W.Ke D.Keane A.Kechechyan m.Kelsey y.V.Khyzhniak D.P.Kikoła c.Kim b.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev m.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli j.h.Kwasizur R.Lacey S.Lan j.m.Landgraf j.Lauret A.Lebedev R.Lednicky j.h.Lee y.h.Leung c.Li W.Li W.Li X.Li y.Li y.Liang R.Licenik T.Lin y.Lin m.A.Lisa f.Liu h.Liu P.Liu P.Liu T.Liu X.Liu y.Liu Z.Liu T.Ljubicic W.j.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.ma L.ma R.ma y.G.ma N.magdy R.majka D.mallick S.margetis c.markert h.S.matis j.A.mazer N.G.minaev S.mioduszewski b.mohanty I.mooney Z.moravcova D.A.morozov m.Nagy j.D.Nam Nasim md K.Nayak D.Neff j.m.Nelson D.b.Nemes m.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa Abilene christian University AbileneTexas 79699 AGh University of Science and Technology FPACSCracow 30-059Poland Alikhanov Institute for Theoretical and Experimental Physics NRc"Kurchatov Institute" Moscow 117218Russia Argonne National Laboratory ArgonneIllinois 60439 American University of cairo New Cairo 11835New CairoEgypt brookhaven National Laboratory UptonNew York 11973 University of california BerkeleyCalifornia 94720 University of california DavisCalifornia 95616 University of california Los AngelesCalifornia 90095 University of california RiversideCalifornia 92521 central china Normal University WuhanHubei 430079 University of Illinois at chicago ChicagoIllinois 60607 creighton University OmahaNebraska 68178 czech Technical University in Prague FNSPEPrague 11519Czech Republic Technische Universität Darmstadt Darmstadt 64289Germany ELTE Eötvös Loránd University BudapestHungary H-1117 frankfurt Institute for Advanced Studies fIAS Frankfurt 60438Germany fudan University Shanghai 200433 University of heidelberg Heidelberg 69120Germany University of houston HoustonTexas 77204 huzhou University HuzhouZhejiang 313000 Indian Institute of Science Education and Research(IISER) Berhampur 760010India Indian Institute of Science Education and Research(IISER)Tirupati Tirupati 517507India Indian Institute Technology PatnaBihar 801106India Indiana University BloomingtonIndiana 47408 Institute of modern Physics Chinese Academy of SciencesLanzhouGansu 730000 University of j.m.u Jammu 180001India joint Institute for Nuclear Research Dubna 141980Russia Kent State University KentOhio 44242 University of Kentucky LexingtonKentucky 40506-0055 Lawrence berkeley National Laboratory BerkeleyCalifornia 94720 Lehigh University BethlehemPennsylvania 18015 max-Planck-Institut für Physik Munich 80805Germany michigan State University East LansingMichigan 48824 National Research Nuclear University mEPhI Moscow 115409Russia National Institute of Science Education and Research HBNIJatni 752050Indi

high transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion *** of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic *** report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR *** correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5c,are consistent with Gaussians,and their widths increase with *** results indicate jet broadening in the medium created in central heavy-ion collisions.

关键词： di-hadron correlations jet heavy-ion

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measurement of integrated luminosities at bESⅢ for data samples at center-of-mass energies between 4.0 and 4.6 GeV

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chinese Physics c 2022年第11期46卷 53-63页

作者： m.Ablikim m.N.Achasov P.Adlarson S.Ahmed m.Albrecht R.Aliberti A.Amoroso m.R.An Q.An X.h.b.i y.bai O.bakina R.baldini ferroli I.balossino y.ban V.batozskaya D.becker K.begzsuren N.berger m.bertani D.bettoni f.bianchi j.bloms A.bortone I.boyko R.A.briere A.brueggemann h.cai X.cai A.calcaterra G.f.cao N.cao S.A.cetin j.f.chang W.L.chang G.chelkov c.chen G.chen h.S.chen m.L.chen S.j.chen T.chen X.R.chen X.T.chen y.b.chen Z.j.chen W.S.cheng X.chu G.c.b.netto f.cossio j.j.cui h.L.Dai j.P.Dai A.Dbeyssi R.Ede boer D.Dedovich Z.y.Deng A.Denig I.Denysenko m.Destefanis f.De mori y.Ding j.Dong L.y.Dong m.y.Dong X.Dong S.X.Du P.Egorov y.L.fan j.fang S.S.fang W.X.fang y.f.ng R.farinelli L.fava f.feldbauer G.felici c.Q.feng j.h.feng K fischer m.fritsch c.fritzsch c.D.fu h.Gao y.N.Gao yang Gao S.Garbolino I.Garzia P.T.Ge c.Geng E.m.Gersabeck A Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco m.h.Gu c.y Guan A.Q.Guo L.b.Guo R.P.Guo y.P.Guo A.Guskov T.T.han W.y.han X.Q.hao f.A.harris K.K.he K.L.he f.h.heinsius c.h.heinz y.K.heng c.herold m.himmelreich T.holtmann G.y.hou y.R.hou Z.L.hou h.m.hu j.f.hu T.hu y.hu G.S.huang K.X.huang L.Q.huang L.Q.huang X.T.huang y.P.huang Z.huang T.hussain N husken W.Imoehl m.Irshad j.jackson S.jaeger S.janchiv Q.ji Q.P.ji X.b.ji X.L.ji y.y.ji Z.K.jia h.b.jiang S.S.jiang X.S.jiang y.jiang j.b.jiao Z.jiao S.jin y.jin m.Q.jing T.johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert m.Kavatsyuk b.c.Ke I.K.Keshk A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.b.Kolcu b.Kopf m.Kuemmel m.Kuessner A.Kupsc W.Kuhn j.j.Lane j.S.Lange P.Larin A.Lavania L.Lavezzi Z.h.Lei h.Leithoff m.Lellmann T.Lenz c.Li c.Li c.h.Li cheng Li D.m.Li f.Li G.Li h.Li h.Li h.b.Li h.j.Li h.N.Li j.Q.Li j.S.Li j.W.Li Ke Li L.j Li L.K.Li Lei Li m.h.Li P.R.Li S.X.Li S.y.Li T.Li W.D.Li W.G.Li X.h.Li X.L.Li Xiaoyu Li Z.y.Li h.Liang h.Liang h.Liang y.f.Liang y.T.Liang G.R.Liao L.Z.Liao j.Libby A.Limphirat c.X.Lin D.X.Lin T.Lin b.j.Liu c.X.Liu D.Liu f.h.Liu fang Liu feng Liu G.m.Liu h.Liu h.m.Liu huanhuan Liu huihui Liu j.b.Liu j.L.Liu j.y.Liu K.L Institute of high Energy Physics Beijing 100049China beihang University Beijing 100191China beijing Institute of Petrochemical Technology Beijing 102617China bochum Ruhr-University D-44780 BochumGermany carnegie mellon University PittsburghPennsylvania 15213USA central china Normal University Wuhan 430079China china center of Advanced Science and Technology Beijing 100190China cOmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan fudan University Shanghai 200433China G.I.budker Institute of Nuclear Physics Sb RAS(bINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Staudinger Weg 18D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China henan University of Technology Zhengzhou 450001China huangshan college Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INfN Laboratori Nazionali di frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INfN Laboratori Nazionali di frascati INFN Sezione di PerugiaI-06100PerugiaItaly INfN Laboratori Nazionali di frascati University of PerugiaI-06100PerugiaItaly INfN Sezione di ferrara INFN Sezione di FerraraI-44122FerraraItaly INfN Sezione di ferrara University of FerraraI-44122FerraraItaly Institute of modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia jilin University Changchun 130012China johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia justus-Liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16

The integrated luminosities of data samples collected in the bESⅢ experiment in 2016-2017 at centerof-mass energies between 4.19 and 4.28 GeV are measured with a precision better than 1% by analyzing large-angle bh.b.a scattering *** integrated luminosities of old datasets collected in 2010-2014 are updated by considering corrections related to detector performance,offsetting the effect of newly discovered readout errors in the electromagnetic calorimeter,which can haphazardly occur.

关键词： integrated luminosity e^(+)e^(-)annihilation bh.b.a scattering

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Effect of corn particle size on mucosal morphology and digesta ph of the gastrointestinal tract in growing goats

Effect of corn particle size on mucosal morphology and diges...

引用

低碳经济与高效养殖——第六次全国饲料营养学术研讨会暨动物营养学分会成立三十周年大会

作者： m.xu~a,y.Dong~b,S.Du~a,y.S.hao~c,y.h.wang~d,f.N.wang~a,j.h.yao~(a*) (a Northwest A&f University,Shaanxi,yangling 712100,PRc.b.yangling Vocational and Technical college,Shaanxi, yangling 712100,PRc c h.b.i Agriculture University,h.b.i,Dingzhou,073000,PRc d xuzhou Normal University, jiangsu,xuzhou 221116,PRc)

A slaughter experiment was conducted to determine the effect of corn particle size on mucosal morphology and digesta ph in the gastrointestinal tract of *** Guanzhong wether goats aged 9 months(23.5±0.3 kg) were randomly.f.d diets containing 55%corn silage and 28%finely cracked,coarsely cracked or whole corn. After a 35 d feeding period,goats were slaughtered to obtain digesta samples for ph determination,andA slaughter experiment was conducted to determine the effect of corn particle size on mucosal morphology and digesta ph in the gastrointestinal tract of *** Guanzhong wether goats aged 9 months(23.5±0.3 kg) were randomly.f.d diets containing 55%corn silage and 28%finely cracked,coarsely cracked or whole corn. After a 35 d feeding period,goats were slaughtered to obtain digesta samples for ph determination,and

关键词： corn particle size mucosal morphology digesta ph goat

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Studies of laser-plasma interaction physics with low-density targets for direct-drive inertial confinement fusion on the Shenguang III prototype

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matter and Radiation at Extremes 2021年第2期6卷 54-66页

作者： V.T.Tikhonchuk T.Gong N.jourdain O.Renner f.P.condamine K.Q.Pan W.Nazarov L.hudec j.Limpouch R.Liska m.Krus f.wang D.yang S.W.Li Z.c.Li Z.y.Guan y.G.Liu T.xu X.S.Peng X.m.Liu y.L.Li j.Li T.m.Song j.m.yang S.E.jiang b.h.Zhang W.y.huo G.Ren y.h.chen W.Zheng y.K.Ding K.Lan S.Weber ELI-beamlines Institute of PhysicsCzech Academy of Sciences25241 Dolni BrezanyCzech Republic centre Lasers Intenses et Applications University of Bordeaux-CNRS-CEA33405 TalenceFrance Laser fusion Research center China Academy of Engineering PhysicsMianyang 621900China Institute of Plasma Physics Czech Academy of Sciences18200 PragueCzech Republic Independent foam Target Supplier CarnoustieDD76DPUnited Kingdom faculty of Nuclear Sciences and Physical Engineering Czech Technical University in Prague11519 PragueCzech Republic Institute of Applied Physics and computational mathematics Beijing 100088China center for Applied Physics and Technology Peking UniversityBeijing 100871China School of Science Xi’an Jiaotong UniversityXi’an 710049China

The physics of laser-plasma interaction is studied on the Shenguang III prototype laser facility under conditions relevant to inertial confinement fusion designs.A sub-millimeter-size underdense hot plasma is created by ionization of a low-density plastic foam by.f.ur high-energy(3.2 kj)laser *** interaction beam is fired with a delay permitting evaluation of the excitation of parametric instabilities at different stages of plasma *** diagnostics are used for plasma characterization,scattered radiation,and accelerated *** experimental results are analyzed with radiation hydrodynamic simulations that take account of foam ionization and *** measured level of stimulated Raman scattering is almost one order of magnitude larger than that measured in experiments with gasbags and hohlraums on the same installation,possibly because of a greater plasma *** amplification is achieved in high-intensity speckles,indicating the importance of implementing laser temporal smoothing techniques with a large bandwidth for controlling laser propagation and absorption.

关键词： density. interaction scattered

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Observation of e^+e^-→D_s^+■^((*)0)K^- and study of the P-wave D_s mesons

引用

chinese Physics c 2019年第3期43卷 5-16页

作者： m.Ablikim m.N.Achasov S.Ahmed m.Albrecht m.Alekseev A.Amoroso f.f.An Q.An y.bai O.bakina R.baldini ferroli y.ban K.begzsuren D.W.bennett j.V.bennett N.berger m.bertani D.bettoni f.bianchi I.boyko R.A.briere h.cai X.cai A.calcaterra G.f.cao S.A.cetin j.chai j.f.chang W.L.chang G.chelkov G.chen h.S.chen j.c.chen m.L.chen S.j.chen y.b.chen W.S.cheng G.c.b.netto f.cossio h.L.Dai j.P.Dai A.Dbeyssi D.Dedovich Z.y.Deng A.Denig I.Denysenko m.Destefanis f.De mori y.Ding c.Dong j.Dong L.y.Dong m.y.Dong Z.L.Dou S.X.Du j.Z.fan j.fang S.S.fang y.f.ng R.farinelli L.fava f.feldbauer G.felici c.Q.feng m.fritsch c.D.fu y.f. Q.Gao X.L.Gao y.N.Gao y.G.Gao Z.Gao b.Garillon I.Garzia A.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl m.Greco L.m.Gu m.h.Gu S.Gu y.T.Gu A.Q.Guo L.b.Guo R.P.Guo y.P.Guo A.Guskov Z.haddadi S.han X.Q.hao f.A.harris K.L.he f.h.heinsius T.held y.K.heng Z.L.hou h.m.hu j.f.hu T.hu y.hu G.S.huang j.S.huang X.T.huang X.Z.huang Z.L.huang N.huesken T.hussain W.Ikegami Andersson W.Imoehl m.Irshad Q.ji Q.P.ji X.b.ji X.L.ji h.L.jiang X.S.jiang X.y.jiang j.b.jiao Z.jiao D.P.jin S.jin y.jin T.johansson N.Kalantar-Nayestanaki X.S.Kang m.Kavatsyuk b.c.Ke I.K.Keshk T.Khan A.Khoukaz P.Kiese R.Kiuchi R.Kliemt L.Koch O.b.Kolcu b.Kopf m.Kuemmel m.Kuessner A.Kupsc m.Kurth W.Kühn j.S.Lange P.Larin L.Lavezzi h.Leithoff c.Li cheng Li D.m.Li f.Li f.y.Li G.Li h.b.Li h.j.Li j.c.Li j.W.Li Ke Li L.K.Li Lei Li P.L.Li P.R.Li Q.y.Li W.D.Li W.G.Li X.L.Li X.N.Li X.Q.Li Z.b.Li h.Liang y.f.Liang y.T.Liang G.R.Liao L.Z.Liao j.Libby c.X.Lin D.X.Lin b.Liu b.j.Liu c.X.Liu D.Liu D.y.Liu f.h.Liu fang Liu feng Liu h.b.Liu h.L Liu h.m.Liu huanhuan Liu huihui Liu j.b.Liu j.y.Liu K.y.Liu Kai Liu Ke Liu Q.Liu S.b.Liu X.Liu y.b.Liu Z.A.Liu Zhiqing Liu y.f.Long X.c.Lou h.j.Lu j.D.Lu j.G.Lu y.Lu y.P.Lu c.L.Luo m.X.Luo P.W.Luo T.Luo X.L.Luo S.Lusso X.R.Lyu f.c.ma h.L.ma L.L.ma m.m.ma Q.m.ma X.N.ma X.X.ma X.y.ma y.m.ma f.E.maas m.maggiora S.maldaner Q.A.malik A.mangoni y.j.m.o Z.P.mao S.marcello Z.X.meng j.G.messchendorp G.mezzadri j.m.n T.j.m.n R.E.mitchell X.h.mo y Institute of high Energy Physics Beijing 100049China beihang University Beijing 100191China beijing Institute of Petrochemical Technology Beijing 102617China bochum Ruhr-University D-44780 BochumGermany carnegie mellon University PittsburghPennsylvania 15213USA central china Normal University Wuhan 430079China china center of Advanced Science and Technology Beijing 100190China cOmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan fudan University Shanghai 200443China G.I.budker Institute of Nuclear Physics Sb RAS(bINP) Novosibirsk 630090Russia GSI helmholtzcentre for heavy Ion Research Gmbh D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China hangzhou Normal University Hangzhou 310036China helmholtz Institute mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany henan Normal University Xinxiang 453007China henan University of Science and Technology Luoyang 471003China huangshan college Huangshan 245000China hunan Normal University Changsha 410081China hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INfN Laboratori Nazionali di frascati I-00044FrascatiItaly INfN Sezione di ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia johannes Gutenberg University of mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia justus-Liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany KVI-cART University of GroningenNL-9747 AA GroningenThe Netherlands Lanzhou University Lanzhou 730000China Liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the bESIII detector at s^(1/2)=4.600 GeV. The processes of e^+e^-→D_s^+■^(*0)K^- and D_s^+■~0K^- are observed for the first time and are found to be dominated by the modes D_s^+D_(s1)(2536)^-and D_s^+D_(s2)~*(2573)^-, respectively. The born cross sections are measured to be σ~b(e^+e^-→D_s^+■^(*0)K^-) =(10.1±2.3±0.8) pb and σ~b(e^+e^-→D_s^+■~0K^-) =(19.4±2.3± 1.6) pb, and the products of born cross section and the decay branching fraction are measured to be σ~b(e^+e^-→D_s^+D_(s1)(2536)^-+c.c.)·b(D_(s1)(2536)^-→■^(*0)K^-)=(7.5±1.8±0.7) pb and σ~b(e^+e^-→D_s^+D_(s2)~*(2573)^-+ c.c.)·b(D_(s2)~*(2573)^-→■~0 K^-)=(19.7 ± 2.9 ±2.0) pb. for the D_(s1)(2536)^-and D_(s2)~*(2573)^-mesons, the masses and widths are measured to be m(D_(s1)(2536)^-)=(2537.7±0.5 ±3.1) meV/c2, Γ(D_(s1)(2536)^-) =(1.7 ±1.2 ±0.6)meV, and m(D_(s2)~*(2573)^-)=(2570.7±2.0 ±1.7) meV/c^2, Γ(D_(s2)~*(2573)^-)=(17.2 ±3.6 ±1.1) meV. The spin-parity of the D_(s2)~*(2573)^-meson is determined to be j^p= 2^+. In addition, the processes e^+e^-→D_s^+■^((*)0)K^-are searched for using the data samples taken at four(two) center-of-mass energies between 4.416(4.527) and 4.575 GeV, and upper limits at the 90% confidence level on the cross sections are determined.

关键词： cross section P-wave D_s mesons resonance parameters spin-parity bESIII

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