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Monteggia type-Ⅰequivalent fracture in a fourteen-month-old child:A case report

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World Journal of Clinical Cases 2021年第30期9卷 9228-9235页

作者： Ming-Lei Li Wei-Zheng Zhou lian-yong Li Qi-Wei Li Department of Pediatric Orthopaedics Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina

BACKGROUND Monteggia and equivalent lesions are relatively rare but result in severe injuries in childhood,typically affecting children between 4 and 10 years *** diagnosis and treatment of an equivalent Monteggia lesion is more complicated than those of a typical Monteggia *** type of lesion may be challenging and may lead to serious complications if not treated *** Monteggia equivalent type I lesions have been reported in a few reports,all of which the patients were all over 4 years *** SUMMARy A 14-mo-old boy was referred to our clinic after falling from his bed 10 d *** regard to the clinical examination,an obvious swollen and angular deformity was noted on his right *** radiographs and reconstructed computed tomography scans showed a Monteggia type I fracture and *** resonance imaging(MRI)confirmed a type I Monteggia equivalent lesion consisting of ulnar fracture and Salter-Harris type I injury in the proximal *** radial head was still in the joint,and only the radial metaphysis was displaced *** reduction and pinning of both displaced radial and ulnar fractures achieved an excellent result with full *** We recommend MRI examination or arthrography during reduction,especially if the secondary ossification center has not appeared.

关键词： Children Monteggia fracture-dislocation Monteggia equivalent lesion Radial neck fracture Ulnar fracture Case report

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重庆市卫生应急人员能力建设现况及影响因素

中国热带医学 2024年第8期24卷 982-987页

作者：宿昆刘恋孙军银涛李洪明唐文革陈耀凯吴瑞重庆市公共卫生医疗救治中心重庆400035 重庆市疾病预防控制中心重庆400700 重庆市急救医疗中心重庆400010

目的了解和评估重庆市公共卫生应急人员能力建设现况,分析影响和制约其能力建设的主要因素,提出对策建议,为进一步提升重庆市卫生应急能力提供参考依据。方法采用问卷调查和专家访谈相结合的方式,从一般情况、健康状况、培训演练情况和... 详细信息

目的了解和评估重庆市公共卫生应急人员能力建设现况,分析影响和制约其能力建设的主要因素,提出对策建议,为进一步提升重庆市卫生应急能力提供参考依据。方法采用问卷调查和专家访谈相结合的方式,从一般情况、健康状况、培训演练情况和卫生应急能力4个维度分析重庆市39家疾病预防控制中心和10家医疗机构的卫生应急人员能力建设现状,采用Spearman等级相关分析自评健康状况与自评睡眠质量之间的相关性,利用多重线性回归分析卫生应急能力的影响因素。结果重庆市卫生应急人员超重及以上(体质量指数≥24 kg/m^(2))达34.85%,日常开展过健康监测者仅占37.92%,应急状态出现健康问题者占9.19%;年均参加2次及以上培训、2次及以上演练和1次及以上体能考核的比例分别为52.07%、22.76%和31.12%;人员应急能力平均得分为76.11分,其中最低为政策建议能力(48.59分);医学背景专业(β=1.025)、从事应急工作年限越长(β=1.774)、自评身体状况越好(β=3.664)、自评心理状况越好(β=4.362)、年均参加2次及以上演练(β=2.696)的人员,其卫生应急能力得分较高(P<0.05)。结论重庆市卫生应急能力建设仍存在一些短板,未来应优化卫生应急队伍人员结构,强化应急人员平时体能训练和应急状态下健康监测与管理,持续推进培训演练实战化、情景化和专业化,多方位多途径全面提升卫生应急人员身心素质和专业素养。

关键词：卫生应急能力现况影响因素重庆

Reformation of deep clastic reservoirs with different diagenetic intensities by microfractures during late rapid deep burial: Implications from diagenetic physical simulation of Cretaceous Qingshuihe Formation in the southern margin of Junggar Basin, NW China

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Petroleum Exploration and Development 2023年第2期50卷 346-359页

作者： JIN Jun XIAN Benzhong lian Lixia CHEN Sirui WANG Jian LI Jiaqi Research Institute of Experiment and Detection PetroChina Xinjiang Oilfield CompanyKaramayXinjiang 834000China CNPC Key Laboratory of Conglomerate Reservoir Exploration and Development KaramayXinjiang 834000China Xinjiang Laboratory of Petroleum Reserves in Conglomerate KaramayXinjiang 834000China College of Geosciences China University of Petroleum(Beijing)Beijing 102249China State Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing 102249China

Constrained by the geological burial history of Cretaceous Qingshuihe Formation in the southern margin of Junggar Basin, the diagenetic physical simulation experiment was carried out with the low-mature sandstone samples taken from the outcrop area. then, coupling with the regional geological data, the reformation of reservoirs with different diagenetic intensities by microfractures and the significance of microfractures for development of high-quality reservoirs were discussed. the results show that the large-scale microfractures were formed in the stage of late rapid deep burial, roughly equivalent to the period when organic acids were filled. the microfractures created good conditions for migration of oil and gas in deep and ultra-deep clastic rocks, and also enabled the transport of organic acids to the reservoirs for ensuing the late continuous dissolution of cements and particles. the existence of matrix pores and microfractures in the reservoirs before the rapid deep burial determined how the microfractures formed during rapid deep burial improved the reservoir quality. If matrix pores and microfractures were more developed and the cementation degree was lower before the rapid deep burial, the microfractures would be more developed and the dissolution degree would be higher during the late rapid deep burial, and so the reservoir quality would be improved more greatly, which can increase the reservoir permeability by up to 55%. If cementation was very strong, but matrix pores were not developed and microfractures existed locally before the rapid deep burial, the microfractures would also be more developed during the late rapid deep burial, which can increase the reservoir permeability by 43%. If cementation was strong, matrix pores were absent, and microfractures were not developed, limited microfractures would be formed during the late rapid deep burial, which can increase the reservoir permeability by only 16%. Formation of large-scale microfractures during

关键词： rapid deep burial microfracture physical simulation deep reservoir Cretaceous Qingshuihe Formation Junggar Basin

the role of vascularization in nerve regeneration of nerve graft

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Neural Regeneration Research 2020年第9期15卷 1573-1579页

作者： tiam M.Saffari Meiwand Bedar Caroline A.Hundepool Allen t.Bishop Alexander y.Shin Department of Orthopedic Surgery Mayo ClinicRochesterMNUSA Department of Plastic Reconstructive and Hand SurgeryErasmus Medical CenterRotterdamthe Netherlands

Vascularization is an important factor in nerve graft survival and function. the specific molecular regulations and patterns of angiogenesis following peripheral nerve injury are in a broad complex of pathways. this review aims to summarize current knowledge on the role of vascularization in nerve regeneration, including the key regulation molecules, and mechanisms and patterns of revascularization after nerve injury. Angiogenesis, the maturation of pre-existing vessels into new areas, is stimulated through angiogenic factors such as vascular endothelial growth factor and precedes the repair of damaged nerves. Vascular endothelial growth factor administration to nerves has demonstrated to increase revascularization after injury in basic science research. In the clinical setting, vascularized nerve grafts could be used in the reconstruction of large segmental peripheral nerve injuries. Vascularized nerve grafts are postulated to accelerate revascularization and enhance nerve regeneration by providing an optimal nutritional environment, especially in scarred beds, and decrease fibroblast infiltration. this could improve functional recovery after nerve grafting, however, conclusive evidence of the superiority of vascularized nerve grafts is lacking in human studies. A well-designed randomized controlled trial comparing vascularized nerve grafts to non-vascularized nerve grafts involving patients with similar injuries, nerve graft repair and follow-up times is necessary to demonstrate the efficacy of vascularized nerve grafts. Due to technical challenges, composite transfer of a nerve graft along with its adipose tissue has been proposed to provide a healthy tissue bed. Basic science research has shown that a vascularized fascial flap containing adipose tissue and a vascular bundle improves revascularization through excreted angiogenic factors, provided by the stem cells in the adipose tissue as well as by the blood supply and environmental support. While it was previou

关键词： angiogenesis fascial flap nerve graft nerve injury nerve regeneration peripheral nerve vascular endothelial growth factor vascularization vascularized nerve graft

VISUALIZAtION OF DyNAMIC ORGANIZAtION OF CytOSKELEtON GELS IN LIVING CELLS By HyBRID-SPM

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Chinese Journal of Polymer Science 2003年第2期21卷 169-174页

作者： K.Kawabata y.Sado M.Nagayama t.Nitta K.Nemoto y.Koyama H.Haga Divisions of Biological Sciences Graduate School of Science Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDivisions of Physics Graduate School of Science. Hokkaido University 060-0810 SapporoDepartment of Biochemistry Hokkaido University Graduate School of Medicine Sapporo 060-8638 JapanDivisions of Physics Graduate School of Science Hokkaido University 060-0810 Sapporo

We succeeded in performing of hybrid Scanning Probe Microscopy (hybrid-SPM) in which mechanical-SPM andfluorescence microscopy are combined. this technique is able to measure simultaneously mechanical properties anddistribution of cytoskeletons of living cells by using green fluorescent protein. We measured evolution of both local elasticityand distributions of actin stress fibers in an identical fibroblast living in physiological conditions. the SPM experimentsrevealed that stiffer lines develop in living cells, which correspond to actin stress fibers. the elasticity of the actin stressfibers is as high as 100 kPa. We discuss mechanical effects on the development of actin filament networks.

关键词： Scanning probe microscopy Green fluorescent protein Fibroblast Cell migration, Cytoskeleton Elasticity

基于电力大数据技术的配电台区拓扑关系识别流程研究

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自动化与仪器仪表 2024年第5期 119-121,126页

作者：肖斌魏潇潇王泽汇廉宝华国网山西省电力公司长治供电公司山西长治046011

随着智能采集系统在电力网络的部署,配电台区安装的智能融合终端能够为拓扑关系识别提供云技术和边缘计算的相关数据。提出了一种基于融合终端识别的配电台区拓扑关系识别方法。首先分析了拓扑识别技术的原理和算法,对比分析了各方法的... 详细信息

随着智能采集系统在电力网络的部署,配电台区安装的智能融合终端能够为拓扑关系识别提供云技术和边缘计算的相关数据。提出了一种基于融合终端识别的配电台区拓扑关系识别方法。首先分析了拓扑识别技术的原理和算法,对比分析了各方法的优缺点,提出了知识图谱、皮尔逊算法和大数据分析的综合识别方法。给出了配电台区拓扑识别的边界条件,说明了本方法的实现步骤。最后以实际算例进行仿真分析,说明了加装带量测剩余电流动作保护器的拓扑识别结果。

关键词：电力大数据配电台区拓扑识别流程分析

全脑SIB-IMRt治疗EGFR野生型或耐药型肺腺癌脑转移瘤的疗效观察及护理体会

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山东医学高等专科学校学报 2024年第4期46卷 1-4页

作者：常瑛刘京丽刘莲花黄丙俭临沂市肿瘤医院山东临沂276034

目的探讨EGFR野生型或耐药型肺腺癌脑转移瘤的治疗及护理方法。方法将46例EGFR野生型或耐药型肺腺癌脑转移瘤患者随机分为两组,各23例。两组均行全脑SIB-IMRt,观察组联合贝伐珠单抗;两组均采用循证护理干预。比较两组临床效果。结果观... 详细信息

目的探讨EGFR野生型或耐药型肺腺癌脑转移瘤的治疗及护理方法。方法将46例EGFR野生型或耐药型肺腺癌脑转移瘤患者随机分为两组,各23例。两组均行全脑SIB-IMRt,观察组联合贝伐珠单抗;两组均采用循证护理干预。比较两组临床效果。结果观察组临床疗效、瘤周水肿体积、健康指数及生活满意度得分改善程度均优于对照组(Pt联合贝伐珠单抗治疗EGFR野生型或耐药型肺腺癌脑转移瘤疗效肯定,安全性好。

关键词：肺腺癌脑转移同期推量调强放疗循证护理

Effect of purine-rich box1 on proliferation of fibroblasts

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1827-1832页

作者： Ke Lu Hai-tao Du Ai-Ling lian ying Su Feng Wang Department of Ophthalmology the First Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina Department of Centric Operating Room the First Affiliated Hospital of Harbin Medical UniversityHarbin 150001Heilongjiang ProvinceChina

Fibroblasts are pleomorphic cells that have a multidirectional effect on organ morphogenesis,tissue homeostasis,and immune *** fibrotic diseases,fibroblasts synthesize large amounts of extracellular matrix(ECM),leading to scarring and organ ***-rich boxl(PU.I)is a specific transcription factor of hematopoietic cell and belongs to the E26 transformation specificity(EtS)***,it was found that the transcription factor PU.I is an important regulatory factor of the profibrotic gene expression ***-J3 had been proved to play an important role in many ocular tissue fibrosis diseases,and up-regulated the expression of PU.I in fibroblasts producing ECM in a Smad-3 dependent *** explore the effect of PU.I on fibrosis of different ocular tissues from this *** article reviews the role of PU.l and its effects on fibrosis of ocular tissue and other tissues.

关键词： purine-rich boxl tGF-P extracellular matrix fibroblasts fibrosis ocular tissue

强直性脊柱炎患者外周血tLR4、JAK3基因表达与th17/treg失衡的关系

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天津医药 2024年第10期52卷 1065-1068页

作者：张志强王威威董腾靖连鸿凯郑州市中心医院骨科 450000

目的探究强直性脊柱炎患者外周血中toll样受体4(tLR4)、Janus蛋白酪氨酸激酶3(JAK3)基因表达与辅助性t细胞17(th17)/调节性t细胞(treg)失衡的关系。方法101例AS患者(AS组)按照AS疾病活动指数(BASDAI)评分分为AS稳定期(ASS)组(<4分)42例... 详细信息

目的探究强直性脊柱炎患者外周血中toll样受体4(tLR4)、Janus蛋白酪氨酸激酶3(JAK3)基因表达与辅助性t细胞17(th17)/调节性t细胞(treg)失衡的关系。方法101例AS患者(AS组)按照AS疾病活动指数(BASDAI)评分分为AS稳定期(ASS)组(tLR4、JAK3 mRNA表达,检测血清th17、treg细胞比例,并计算th17/treg比值。结果AS组外周血PBMC中tLR4 mRNA、JAK3 mRNA表达高于健康组(Pth17比例及th17/treg高于健康组,treg比例低于健康组(PtLR4 mRNA、JAK3 mRNA及th17为AS的危险因素,较高水平treg为AS保护因素。AS患者tLR4 mRNA、JAK3 mRNA分别与th17比例及th17/treg呈正相关,与treg比例呈负相关(PtLR4、JAK3基因呈高表达且th17/treg呈失衡状态,tLR4、JAK3基因高表达与AS患者th17/treg失衡密切相关。

关键词：脊柱炎强直性单核细胞 toll样受体4 Janus激酶3 th17/treg失衡

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