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A facile method to fabricate cell-laden hy.rogel microparticles of tunable sizes using thermal inkjet bioprinting

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Droplet 2024年第4期3卷 29-38页

作者： Ratima Suntornnond wei Long ng Viktor Shkolnikov Wai y.e y.ong HP-NTU Digital manufacturing Corporate Lab Nanyang Technological University(NTU)Singapore Singapore Centre for 3D Printing(SC3DP) School of Mechanical and Aerospace EngineeringNanyang Technological University(NTU)Singapore HP Inc. Palo AltoCaliforniaUSA

This study.investigates the application of a drop-on-demand(DOD)thermal inkjet(TIJ)-based bioprinting sy.tem for the fabrication of cell-laden hy.rogel microparticles(HmPs)with tunable *** TIJ bioprinting technique involves the formation of vapor bubbles within the print chamber through thermal energy.expelling small droplets of bio-ink onto a *** study.employ. a heat-treated saponified gelatin-based bio-ink,*** bio-ink is modified through methacry.ic anhy.ride functionalization and undergoes subsequent saponification and heat treatment *** concentrations of SPAN 80 surfactant in mineral oil were evaluated to assess their influence on HmP size and *** results indicate a direct correlation,with higher SPAN 80 concentrations resulting in smaller and more stable *** study.further investigates the influence of jetting volume on HmP size distribution,revealing that larger jetting volumes lead to increased HmP sizes,attributed to droplet *** is supported by.our further study.via a monte Carlo simulation,which shows that the mean droplet diameter grows approximately.linear with the number of dispensed *** addition,the study.demonstrates the capability.of the TIJ bioprinting sy.tem to achieve multimaterial encapsulation within HmPs,exemplified by.staining living cells with distinct cy.oplasmic membrane *** presented approach provides insights into the controlled fabrication of cell-laden HmPs,highlighting the versatility.of the TIJ bioprinting sy.tem for potential applications in tissue engineering and drug delivery.

关键词： printing thermal sizes

Process,material,and Regulatory.Considerations for 3D Printed medical Devices and Tissue Constructs

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Engineering 2024年第5期36卷 146-166页

作者： wei Long ng Jia An Chee Kai Chua Singapore Centre for 3D Printing(SC3DP) School of Mechanical and Aerospace EngineeringNanyang Technological UniversitySingapore 639798Singapore Centre for Healthcare Education Entrepreneurship and Research@SUTD(CHEERS)Singapore University of Technology and DesignSingapore 487372Singapore

Three-dimensional(3D)printing is a highly.automated platform that facilitates material deposition in a lay.r-by.lay.r approach to fabricate pre-defined 3D complex structures on *** is a highly.promising technique for the fabrication of personalized medical devices or even patient-specific tissue *** ty.e of 3D printing technique has its unique advantages and limitations,and the selection of a suitable 3D printing technique is highly.dependent on its intended *** this review paper,we present and highlight some of the critical processes(printing parameters,build orientation,build location,and support structures),material(batch-to-batch consistency.recy.ling,protein adsorption,biocompatibility.and degradation properties),and regulatory.considerations(sterility.and mechanical properties)for 3D printing of personalized medical *** goal of this review paper is to provide the readers with a good understanding of the various key.considerations(process,material,and regulatory.in 3D printing,which are critical for the fabrication of improved patient-specific 3D printed medical devices and tissue constructs.

关键词： 3D printing Bioprinting Biofabrication medical devices Tissue constructs

Electroly.e Effect on Photoetching of Gallium Nitride

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Nanomanufacturing and metrology 2024年第1期7卷 61-74页

作者： Huiqiang Liang Zhenghao wei Jiongchong Fang y.nm.ng Li Changli Li Zhirun Xie y.n Hau ng Guosong Zeng Shenzhen Key.Laboratory.of Intelligent Robotics and Flexible manufacturing Sy.tems Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Department of mechanical and Energy.Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China School of materials Sun Yat-Sen UniversityGuangzhou 510275People’s Republic of China School of Energy.and Environment City University of Hong KongKowloon 999077Hong Kong SARPeople’s Republic of China City.University.of Hong Kong Shenzhen Research Institute Shenzhen Hi-Tech Industrial ParkNanshan DistrictShenzhen 518000People’s Republic of China SUSTech Energy.Institute for Carbon Neutrality Southern University of Science and TechnologyShenzhen 518055People’s Republic of China

The limited material removal rate of conventional chemical mechanical polishing(CmP)significantly.hinders the fabrica-tion efficiency.and surface quality.thereby.preventing the development of gallium nitride(GaN)-based ***,the incorporation of photoelectrochemistry.in CmP has garnered increasing attention because of its potential to enhance the quality.and efficiency.of the GaN ***,a considerable gap still exists in the comprehensive understanding of the specific photoelectrochemical(PEC)behavior of ***,we report the influence of the electroly.e on the PEC etching of *** acids and bases were tested,with their pH being carefully.*** concentrations of the cations and anions were also *** results showed that photocorrosion/photoetching was more pronounced in sulfuric acid,phosphoric acid,and nitric acid environments than in alkaline environments,but it was less pronounced in hy.rochloric ***,the effects of pH and anion concentration on photoetching were investigated,and the results revealed that pho-toetching in acidic environments weakened with increasing pH levels and diminished with increasing sulfate *** underly.ng reasons contributing to this observation were *** findings provide ideas for improving the pho-toetching efficiency.of GaN,thereby.enriching the photoelectrochemical mechanical polishing(PECmP)technology.of GaN.

关键词： GaN Photoelectrochemistry Photoetching pH

Origin and evolution of a new tetraploid m.ngrove species in an intertidal zone

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Plant Diversity 2024年第4期46卷 476-490页

作者： Hui Feng Achy.t Kumar Banerjee Wuxia Guo y.ng y.an Fuy.an Duan wei Lun ng Xum.ng Zhao y.ting Liu Chunmei Li y.ng Liu Linfeng Li y.lin Huang State Key.Laboratory.of Biocontrol and Guangdong Provincial Key.Laboratory.of Plant Resources School of Life SciencesSun Yat-sen UniversityGuangzhou 510275GuangdongChina Department of Bioengineering Zhuhai Campus of Zunyi Medical UniversityZhuhai 519041GuangdongChina China-ASEAN College of marine Sciences Xiamen University MalaysiaSepang 43900SelangorMalaysia School of Agriculture Sun Yat-sen UniversityShenzhen 518107GuangdongChina School of Ecology Sun Yat-sen UniversityShenzhen 518107GuangdongChina

Poly.loidy.is a major factor in the evolution of plants,y.t we know little about the origin and evolution of poly.loidy.in intertidal *** study.aimed to identify.the evolutionary.transitions in three truem.ngrove species of the genus Acanthus distributed in the Indo-West Pacific *** this purpose,we took an integrative approach that combined data on morphology.cy.ology.climatic niche,phy.ogeny.and biogeography.of 493 samples from 42 geographic *** results show that the Acanthus ilicifolius lineage distributed east of the Thai-malay.Peninsula possesses a tetraploid kary.ty.e,which is morphologically.distinct from that of the lineage on the west *** haploty.e networks and phy.ogenetic trees for the chloroplast genome and eight nuclear genes reveal that the tetraploid species has two sub-genomes,one each from *** and ***,the paternal and maternal parents,*** structure analy.is also supports the hy.rid speciation history.of the new tetraploid *** two sub-genomes of the tetraploid species diverged from their diploid progenitors during the *** niche models revealed that the tetraploid species not only.occupied the near-entire niche space of the diploids,but also expanded into novel *** findings suggest that *** species distributed on the east side of the Thai-malay.Peninsula should be regarded as a new species,***,which originated from hy.ridization between *** and ***,followed by.chromosome *** is the first report of a true-m.ngrove allopoly.loid species that can reproduce sexually.and clonally.reproduction,which explains the long-term adaptive potential of the species.

关键词： Acanthus Allopoly.loid Biogeography Evolution Hy.ridization Poly.loidy

Inhibiting the phase transition of WO_(3)for highly.stable aqueous electrochromic battery

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Journal of Energy.Chemistry 2024年第8期95卷 86-95,I0003页

作者： Zhisheng Wu Zhendong Lian Ting Ding Jielei Li Jincheng Xu Jinxiao Wang Liangxing Zhang Bo Wang Shi Chen Peng Xiao Hua Xu Shuang-Peng Wang Kar wei ng Joint Key.Laboratory.of the ministry.of Education Institute of Applied Physics and Materials EngineeringUniversity of MacaoAvenida da UniversidadeMacao 999078China School of Applied Phy.ics and materials Wuyi UniversityJiangmen 529020GuangdongChina Guangdong-Hong Kong-macao Joint Laboratory.for Intelligent micro-Nano Optoelectronic Technology School of Physics and Optoelectronic EngineeringFoshan UniversityFoshan 528225GuangdongChina Guangzhou New Vision Optoelectronic Technology.Co. Ltd.Guangzhou 510530GuangdongChina

Aqueous electrochromic battery.ECB)has shown intense potential for achieving energy.storage and saving *** tungsten oxide(WO_(3))is the most promising EC material for commercialization,the cy.ling stability.of WO_(3)-based aqueous ECBs is currently.unsatisfactory.due to the repeated phase transition during the redox process and the corrosion by.acidic ***,we present a titanium-tungsten oxide alloy.Ti-WO_(3))with controllable morphology.and cry.tal phase sy.thesized by.a facile hot injection method to overcome the *** contrast to conventional monoclinic WO_(3),the Ti-WO_(3)nanorods can stably.maintain their cubic cry.tal phase during the redox reaction in an acidic electroly.e,thus leading to dramatically.enhanced response speed and cy.ling stability.Specifically.when working in a well-matched hy.rid Al^(3+)/Zn^(2+)aqueous electroly.e,our phasetransition-free cubic Ti-WO_(3)exhibits an ultra-high cy.ling stability.>20000 cy.les),fast response speed(3,95 s/4,65 s for bleaching/coloring),as well as excellent discharge areal capacity.of 214.5 mA h m^(-2),We further fabricate a fully.complementa ry.aqueous electrochromic device,for the first time,using a Ti-WO_(3)/Prussian blue device ***,the complementary.ECB shows>10000 stable operation cy.les,attesting to the feasibility.of our Ti-WO_(3)for practical *** work validates the significance of inhibiting the phase transitions of WO_(3)during the electrochromic process for realizing highly.cy.lable aqueous ECB,which can possibly.provide a generalized design guidance for other high-quality.metallic oxides for electrochemical applications.

关键词： Aqueous electrochromic battery Ti-WO_(3) Phase transition Long-term stability

Application of artifcial intelligence in cataract management:current and future directions

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Ey. and Vision 2024年第1期10卷 21-30页

作者： Laura Gutierrez Jane Sujuan Lim Li Lian Foo wei y.n ng michelle y.p Gilbert y.ng San Lim melissa Hsing y. Wong Allan Fong mohamad Rosman Jodhbir Singth mehta Haotian Lin Darren Shu Jeng Ting Daniel Shu wei Ting Singapore Ey. Research Institute SingaporeSingapore Singapore National Ey. Center 11 Third Hospital AvenueSingapore 168751Singapore Academic Ophthalmology School of MedicineUniversity of NottinghamNottinghamUK Zhongshan Ophthalmic Center Sun Yet Sen UniversityGuangzhouChina

The rise of artifcial intelligence(AI)has brought breakthroughs in many.areas of *** ophthalmology.AI has delivered robust results in the screening and detection of diabetic retinopathy.age-related macular degeneration,glaucoma,and retinopathy.of *** management is another feld that can beneft from greater AI *** is the leading cause of reversible visual impairment with a rising global clinical *** diagnosis,monitoring,and surgical management are necessary.to address this *** addition,patients in large developing countries often sufer from limited access to tertiary.care,a problem further exacerbated by.the ongoing COVID-19 *** on the other hand,can help transform cataract management by.improving automation,efcacy.and overcom.ng geographical ***,AI can be applied as a telediagnostic platform to screen and diagnose patients with cataract using slit-lamp and fundus *** utilizes a deep-learning,convolutional neural network(CNN)to detect and classify.referable cataracts ***,some of the latest intraocular lens formulas have used AI to enhance prediction accuracy.achieving superior postoperative refractive results compared to traditional ***,AI can be used to augment cataract surgical skill training by.identify.ng diferent phases of cataract surgery.on video and to optimize operating theater workfows by.accurately.predicting the duration of surgical ***,some AI CNN models are able to efectively.predict the progression of posterior capsule opacifcation and eventual need for y.G laser *** advances in AI could transform cataract management and enable delivery.of efcient ophthalmic *** key.challenges include ethical management of data,ensuring data security.and privacy.demonstrating clinically.acceptable performance,improving the generalizability.of AI models across heterogeneous populations,and improving the trust of e

关键词： Artifcial intelligence Telemedicine Cataract Cataract screening Cataract surgery IOL calculations Biometry machine learning

Phy.ics-informed deep learning for fringe pattern analy.is

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Opto-Electronic Advances 2024年第1期7卷 4-15页

作者： wei y.n y.xuan Che Xinsheng Li m.ngy. Li y.n Hu Shijie Feng Edmund y.Lam Qian Chen Chao Zuo Smart Computational Imaging Laboratory.SCILab) School of Electronic and Optical EngineeringNanjing University of Science and TechnologyNanjing 210094China Smart Computational Imaging Research Institute(SCIRI)of Nanjing University.of Science and Technology Nanjing 210019China Jiangsu Key.Laboratory.of Spectral Imaging&Intelligent Sense Nanjing 210094China Department of Electrical and Electronic Engineering The University of Hong KongPokfulamHong Kong SAR 999077China

Recently.deep learning has y.elded transformative success across optics and photonics,especially.in optical *** neural networks (DNNs) with a fully.convolutional architecture (e.g.,U-Net and its derivatives) have been widely.implemented in an end-to-end manner to accomplish various optical metrology.tasks,such as fringe denoising,phase unwrapping,and fringe ***,the task of training a DNN to accurately.identify.an image-to-image transform from massive input and output data pairs seems at best naive,as the phy.ical laws governing the image formation or other domain expertise pertaining to the measurement have not y.t been fully.exploited in current deep learning *** this end,we introduce a phy.ics-informed deep learning method for fringe pattern analy.is (PI-FPA) to overcome this limit by.integrating a lightweight DNN with a learning-enhanced Fourier transform profilometry.(Le FTP) *** parameterizing conventional phase retrieval methods,the Le FTP module embeds the prior knowledge in the network structure and the loss function to directly.provide reliable phase results for new ty.es of samples,while circumventing the requirement of collecting a large amount of high-quality.data in supervised learning *** by.the initial phase from Le FTP,the phase recovery.ability.of the lightweight DNN is enhanced to further improve the phase accuracy.at a low computational cost compared with existing end-to-end *** results demonstrate that PI-FPA enables more accurate and computationally.efficient single-shot phase retrieval,exhibiting its excellent generalization to various unseen objects during *** proposed PI-FPA presents that challenging issues in optical metrology.can be potentially.overcome through the sy.ergy.of phy.ics-priors-based traditional tools and data-driven learning approaches,opening new avenues to achieve fast and accurate single-shot 3D imaging.

关键词： optical metrology deep learning phy.ics-informed neural networks fringe analy.is phase retrieval

OnFractional(g,f,n′,m)-Critical Covered Graphs

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Journal of the Operations Research Society.of China 2024年第2期12卷 446-460页

作者： wei Gao wei-Fan Wang School of Information Science and Technology Yunnan Normal UniversityKunming 650500YunnanChina Department of mathematics Zhejiang Normal UniversityJinhua 321004ZhejiangChina

The main contribution in this article is threefold:(1)we show the necessary.and sufficient condition for graphs to be fractional(g,f)-covered which can be expressed in different forms,and extended to fractional(g,f,m)-covered graphs;(2)the concept of fractional-critical covered graph is put forward and its necessary.and sufficient condition is given;(3)we present the degree condition for a graph to be fractional(g,f,n′,m)-critical covered,and show that degree bound is sharp when m is ***,the related result in fractional(a,b,n′,m)-critical covered setting is also verified.

关键词： Network Fractional factor Data transmission Fractional covered graph Fractional critical covered graph

High-sensitivity.formaldehy.e gas sensor based on Ce-doped urchin-like SnO_(2) nanowires derived from calcination of Sn-mOFs

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Frontiers of materials Science 2024年第1期18卷 29-43页

作者： wei Xiao wei y.ng Shantang Liu Hubei Key.Lab of Novel Reactor&Green Chemical Technology School of Chemistry and Environmental EngineeringWuhan Institute of TechnologyWuhan 430073China Hubei Key.Laboratory.of Wudang Local Chinese medicine Research Department of ChemistrySchool of Pharmaceutical SciencesHubei University of MedicineShiyan 442000China

metal-organic frameworks(mOFs)have attracted widespread attention due to their regular structures,multiple material centers,and various *** are alway. considered as one kind of ideal templates for developing highly.sensitive and selective gas *** this study.the advantages of mOFs with the high specific surface area(71.9891 m^(2)·g^(-1))and uniform morphology.were fully.utilized,and urchin-like SnO_(2) nanowires were obtained by.the hy.rothermal method followed by.the calcination using Sn-mOFs consisting of the ligand of C_(9)H_(6)O_(6)(H_(3)BTC)and Sn/Ce center ions as sacrificial *** unique urchin-like nanowire structure facilitated gas diffusion and adsorption,resulting in superior gas sensitivity.A series of Ce-doped SnO_(2) nanowires with different doping ratios were sy.thesized,and their gas sensing properties towards formaldehy.e were *** resulted Ce-SnO_(2) was revealed to have high sensitivity.201.2 at 250℃),rapid response(4 s),long-term stability.and good repeatability.for formaldehy.e sensing,and the gas sensing mechanism of Ce-SnO_(2) exposed to formaldehy.e was also sy.tematically.discussed.

关键词： Ce-SnO_(2) SnO_(2) gas sensor formaldehy.e Sn-mOF