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Metal-organic framework coated titanium dioxide nanorod array.p-n heterojunction photoanode for solar water-splitting

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Nano Research 2019年第3期12卷 643-650页

作者： Hui y.ng Joeseph Bright Sujan Kasani Peng Zheng Terence Musho Banglin chen Ling Huang Nianqiang Wu Department of Mechanical and Aerospace Engineering West Virginia University Morgantown WV 26506-6106 USA C. eugene Bennett Department of Chemistry West Virginia University Morgantown WV 26506-6045 USA Department of Pharmaceutical Science West Virginia University Morgantown WV 26506-9530 USA Lane Department of Computer Science and Electrical Engineering West Virginia University Morgantown WV 26506 USA Department of Chemistry University of Texas at San Antonio One UTSA Circle San Antonio TX 78249-1604 USA Institute of Advanced Materials (IAM) Nanjing Tech University (NanjingTech) 30 South Puzhu Road Nanjing 211816 China

This paper presents a p-n heterojunction photoanode based on a p-ty.e porphy.in metal-organic framework (MOF) thin film and an n-ty.e rutile titanium dioxide nanorod array.for photoelectrochemical water splitting. The TiO2@MOF core-shell n anorod array.is formed by.coati ng an 8 nm thick MOF lay.r on a vertically.aligned TiO2 nanorod array.scaffold via a lay.r-by.lay.r self-assembly.method. This vertically.aligned core-shell nanorod array.enables a long optical path length but a short path length for extraction of photogenerated minority.charge carriers (holes) from TiO2 to the electroly.e. A p-n junction is formed between TiO2 and MOF, which improves the extraction of photogenerated electr ons and holes out of the TiO2 nano rods. In additi on, the MOF coati ng sign ificantly.improves the efficie ncy.of charge in jecti on at the photoanode/electroly.e interface. Introduction of Co(lll) into the MOF lay.r further enhances the charge extraction in the photoanode and improves the charge injection efficiency. As a result, the photoelectrochemical cell with the TiO2@Co-MOF nanorod array.photoanode exhibits a photocurrent density.of 2.93 mA/cm^2 at 1.23 V (vs. RHE), which is ~ 2.7 times the photocurrent achieved with bare T1O2 nanorod array.under irradiation of an unfiltered 300 W Xe lamp with an output power density.of 100 mW/cm^2.

关键词： metal-organic framework water-splitting p-n junction photoanode titanium dioxide

缺失PUF家族基因的卵母细胞可以成熟和受精

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南京医科大学学报（自然科学版） 2016年第7期36卷 774-777页

作者：陈霞朱梦怡苏友强徐宇君南京医科大学生殖医学国家重点实验室江苏南京211166

目的 :研究PUF家族基因[Pumilio1(Pum1)和Pumilio2(Pum2)]在雌性生育能力和生殖细胞减数分裂过程中的作用。方法:在Pum1基因位置携带lox P位点的Pum2基因全敲鼠的基础上,利用生殖细胞特异性表达的Cre-Vasa-Cre介导Pum1基因条件性敲除,... 详细信息

目的 :研究PUF家族基因[Pumilio1(Pum1)和Pumilio2(Pum2)]在雌性生育能力和生殖细胞减数分裂过程中的作用。方法:在Pum1基因位置携带lox P位点的Pum2基因全敲鼠的基础上,利用生殖细胞特异性表达的Cre-Vasa-Cre介导Pum1基因条件性敲除,以此获得Pum基因双敲小鼠模型Vasa-cre:Pum1F/FPum2-/-(VDKO)。同时,对Pum基因双敲小鼠进行生殖表型分析。结果:1交配实验结果表明,雌性VDKO小鼠的生育能力显著下降,但仍可以产生后代;2VDKO小鼠卵母细胞体外成熟过程不受影响。结论:Pum蛋白不影响小鼠卵子发生发育过程。

关键词： Pum VDKO 卵母细胞育性

Matrix metalloproteinase-9 in the initial injury.after hepatectomy.in mice

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World Journal of Gastroenterology 2013年第20期19卷 3027-3042页

作者： Norifumi Ohashi Tomohide Hori Florence chen Sura Jermanus Akimasa Nakao Shinji Uemoto Justin H Nguy.n Gastroenterological Surgery Nagoya University Graduate School of MedicineNagoyaAichi 466-8550Japan Divisions of Hepato-PancreatoBiliary Transplant and Pediatric SurgeryDepartment of SurgeryKyoto University Graduate School of MedicineKyoto 606-8507Japan Department of Neuroscience Mayo ClinicJacksonvilleFL 32224United States Division of Transplant Surgery Department of TransplantationMayo Clinic in FloridaJacksonvilleFL 32224United States

AIM:To investigate the role of matrix metalloproteinase(MMP)-9 in the pathogenesis of postoperative liver failure(PLF) after extended hepatectomy.EH).METHODS:An insufficient volume of the remnant liver(RL) results in higher morbidity.and mortality.and a murine model with 80%-hepatectomy.was *** investigations were performed 6 h after *** were first divided into two groups based on the postoperative course(i.e.,the PLF caused or did not),and MMP-9 expression was measured by.Western *** source of MMP-9 was then determined by.immunohistological *** inhibitor of metalloproteinase(TIMP)-1 is the endogenous inhibitor of MMP-9,and MMP-9 behavior was assessed by.the experiments in wild-ty.e,MMP-9(-/-) and TIMP-1(-/-) mice by.Western blotting and gelatin *** behavior of neutrophils was also assessed by.immunohistological *** anti-MMP-9 monoclonal antibody.and a broadspectrum MMP inhibitor were used to examine the role of ***:Sy.ptomatic mice showed more severe PLF(histopathological assessments:2.97 ± 0.92 vs 0.11 ± 0.08,P y.es appeared to be the main source of MMP-9,because MMP-9 expression corresponding with CD11b positive-cell was observed in the findings of immunohistological *** the histopathological findings,the PLF was improved in MMP-9(-/-) mice(1.65% ± 0.23% vs 0.65% ± 0.19%,P y.disturbed in MMP-9-blocked mice in the histopathological assessments(9.6 ± 1.9 vs 4.2 ± 1.2,P y.is associated with MMP-9 derived from neutrophil

关键词： Matrix metalloproteinase Shear stress Sinusoidal injury Hepatectomy Portal hy.ertension

A Discussion on the Translation of Popular Science Articles on Nuclear Fusion from the Perspective of Functional Equivalence

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校园英语 2019年第39期 243-244页

作者： chen LIN Southwestern Institute of Phy.ics

eugene Nida’s Functional Equivalence focuses on target readers, stressing fluency.and naturalness of translation. This provides a practical guidance to translation strategies and translation criticism. Excellent popular science articles on nuclear fusion, represented by.the ones on ITER(International Thermonuclear Experimental Reactor) website, feature vivid and common language. This article will make a brief analy.is of the translation of these articles from the perspective of Functional Equivalence.

关键词： Functional Equivalence nuclear fusion popular science articles

论《国王正在死去》对“死亡恐惧”的双重伦理规训

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外国文学研究 2016年第6期38卷 79-87页

作者：陈溪武汉大学文学院

本文于荒诞派戏剧的传统解读模式和经典阐释路径之外,关注尤奈斯库戏剧《国王正在死去》中的"死亡恐惧"和与之相关的"伦理规训"过程,并结合作家自身的创作理念与相关思考,力图对这一荒诞派经典作品提出新的观照视角和作出新的文本解读... 详细信息

本文于荒诞派戏剧的传统解读模式和经典阐释路径之外,关注尤奈斯库戏剧《国王正在死去》中的"死亡恐惧"和与之相关的"伦理规训"过程,并结合作家自身的创作理念与相关思考,力图对这一荒诞派经典作品提出新的观照视角和作出新的文本解读。尤奈斯库用艺术想象在该剧中安排了一场处于伦理价值和日常人性的冲突境遇中的"死亡演练",使得对"死亡恐惧"的伦理规训过程成为中心问题,并于存在意义之上显现出双重性与悖论性。一方面,伦理规训需要以"征服"和"战胜"的方式来避免"死亡恐惧"对存在意义和价值的吞噬;另一方面,伦理规训又必须以留存"死亡恐惧"为前提来确保在存在中直面、对抗和思考死亡的必然性。然而在这一双重伦理规训行动的绝对胜利之下,是回归绝对主体性的自闭与缺失,以及对于在他者之域中重建价值可能性的忽略与盲视。

关键词：尤奈斯库《国王正在死去》 “死亡恐惧” “伦理规训” 双重性

Targeting cancer stem cell pathway. for cancer therapy

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Signal Transduction and Targeted Therapy 2020年第1期5卷 2395-2429页

作者： Liqun y.ng Pengfei Shi Gaichao Zhao Jie Xu Wen Peng Jiay. Zhang Guanghui Zhang Xiaowen Wang Zhen Dong Fei chen Hongjuan Cui State Key.Laboratory.of Silkworm Genome Biology Southwest University400716 ChongqingChina Cancer Center Medical Research InstituteSouthwest University400716 ChongqingChina Department of Pharmaceutical Sciences Eugene Applebaum College of Pharmacy and Health SciencesWayne State UniversityDetroitMI 48201USA

Since cancer stem cells(CSCs)were first identified in leukemia in 1994,they.have been considered promising therapeutic targets for cancer *** cells have self-renewal capacity.and differentiation potential and contribute to multiple tumor malignancies,such as recurrence,metastasis,heterogeneity.multidrug resistance,and radiation *** biological activities of CSCs are regulated by.several pluripotent transcription factors,such as OCT4,Sox2,Nanog,KLF4,and *** addition,many.intracellular signaling pathway.,such as Wnt,NF-κB(nuclear factor-κB),Notch,Hedgehog,JAK-STAT(Janus kinase/signal transducers and activators of transcription),PI3K/AKT/mTOR(phosphoinositide 3-kinase/AKT/mammalian target of rapamy.in),TGF(transforming growth factor)/SMAD,and PPAR(peroxisome proliferator-activated receptor),as well as extracellular factors,such as vascular niches,hy.oxia,tumor-associated macrophages,cancer-associated fibroblasts,cancer-associated mesenchy.al stem cells,extracellular matrix,and exosomes,have been shown to be very.important regulators of ***,vaccines,antibodies,and CAR-T(chimeric antigen receptor T cell)cells have been developed to specifically.target CSCs,and some of these factors are already.undergoing clinical *** review summarizes the characterization and identification of CSCs,depicts major factors and pathway. that regulate CSC development,and discusses potential targeted therapy.for CSCs.

关键词： cancer stem pathway.

Coronavirus disease(COVID-19):The need to maintain regular phy.ical activity.while taking precautions

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Journal of Sport and Health Science 2020年第2期9卷 103-104页

作者： Peijie chen Lijuan Mao George P.Nassis Peter Harmer Barbara E.Ainsworth Fuzhong Li Shanghai University.of Sport Shanghai 200438China Shanghai Municipal Education Commission Shanghai 200003China Department of Sports Science and Clinical Biomechanics University of Southern DenmarkOdense 5230Denmark Department of Exercise and Health Science Willamette UniversitySalemOR 97301USA School of Nutrition and Health Promotion Arizona State UniversityPhoenixAZ 85004USA Oregon Research Institute EugeneOR 97403USA

The on-going Coronavirus disease(COVID-19)outbreak in China has become the world's leading health headline and is causing major panic and public *** January.30,2020,the World Health Organization(WHO)declared that the new coronavirus outbreak is a public health emergency.of international concern.1 The virus has already.had a direct impact on more than 10 million people in the city.of Wuhan and has reached other parts of China as well,posing a health threat of unknown magnitude *** of February.8,2020,WHO reported 34,886 confirmed cases of COVID-19 globally.with 34,589 of them occurring in China(including 6101 severe cases and 723 deaths).A total of 288 other confirmed cases(with 1 death)have been reported in 24 countries,including Japan,Australia,Germany.and United States.2 However,these daily.estimates are expected to rise even higher as reports from health authorities in China3 are gathered and near real-time updates of the Johns Hopkins virus dashboard are made 4 The outbreak has caused governments in various countries to take swift and protective *** China,these included putting cities on lockdown,5 implementing travel wamings/bans and cancellations,6 extending national holiday.,and closing schools and postponing classes7.

关键词： globally maintain travel

Returning Chinese school-aged children and adolescents to phy.ical activity.in the wake of COVID-19: Actions and precautions

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Journal of Sport and Health Science 2020年第4期9卷 322-324页

The Coronavirus disease-2019(COVID-19)pandemic is still spreading *** of April 7,2020,it has reached 184 countries and territories,infecting more than 1.4 million people worldwide with more than 82,000 deaths.1 The situation in China has improved significantly.since December 31,2019.2 Owing to the unprecedented and effective quarantine measures taken across the country.Chinese health authorities reported on March 18,2020,that for the first time since the outbreak no new locally.transmitted COVID-19 cases had been reported,marking a major turning point in the fight against the highly.contagious coronavirus.3 Since then,the daily.number of new cases in the mainland of China has dropped to double digits,with new infections primarily.originating from incoming air passengers from outside China.

关键词： mainland outside turning

Profiling of histone H3 trimethy.ation and distinct epigenetic pattern of chromosome y.in the transformed bronchial epithelial cells induced by.consecutive arsenic treatment

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Genes & Diseases 2022年第5期9卷 1160-1162页

作者： y.ran Qiu Zhuoy.e Bi y.o Fu Lingzhi Li Priy. Wadgaonkar Bandar Almutairy.Wenxuan Zhang Chitra Thakur Fei chen Stony.Brook Cancer Center Renaissance School of MedicineThe State University of New YorkStony Brook UniversityLauterbur DriveStony BrookNY 11794USA Department of Pharmaceutical Sciences Eugene Applebaum College of Pharmacy and Health SciencesWayne State UniversityDetroitMI 48201USA c Department of PathologyRenaissance School of MedicineStony Brook UniversityStony BrookNY 11794USA

To the Editor:Environmental arsenic is a known human carcinogen that is associated with cancers in lung,liver,skin,breast,bladder,kidney.prostate,etc.1 However,the underpinnings of ma-lignant transformation of the normal cells in response to environmental arsenic exposure remain poorly.understood,in part due to mixed signaling pathway. elicited by.arsenic,especially.the inorganic trivalent arsenic(As3þ).

关键词： bladder pattern arsenic