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带有防火保护的圆钢管约束钢筋混凝土柱抗火性能分析与设计

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工程力学 2024年第6期41卷 118-129页

作者：段泊池杨冬冬刘发起杨华结构工程灾变与控制教育部重点实验室(哈尔滨工业大学) 黑龙江哈尔滨150090 土木工程智能防灾减灾工业和信息化部重点试验室(哈尔滨工业大学) 黑龙江哈尔滨150090 扬州大学建筑科学与工程学院江苏扬州225127

抗火性能是圆钢管约束钢筋混凝土柱设计时的关键问题之一,尽管目前相关研究已逐渐完善,但带有防火保护条件下该类构件的抗火性能研究与设计仍不充分,已有的行业标准中构件高温稳定承载力公式未与常温公式相连续,且其中的防火保护层设计... 详细信息

抗火性能是圆钢管约束钢筋混凝土柱设计时的关键问题之一,尽管目前相关研究已逐渐完善,但带有防火保护条件下该类构件的抗火性能研究与设计仍不充分,已有的行业标准中构件高温稳定承载力公式未与常温公式相连续,且其中的防火保护层设计公式不具有明确的物理意义。基于ABAQUS软件,该文开展了带有防火保护圆钢管约束钢筋混凝土柱在ISO 834标准火灾作用下温度场和耐火极限的有限元分析,研究了荷载比、截面尺寸、长细比、防火保护层厚度等关键参数对构件耐火极限的影响规律,并提出了钢管温度、钢筋温度以及混凝土等效温度的简化计算公式。结果表明:随着防火保护层厚度的增大,构件的耐火极限近似线性增大。基于系统性参数分析,提出了带有防火保护圆钢管约束钢筋混凝土柱高温下截面承载力和稳定承载力设计公式,以用于确定构件达到不同耐火极限所需的防火保护层厚度,该方法保持了与现行标准中常温承载力计算公式的连续性。

关键词：圆钢管约束钢筋混凝土柱耐火极限防火保护设计方法有限元

Network pharmacology-based exploration of molecular mechanisms underlying therapeutic effects of Jianpi Huatan Quyu recipe on chronic heart failure with spleen Qi deficiency syndrome

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World Journal of Cardiology 2024年第7期16卷 422-435页

作者： Si-Qi Li dong-yu Min Jun-Wen Jiang Xiao-ying Li Xu-Na yang Wen-bo Gu Jia-Hui Jiang Li-Hao Chen Han Nan Ze-yu Chen Second Department of Cardiology The Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang 110000Liaoning ProvinceChina

BACKGROUND Chronic heart failure is a complex clinical *** Chinese herbal compound preparation Jianpi Huatan Quyu recipe has been used to treat chronic heart failure;however,the underlying molecular mechanism is still not *** To identify the effective active ingredients of Jianpi Huatan Quyu recipe and explore its molecular mechanism in the treatment of chronic heart *** The effective active ingredients of eight herbs composing Jianpi Huatan Quyu recipe were identified using the Traditional Chinese Medicine Systems Pharmacology Database and Analysis *** target genes of chronic heart failure were searched in the Genecards *** target proteins of active ingredients were mapped to chronic heart failure target genes to obtain the common drugdisease targets,which were then used to construct a key chemical componenttarget network using Cytoscape 3.7.2 *** protein-protein interaction network was constructed using the String *** Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment analyses were performed through the Metascape ***,our previously published relevant articles were searched to verify the results obtained via network *** A total of 227 effective active ingredients for Jianpi Huatan Quyu recipe were identified,of which quercetin,kaempferol,7-methoxy-2-methyl isoflavone,formononetin,and isorhamnetin may be key active ingredients and involved in the therapeutic effects of TCM by acting on STAT3,MAPK3,AKT1,JUN,MAPK1,TP53,TNF,HSP90AA1,p65,MAPK8,MAPK14,IL6,EGFR,EDN1,FOS,and other *** pathways identified by KEGG enrichment analysis include pathways in cancer,IL-17 signaling pathway,PI3K-Akt signaling pathway,HIF-1 signaling pathway,calcium signaling pathway,cAMP signaling pathway,NF-kappaB signaling pathway,AMPK signaling pathway,*** studies on Jianpi Huatan Quyu recipe suggested that this Chinese compound preparation can regulate the TNF-α,IL-6,MAPK

关键词： Jianpi Huatan Quyu recipe Traditional Chinese medicine Chronic heart failure Data mining Network pharmacology Bioinformatics Spleen Qi deficiency syndrome

Diamond-based electron emission:Structure,properties and mechanisms

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Chinese Physics B 2024年第9期33卷 165-177页

作者： Liang-Xue Gu Kai yang yan Teng Wei-Kang Zhao Geng-you Zhao Kang-Kang Fan bo Feng Rong Zhang you-Dou Zheng Jian-dong ye Shun-Ming Zhu Kun Tang Shu-Lin Gu School of Electronic Science and Engineering Nanjing UniversityNanjing 210046China

Diamond has an ultrawide bandgap with excellent physical properties,such as high critical electric field,excellent thermal conductivity,high carrier mobility,*** with a hydrogen-terminated(H-terminated)surface has a negative electron affinity(NEA)and can easily produce surface electrons from valence or trapped electrons via optical absorption,thermal heating energy or carrier transport in a PN *** NEA of the H-terminated surface enables surface electrons to emit with high efficiency into the vacuum without encountering additional barriers and promotes further development and application of diamond-based emitting *** article reviews the electron emission properties of H-terminated diamond surfaces exhibiting NEA *** electron emission is induced by different physical *** advancements in electron-emitting devices based on diamond are also ***,the current challenges and future development opportunities are discussed to further develop the relevant applications of diamond-based electronemitting devices.

关键词： diamond negative electron affinity (NEA) PN junction electron emission

“第二个结合”培育中国特色金融文化:基本条件、路径根基与践行原则

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经济学动态 2024年第2期 17-31页

作者：董志勇沈博北京大学经济学院、北京大学习近平新时代中国特色社会主义思想研究院现代化研究中心 100871 中国社会科学院经济研究所 100836

走中国特色金融发展之路,建设“金融强国”,是中国式现代化的题中应有之义。中国金融界的重要任务,已不仅在于推进西方现代金融理论与中国本土金融实践的结合,还在于推进马克思主义金融理论与中华优秀传统文化的有机结合,培育中国特色... 详细信息

走中国特色金融发展之路,建设“金融强国”,是中国式现代化的题中应有之义。中国金融界的重要任务,已不仅在于推进西方现代金融理论与中国本土金融实践的结合,还在于推进马克思主义金融理论与中华优秀传统文化的有机结合,培育中国特色金融文化。中华优秀传统文化蕴含的货币金融思想,形塑着服务于中华民族现代文明建设的中国特色现代金融体系的历史文化根基,为马克思主义金融理论的“第二个结合”创造了基本条件。马克思主义金融理论与中国传统金融思想在政治性和人民性立场上的高度契合性,则为“第二个结合”奠定路径根基,即紧抓本土金融故事灵韵,将优秀传统金融文化精神注入现代金融理论,实现本土传统货币金融智慧与现代金融理论的有机结合。在这一过程中,应注意坚持人民至上、坚持自立自信、坚持守正创新、坚持问题导向、坚持系统观念、坚持胸怀天下六项基本原则。

关键词： “第二个结合” 马克思主义金融理论中国特色金融文化金融强国

骶髂关节复位对儿童Tile C型骨盆骨折治疗效果的影响

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中华创伤骨科杂志 2024年第5期26卷 385-390页

作者：王波张志群董展南京医科大学附属儿童医院骨科南京210008

目的探讨骶髂关节复位对儿童Tile C型骨盆骨折治疗效果的影响。方法回顾性分析南京医科大学附属儿童医院骨科2017年3月至2022年1月期间连续收治的28例Tile C型儿童骨盆骨折患儿资料。男17例,女11例;年龄(10.2±3.1)岁。所有患儿根据术... 详细信息

目的探讨骶髂关节复位对儿童Tile C型骨盆骨折治疗效果的影响。方法回顾性分析南京医科大学附属儿童医院骨科2017年3月至2022年1月期间连续收治的28例Tile C型儿童骨盆骨折患儿资料。男17例,女11例;年龄(10.2±3.1)岁。所有患儿根据术中是否复位骶髂关节分为2组:骶髂关节不复位(NRSJ)组16例和骶髂关节复位(RSJ)组12例。比较两组患儿的术前一般资料、手术时间、术中出血量、术前及术后1周骨盆对角线长度、末次随访时Cole骨盆骨折效果评分。结果两组患儿术前一般资料及术前骨盆对角线长度比较差异均无统计学意义(P>0.05),具有可比性。NRSJ组患儿手术时间[(77.0±12.9)min]显著短于RSJ组[(104.7±24.3)min],术中出血量[(32.8±7.6)mL]显著少于RSJ组[(65.7±13.4)mL],术后1周骨盆对角线长度[(27.7±5.3)mm]显著长于RSJ组[(4.0±1.2)mm],差异均有统计学意义(P0.05)。末次随访时Cole骨盆骨折效果评分:NRSJ组优、良、中、差分别为2、3、5、6例,显著差于RSJ组的9、2、1、0例,差异有统计学意义(P<0.05)。结论儿童Tile C型骨盆骨折术中复位骶髂关节至关重要,虽然相比不复位骶髂关节,手术时间延长、术中出血量增多,但骨盆复位质量更高,可以进一步矫正骨盆环畸形,改善Cole骨盆骨折效果评分。

关键词：儿童骶髂关节外科手术骨盆骨折预后

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脾肿大在门静脉高压症外科中的地位

世界华人消化杂志 2024年第4期32卷 248-253页

作者：董伟褚海波同济大学附属东方医院胶州医院普通外科山东省青岛市266300

脾脏是机体重要的免疫器官,许多功能独一无二,同时兼有代谢和内分泌调节功能.当今,对门静脉高压症脾肿大,有害或者有益仍是个迷,外科的“切”与“保”一直是争论的焦点,并形成两派.鉴于脾肿大在门静脉高压症发展与治疗中所具有的特殊地... 详细信息

脾脏是机体重要的免疫器官,许多功能独一无二,同时兼有代谢和内分泌调节功能.当今,对门静脉高压症脾肿大,有害或者有益仍是个迷,外科的“切”与“保”一直是争论的焦点,并形成两派.鉴于脾肿大在门静脉高压症发展与治疗中所具有的特殊地位与作用,笔者结合自己长期的临床实践与基础研究,在这一领域不断传承与积累,改进与创新,对这一问题作一阐述,以此推动我国脾功能与脾外科的进一步发展.

关键词：脾肿大门静脉高压症外科

Focus on laboratory tests related to the pathological types of lupus nephritis to implement renal biopsy as early as possible:clinical and pathological analysis of 217 cases of single center lupus nephritis

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Clinical Research Communications 2024年第3期7卷 43-47页

作者： Xiao-yu Wang Hong-dong Li bo-Wen Tian Ping Wei Shu-Mei Shi Department of Nephrology the 960th Hospital of the PLA Joint Logistics Support ForceJinan 250031China. Department of Dermatology the 960th Hospital of the PLA Joint Logistics Support ForceJinan 250031China.

Objective:To analyze the clinical and laboratory indices of patients with lupus nephritis(LN)of different pathological types and explore the related factors of LN pathological classification,it is helpful to grasp the timing of renal ***:The clinical manifestations,laboratory parameters and renal pathological types of LN patients in recent 20 years were analyzed retrospectively by SPSS 26.0 ***:In this study,the first three pathological types were V,IV,V+IV;latent nephritis was common in type II and V;nephritic syndrome was common in type V;nephrotic syndrome was common in type V+IV;chronic renal insufficiency group was mostly type IV;pathological types were correlated with serum creatinine,C3,albumin and erythrocyte sedimentation rate(r=0.315,Py correlated(r=0.315,Py different among LN patients of different pathological ***:LN is closely related to clinical pathology,clinical manifestations,comprehensive analysis of laboratory indicators and SLEDAI score to make a preliminary prediction of LN pathological type,help to initially assess the severity of pathology,improve the timing of renal biopsy implementation,optimize the timing of treatment.

关键词： systemic lupus erythematosus lupus nephritis clinical features pathological types

Assessment of cheese sign and its association with vascular risk factors:Data from PUMCH dementia cohort

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Chinese Medical Journal 2024年第7期137卷 830-836页

作者： Xinying Huang bo Hou Jie Wang Jie Li Li Shang Chenhui Mao Liling dong Caiyan Liu Feng Feng Jing Gao Bin Peng Department of Neurology State Key Laboratory of Complex Severe and Rare DiseasePeking Union Medical College HospitalChinese Academy of Medical Science and Peking Union Medical CollegeBeijing 100730China Department of Radiology Peking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China

Background:In the clinic,practitioners encounter many patients with an abnormal pattern of dense punctate magnetic resonance imaging(MRI)signal in the basal ganglia,a phenomenon known as"cheese sign".This sign is reported as common in cerebrovascular diseases,dementia,and old ***,cheese sign has been speculated to consist of dense perivascular space(PVS).This study aimed to assess the lesion types of cheese sign and analyze the correlation between this sign and vascular disease risk ***:A total of 812 patients from Peking Union Medical College Hospital(PUMCH)dementia cohort were *** analyzed the relationship between cheese sign and vascular *** assessing cheese sign and defining its degree,the abnormal punctate signals were classified into basal ganglia hyperintensity(BGH),PVS,lacunae/infarctions and microbleeds,and counted *** type of lesion was rated on a four-level scale,and then the sum was calculated;this total was defined as the cheese sign *** and Age-Related White Matter Changes(ARWMC)scores were used to evaluate the paraventricular,deep,and subcortical gray/white matter ***:A total of 118 patients(14.5%)in this dementia cohort were found to have cheese ***(odds ratio[OR]:1.090,95%confidence interval[CI]:1.064-1.120,Pypertension(OR:1.828,95%CI:1.123-2.983,P=0.014),and stroke(OR:1.901,95%CI:1.092-3.259,P=0.025)were risk factors for cheese *** was no significant relationship between diabetes,hyperlipidemia,and cheese *** main components of cheese sign were BGH,PVS,and lacunae/*** proportion of PVS increased with cheese sign ***:The risk factors for cheese sign were hypertension,age,and *** sign consists of BGH,PVS,and lacunae/infarction.

关键词： Dementia Cerebrovascular disease Cheese sign Dense punctate lesions Basal ganglia Risk factor White matter

Application of deep learning methods combined with physical background in wide field of view imaging atmospheric Cherenkov telescopes

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Nuclear Science and Techniques 2024年第4期35卷 208-220页

作者： Ao-yan Cheng Hao Cai Shi Chen Tian-Lu Chen Xiang dong you-Liang Feng Qi Gao Quan-Bu Gou yi-Qing Guo Hong-bo Hu Ming-Ming Kang Hai-Jin Li Chen Liu Mao-yuan Liu Wei Liu Fang-Sheng Min Chu-Cheng Pan Bing-Qiang Qiao Xiang-Li Qian Hui-ying Sun yu-Chang Sun Ao-bo Wang Xu Wang Zhen Wang Guang-Guang Xin yu-Hua yao Qiang yuan yi Zhang School of Physics and Technology Wuhan UniversityWuhan 430072China School of Physics and Astronomy Yunnan UniversityKunming 650091China Ministry of Education The Key Laboratory of Cosmic Rays(Tibet University)Lhasa 850000China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences 19 A Yuquan RoadShijingshan DistrictBeijing 100049China College of Physics Sichuan UniversityChengdu 610064China School of Intelligent Engineering Shandong Management UniversityJinan 250357China Tsung‑Dao Lee Institute Shanghai Jiao Tong UniversityShanghai 200240China Suzhou Aerospace Information Research Institute Suzhou 215123China College of Physics Chongqing UniversityNo.55 Daxuecheng South RoadHigh‑tech DistrictChongqing 401331China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210008China

The High Altitude Detection of Astronomical Radiation(HADAR)experiment,which was constructed in Tibet,China,combines the wide-angle advantages of traditional EAS array detectors with the high-sensitivity advantages of focused Cherenkov *** objective is to observe transient sources such as gamma-ray bursts and the counterparts of gravitational *** study aims to utilize the latest AI technology to enhance the sensitivity of HADAR *** datasets and models with distinctive creativity were constructed by incorporating the relevant physical theories for various *** models can determine the type,energy,and direction of the incident particles after careful *** obtained a background identification accuracy of 98.6%,a relative energy reconstruction error of 10.0%,and an angular resolution of 0.22°in a test dataset at 10 *** findings demonstrate the significant potential for enhancing the precision and dependability of detector data analysis in astrophysical *** using deep learning techniques,the HADAR experiment’s observational sensitivity to the Crab Nebula has surpassed that of MAGIC and *** energies below 0.5 TeV and remains competitive with conventional narrow-field Cherenkov telescopes at higher *** addition,our experiment offers a new approach for dealing with strongly connected,scattered data.

关键词： VHE gamma-ray astronomy HADAR Deep learning Convolutional neural networks