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翅片管式换热器换热与压降特性的试验研究

制冷与空调 2018年第4期18卷 89-92页

作者：秋雨豪赵华英格索兰亚太工程技术中心

通过工程应用实例,选取市场上最常用的一类翅片管式换热器,针对不同的管排数和翅片间距,对其换热以及压降性能进行试验研究,并针对换热性能的差异对空调系统的影响进行分析评估。研究结果对于空调系统的研发过程具有一定的指导意义。

关键词：翅片管式换热器换热性能压降

皮层成熟度对血氧水平依赖性反应的影响:使用功能性磁共振成像对儿童视觉皮层的研究

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世界核心医学期刊文摘（儿科学分册） 2005年第7期1卷 51-52页

作者： Marcar V.L. Strssle A.E. Loenneker t. 虎小毅 University of Zürich Institute of Psychology Neuropsychology Treichlerstrasse 10 CH-8032 Zürich Switzerland Dr.

We performed blood oxygenation level-dependent (BOLD)-functional MR imaging in 11 children younger than 5 y of age and 10 children older than 5 y of *** but five of the children in the older age group were tested under light *** examined the cerebral oxidative metabolism (CMRO2) associated with the processing of a flashed and a reversing checkerboard *** stimuli had been shown in a previous study to induce identical vascular *** reversing checkerboard activated twice the neuronal population of the flashed checkerboard, doubling the CMRO2 associated with *** compared the extent of activation for the positive BOLD response and found that it did not differ between the different age *** estimated the oxidative metabolism by examining the change in the local deoxyhemoglobin (HbR)-concentration using Δ*** both stimuli induced the same vascular response, any increase in oxygen requirement would have to bemet by the identical blood *** CMRO2 will therefore result in an increase in the oxygen extraction fraction (OEF), which raises the local HbR *** the younger children, both checkerboard stimuli produced identical, high HbR *** the older children, the HbR concentration to the flashed stimulus was significantly lower than to the reversing *** conclude that, for identical stimuli, the oxidative energy requirement associated with the cortical processing is higher in young children than in older children because the presence of superfluous synaptic connections in the immature visual system activates a larger neuronal population.

关键词：血氧水平依赖性视觉皮层去氧血红蛋白成熟度血管反应突触连接盘状需氧量氧化代谢视觉系统

1型Hermansky-Pudlak综合征的黑色素细胞痣中运输缺陷的超微结构特征显著

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世界核心医学期刊文摘（皮肤病学分册） 2005年第11期1卷 17-18页

作者： Natsuga K. Akiyama M. Shimizu t. 李政霄 Dr.Department of Dermatology Hokkaido University Graduate School of Medicine North 15West 7 Kita-ku Sapporo 060-8638 Japan

Hermansky-Pudlak syndrome (HPS) is an autosomal recessive disorder characterized by oculocutaneous albinism, a bleeding disorder, and ceroid lipofuscinosis in the lungs and gut. HPS is genetically heterogeneous and the most common variant, HPS type 1, is caused by mutations in HPS1 gene. the protein encoded by HPS1 is considered to facilitate the trafficking of melanocyte-specific gene products into the premelanosome. We report the ultrastructural findings in a melanocytic nevus seen in a 17-y-old Japanese female patient with HPS1 who is a compound heterozygote of HPS1 mutations, including a novelmutation. Electronmicroscopy of a pinkish papule corresponding to the melanocytic nevus revealed markedly aberrant, immature melanosomes, large membranous structures, and giant melanosomes in the vicinity of trans-Golgi network, the characteristic abnormalities because of protein trafficking defects in HPS1. these ultrastructural features were far more clearly demonstrated in the nevus cells than in the epidermal melanocytes. thus, ultrastructural analysis of nevus cells may be an additional diagnostic tool for HPS1 and could give us important clues to further understanding of the pathomechanisms of HPS.

关键词：黑色素细胞超微结构特征脂褐质红色丘疹眼皮肤白化病复合杂合子基因突变特异性基因黑素膜结构

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对卵巢癌患者行化疗的观点

世界核心医学期刊文摘（妇产科学分册） 2005年第1期1卷 50-51页

作者： Penson R.t. Dignan F. Seiden M.V 王刚 Division of Hematology a nd Oncology Department of Medicine Massachusetts Gen. Hospital 02114 Boston MA United States

Background. Recurrent ovarian cancer (OVCA) has become the model for ca ncer as a chronic disease, yet little is known about what motivates patients and physic ians in treatment choices. Methods. We investigated the attitudes of patients wi th epithelial OVCA and staff towards palliative chemotherapy for recurrent OVCA with a cross-sectional questionnaire study. Results. Instruments were developed and piloted in 15 patients. this exploratory study reflects substantial bias in the sample populations. One hundred twenty-two patients and 37 staff were enro lled in the US and 39 patients and 25 staff were enrolled in the UK. UK patients had a lower educational status (P = 0.001), lower stage disease (P = 0.025), an d less prior lines of chemotherapy (P tients had recurrent OV CA and 67%of staff were physicians. Seventy-three percent of patients recalled a discussion about prognosis and 74%wanted to know details of the prognosis fo r a typical patient (US = UK). Most patients (48%) thought that their physician was realistic, and 57%of staff felt that they were optimistic. the vastmajorit y of both staff and patients thought that patients positively reinterpreted what they were told. Five percent of staff thought that palliative care was incomp atiblewhen considering chemotherapy as an option for their second recurrence o f OVCA, compared with 36%of US patients, significantly more than the 12%of UK patients (P = 0.007). Patients thought that standard chemotherapy for a second r ecurrence of OVCA produced remission in 50%and cure in 15%of patients. Staff r eported 20%and 0%, respectively. Fifty percent of patients and 57%of staff wo uldwant chemotherapy as an asymptomatic patient with a normal Ct and a rising CA -125. Patients generally appear to be very tolerant of grade II chemotherapy-i nduced toxicity with staff being less tolerant than patients of nausea, anorexia , diarrhea, and rash. Staff rated life prolongation by 3 months to 1 year very m uch

关键词：复发性卵巢癌姑息性治疗姑息化疗标准化疗横断面调查慢性疾病生命延续无症状患者毒性反应探索性研究

Fe—Nb—C系中γ/γ+NbCx的相边界

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金属学报 1988年第1期 114-118页

作者：洪彦若北京钢铁学院研究生院教授

Nb是高强低合金钢的一个重要的微合金化元素。它与C,N及其它化合物在奥氏体中溶解度的大小,都直接影响钢的性能。了解γ/γ±NbC_x的平衡相边界,即溶度积〔Nb〕〔C〕~x很有必要,但目前已知的一批溶度积数据分歧很大,例如,

关键词： Fe-Nb-C系 NbC_x 非化学计量化合物相边界

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日本与英国帕金森病患者的睡眠障碍比较研究

世界核心医学期刊文摘（神经病学分册） 2005年第10期1卷 38-39页

作者： Abe K. Hikita t. Sakoda S. 谢琰臣 Department of Neurology Osaka University Graduate School of Medicine D-4 2-2 Yamadaoka Suita Osaka 565-0871 Japan

Sleep disorders are common in the general population and occur more frequentl y with advancing age. However, patients with Parkinson’ s disease (PD) have bee n known to have various sleep disturbances beyond those to be expected from the effect of aging alone. We tried to quantify the various aspects of nocturnal sle ep problems in PD using the PD sleep scale (PDSS). 64 patients with PD and 60 ag e- and sex- matched controls completed the PDSS. After neurological examinatio ns, we assessed the degree of sleep disorder by the PDSS. We evaluated the sever ity of PD by the Hoehn and yahr Scale and the unified PD rating scale (UPDRS). t o compare the various aspects of nocturnal sleep problems in PD between in Japan and in the United Kingdom (UK), we refe renced and compared our results with those by Chaudhui et al. the PDSS scores in PD group were significantly different from those in controls. Individual items of the scale showed good discriminatory power between PD and controls. Overall t endencies were the same in Japan and in the UK, but there were some different po ints, especially absence of refreshing quality of sleep in Japan. We believe tha t the PDSS provides an objective method for targeted therapeutic approaches for the treatment of disturbed sleep in PD even among countries with different cultu res, such as Japan and the UK.

关键词：帕金森病睡眠障碍睡眠量定量研究试验结果等级量表靶向

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正常阴道分娩后肛门括约肌的定量肌电图评价

世界核心医学期刊文摘（妇产科学分册） 2005年第9期1卷 40-41页

作者： Gregory W.t. Stuyvesant A. Clark A.L. 王雅楠 Obstetrics and Gynecology Div. Urogynecol./Reconstr. Pelvic S. Oregon Health and Science University 3181 SW Sam Jackson Park Road Portland OR 97239 United States Dr.

OBJECtIVE: Fecal incontinence in women is thought to be associated with sphi nc ter laceration or pudendal nerve damage. A prolonged pudendal nerve terminal mot or latency is evidence of profound nerve damage, but pudendal nerve terminal mot or latency can be normal even when nerve injury has been sustained. We performed quantitative electromyography (EMG) to compare multiple motor unit action poten tial parameters between recently postpartum women and nulliparous women. MEtHODS : Standardized examinations were prospectively performed on 2 groups: 1) healthy nulliparous women without pelvic floor disorders (n=28) and 2) asymptomatic wom en who were postpartum following vaginal delivery of their first child (n = 23). the examinations included pelvic organ prolapse quantification measurements, e ndoanal ultrasonography, pudendal nerve terminal motor latency, sacral reflexes, and concentric needle EMG using multiple motor unit action potential analysis. RESULtS: A mean of 11.5 (standard deviation [SD] 1.1) weeks had elapsed since fi rst vaginal deliveries in the postpartum group. the mean fetal weight at deliver y was 3,495 (SD 458) grams. there were no sphincter defects seen by ultrasonogra phy. Compared with the nulliparous women, pudendal nerve terminal motor latency and sacral reflexes (clitoral-anal reflex, urethral-anal reflex) were not incr eased in the postpartum group. Each of the quantitative parameters (duration, am plitude, area, turns, and phases), measured from motor unit action potentials in the postpartum group, were larger than in the nulliparous group (P ≤.004, nest ed analysis of variance [ANOVA]). CONCLUSION: Quantitative EMG using multiple mo tor unit action potential analysis can detect the presence after vaginal childbi rth of subtle nerve injury not demonstrable by pudendal nerve terminal motor lat ency. Even asymptomatic women show evidence of pelvic floor nerve injury after u ncomplicated deliveries.

关键词：阴道分娩会阴神经电冲动经产妇未产妇正常分娩盆腔器官动作电位大便失禁常规检查

香港儿童参与体能活动状况及自觉体能能力探讨(英文)

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教育生物学杂志 2014年第1期2卷 21-24页

作者：张小燕麦婉鸣香港浸会大学体育学系马歇尔大学运动科学运动与休闲系

目地探讨香港儿童参与体能活动的状况及与自觉体能能力的关系。方法共有1 012名儿童参与调查,其中男527人,女483人,年龄9~14岁。采用儿童体能活动问卷及自觉体能能力量表调查儿童参与体能活动的模式及其自觉体能能力情况。运用描述性统... 详细信息

目地探讨香港儿童参与体能活动的状况及与自觉体能能力的关系。方法共有1 012名儿童参与调查,其中男527人,女483人,年龄9~14岁。采用儿童体能活动问卷及自觉体能能力量表调查儿童参与体能活动的模式及其自觉体能能力情况。运用描述性统计、t检验、多因素方差分析及Pearson相关分析等对数据进行统计分析。结果 6.6%的儿童每日进行体能活动,而21.3%未进行体能活动。最为普及的体能活动为步行、追逐、跑步、羽毛球和乒乓球。不同年龄组别自觉体能能力评分差异有统计学意义,儿童体能活动与自觉体能能力呈正相关关系。结论儿童愈多进行体能活动,其自觉体能能力愈高。

关键词：自觉体能能力体能活动儿童

百令胶囊对慢性肾脏病患者相关炎性因子的影响

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中国基层医药 2017年第21期24卷 3242-3245页

作者：马西臣彭君谭玉利日照市人民医院肾内科山东省日照276826 日照市中心医院肾内科山东省日照276800

目的观察百令胶囊对慢性肾脏病（CKD）患者超敏C反应蛋白（hs-CRP）、白细胞介素18（IL-18）、肿瘤坏死因子α（tNF-α）的影响。方法56例早期CKD患者，采用随机数字表法分为对照组（28例）及治疗组（28例），另选20名健康体检者作为健... 详细信息

目的观察百令胶囊对慢性肾脏病（CKD）患者超敏C反应蛋白（hs-CRP）、白细胞介素18（IL-18）、肿瘤坏死因子α（tNF-α）的影响。方法56例早期CKD患者，采用随机数字表法分为对照组（28例）及治疗组（28例），另选20名健康体检者作为健康对照组，治疗组在常规治疗基础上加用百令胶囊每次4粒口服，每天3次，共12周，治疗前、后分别检测hs-CRP、IL-18、***、BUN及Scr。结果对照组及治疗组CKD患者its—CRP、tNF-α、IL-18、BUN及Scr治疗前明显高于健康对照组[（5．99±2．67）、（6．17±2．23）mg／L比（2．27±2．16）mg／L，（4J4．43±7．54）、（46．54±8．63）μg／[．比（11．42±3．32）μg／L，（95．22±34．65）、（105．48±33．25）mmol／L比（21．34±10．10）ng／L，（6．86±2．97）、（6．89±2．85）．mmol／L比（5．32±2．43）mmol／L，（98．47±28．85）、（95．46±27．83）μmol／L比（75．454-28．20）μmol／L，均P〈0．05]，对照组12周后其hs-CRP、IL-18、tNF-α、Scr及BUN均有所降低，但差异无统计学意义（t=-0．22、-1．30、-1．75、-0．67、-1．16，均P〉0．05），而治疗组治疗后其***、IL-18、tNF-α及Scr明显降低（t=-2．77、-3．81、-4．71、-2．06，均P〈0．05）。结论百令胶囊能有效改善CKD患者的微炎症状态，延缓CKD的进展。

关键词：百令胶囊慢性肾脏病炎性因子