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Strengthening and deformation mechanism of high-strength CrMnFeCoNi high entropy alloy prepared by powder metallurgy

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Journal of Materials Science & technology 2023年第1期132卷 119-131页

作者： y.Xing C.J.Li y.K.Mu y.D.jia K.K.Song J.tan G.Wang Z.Q.Zhang J.H.yi J.Eckert Faculty of Materials Science and Engineering Kunming University of Science and TechnologyKunming 650093China Laboratory for Microstructures Institute of MaterialsShanghai UniversityShanghai 200444China School of Mechanical Electrical&Information EngineeringShandong UniversityWeihai 264209China College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Erich Schmid Institute of Materials Science Austrian Academy of SciencesJahnstraße 12Leoben A-8700Austria Department of Materials Science Chair of Materials PhysicsMontanuniversität LeobenJahnstraße 12Leoben A-8700Austria Adjunct with National University of Science and technology«MISiS» Leninsky Prosp.4Moscow 119049Russia

Multiphase CrMnFeCoNi high-entropy alloys(HEAs)were prepared by a powder metallurgy process com-bining mechanical alloying(MA)and vacuum hot-pressing sintering(HPS).the single-phase face-centered cubic(FCC)HEA powder prepared by MA was sintered into a bulk HEA specimen containing FCC phase matrix along with precipitated M 23 C 6 phase and nanoscaleσphase *** the sintering temper-ature was 1223 K,the ultimate strength reaches 1300±11.6 MPa,and the elongation exceeds 4%±0.6%.Microstructural characterization reveals that the formation of nanoscale particles and deformation twins play critical roles in improving the strain hardening(SH)*** the MA time promoted the formation of the precipitated phase and enhanced the SH ability by increasing the number of precip-itated *** SH capacity increases significantly with increasing sintering temperature,which is attributed to a significant enhancement in the twinning capacity due to grain growth and the reduced number ofσphase *** systematic studies,the planar glide of dislocations was found to be the main mode of deformation,while deformation twinning appeared as an auxiliary deformation mode when the twinning stress was *** the formation of precipitates leads to grain bound-ary and precipitation strengthening effects,crack initiation is more prominent owing to increased grain boundary brittleness around the precipitated M 23 C 6 *** prominence of crack initiation is a contra-diction that must be reconciled with regard to precipitation *** work serves as a useful reference for the preparation of high-strength HEA parts by powder metallurgy.

关键词： High entropy alloy Powder processing Grain reﬁnement Precipitation strengthening Deformation twinning

Genetic association of urokinase-type plasminogen activator gene rs2227564 site polymorphism with sporadic Alzheimer's disease in the Han Chinese population

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Neural Regeneration Research 2012年第30期7卷 2377-2383页

作者： Xuelian Ji Longfei jia jianping jia Li Qi Department of Neurology Inner Mongolia People's Hospital Huhhot 010017 Inner Mongolia Autonomous Region China Department of Neurology Xuanwu Hospital Capital Medical University Beijing 100053 China Inner Mongolia Corps Hospital Chinese People's Armed Police Forces Huhhot 010040 Inner Mongolia Autonomous Region China

A missense C/t polymorphism in exon 6 （the NCBI rslD is rs2227564） of the urokinase-type plasminogen activator gene has been identified as a possible hot spot for Alzheimer＇s disease risk. the present study analyzed urokinase-type plasminogen gene polymorphisms of rs2227564 with sporadic Alzheimer＇s disease by PCR-restriction fragment length polymorphism. Results showed that CC, Ct and tt genotype distribution frequencies had significant differences between sporadic Aizheimer＇s disease patients and healthy controls, in-depth analysis of the association between urokinase-type plasminogen gene rs2227564 polymorphisms and sporadic Alzheimer＇s disease indicated that people with the C-positive genotype CC ＋ Ct were at a higher risk for developing sporadic Alzheimer＇s disease. these results support the contribution of the polymorphisms of rs2227564 in the urokinase-type plasminogen gene to the pathogenesis of sporadicAIzheimer＇s disease in the Han Chinese population.

关键词： Alzheimer's disease urokinase plasminogen activator polymorphism genetic testing Han Chinesepopulation neural regeneration

Suspended particulate and colloidal matter in natural waters

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Journal of Environmental Sciences 2000年第2期12卷 4-12页

作者： Ran, yong Fu, jia-Mo Sheng, Guo-ying Beckett, R. Hart, B.t. State Key Laboratory of Organic Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China Water Studies Center Monash University Caulfield East Vic. 3145 Australia

the association of pollutants (nutrients, heavy metals and organic compounds) with colloidal and suspended particle matter(SPM) plays a dominant role in determining their transport, fate, biogeochemistry, bioavailability and toxicity in natural waters. A scheme for the fractionation and composition of colloidal and suspended particulate matter from river waters has been tested. Sieving, continuous flow centrifugation and tangential flow filtration were used to collect gram amounts of colloidal and particulate matters. the separation scheme was able to process large samples(100L), within reasonable times(1 day) and the apparatus was portable. the aquatic colloid was also separated with high resolution, and sized using sedimentation field\|flow fractionation technique. the mass\|based particle size distribution for the river water sample showed a broad size distribution between 0\^05 and 0\^4 μm with the maximum around 0\^14 μm. there was a systematic increase in the content of organic carbon, Mg, Ca, Na, Cu and Zn with decreasing particle size, highlighting the importance of the colloidal(tion.

关键词： suspended particulate colloidal matter natural waters pollutants CLC number: X132 Document code: A

Optimal time Decay of Navier–Stokes Equations with Low Regularity Initial Data

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Acta Mathematica Sinica,English Series 2018年第5期34卷 855-872页

作者： Jun Xiong jia Department of Mathematics Xi’an Jiaotong University Beijing Center for Mathematics and Information Interdisciplinary Sciences (BCMIIS)

In this paper, we study the optimal time decay rate of isentropic Navier-Stokes equations under the low regularity assumptions about initial data. In the previous works about optimal time decay rate, the initial data need to be small in H^[N/2]＋2（R^N）. Our work combined negative Besov space estimates and the conventional energy estimates in Besov space framework which is developed by Danchim through our methods, we can get optimal time decay rate with initial data just small in B^N/2-1,N/2＋1∩^N/2-1,N/2 and belong to some negative Besov space （need not to be small）. Finally, combining the recent results in [25] with our methods, we only need the initial data to be small in homogeneous Besov space B^N/2-2,N/2 ∩B^N/2-1 to get the optimal time decay rate in space L2.

关键词： Compressible fluids besov space framework optimal time decay negative Besov space

the Impact of Cigarette Smoking on Metabolic Syndrome

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Biomedical and Environmental Sciences 2013年第12期26卷 947-952页

作者： jia Wei Ping Department of Endocrinology and Metabolism Shanghai Jiao Tong University Affiliated Sixth People’s Hospital Shanghai Clinical Center for Diabetes Shanghai Diabetes Institute Shanghai Key Laboratory of Diabetes Mellitus Shanghai Key Clinical Center for Metabolic Disease

Metabolic syndrome （MetS） is a constellation of interconnected cardiometabolic disorders, including obesity, hyperglycemia, dyslipidemia, and elevated blood pressure. MetS is a precursor to type 2 diabetes mellitus （t2DM） and cardiovascular disease （CVD）; it increases the risk of t2DM by 3-4 times[11 and the risk of CVD by 1.4-fold[21, and is more prevalent in obese individuals. As the obesity rates increase, the prevalence of MetS in the population is increased. In 2006, the global prevalence of MetS in adults was estimated to be 20%-25%tM, and in China, in 2007-2008, using the criteria of the Chinese Joint Committee for Developing Chinese Guidelines on Prevention and treatment of Dyslipidemia in Adults （JCDCG）, it reached 21.9% among the adult population aged 〉20 vears old[4].

关键词： the Impact of Cigarette Smoking on Metabolic Syndrome

Regularity of Invariant Sets in Variable Internal Damped Wave Equations

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Acta Mathematicae Applicatae Sinica 2020年第4期36卷 952-974页

作者： Gao-cheng yUE yu-xin LIANG jia-jia yANG Department of Mathematics Nanjing University of Aeronautics and AstronauticsNanjing 211106China

In this paper we prove that every compact invariant subset■associated with the semigroup{Sn,k(t)}t≥0 generated by wave equations with variable damping,either in the interior or on the boundary of the domainΩwhereΩ■R^3 is a smooth bounded domain,in H^10(Ω)×L^2(Ω)is in fact bounded in D(B0)×H^10(Ω)As an application of our results,we obtain the upper-semicontinuity for global attractor of the weakly damped semilinear wave equation in the norm of H^1(Ω)×L^2(Ω)when the interior variable damping converges to theboundary damping in the sense of distributions.

关键词： Damped wave equation boundary damping invariant set regularity

New multi-color photometric investigations of solar-like contact binary V680 Per

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Research in Astronomy and Astrophysics 2020年第4期20卷 49-56页

作者： Jing-Jing Wang jia-jia He Song-Qing Zhao China University of Petroleum–Beijing at Karamay Karamay 834000China yunnan Observatories Chinese Academy of SciencesKunming 650216China Key Laboratory of the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China

High-precision CCD photometric observations of the contact binary V680 Per were obtained *** symmetric multi-color light curves were analyzed by using the Wilson–Devinney(2013)*** photometric solutions suggest that V680 Per is an A-type W UMa contact binary with the mass ratio of q=0.693 and a fill-out factor of f=18.84%with a small temperature difference of 101 *** on all minimum times,the O-C curve was analyzed for the first time in this study.A cyclic oscillation(A3=0.00093 d,t3=4.92 yr)superimposed on a secular decrease(d P/dt=-8.16×10-8 d yr-1)was *** continuous decrease in period is possibly a result of mass transfer from the more massive component to the less massive one,or angular momentum loss due to a magnetic stellar *** of this secular decrease,it is predicted that the degree of contact will become higher,and V680 Per will evolve into a deeper overcontact binary.

关键词： binaries:eclipsing stars:solar-type stars:individual(V680 Per)

temporal and spatial regulation of biomimetic vascularization in 3D-printed skeletal muscles

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Bio-Design and Manufacturing 2024年第5期7卷 597-610页

作者： Minxuan jia tingting Fan tan jia Xin Liu Heng Liu Qi Gu Key Laboratory of Organ Regeneration and Reconstruction State Key Laboratory of Membrane BiologyInstitute of ZoologyChinese Academy of SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Stem Cell and Reproductive Biology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Department of Orthopaedics Beijing Jishuitan HospitalCapital Medical UniversityBeijing 100035China

In the intricate skeletal muscle tissue,the symbiotic relationship between myotubes and their supporting vasculature is pivotal in delivering essential oxygen and *** study explored the complex interplay between skeletal muscle and endothelial cells in the vascularization ofmuscle *** harnessing the capabilities of three-dimensional(3D)bioprinting and modeling,we developed a novel approach involving the co-construction of endothelial and muscle cells,followed by their subsequent *** findings highlight the importance of the interaction dynamics between these two cell ***,introducing endothelial cells during the advanced phases of muscle differentiation enhanced myotube ***,it stimulated the development of the vascular network,paving the way for the early stages of vascularized skeletal muscle *** methodology proposed in this study indicates the potential for constructing large-scale,physiologically aligned skeletal ***,it highlights the need for exploring the delicate equilibrium and mutual interactions between muscle and endothelial *** on the multicell-type interaction model,we can predict promising pathways for constructing even more intricate tissues or organs.

关键词： Skeletal muscle Vascularization 3D bioprinting Cell interaction

New discoveries in obesity and related metabolic diseases:from bench to bed

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Journal of Molecular Cell Biology 2021年第8期13卷 541-542页

作者： Weiping jia Department of Endocrinology and Metabolism Shanghai Diabetes InstituteShanghai Key Laboratory of Diabetes MellitusShanghai Clinical Center for DiabetesShanghai Key Clinical Center for Metabolic DiseaseShanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghai 200233China

Obesity,and other metabolic diseases including non-alcoholic fatty liver disease(NAFLD),metabolic syndrome(MetS),type 2 diabetes mellitus(t2DM)and its related complications like chronic kidney disease(CKD),and hepatocellular carcinoma(HCC)have led to alarming health and social burdens globally and in China as *** strong links exist among those multifactorial metabolic disorders,there are limited researches on better understanding of their pathogenesis and the provision of effective interventional measures in *** this special issue,we have five researches including three research articles providing new insights into potential mechanisms in the development and possible prevention and treatment therapies of NAFLD,HCC,and CKD,as well as two review articles summarizing multi-omics profiling and future strategies for precision medicine in t2DM,NAFLD,and MetS,and the rapid advances in the field of metabolic surgery in China.

关键词： diseases prevention obesity