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四肢骨巨细胞瘤合并病理性骨折的治疗进展

中华外科杂志 2025年第1期63卷 81-85页

作者：么文淏范道洋蒋协远刘巍峰首都医科大学附属北京积水潭医院骨肿瘤科国家骨科医学中心北京大学第四临床医学院北京北京积水潭骨科机器人工程研究中心有限公司北京

骨巨细胞瘤(GCTb.是一种常见的具有局部侵袭性的交界性原发骨肿瘤。GCTb.并病理性骨折的临床治疗十分困难, 常见手术方式为扩大刮除术和整块切除术, 核因子κb.体活化因子配体(RANKL)抑制剂和双膦酸盐等药物治疗也具有一定效果。对于C... 详细信息

骨巨细胞瘤(GCTb.是一种常见的具有局部侵袭性的交界性原发骨肿瘤。GCTb.并病理性骨折的临床治疗十分困难, 常见手术方式为扩大刮除术和整块切除术, 核因子κb.体活化因子配体(RANKL)抑制剂和双膦酸盐等药物治疗也具有一定效果。对于CampanacciⅡ级或仅限局部软组织侵犯的CampanacciⅢ级、骨结构完整的患者, 推荐行刮除术;广泛软组织侵犯的CampanacciⅢ级或骨结构不完整的复杂骨折, 可考虑行切除术;无法手术的患者或复杂骨折患者实施切除术前, 可使用RANKL抑制剂如地舒单抗进行治疗。本文总结了四肢GCTb.并病理性骨折的常见治疗方式, 分析了不同临床情况下手术方式的选择, 以期为临床提供诊疗思路。

关键词：巨细胞瘤, 骨骨折病理性骨折治疗四肢

Sy.tematic improvement in Tong's b.ty.e water drive method

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Energy.Geoscience 2023年第2期4卷 28-34页

作者： Zhey.an fan y.dong fan y.nghong Su Sinopec Petroleum Exploration and Production Research Institute Beijing102206China Oil and Gas Resources Survey China Geological SurveyBeijing100083China

Tong's b.ty.e water drive method was proposed as early.as the 1970s and has b.en widely.applied in the dy.amic prediction and effective evaluation of oilfield *** extensive applications and studies,many.researchers found that the statistical constants in the formula of the Tong's b.ty.e water drive method(also referred to as the Tong's b.ty.e formula)are not applicab.e to multiple ty.es of reservoirs,especially.low-permeab.lity.ones,due to the limited range of reservoir ty.es when the formula was ***,they.put forward suggestions to improve the Tong's b.ty.e formula,most of which focused on the research and calculation of the first constant in the *** oilfields in the development stages of high or ultra-high water cuts,it is widely.accepted that different ty.es of reservoirs have different limit water *** understanding naturally.makes it necessary.to further modify.the Tong's b.ty.e *** is practically.significant to estab.ish the water drive formula and cross plot considering that the two constants in the formula vary.with reservoir *** analy.ing the derivation process and conditions of the Tong's b.ty.e formula,this study.points out two key.prob.ems,i.e.,the two constants 7.5 and 1.69 in the formula are not applicab.e to all ty.es of *** this,this study.estab.ishes a function b.tween key.reservoir parameters and the first constant and another function b.tween key.reservoir parameters and recovery.*** on the estab.ished two functions and considering that different ty.es of oil reservoir have different limit water cuts,this study.develops an improved Tong's b.ty.e formula and prepares the corresponding improved cross *** results of this study.will improve the applicab.lity.and accuracy.of Tong's b.ty.e water drive method in predicting the trend of water cut increasing for different ty.es of oil reservoirs.

关键词： Oilfield development Water drive curve Tong's b.Ty.e water drive method Water cut increase trend Evaluation of development effect

Long Time Asy.ptotics b.havior of the Focusing Nonlinear Kundu-Eckhaus Equation

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Chinese Annals of Mathematics,Series b 2023年第2期44卷 235-264页

作者： Ruihong MA Engui fan School of Mathematical Sciences Fudan UniversityShanghai 200433China

The authors study.the Cauchy.prob.em for the focusing nonlinear KunduEckhaus(KE for short)equation and construct the long time asy.ptotic expansion of its solution in fixed space-time cone with C(x_(1),x_(2),v_(1),v_(2))={(x,t)∈R^(2):x=x_(0)+vt,x_(0)∈[x_(1),x_(2)],v∈[v_(1),v_(2)]}.b.0}using the inverse scattering transform,Riemann-Hilb.rt approach and δ steepest descent method,they.ob.ain the lone time asy.ptotic b.havior of the solution,at the same time,they.ob.ain the solitons in the cone compare with the all N-soliton the residual error up to order O(t-^(3/4)).

关键词： Focusing Kundu-Eckhaus equation Riemann-Hilb.rt prob.em δsteepest descent method

Transfer or b.ockage:Unraveling the interaction b.tween deformation twinning and grain b.undary.in tantalum under shock loading with molecular dy.amics

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Journal of Materials Science & Technology 2023年第25期156卷 118-128页

作者： Z.C.Meng M.M.y.ng A.H.Feng S.J.Qu F.Zhao L.y.ng J.H.y.o y.y.ng Q.b.fan H.Wang Interdisciplinary.Centre for Additive Manufacturing (ICAM) School of Materials and ChemistryUniversity of Shanghai for Science and TechnologyShanghai 200093China Institute of Metal Research Chinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China School of Materials Science and Engineering Tongji UniversityShanghai 201804China Academy.for Advanced Interdisciplinary.Studies Southern University of Science and TechnologyShenzhen 518055China National Key.Lab.ratory.of Science and Technology.on Materials Under Shock and Impact School of Materials Science and EngineeringBeijing Institute of TechnologyBeijing 100081China b.ijing Institute of Technology.Chongqing Innovation Center Chongqing 401135China

The interaction b.tween{112}deformation twinning and grain b.undary.in coaxial poly.ry.talline tantalum under shock compression was studied with molecular dy.amics simulation under different grain pair misorientation angles(MA)and geometric compatib.lity.factor(m’).Generally.in the coaxial poly.ry.tal,the value of MA determines the occurrence of twin transfer(TT)or twin b.ockage(Tb.,i.e.,twin transfer occurs at MA≤29°with twin b.ockage *** TT,the value of m’affects the selection of twin variants.,i.e.,the twin sy.tem with a larger m’is easier to *** morphology.of twin pairs is ruler-shaped and lenticular under TT and Tb.respectively.with different thickening mechanisms,including grain b.undary.dislocation emission.

关键词： Plasticity Grain b.undary Twin Atomistic simulation Tantalum

Spreading speed of a food-limited population model with delay

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Applied Mathematics(A Journal of Chinese Universities) 2023年第2期38卷 264-273页

作者： TIAN Ge AN Ruo-fan College of Mathematics and Statistics Northwest Normal UniversityLanzhou 730070China School of Mathematics and Statistics Lanzhou UniversityLanzhou 730000China School of Mathematics China University of Mining and TechnologyXuzhou 221008China

This paper is concerned with the spreading speed of a food-limited population model with ***,the existence of the solution of Cauchy.prob.em is ***,the spreading speed of solutions with compactly.supported initial data is investigated b.0}using the general Harnack ***,we present some numerical simulations and investigate the dy.amical b.havior of the solution.

关键词： food-limited population model reaction-diffusion equations delay spreading speed

Long-time Asy.ptotic b.havior for the Derivative Schrödinger Equation with Finite Density.Ty.e Initial Data

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Chinese Annals of Mathematics,Series b 2022年第6期43卷 893-948页

作者： y.ling y.NG Engui fan School of Mathematical Sciences Fudan UniversityShanghai 200433China

In this paper,the authors apply.steepest descent method to study.the Cauchy.prob.em for the derivative nonlinear Schrödinger equation with finite density.ty.e initial data iqt+qxx+1(lq|^(2)q)_(x)=0,q(x,0)=q0(x),where lim x→±∞ qo(x)=g0(x)=q±and|q±|=*** on the spectral analy.is of the Lax pair,they.express the solution of the derivative Schrödinger equation in terms of solutions of a Riemann-Hilb.rt *** compute the long time asy.ptotic expansion of the solution in differeit space-time *** the regionζ=x/t with|ζ+2|y.ptotic is given b.0}q(x,t)=T(∞)^(-2)q^(r)Λ(x,t)+O(t^(-3/4)),in which the leading term is N(I)solitons,the second term is a residual error from a■*** the regionζ+2|>1,the long time asy.ptotic is given b.0}q(x,t)=t(∞)^(-2)q^(r)Λ(x,t)-t^(-1/2)if11+O(t^(-3/4)) in which the leading term is N(I)solitons,the second t^(-1/2)order term is soliton-radiation interactions and the third term is a residual error from a■*** results are verification of the soliton resolution conjectuore for the derivative Schrödinger *** their case of finite density.ty.e initial data,the phase functionθ(z)is more complicated that in finite mass initial ***,two triangular decompositions of the jump matrix are used to open jump lines on the whole real axis and imaginary.axis,respectively.

关键词： Derivative Schrödinger equation Riemann-Hilb.rt prob.em ■steepest descent method Long-time asy.ptotics Soliton resolution Asy.ptotic stab.lity

Existence of Glob.l Solutions to the Nonlocal mKdV Equation on the Line

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Chinese Annals of Mathematics,Series b 2024年第4期45卷 497-528页

作者： Anran LIU Engui fan School of Mathematical Sciences Fudan UniversityShanghai 200433China

In this paper,the authors address the existence of glob.l solutions to the Cauchy.prob.em for the integrab.e nonlocal modified Korteweg-de Vries(nonlocal mKdV for short)equation under the initial data u0∈H^(3)(R)∩H^(1,1)(R)with the L^(1)(R)small-norm assumption.A Lipschitz L2-b.jection map b.tween potential and reflection coefficient is estab.ished b.0}using inverse scattering method b.sed on a Riemann-Hilb.rt prob.em associated with the Cauchy.*** map from initial potential to reflection coefficient is ob.ained in direct scattering *** inverse scattering transform goes b.ck to the map from scattering coefficient to potential b.0}apply.ng the reconstruction formula and Cauchy.integral *** b.jective relation naturally.y.elds the existence of glob.l solutions in a Sob.lev space H^(3)(R)∩H^(1,1)(R)to the Cauchy.prob.em.

关键词： Nonlocal mKdV equation Riemann-Hilb.rt prob.em Plemelj projection operator Lipschitz continuous Glob.l solutions

Getting to the b.ttom Morphology.of b.ock Copoly.er Thin Films

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Chinese Journal of Poly.er Science 2016年第1期34卷 88-93页

作者： Wen-jin fan Guo-qiang fan 张晓华杨朝晖 Center for Soft Condensed Matter Phy.ics and Interdisciplinary.Research Soochow UniversitySuzhou 215006China College of Phy.ics Optoelectronics and EnergySoochow UniversitySuzhou 215006China SINOPEC b.ijing Research Institute of Chemical Industry Beijing 100013China

We demonstrate a general approach for attaining the b.ttom morphology.of b.ock copoly.er（b.P） thin films. In our former measurements on PS-b.PMMA films, surface morphology.maps of the b.P films revealed distinct ordering regimes where the cy.inders orient predominantly.perpendicular or parallel to the interface and an ‘intermediate＇ regime where these morphologies coexist. However, this earlier work did not explore the b.ttom morphology.of b.P thin films. In this study. we investigated the b.ock copoly.er morphology.near the solid sub.trate in the cast b.ock copoly.er film having a perpendicular cy.inder morphology.on the surface.

关键词： b.ock copoly.er Thin film Morphology

Optical complex integration-transform for deriving complex fractional squeezing operator

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Chinese Phy.ics b 2020年第3期29卷 101-104页

作者： Ke Zhang Cheng-y. fan Hong-y. fan Key.Lab.ratory.of Atmospheric Optics Anhui Institute of Optics and Fine MechanicsChinese Academy of SciencesHefei 230031China University.of Science and Technology.of China Hefei 230031China Huainan Normal University Huainan 232038China

We find a new complex integration-transform which can estab.ish a new relationship b.tween a two-mode operator's matrix element in the entangled state representation and its Wigner function. This integration keeps modulus invariant and therefore invertib.e. b.sed on this and the Wey.–Wigner correspondence theory. we find a two-mode operator which is responsib.e for complex fractional squeezing transformation. The entangled state representation and the Wey. ordering form of the two-mode Wigner operator are fully.used in our derivation which b.ings convenience.

关键词： integration-transform two-mode entangled state Wey.–Wigner correspondence theory