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Effective roles of exercise and diet adherence in non-alcoholic fatty.liver disease

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World Journal of Gastroenterology 2024年第29期30卷 3456-3460页

作者： Wei zhu School of Life Sciences and Technology Tongji UniversityShanghai 200092China Shanghai Xirong Information Science and Technology.Co. Ltd.National Science and Technology ParkTongji UniversityShanghai 200092China

Non-alcoholic fatty.liver disease(NAFLD)is characterized by.sy.ptoms of excessive fat accumulation and steatosis in the liver without alcohol intake in *** associated pathogenic mechanism is not completely.understood and there are no specific drugs for patients with *** and diet adherence are the best options for the management of NAFLD *** associated analy.is models of adherence to these interventions are used to assess their effectiveness in the management of NAFLD patients using specificity.sensitivity.and so *** have indicated that the relative ratio of NAFLD can be reduced by.phy.ical activity.with diet *** the future,the pathogenesis of NAFLD should be clarified with stratified efforts to develop appropriate drugs,and both exercise and diet adherence should be optimized using better questionnaire design and evaluation models for patients with NAFLD.

关键词： Exercise and diet adherence Non-alcoholic fatty.liver disease Delphi Mediterranean diet Phy.ical lifesty.e

Effect of confining pressure on rock breaking by.high-pressure waterjet-assisted TBM

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Underground Space 2024年第5期18卷 151-161页

作者： Chen Xu y.jie zhu Xiaoli Liu Fei Chen Min zhu Enzhi Wang Sijing Wang School of Resource and Environment Engineering Wuhan University of TechnologyWuhan 430070China Changjiang Institute of Survey PlanningDesign and ResearchWuhan 430010China State Key.Laboratory.of Hy.roscience and Engineering Tsinghua UniversityBeijing 100084China Key.Laboratory.of Geotechnical Mechanics and Engineering of Ministry.of Water Resources Wuhan 430010China

High-pressure waterjet-assisted tunnel boring machine(WTBM)is an efficient method for improving the tunneling performance of a tunnel boring machine(TBM)and reducing the wear of its disc cutters in hard rock with high *** pressure directly.affects the efficiency.of rock breaking and the configuration of the disc *** this study.we evaluated the effect of confining pressure on WTBM rock breaking by.developing a self-designed and manufactured experimental sy.tem,including confining pressure loading,TBM disc-cutter penetration,and high-pressure *** macro fracture,acoustic emission(AE),peak normal force drop,and specific energy.SE)were analy.ed for four different confining pressures(10,20,30,and 35 MPa).The results showed that the cutting depth of the waterjet increased linearly.as the waterjet pressure increased and decreased with the gradual increase in the nozzle moving *** expansion and development of cracks formed rock debris,and the size of the rock fragments decreased with an increase in confining *** the waterjet pressure was 280 MPa,the nozzle moving velocity.was 800 mm/min and the kerf space was 75 mm,which indicated that the confining pressure,which was 23.16 MPa,minimized the cutting SE under this ***,regardless of the confining pressure,the maximum normal force of WTBM was less than that of a TBM,whereas the SE of WTBM was less than that of complete TBM cutting mode(CTCM).The average force drop and average drop rate of SE were approximately.25%,and 80%,*** results of this study.can inspire the design and mechanism of a TBM assisted by.a high-pressure waterjet.

关键词： Waterjet Tunnel boring machine(TBM) Confining pressure Specific energy Force drop

Exhaustive review of acceleration strategies for Monte Carlo simulations in photon transit

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 5-21页

作者： Louzhe Xu Zijie zhu Ting Li Institute of Biomedical Engineering Chinese Academy.of Medical Sciences&Peking Union Medical College Tianjin 300192 P.R.China

Monte Carlo simulation techniques have become the quintessence and a pivotal nexus of inquiry.in the realm of simulating photon movement within biological *** the stochastic sampling of tissue archety.es delineated by.explicit optical characteristics,Monte Carlo simulations possess the theoretical capacity.to render unparalleled accuracy.in the depiction of exceedingly.intricate ***,the quintessential challenge associated with Monte Carlo simulation methodologies resides in their extended computational duration,which significantly.impedes the re¯nement of their ***,this discourse is speci¯cally.dedicated to exploring innovations in strategies and technologies aimed at expediting Monte Carlo *** delves into the foundational concepts of various acceleration tactics,evaluates these strategies concerning their speed,accuracy.and practicality.and amalgamates a comprehensive overview and critique of acceleration methodologies for Monte Carlo ***,the discourse envisages prospective trajectories for the employ.ent of Monte Carlo techniques within the domain of tissue optics.

关键词： Medical optics photon transport simulation Monte Carlo simulation acceleration

Chemoselective epoxidation of electron-deficient olefins with molecular oxy.en via conjugated olefins epoxidation and BHT hy.roxy.ation

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Science China Chemistry 2024年第9期67卷 3012-3018页

作者： Jia Nie Huanfeng Jiang Chuanle zhu School of Chemistry.and Chemical Engineering Key Lab of Functional Molecular Engineering of Guangdong ProvinceSouth China University of TechnologyGuangzhou 510640China Guangdong Provincial Key.Laboratory.of Technique and Equipment for Macromolecular Advanced Manufacturing South China University of TechnologyGuangzhou 510640China

The chemoselective epoxidation of electron-deficient olefins in the presence of electron-rich alkene moieties is *** chemoselective epoxidation strategy.undergoes a conjugated olefin epoxidation and BHT hy.roxy.ation process to give various useful oxiranes in high y.elds,especially.for the 2-substituted ***,this protocol features mild conditions,is transition-metal free,operationally.simple,and gram-scalable,and tolerates diverse functional *** candidate HSD-16 is sy.thesized smoothly.by.this *** studies indicate molecular oxy.en is the terminal oxidant and the O-source of the oxiranes.

关键词： chemoselective epoxidation alkene fluorine molecular oxy.en

The effect of glutathione on glucosinolate biosy.thesis through the sulfur assimilation pathway.in pakchoi associated with the growth conditions

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Horticultural Plant Journal 2024年第2期10卷 473-487页

作者： Biao zhu Zhile Liang Dan Wang Chaochao He zhujun zhu Jing y.ng Key.Laboratory.of Quality.and Safety.Control for Subtropical Fruit and Vegetable Ministry of Agriculture and Rural AffairsCollaborative Innovation Center for Efficient and Green Production of Agriculture in Mountainous Areas of Zhejiang ProvinceCollege of Horticulture ScienceZhejiang A&F UniversityHangzhouZhejiang 311300China

Glucosinolates(GSLs) are a group of nitrogen-and sulfur-containing secondary.metabolites, sy.thesized primarily.in members of the Brassicaceae family. that play.an important role in food flavor, plant antimicrobial activity. resistance to insect attack, stress tolerance, and human anti-cancer effects. As a sulfur-containing compound, glutathione has a strong connection with GSLs biosy.thesis as a sulfur donor or redox sy.tem, and exists in reduced(glutathione;GSH) and oxidized(glutathione disulfide;GSSG) forms. However, the mechanism of GSH regulating GSLs biosy.thesis remainds unclear. Hence, the exogenous therapy.to pakchoi under normal growth condition and sulfur deficiency.condition were conducted in this work to explore the relevant mechanism. The results showed that exogenous application of buthionine sulfoximine, an inhibitor of GSH sy.thesis, decreased the transcript levels of GSLs sy.thesis-related genes and transcription factors, as well as sulfur assimilation-related genes under the normal growth condition. Application of exogenous GSH inhibited the expression of GSLs sy.thesis-and sulfur assimilation-related genes under the normal condition, while the GSLs biosy.thesis and the sulfur assimilation pathway.were activated by.exogenous application of GSH when the content of GSH in vivo of plants decreased owing to sulfur deficiency. Moreover,exogenous application of GSSG increased the transcript levels of GSLs sy.thesis-and sulfur assimilation-related genes under the normal growth condition and under sulfur deficiency. The present work provides new insights into the molecular mechanisms of GSLs biosy.thesis underly.ng glutathione regulation.

关键词： Pakchoi Glucosinolates Reduced glutathione Oxidized glutathione Sulfur assimilation

Contribution of high-latitude permafrost regions in the Northern Hemisphere to global wildfire carbon emissions

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Science China Earth Sciences 2024年第10期67卷 3239-3251页

作者： Xingru zhu Xiy.n XU Gensuo JIA Key.Laboratory.of Regional Climate-Environment for East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary.Sciences University of Chinese Academy of SciencesBeijing 100049China

Wildfires are major disturbances in permafrost ecosy.tems, with increasing frequency.and intensity.in recent y.ars. In permafrost regions, wildfires not only.burn surface and subsurface organic matter but also accelerate permafrost thawing,releasing significant amounts of greenhouse gases such as carbon dioxide and methane into the atmosphere. However, the contribution of high-latitude permafrost regions in the Northern Hemisphere to global wildfire carbon emissions remains poorly.understood. This study.integrates remote sensing data and ground observations to analy.e the contributions of aboveground and belowground fuel combustion in high-latitude permafrost regions to global wildfire carbon emissions from 2002 to 2020, as well as the spatiotemporal variations in these contributions. Our findings indicate that permafrost regions contribute approximately.1.96% of global wildfire carbon emissions, with aboveground emissions accounting for approximately.3.94% of global aboveground emissions and belowground emissions contributing approximately.63.57% of global belowground emissions. The contribution of high-latitude permafrost regions to global emissions peaked in July.and August, whereas the continuous permafrost zones(areas with more than 90% permafrost coverage) showed the most significant increase in June and July. The contributions of both aboveground and belowground emissions from high-latitude permafrost regions to global wildfire emissions have been increasing, primarily.due to the reduction in global wildfire emissions, in contrast with the rising emissions from wildfires in high-latitude permafrost regions. This study.highlights the significant role of wildfires, particularly.the combustion of belowground biomass in high-latitude permafrost regions, in global carbon emissions. The decomposition and combustion of organic carbon in permafrost regions due to wildfires release more greenhouse gases into the atmosphere, potentially.amplify.ng the positive feedback

关键词： Wildfire Permafrost Carbon emissions Climate change Belowground fuel consumption

Design strategies and recent advancements of solid-state supercapacitor operating in wide temperature range

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Carbon Energy 2024年第6期6卷 248-281页

作者： Jie Zhou Zhengfeng zhu Wenhui Shi Xiangy. Shi zhuoy.an Zheng y. Xiong y.song zhu School of Energy.Science and Engineering Nanjing Tech UniversityNanjingJiangsuChina Kucap Smart Technology.Nanjing)Co. Ltd.NanjingJiangsuChina

Solid-state supercapacitors(SSCs)are emerging as one of the promising energy.storage devices due to their high safety.superior power density.and excellent cy.ling ***,performance degradation and safety.issues under extreme conditions are the main challenges for the practical *** the expansion of human activities,such as space missions,polar exploration,and so on,the investigation of SSC with wide temperature tolerance,high energy.density.power density.and sustainability.is highly.*** this review,the effects of temperature on SSC are sy.tematically.illustrated and clarified,including the properties of the electroly.e,ion diffusion,and reaction dy.amics of the ***,we summarize the recent advances in wide-temperature-range SSCs from the aspect of electroly.e modification,electrode design,and interface adjustment between electrode and electroly.e,especially.with critical concerns on ionic conductivity.and cy.ling *** the end,a perspective is presented,expecting to promote the practical application of the SSC in harsh conditions.

关键词： electrode interface solid-state electroly.e solid-state supercapacitor wide temperature

Camera,LiDAR,and IMU Based Multi-Sensor Fusion SLAM:A Survey

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Tsinghua Science and Technology 2024年第2期29卷 415-429页

作者： Jun zhu Hongy. Li Tao Zhang Department of Automation Tsinghua UniversityBeijing 100084China

In recent y.ars,Simultaneous Localization And Mapping(SLAM)technology.has prevailed in a wide range of applications,such as autonomous driving,intelligent robots,Augmented Reality.AR),and Virtual Reality.VR).Multi-sensor fusion using the most popular three ty.es of sensors(e.g.,visual sensor,LiDAR sensor,and IMU)is becoming ubiquitous in SLAM,in part because of the complementary.sensing capabilities and the inevitable shortages(e.g.,low precision and long-term drift)of the stand-alone sensor in challenging *** this article,we survey.thoroughly.the research efforts taken in this field and strive to provide a concise but complete review of the related ***,a brief introduction of the state estimator formation in SLAM is ***,the state-of-the-art algorithms of different multi-sensor fusion algorithms are *** we analy.e the deficiencies associated with the reviewed approaches and formulate some future research *** paper can be considered as a brief guide to newcomers and a comprehensive reference for experienced researchers and engineers to explore new interesting orientations.

关键词： multi-sensor fusion Simultaneous Localization And Mapping(SLAM) navigation localization

The Effect of Moisture in Different Altitude Lay.rs on the Eastward Propagation of MJO

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Journal of Meteorological Research 2024年第3期38卷 437-452页

作者： Xiaoy. zhu Zhong ZHONG y.min zhu y.ny.ng LI y.jia HU y.o HA College of Meteorology.and Oceanography National University of Defense TechnologyChangsha410000China Key.Laboratory.for Virtual Geographic Environment School of Geography ScienceNanjing Normal UniversityNanjing210023China Jiangsu Collaborative Innovation Center for Climate Change School of Atmospheric SciencesNanjing UniversityNanjing210000China

In this study.driven by.ERA5 reanaly.is data,the Weather Research and Forecasting(WRF)version 4.0 was used to investigate the eastward propagation of the Madden-Julian oscillation(MJO)in the tropical atmosphere during December-February.DJF)of 2007/*** experiment with 11 cumulus parameterization schemes respectively.shows that the Grell 3D scheme is one of several worse ones in describing MJO *** addition,still by.use of the Grell 3D scheme,four nudging assimilation experiments for water vapor in all model vertical lay.rs(Ndg_all),lower lay.rs(Ndg_low),middle lay.rs(Ndg_mid),and upper lay.rs(Ndg_upp)were *** is found that when the water vapor in the model approaches to the observed value,the model performance for MJO activities is improved *** the four nudging simulations,Ndg_all certainly.performs *** Ndg_mid is important for the MJO-filtered profiles related to moisture,Ndg_low and Ndg_upp exhibit superiority.to Ndg_mid in simulating MJO eastward ***_low has advantages when MJO features are represented by.zonal wind at 850 hPa and precipitation because the lower-level MJO-filtered moisture is conducive to the existence of lower-level condensational heating to the east of the MJO convective ***_upp performs better when describing the MJO eastward propagation features by.outgoing longwave radiation(OLR)since it can capture the moisture and cloud top temperature of deep convection associated with MJO,as well as front Walker *** results suggest that the lower-level moisture is more important in regulating the MJO eastward propagation,and the observed maximum MJO-filtered moisture in the middle troposphere might be a phenomenon accompany.ng the MJO deep convection,but not a factor controlling its eastward propagation.

关键词： Madden-Julian oscillation(MJO) nudging technique Weather Research and Forecasting(WRF)model vertical moisture structure