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Recording the direct surgeon’s view with an operating microscopic view improves microscopic ophthalmic surgery training

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International Journal of Ophthalmology(English edition) 2023年第9期16卷 1555-1558页

作者： Masayuki Akimoto Kosei tomita Miyo yoshida yuki Hama Ophthalmology Osaka Red Cross HospitalTennoji-kuOsaka 543-8555Japan

AIM:To establish a recording system with a direct view of the surgeon to supplement video recording under an operating microscope,which lacks information on the movement and position of the surgeon’s hands,and to facilitate the reproduction of a skilled surgeon’s technique by a surgeon in ***:A small camera was attached to the operating microscope with a custom *** surgeon’s view and direct surgeon’s view through this new camera were recorded in the surgical recording *** movies were synchronized and analyzed how do surgeons handle the ***:A small camera attached to the operating microscope allowed the surgeon’s hands motion to be recorded without interfering with the surgeon’s *** surgeons used different methods to manipulate the ultrasound handpiece and the irrigation/aspiration *** in the simple paracentesis procedure,different surgeons used different ***-in-training were able to identify and improve their weaknesses by watching synchronized movies of their hand motions and microscopic ***:Simultaneous recording the surgical field out of the operating microscopic view by a small camera set on the microscope is comprehensive and improves surgeons-in-training understanding and learning surgeries.

关键词： operating microscopic view direct surgeon’s view video recording microscopic surgery training

Phase Behavior and Crystal Structure of Perovskite-Type Rare Earth Complex Oxides

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Journal of Rare Earths 2006年第6期24卷 668-672页

作者： Migaku Kobayashi Ryoko Katsuraya Tsubasa Nara yusuke tomita Hiromi Nakano Naoki Kamegashira Department of Chemistry and Biochemistry Numazu College of Technology 3600 Ooka Numazu 410-8501 Japan Ryukoku University Seta Otsu 520-2194 Japan Department of Materials Science Toyohashi University of Technology Tempaku-cho Toyohashi 441-8580 Japan

Several compounds of rare earth complex oxides containing manganese and titanium were synthesized in Ar, and their crystal structures were analyzed by powder X-ray diffraction data and Rietveld method. Structures of A0.67Ln0.33 Mn0.33Ti0.6703（A = Ca or Sr and Ln = rare earth） were found to have orthorhombic symmetry with the space group Pnrna, and their interatomic distances and bond angles were obtained. This space group was also derived from electron microscopic study. Electrical conductivity of Cao.67Ln0.33Mn0.33Ti0.6703 for several rare earth elements showed a semiconducting property with the activation energy of 0.4 eV. Some of these compounds of the strontium system show the antiferromagnetic properties below 10 K.

关键词： perovskite crystal structure X-ray diffraction alkaline earth rare earth manganese titanium oxide

Advances in the treatment of autism spectrum disorder:Wharton jelly mesenchymal stem cell transplantation

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World Journal of Methodology 2025年第1期15卷 72-79页

作者： Serdar Kabatas ErdinçCivelek Eyüp Can Savrunlu Umut Karaaslan Özlem yıldız Erdal Karaöz Department of Neurosurgery University of Health Sciences TurkeyGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Pediatric Allergy-Immunology Institute of Health Sciences Marmara UniversityIstanbul 34865Türkiye Center for Stem Cell&Gene Therapy Research and Practice University of Health Sciences TurkeyIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry University of Health SciencesGaziosmanpaşa Training and Research HospitalIstanbul 34255Türkiye Department of Child and Adolescent Psychiatry Kocaeli University Faculty of MedicineKocaeli 41001Türkiye Center for Regenerative Medicine and Stem Cell Research&Manufacturing Liv HospitalIstanbul 34340Türkiye Department of Histology and Embryology Istinye UniversityFaculty of MedicineIstanbul 34010Türkiye Center for Stem Cell and Tissue Engineering Research and Practice Istinye UniversityIstanbul 34340Türkiye

BACKGROUND Autism spectrum disorder(ASD)is a complex neurodevelopmental disorder with multifaceted *** recent studies,neuroinflammation and immune dysregulation have come to the forefront in its *** are studies suggesting that stem cell therapy may be effective in the treatment of *** To evolve the landscape of ASD treatment,focusing on the potential benefits and safety of stem cell *** A detailed case report is presented,displaying the positive outcomes observed in a child who underwent intrathecal and intravenous Wharton’s jelly-derived mesenchymal stem cells(WJ-MSCs)transplantation combined with *** The study demonstrates a significant improvement in the child’s functional outcomes(Childhood Autism Rating Scale,Denver 2 Developmental Screening Test),especially in language and gross motor *** serious side effects were encountered during the 2-year *** The findings support the safety and effectiveness of WJ-MSC transplantation in managing ASD.

关键词： Autism spectrum disorder Neurorehabilitation Stem cell transplantation Wharton jelly mesenchymal stem cells Inflammation

一种Sawyer马达驱动二维运动平台测量和控制系统设计(英文)

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纳米技术与精密工程 2006年第3期4卷 182-189页

作者： TANO M 高伟 DIAN S y KIyONO S tomita y MAKINO K MOTITA H 日本东北大学日本住友重工株式会社

介绍一种使用Sawyer马达驱动的平台和表面编码器组成的精密定位系统．该平台包括一个台板和若干线性脉冲马达推动器．台板由防腐钢板制成,在其表面加工了齿牙．线性脉冲马达推动器靠空气支承悬浮在台板上,用以驱动平台．每一驱动器均由... 详细信息

介绍一种使用Sawyer马达驱动的平台和表面编码器组成的精密定位系统．该平台包括一个台板和若干线性脉冲马达推动器．台板由防腐钢板制成,在其表面加工了齿牙．线性脉冲马达推动器靠空气支承悬浮在台板上,用以驱动平台．每一驱动器均由一个永久磁铁和两个驱动线圈组成,用以产生X向和y向的平台驱动力．设计了一种表面编码器用以测量和控制平台的运动．一个正弦格栅装在台板上,一个传感组件装在平台驱动器上．在该传感组件中有三个光学传感器,用以测量三个分离点上的X和y方向的位置,平台的θ_z向位置可以从传感器输出求得．开发了一种反馈控制系统用以控制平台运动．测量和反馈控制实验证明了该精密系统的可行性．

关键词：测量控制定位 Sawyer马达表面编码器正弦格栅传感器

Amount of TNF-αreleased from macrophagesreacting with polyethylene particles showeddose-dependent relationship to the totalsurface area of added particles

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Biosurface and Biotribology 2018年第4期4卷 122-127页

作者： Weiqi Shen Naohide tomita Miho Niikura Takuma Sugino Department of MechanicalEngineering and Science Kyoto UniversityKyotoJapan

The immune response to ultra-high molecular weight polyethylene wear debris is thought to beone of the majorcauses of osteolysis and aseptic *** in-vitro methodfor the measurement of the response is necessary in orderto priori estimate the lifespan of the *** is of importance to distinguish the bioactivity of various *** current research focused on the inverse culturing process,which was shown to be effective toevaluate the biological reaction of mouse macrophages and wear particles by estimating the amount of *** this study,several improvements were carried out through trial *** sheet wasintroduced instead of PVC seal to remove air bubbles and to eliminate the influence of potentially-attached *** along with experiments according to Stokes'law were also performed to determine the reaction time andthe minimum particle size that can be phagocytosed by macrophages in the improved *** authorsco-incubated mouse macrophages and polyethylene particles in different sizes,densities and molecular weights usingthe new *** result suggests that the amount of tumour necrosis factor-α(TNF-α)generated is dosagedependent on the total surface area of particles added regardless of particle size,density and molecular weight ofpolyethylene.

关键词： wear surface dosage

Restauro-G:A Rapid Genome Re-Annotation System for Comparative Genomics

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Genomics, Proteomics & Bioinformatics 2007年第1期5卷 53-58页

作者： Satoshi Tamaki Kazuharu Arakawa Nobuaki Kono Masaru tomita Institute for Advanced Biosciences Keio University Fujisawa 252-8520 Japan Department of Environ-mental Information Keio University Fujisawa 252-8520 Japan Institute for Advanced Biosciences Keio University Fujisawa 252-8520 Japan

of complete genome sequences submitted directly from sequencing projects are diverse in terms of annotation strategies and update frequencies. These inconsistencies make comparative studies difficult. To allow rapid data preparation of a large number of complete genomes, automation and speed are important for genome re-annotation. Here we introduce an open-source rapid genome re-annotation software system, Restauro-G, specialized for bacterial genomes. Restauro-G re-annotates a genome by similarity searches utilizing the BLASTLike Alignment Tool, referring to protein databases such as UniProt KB, NCBI nr, NCBI COGs, Pfam, and PSORTb. Re-annotation by Restauro-G achieved over 98% accuracy for most bacterial chromosomes in comparison with the original manually curated annotation of EMBL releases. Restauro-G was developed in the generic bioinformatics workbench G-language Genome Analysis Environment and is distributed at http：//***/ under the GNU General Public License.

关键词： bioinformatics software annotation G-language Genome Analysis Environment complete genomes

Novel re-intervention device for occluded multiple uncovered self-expandable metal stent(with video)

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Hepatobiliary & Pancreatic Diseases International 2023年第4期22卷 434-436页

作者： Takeshi Ogura yuki Uba Mitsuki tomita Kimi Bessho Hiroki Nishikawa 2nd Department of Internal Medicine Osaka Medical and Pharmaceutical University2-7 DaigakuchouTakatsukishiOsaka 569-8686Japan

To the Editor:Obstructive jaundice due to unresectable malignant hilar obstruction can be treated by deployment of bilateral uncovered self-expandable metal stents(UCSEMSs),which enable longer stent patency to be obtained compared with multiple plastic stents[1-3].However,re-intervention is needed if obstructive jaundice occurs after bilateral UCSEMS *** re-intervention procedures,insertion of the stent delivery system across the mesh of a UCSEMS and into the bile duct can be challenging.A novel drill dilator has recently become available in Japan(Tornus ES;Asahi Intecc,Nagoya,Japan)(Fig.1)[4].The tract is easily dilated using a clockwise *** herein describe a successful re-intervention using this device for a patient with occluded bilateral UCSEMSs.

关键词： stent struction Asahi

Fabrication of luminescent patterns using aggregation-induced emission molecules by an electrolytic micelle disruption approach

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Aggregate

Aggregate 2023年第1期4卷 231-237页

作者： yaqian Zhou Elena Villani Tomoyuki Kurioka yanyun Zhang Ikuyoshi tomita Shinsuke Inagi Department of Chemical Science and Engineering School of Materials and Chemical TechnologyTokyo Institute of TechnologyYokohamaJapan PRESTO Japan Science and Technology Agency(JST)KawaguchiJapan

Herein,we report an electrochemical strategy that could control the location of aggregation-induced emission(AIE)molecules on patterned electrodes in a precise and facile way,producing photoluminescent and electrochemiluminescent patterns with a variety of colors.A micelle composed of electroactive surfactants was broken during the electrooxidation process,in which AIE molecules inside these micelles were released on patterned *** patterned electrodes were pretreated by not only metal,but also multifarious conducting polymers(CPs).An in-depth investigation clarified a correlation between the variety of CPs used as electrodes and the oxidation rate of the electroactive surfactant due to different catalytic performances of ***,combined with wireless and gradient features of bipolar electrochemistry,a gradient luminescent pattern was easily *** current studies suggest more abundant luminescent patterns using AIE luminophores can be developed by such an electrochemical method,in both of graphical shapes and emitting colors.

关键词： aggregation-induced emission bipolar electrochemistry catalysis conducting polymers electrochemiluminescence electrolytic micelle disruption

Molecular Dynamics Simulation of Behaviours of Non-Polar Droplets Merging and Interactions with Hydrophobic Surfaces

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Journal of Bionic Engineering 2008年第4期5卷 271-281页

作者： y.y. yan C.y. Ji School of the Built Environment University of Nottingham Nottingham NG7 2RD UK

This paper presents a molecular dynamics simulation of the behaviours of non-polar droplets merging and also the fluid molecules interacting with a hydrophobic surface. Such behaviours and transport phenomena are popular in general microchannel flow boiling and two-phase flow. The droplets are assumed to be composed of Lennards-Jones type molecules. Periodic boundary conditions are applied in three coordinate directions of a 3-D system, where there exist two liquid droplets and their vapour. The two droplets merge when they come within the prescribed small distance. The merging of two droplets apart from each other at different initial distances is tested and the possible larger （or critical） non-dimensional distance, in which droplets merging can occur, is discussed. The evolution of the merging process is simulated numerically by employing the Molecular Dynamics （MD） method. For interactions with hydrophobic solid wall, a system with fluid confined between two walls is used to study the wetting phenomena of fluid and solid wall. The results are compared with those of hydrophilic wall to show the unique characteristics of hydrophobic interactions by microscopic methods.

关键词： molecular dynamics simulation mist flow droplets merging hydrophobic wetting