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Status of biomarker development for frontotemporal dementia and amy.trophic lateral sclerosis

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Neural Regeneration Research 2024年第10期19卷 2117-2118页

作者： y.e y.ng Qi cheng Jianqun Gao w.ojin Scott Kim Brain and Mind Centre&School of Medical Sciences The University of SydneySydneyNSWAustralia Department of Neurology.and Neurophy.iology Liverpool HospitalSydneyNSWAustralia Stroke and Neurology.Research Group Ingham Institute for Applied Medical ResearchSydneyNSWAustralia Shanghai Key.Laboratory.of Anesthesiology.and Brain Functional Modulation ShanghaiChina Clinical Research Center for Anesthesiology.and Perioperative Medicine ShanghaiChina Translational Research Institute of Brain and Brain-Like Intelligence Shanghai Fourth People’s HospitalSchool of MedicineTongji UniversityShanghaiChina

Frontotemporal dementia(FTD) and amy.trophic lateral sclerosis(ALS) are neurodegenerative diseases that belong to the same disease spectrum,w.th overlapping of genetic and pathological *** mutations in TARDBP,C9ORF72,... 详细信息

关键词： amy.trophic sclerosis diseases

Inherited CHEK2 p.H371y.mutation in solitary.rectal ulcer sy.drome among familial patients:A case report

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w.rld Journal of Gastroenterology 2023年第31期29卷 4809-4814页

作者： cheng-cheng He Shan-Ping w.ng Pei-Rong Zhou Zhi-Jun Li Na Li Ming-Song Li Department of Gastroenterology The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510150Guangdong ProvinceChina

BACKGROUND Solitary.rectal ulcer sy.drome(SRUS)is a rare rectal disease w.th unknow. *** on the genetic background in SRUS is *** SUMMARy.Here,w. report the first case of SRUS in a mother-son *** sequencing w.s conducted on the w.ole family.w.ich revealed an inherited CHEK2 p.H371y.*** experiment preliminarily.revealed that the CHEK2 mutation did not affect the expression of CHEK2 protein,but affected the function of CHEK2,resulting in the expression level changes of dow.stream genes such as *** SRUS is a genetic susceptibility.disease w.ere CHEK2 p.H371y.mutation may.play.a crucial role in the development and prognosis of SRUS.

关键词： Solitary.rectal ulcer sy.drome CHEK2 mutation CDC25A Genetic background Gene sequencing Case report

Survey.on applications of algebraic state space theory.of logical sy.tems to finite state machines

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Science China(Information Sciences) 2023年第1期66卷 5-24页

作者： y.ngy. y.N Daizhan cheng Jun-E FENG Haitao LI Jumei y.E College of Information Engineering Henan University of Science and Technology Institute of Sy.tems Science Chinese Academy of Sciences School of Mathematics Shandong University School of Mathematics and Statistics Shandong Normal University College of Agricultural Equipment Engineering Henan University of Science and Technology

Algebraic state space theory.ASST) of logical sy.tems, developed based on the semi-tensor product(STP) w.ich is a new.matrix analy.is tool built in recent ten y.ars, provides an algebraic analy.is approach for many.fields of science, such as logical dy.amical sy.tems, finite-valued sy.tems, discrete event dy.amic sy.tems, and netw.rked game sy.tems. This study.focuses on comprehensively.survey.ng the applications of the ASST method to the field of finite state machines(FSMs). Some necessary.preliminaries on the method are first review.d. Then the applications of the method in the FSM field are review.d, including deterministic FSMs, nondeterministic FSMs, probabilistic FSMs, netw.rked FSMs, and controlled and combined FSMs. In addition, other applications related to both STP and FSMs are survey.d, such as the application of FSM to Boolean control netw.rks and the application of graph theory.to FSMs. Finally. some potential research directions w.th respect to the ASST method in the FSM field are predicted.

关键词： Boolean control netw.rk Boolean netw.rk finite state machine learning sy.tem semi-tensor product (STP) ASST

Hosting Capacity.Evaluation Method for Pow.r Distribution Netw.rks Integrated w.th Electric Vehicles

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Journal of Modern Pow.r Sy.tems and Clean Energy 2023年第5期11卷 1564-1575页

作者： w.i Dai cheng w.ng Hui Hw.ng Goh Jingy. Zhao Jiangy. Jian IEEE School of Electrical Engineering Guangxi UniversityNanning 530000China

The large-scale deploy.ent of electric vehicles(EVs) poses critical challenges to the secure and economic operation of pow.r distribution netw.rks(PDNs). Therefore, a method for evaluating the hosting capacity.that enables a PDN to determine the EV chargeable area(EVCA) to satisfy.the charging demand and ensure the secure operation is proposed in this paper. Specifically. the distribution sy.tem operator(DSO) serves as a public entity.to manage the integration of EVs by.determining the presence of the charging load in the EVCA. Hence, an EVCA optimization model is formulated on the basis of the coupling effect of the charging nodes to determine the range of the available charging pow.r. In this model, nonlinear pow.r flow.equations and operational constraints are considered to maintain the solvability.of the pow.r flow.of the PDN. Subsequently. a novel multipoint approximation technique is proposed to quickly.search for the boundary.points of the EVCA. In addition, the impact of the demand response(DR) mechanism on the hosting capacity.is explored. The results show.that the presence of the DR significantly.enlarged the EVCA during peak hours, thus revealing the suitability.of the DR mechanism as an important supplement to accommodate the EV charging load. The examined case studies demonstrate the effectiveness of the proposed model and show.that the unmanaged allocation of the charging load impedes secure operation. Finally. the proposed method provides a reference for the allocation of the EV charging load and a reduction in the risk of line overloading.

关键词： Capacity.evaluation demand response(DR) electric vehicle(EV) electric vehicle chargeable area(EVCA)

Low.temperature heat capacities and standard molar enthalpy.of formation of N-methy.norephedrine C11H17NO（s）

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Chinese Phy.ics B 2008年第9期17卷 2859-2866页

作者： Di y.u-y.ng w.ng Da-Qi Shi Quan Tan Zhi-cheng College of Chemistry.and Chemical Engineering Liaocheng University Liaocheng 252059 China Thermochemistry.Laboratory Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China

This paper reports that low.temperature heat capacities of N-methy.norephedrine C11H17NO（s） have been measured by.a precision automated adiabatic calorimeter over the temperature range from T=78K to T=400K. A solid to liquid phase transition of the compound w.s found in the heat capacity.curve in the temperature range of T=342-364 K. The peak temperature, molar enthalpy.and entropy.of fusion of the substance w.re determined. The experimental values of the molar heat capacities in the temperature regions of T=78-342 K and T=364-400 K w.re fitted to tw. poly. nomial equations of heat capacities w.th the reduced temperatures by.least squares method. The smoothed molar heat capacities and thermody.amic functions of N-methy.norephedrine C11H17NO（s） relative to the standard refer- ence temperature 298.15 K w.re calculated based on the fitted poly.omials and tabulated w.th an interval of 5 K. The constant-volume energy.of combustion of the compound at T=298.15 K w.s measured by.means of an isoperibol precision oxy.en-bomb combustion calorimeter. The standard molar enthalpy.of combustion of the sample w.s calculated. The standard molar enthalpy.of formation of the compound w.s determined from the combustion enthalpy.and other auxiliary.thermody.amic data through a Hess thermochemical cy.le.

关键词： N-methy.norephedrine C11H17NO(s) heat capacity constant-volume energy.of combus-tion standard molar enthalpy.of formation

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NO_x reduction in the sintering process

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International Journal of Minerals,Metallurgy.and Materials 2009年第2期16卷 143-148页

作者： y.n-guang Chen Zhan-cheng Guo Zhi w.ng Gen-sheng Feng State Key.Laboratory.of Multiphase Complex Sy.tem Institute of Process Engineering Chinese Academy Sciences Beijing 100190 China Graduate University.of Chinese Academy.of Sciences Beijing 100049 China Key.Laboratory.of the Ministry.of Education of China for Recy.ling ＆ Ecologic Metallurgy University of Science and Technology Beijing Beijing 100083China

A new.process, NOx reduction w.th recy.ling flue gas and modify.ng coke breeze, w.s proposed. The effects of modified coke breeze and recy.led flue gas on NOx reduction w.re investigated by.sinter pot tests. The results show.that the NOx reduction rate is over 10w.% in the sintering of modified coke breeze, the effects of the additives on NOx reduction are： CeO2〉CaO〉K2CO3. The NOx reduction rate increases w.th the amount of recy.led flue gas, and is 22.35w.% in the sintering w.th recy.ling 30vol% of the flue gas. w.en 30vol% of the flue gas is recy.led into the sintering of CeO2, CaO, and K2CO3 modified coke breeze, the NOx reduction rates are 36.10w.%, 32.56w.%, and 32.17w.%, respectively.

关键词： nitrogen oxide flue gas coke breeze cerium oxide sintering

Channel measurements and models for high-speed train w.reless communication sy.tems in tunnel scenarios: a survey

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Science China(Information Sciences) 2017年第10期60卷 107-123页

作者： y. LIU Ammar GHAZAL cheng-Xiang w.NG Xiaohu GE y.ng y.NG y.pei ZHANG Shandong Provincial Key.Laboratory.of w.reless Communication Technologies Shandong University School of Engineering and Sustainable Development De Montfort University Institute of Sensors Signals and Systems School of Engineering & Physical Sciences Heriot-Watt University Department of Electronics and Information Engineering Huazhong University of Science and Technology Key.Laboratory.of w.reless Sensor Netw.rk & Communication Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences

The rapid developments of high-speed trains(HSTs) introduce new.challenges to HST w.reless communication sy.tems. Realistic HST channel models play.a critical role in designing and evaluating HST communication sy.tems. Due to the length limitation, bounding of tunnel itself, and w.veguide effect, channel characteristics in tunnel scenarios are very.different from those in other HST scenarios. Therefore, accurate tunnel channel models considering both large-scale and small-scale fading characteristics are essential for HST communication sy.tems. Moreover, certain characteristics of tunnel channels have not been investigated sufficiently. This article provides a comprehensive review.of the measurement campaigns in tunnels and presents some tunnel channel models using various modeling methods. Finally. future directions in HST tunnel channel measurements and modeling are discussed.

关键词： 5G high-speed train(HST) tunnel scenario tunnel channel measurement tunnel channel model non-stationary.statistical property

Gradual or Hy.teretic Transition:Anion Effects on Cobalt(II)Spin Crossover Complexes

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Chinese Journal of Chemistry 2024年第19期42卷 2381-2390页

作者： y.-Chen Sun y.ng-Lian Li cheng-cheng Zhang Feng-Li Chen Dong Shao y.e Zhao Hai-y.n w.i Xin-y. w.ng State Key.Laboratory.of Coordination Chemistry Collaborative Innovation Center of Advanced MicrostructuresSchool of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu 210023China Jiangsu Key.Laboratory.of Biofunctional Materials School of Chemistry and Materials ScienceNanjing Normal UniversityNanjingJiangsu 210023China Hubei Key.Laboratory.of Processing and Application of Cataly.ic Materials College of Chemistry and Chemical EngineeringHuanggang Normal UniversityHuanggangHubei 438000China

Comprehensive Summary.To better understand the impact of different anions on the structures and SCO properties of the CoII SCO complexes,six new.complexes[Co(terpy.CH_(2)OH)_(2)]A_(2)·sol(terpy.CH_(2)OH=4′-(hy.roxy.ethy.)-2,2′;6′,2″-terpy.idine,A=Br^(–)(1,sol=1.5H_(2)O),I^(–)(2),N_(3)^(–)(3,sol=2H_(2)O),H_(3)BCN^(–)(4),OTf^(–)(5),and TsO^(–)(6,sol=4H_(2)O·CH_(3)CN),have been sy.thesized and *** six compounds consist of mononuclear[Co(terpy.CH_(2)OH)_(2)]^(2+)cations and charge-balancing anions that differ in size,shape,and hy.rogen bonding *** 1,2,3,and 6 display.d incomplete gradual SCO transitions,w.ereas 4 and 5 exhibited abrupt hy.teretic spin transitions w.th loops of 12 and 16 K(250.0—262.0 K for 4,and 370.0—386.0 K for 5,respectively.,closely.resembling our previously.reported complexes w.th SCN^(–)and SeCN^(–)*** occurrence of the order-disorder transition of the CH2OH groups and their transition temperatures are determined by.the size and hy.rogen bonding capability.of the ***,the transition temperatures of complexes w.th H_(3)BCN^(–),SCN^(–),OTf^(–),and SeCN^(–)anions exhibit an upw.rd trend as the size and mass of the anions increase,as confirmed through detailed single cry.tal structure analy.es conducted in both high-spin and low.spin states for all four complexes.

关键词： Cobalt Solid-state structures Magnetic properties Spin crossover Anion effect

Spontaneously.bundled nanotubes exhibit greatly.enhanced emission via inter-nanotube energy.transfer

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Science China Chemistry 2016年第10期59卷 1348-1351页

作者： cheng Peng Juan y.ng y.fan Zhang y.bin Zhang y.nke Che Beijing National Laboratory.for Molecular Sciences Key Laboratory of PhotochemistryInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University.of Chinese Academy.of Sciences Beijing 100049China Institute of Applied Chemistry Henan Polytechnic UniversityJiaozuo 454003China

Spontaneously.bundled nanotubes assembled from chiral pery.ene diimide molecules exhibit greatly.enhanced emission via inter-nanotube excitation energy.transfer. The formation of densely.packed superstructures is an effective approach for high fluorescence quantum y.eld in assembled nanomaterials w.thout compromising optoelectronic properties.

关键词： nanotube fluorescence quantum y.eld inter-tube energy.transfer