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Importance of antimicrobial susceptibility testing for the management of eradication in Helicobacter pylori infection

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World Journal of Gastroenterology 2017年第16期23卷 2854-2869页

作者： Nazli arslan ozlem yilmaz Ebru Demiray-Gürbüz Department of Medical Microbiology Faculty of MedicineDokuz Eylül UniversityInciraltiIzmir 35340Turkey

The management of Helicobacter pylori(H. pylori) infection treatment differs from the common treatment protocol for other infectious diseases. Because culture-or molecular-guided approaches face several practical issues, such as the invasive procedures required to obtain gastric biopsy specimens and the lack of availability of routine laboratory testing in some places, H. pylori treatment includes the administration of two or three empirically selected antibiotics combined with a proton pump inhibitor rather than evidence-based eradication treatment. The efficacy of empirical therapy is decreasing, mostly due to increasing multiple resistance. Multiresistance to levofloxacin, clarithromycin, and metronidazole, which are commonly used in empirical treatments, appears to have increased in many countries. Mutations play a primary role in the antimicrobial resistance of H. pylori, but many different mechanisms can be involved in the development of antibiotic resistance. Determining and understanding these possible mechanisms might allow the development of new methods for the detection of H. pylori and the determination of antimicrobial resistance. A treatment based on the detection of antimicrobial resistance is usually more effective than empirical treatment. Nevertheless, such an approach before treatment is still not recommended in the Maastricht guidelines due to the difficulty associated with the routine application of available cultureor molecular-based susceptibility tests, which are usually administered in cases of treatment failure. The management of first and rescue treatments requires further research due to the steadily increase in antimicrobial resistance.

关键词： Helicobacter pylori Antimicrobial resistance Antimicrobial susceptibility testing Susceptibility-guided therapy Treatment management

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How much helpful is the capsule endoscopy for the diagnosis of small bowel lesions?

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World Journal of Gastroenterology 2006年第24期12卷 3906-3910页

作者： Osman Ersoy Bulent Sivri Serap arslan Figen Batman yusuf Bayraktar Hacettepe University Faculty of Medicine the Department of Gastroenterology AnkaraTurkey

AIM： To assess the practically usefulness and diagnostic yield of this new method in a group of patients with suspected small bowel lesions. METHODS： Capsule endoscopic （CE） examination by using M2A capsule endoscope TM （Given Imaging, yoqneam, Israel） was performed in thirty nine patients （26 males, 13 females） with suspected small intestinal lesions. The composing of the patients was as follows： obscure gastrointestinal bleeding in twenty three patients, known Crohn＇s disease in 6 patients, in whom CE was used to evaluate the severity and extension of the diseases, chronic diarrhea in 8 patients, abdominal pain in one patient and malignancy in one patient with unknown origin. RESULTS： In two patients CE failed. Different abnormalities were revealed in 26 patients overall. Detection rate of abnormalities was highest among patients with obscure gastrointestinal bleeding and the source of bleeding was demonstrated in 17 of 23 patients with obscure bleeding （73.9%）. Entero-Behcet was diagnosed in two patients by CE as a source of obscure gastrointestinal bleeding. In 6 patients with known Crohn＇s disease, CE revealed better evaluation of the disease extension. In 3 of 8 （37.5%） patients with chronic diarrhea; CE revealed some mucosal abnormalities as the cause of chronic diarrhea. In a patient with unexplained abdominal pain and in a cancer patient with unknown origin, CE examination was normal. CONCLUSION： In our relatively small series, we found that capsule endoscopy is a useful diagnostic tool particularly in diagnosis of obscure gastrointestinal bleeding, chronic diarrhea and in estimating the extension of Crohn＇s disease.

关键词： Capsule endoscopy Obscure gastrointestinalbleeding Crohn's disease Behcet's disease

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New Hybrid EWMA Charts for Efficient Process Dispersion Monitoring with Application in Automobile Industry

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Computer Modeling in Engineering & Sciences 2022年第5期131卷 1171-1195页

作者： Xuechen Liu Majid Khan Zahid Rasheed Syed Masroor Anwar Muhammad arslan Faculty of Economics Taiyuan Normal UniversityTaiyuan030619China Department of Mathematics and Statistics Riphah International UniversityIslamabad44000Pakistan Department of Mathematics Women University of Azad Jammu and KashmirBagh12500Pakistan Department of Statistics University of Azad Jammu and KashmirMuzaffarabad13100Pakistan School of Statistics Shanxi University of Finance and EconomicsTaiyuan030619China

The EWMAcharts are thewell-knownmemory-type charts used formonitoring the small-to-intermediate shifts in the process parameters(location and/or dispersion).The hybrid EWMA(HEWMA)charts are enhanced version of the EWMA charts,which effectivelymonitor the process *** paper aims to develop two new uppersided HEWMAcharts for monitoring shifts in process variance,i.e.,HEWMA1 and HEWMA2 *** design structures of the proposed HEWMA1 and HEWMA2 charts are based on the concept of integrating the features of two ***1 and HEWMA2charts plotting statistics are developed using one EWMAstatistic as input for the other *** Carlo simulations method is used as a computational technique to determine the numerical results for the performance characteristics,such as average run length(ARL),median run length,and standard deviation run length(SDRL)for assessing the performance of the proposed HEWMA1 and HEWMA2 *** addition,to evaluate the overall performance of the proposed HEWMA1 and HEWMA2 charts,other numerical measures consisting of the extra quadratic loss(EQL),relative average run length(RARL),and performance comparison index(PCI)are also *** proposed HEWMA1 and HEWMA2 charts are compared to some existing charts,such as CH,CEWMA,HEWMA,AEWMAHHW1,HHW2,AIB-EWMA-I,and AIB-EWMA-II charts,on the basis aforementioned numerical *** comparison reveals that the proposed HEWMA1 and HEWMA2 charts achieve better detection ability against the existing *** the end,a real-life data application is also provided to enhance the implementation of the proposed HEWMA1 and HEWMA2 charts practically.

关键词： Average run length extra quadratic loss memory-type charts Monte Carlo simulations smoothing parameter

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等离子体技术制备具有亚微米颗粒结构的球化W-Cu伪合金微粉

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Transactions of Nonferrous Metals Society of China 2024年第2期34卷 592-603页

作者： A.V.SAMOKHIN N.V.ALEKSEEV A.A.DOROFEEV A.A.FADEEV M.A.SINAySKIy I.D.ZAVERTIAEV y.V.GRIGORIEV Institute of Metallurgy and Materials Science Russian Academy of SciencesMoscow 119334Leninsky prospect 49Russian Federal Scientific Research Center“Crystallography and Photonics” Russian Academy of SciencesMoscow 119334Leninsky prospect 59Russian

采用复杂多级方法研究并证实制备具有亚微米/纳米级内部结构的球形W-Cu复合微粉的可能性。首先,采用等离子体化学合成法制备具有核壳结构的W-Cu纳米粉末(W核及Cu壳)。然后,将W-Cu纳米粉末与蔗糖的水悬浮液进行喷雾干燥,形成25~63μm的微... 详细信息

采用复杂多级方法研究并证实制备具有亚微米/纳米级内部结构的球形W-Cu复合微粉的可能性。首先,采用等离子体化学合成法制备具有核壳结构的W-Cu纳米粉末(W核及Cu壳)。然后,将W-Cu纳米粉末与蔗糖的水悬浮液进行喷雾干燥,形成25~63μm的微粒,收率为50%。最后,用热等离子体射流处理由纳米粉末组成的微粒,形成致密的球形W-Cu颗粒。成品粉末的球化度为90%~95%,体积密度为8.1 g/cm^(3),流动性约为12 s/50 g,杂质中O、C和H的含量(质量分数)分别为0.7%、0.02%~0.2%和0.03%~0.05%。

关键词： W-Cu复合材料等离子体化学合成造粒等离子体球化纳米颗粒微粒微粉

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A detailed comparison of the composition of(RE)-Ba-Cu-O-Ag bulk superconductors

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Superconductivity 2024年第1期9卷 87-94页

作者： J.V.J.Congreve y.Shi A.R.Dennis H.Druiff N.C.Tutt D.A.Cardwell J.H.Durrell Department of Engineering University of CambridgeCambridgeUK

The homogeneity of the microstructure and composition are critical in determining the properties of rare earthbarium‐cuprate,single grain bulk superconductors[(RE)BCO].The magnitude of the trapped magnetic field achieveable in these technologically important materials,in particular,is influenced heavily by the size and distribution of(RE)_(2)BaCuO_(x)(RE‐211)flux pinning inclusions in the bulk microstructure,whereas the size and distribution of silver agglomerates present within the bulk superconducting matrix correlate directly with improved mechanical *** careful engineering,these materials have significant potential for application in range of devices related to energy storage,medicine,electro‐magnetic machinery and microelectronic *** of(RE)BCO bulk superconductors typically involves heating a powder compact above its peritectic decomposition temperature followed by slow cooling to facilitate the growth of a single ***(RE)BCO composition has a different peritectic temperature and growth rate,which,therefore,necessitates different requirements in the heating *** fabrication temperature and growth rate,for example,may have an effect on the RE‐211 and silver distribution,which may,in turn,affect the superconducting properties of the resulting single *** this work we compare the distributions of silver and RE‐211 in the single grain microstructures of yBCOAg,GdBCO‐Ag,EuBCO‐Ag and SmBCO‐Ag bulk superconductors using optical microscopy,scanning electron microscopy and energy dispersive X‐ray *** observe that the distributions are very similar along both the a/b‐axis and c‐axis of these *** suggests that factors other than the maximum temperature used to achieve peritectic decomposition and the rate of single grain growth are particularly influential in determining the properties of the as‐processed samples in the top seeded melt growth *** observation demonstrates there is freedom to us

关键词： yBCO‐Ag GdBCO‐Ag SmBCO‐Ag EuBCO‐Ag Composition Bulk superconductor

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Joint Non-Orthogonal Multiple Access (NOMA) & Walsh-Hadamard Transform: Enhancing the Receiver Performance

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China Communications 2018年第9期15卷 160-177页

作者： Muhammad Rehan Usman Arsla Khan Muhammad arslan Usman Soo young Shin Department of Electrical Engineering The Superior College (University Campus) Department of IT Convergence Engineering Kumoh National Institute of Technology (KIT) Department of Electrical Engineering COMSATS University Islamabad Lahore Campus

Non-orthogonal multiple access(NOMA) is a new access method to achieve high performance gains in terms of capacity and throughput, so it is currently under consideration as one of the candidates for fifth generation(5 G) technologies. NOMA utilizes power domain in order to superimpose signals of multiple users in a single transmitted signal. This creates a lot of interference at the receive side. Although the use of successive interference cancellation(SIC) technique reduces the interference, but to further improve the receiver performance, in this paper, we have proposed a joint Walsh-Hadamard transform(WHT) and NOMA approach for achieving better performance gains than the conventional NOMA. WHT is a well-known code used in communication systems and is used as an orthogonal variable spreading factor(OVSF) in communication systems. Application of WHT to NOMA results in low bit error rate(BER) and high throughput performance for both low and high channel gain users. Further, it also reduces peak to average power ratio(PAPR) of the user signal. The results are discussed in terms of comparison between the conventionalNOMA and the proposed technique, which shows that it offers high performance gains in terms of low BER at different SNR levels, reduced PAPR, high user throughput performance and better spectral efficiency.

关键词： Bit error rate (BER) non-orthogonal multiple access (NOMA) orthogonal frequency division multiplexing (OFDM) peak to average power ratio (PAPR) successive interference cancellation (SIC) throughput and Walsh-Hadamard transform (WHT).

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时间的刚性

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商业周刊（中文版） 2024年第12期 66-71页

作者： Tommy.y 不详

陶瓷表是一种采用高科技陶瓷复合材料制作的腕表,以其硬度高、光泽度好、质地轻、防磨损、抗过敏、不褪色等特质而受到青睐。陶瓷表的设计和制造体现了制表业的创新精神和对于材质的探索。这种材质的腕表不仅展现了优雅、精妙、简约的特... 详细信息

陶瓷表是一种采用高科技陶瓷复合材料制作的腕表,以其硬度高、光泽度好、质地轻、防磨损、抗过敏、不褪色等特质而受到青睐。陶瓷表的设计和制造体现了制表业的创新精神和对于材质的探索。这种材质的腕表不仅展现了优雅、精妙、简约的特质,还因其独特的物理刚性而备受推崇。

关键词：防磨损光泽度不褪色腕表创新精神抗过敏刚性陶瓷

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通透设计时间的旷野艺境

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商业周刊（中文版） 2024年第13期 74-79页

作者： Tommy.y 不详

制表技艺当中,带有透视的设计款式很具设计巧思,且工艺复杂。一方面要满足造型的需求,另一方面也对加工提出了苛刻的条件。因此能够同时达到功能与美感均不错的水准,的确需要功力。造型多元的透视设计,往往带来出其不意美感,给人一见倾... 详细信息

制表技艺当中,带有透视的设计款式很具设计巧思,且工艺复杂。一方面要满足造型的需求,另一方面也对加工提出了苛刻的条件。因此能够同时达到功能与美感均不错的水准,的确需要功力。造型多元的透视设计,往往带来出其不意美感,给人一见倾心的感觉。

关键词：出其不意美感造型透视

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Experimental Study of a Solar Thermal Incubator Using a Phase-Change Material for Off-Grid Use

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Open Journal of Applied Sciences 2024年第9期14卷 2471-2481页

作者： yéouélé Thio Bati Ernest Boya Bi Ekoun Paul Magloire Koffi Prosper Gbaha Laboratoire des Procds Industriels de Synthse de lEnvironnement et des Energies Nouvelles Institut National Polytechnique Flix Houphout-Boigny Yamoussoukro Cte dIvoire

The aim of this study was to provide a simple, easy-to-use incubation system for small-scale rural poultry farmers far from the electricity grid. To this end, a naturally ventilated solar thermal incubator was built and experimentally tested. A U-shaped evacuated tube collector and a wooden crate holding 50 eggs were used to build the solar thermal incubator. Water was used as the heat transfer fluid, and an EPCM was integrated into the incubation chamber for operation at night or when the sun was hidden. The heat generated by the solar collector and stored in the heat transfer fluid is transported to the incubation chamber by thermosiphon to heat the chamber. Temperature and humidity probes powered by a solar panel were placed at various locations to monitor the thermo-hygrometric efficiency of the incubation system. The incubator, heated by natural convection, proved to function normally, and the incubation chamber was maintained throughout the incubation period within a temperature range of 35.53˚C to 39.53˚C and relative humidity averaging 49.4% to 68.5%. The experiment was carried out by introducing 30 eggs and the results of the experimental study showed that the incubator’s efficiency was 87%. The performance tests gave a fertility rate of 93% and a hatching rate of 93%, i.e. 28 fertile eggs and 26 hatched eggs, respectively.

关键词： Solar Incubator Vacuum Tube Collector Encapsulated PCM Poultry Eggs

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Sentiment Analysis of Roman Urdu Sentence with Deep Neural Networks

Sentiment Analysis of Roman Urdu Sentence with Deep Neural N...

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作者： Muhammad arslan Manzoor 南京理工大学

学位级别：硕士

情感分析是对文本中表达的评论、情绪和情感进行的计算研究。近几年来,情感分析引起了业界和学术界的广泛关注。在世界各地,社交媒体已为人们提供了以母语共享个人观点的趋势。对于这些评论的情感分析,机器学习算法是研究者的主要选择... 详细信息

情感分析是对文本中表达的评论、情绪和情感进行的计算研究。近几年来,情感分析引起了业界和学术界的广泛关注。在世界各地,社交媒体已为人们提供了以母语共享个人观点的趋势。对于这些评论的情感分析,机器学习算法是研究者的主要选择。在提出了复杂的机器学习算法和硬件升级版本来运行实验之后,研究界开始转向利用深度学习完成情感分析任务。过去五年的背景研究证实,深度神经网络(CNN、RNN和扩展版LSTM)取得了显著的成绩。这些神经网络大多是单向的,需要大量的时间、内存和硬件资源。另外,目前的方法主要集中在对英语句子的分析上。对于一些少数民族语言来说,这仍然是一个挑战,比如罗马乌尔都语,它有一个更复杂的句子结构和众多的单字词汇变化。在本研究中,对于罗马乌尔都语的情感分析,我们提出了新颖的自注意力双向LSTM网络(Self-Attention Bidirectional LSTM,简称SA-BiLSTM)来处理句子结构和不一致的文本表达方式。在SA-BiLSTM中,自我注意用于关联整个句子、控制复杂的结构,BiLSTM用于提取上下文表示,以解决前后的词汇变化。本文网络还突破了传统网络单向性的局限性。此外,为了衡量其他模型在罗马乌尔都语分析中的性能,并与SA-BiLSTM进行比较,我们对罗马乌尔都语句子进行了预处理和规范化。我们在罗马乌尔都语的两个数据集中训练并评估了所有模型。SA-BiLSTM的有效设计使用较少的计算资源,并且在预处理和规范化后的数据集上的准确度分别为68.4%和69%。实验结果表明,与其他最新的深度语言网络模型相比,SA-BiLSTM具有更好的准确性。结果分析和比较证实,数据集的规范化使模型达到了更高的精度。此外,BERT最近在一个多语言数据集上取得了最好的成绩。BERT的结构中包含转换器的双向特性(自注意力层),与SA-BiLSTM中的思路一致。BERT在经过预处理和规范化的数据测试集上获得的结果要高于其在翻译成乌尔都语的XNLI数据集上的结果。

关键词：情感分析注意力机制长短期记忆文本分类罗马乌尔都语

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