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Delineating the rice crop activities in Northeast China through regional parametric synthesis using satellite remote sensing time-series data from 2000 to 2015

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Journal of Integrative Agriculture 2021年第2期20卷 424-437页

作者： CAO Dan FENG Jian-zhong BAI Lin-yan xun lan JING Hai-tao SUN Jin-ke ZHANG Jia-hua Key Laboratory of Digital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100094P.R.China University of Chinese Academy of Sciences Beijing 100094P.R.China Agricultural Information Institute Chinese Academ y of Agricultural SciencesBeijing 100081P.R.China School of Surveying and land Information Engineering Henan Polytechnic UniversityJiaozuo 454000P.R.China

Accurate rice area extraction and yield simulations are important for understanding how national agricultural policies and environmental issues affect regional spatial changes in rice farming. In this study, an improved regional parametric syntheses approach, that is, the rice zoning adaptability criteria and dynamic harvest index(RZAC-DHI), was established, which can effectively simulate the rice cultivation area and yield at the municipal level. The RZAC was used to extract the rice area using Moderate Resolution Imaging Spectroradiometer time-series data and phenological information. The DHI was calculated independently, and then yield was obtained based on the DHI and net primary productivity(NPP). Based on the above results, we analyzed the spatial–temporal patterns of the rice cultivation area and yield in Northeast China(NEC) during 2000–2015. The results revealed that the methods established in this study can effectively support the yearly mapping of the rice area and yield in NEC, the average precisions of which exceed 90 and 80%, respectively. The rice planting areas are mainly located on the Sanjiang, Songnen and Liaohe plains, China, which are distributed along the Songhua and Liaohe rivers. The rice cultivation area and yield in this region increased significantly from 2000 to 2015, with increases of nearly 58 and 90%, respectively. The rice crop area and yield increased the fastest in Heilongjiang Province, China, whereas small changes occurred in Jilin and Liaoning provinces, China. Their gravity centers exhibited evident northward and eastward shifts, with offset distances of 107 and 358 km, respectively. Moreover, Heilongjiang Province has gradually become the new main rice production region. The methodologies used in this study provide a valuable reference for other related studies, and the spatial-temporal variation characteristics of the rice activities have raised new attention as to how these shifts affect national food security and resource al

关键词： RZAC dynamic HI rice cultivation area yield spatial-temporal change

Tenidap is neuroprotective in a pilocarpine rat model of temporal lobe epilepsy

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Chinese Medical Journal 2013年第10期126卷 1900-1905页

作者： TANG Xing-hua WU xun-yi XU lan FANG You-xin WANG Jian-hong ZHU Guo-xing HONG Zhen Department of Neurology Huashan Hospital Fudan UniversityShanghai 200040 China

Background Tenidap is a liposoluble non-steroidal anti-inflammatory drug that is easily distributed in the central nervous system and also inhibits the production and activity of cyclooxygenase-2 （COX-2） and cytokines in vitro. This study aimed to evaluate the neuroprotective effect of tenidap in a pilocarpine rat model of temporal lobe epilepsy （TLE）. Methods Tenidap was administered daily at 10 mg/kg for 10 days following pilocarpine-induced status epilepticus （SE） in male Wistar rats after which prolonged generalized seizures resulted in TLE. After tenidap treatment, spontaneous recurrent seizures （SRSs） were recorded by video monitoring （for 7 hours per day for 14 days）. The frequency and severity of the SRSs were observed. Histological and immunocytochemical analyses were used to evaluate the neuroprotective effect of tenidap and detect COX-2 expression, which may be associated with neuronal death. Results There were 46.88±10.70 survival neurons in tenidap-SE group, while there were 27.60±5.18 survival neurons in saline-SE group at -2.4 mm field in the CA3 area. There were 37.75±8.78 survival neurons in tenidap-SE group, while there were 33.40±8.14 survival neurons in saline-SE group at -2.4 mm field in the CA1 area. Tenidap treatment significantly reduced neuronal damage in the CA3 area （P 〈0.05） and slightly reduced damage in the CA1 area. Tenidap markedly inhibited COX-2 expression in the hippocampus, especially in the CA3 area. Conclusion Tenidap conferred neuroprotection to the CA3 area in a pilocarpine-induced rat model of TLE by inhibiting COX-2 expression.

关键词： tenidap cyclooxygenase-2 inhibitors temporal lobe epilepsy

Combination of AAV-delivered tumor suppressor PTEN with anti-PD-1 loaded depot gel for enhanced antitumor immunity

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Acta Pharmaceutica Sinica B 2024年第1期14卷 350-364页

作者： Yongshun Zhang lan Yang Yangsen Ou Rui Hu Guangsheng Du Shuang Luo Fuhua Wu Hairui Wang Zhiqiang Xie Yu Zhang Chunting He Cheng Ma Tao Gong Ling Zhang Zhirong Zhang xun Sun Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial TechnologyWest China School of PharmacySichuan UniversityChengdu 610041China Med-X Center for Materials College of Polymer Science and EngineeringSichuan UniversityChengdu 610065China

Recent clinical studies have shown that mutation of phosphatase and tensin homolog deleted on chromosome 10(PTEN)gene in cancer cells may be associated with immunosuppressive tumor microenvironment(TME)and poor response to immune checkpoint blockade(ICB)***,efficiently restoring PTEN gene expression in cancer cells is critical to improving the responding rate to ICB ***,we screened an adeno-associated virus(AAV)capsid for efficient PTEN gene delivery into B16F10 tumor *** demonstrated that intratumorally injected AAV6-PTEN successfully restored the tumor cell PTEN gene expression and effectively inhibited tumor progression by inducing tumor cell immunogenic cell death(ICD)and increasing immune cell ***,we developed an anti-PD-1 loaded phospholipid-based phase separation gel(PPSG),which formed an in situ depot and sustainably release anti-PD-1 drugs within 42 days in *** order to effectively inhibit the recurrence of melanoma,we further applied a triple therapy based on AAV6-PTEN,PPSG^(@anti-PD-1)and CpG,and showed that this triple therapy strategy enhanced the synergistic antitumor immune effect and also induced robust immune memory,which completely rejected tumor *** anticipate that this triple therapy could be used as a new tumor combination therapy with stronger immune activation capacity and tumor inhibition efficacy.

关键词： Triple therapy Adeno-associated virus PTEN PPSG@anti-PD-1 CpG Immunogenic cell death Antitumor immune response Immune memory

The 8^(th) Sino-German Seminar on Human Rights

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International Understanding 2006年第4期 28-29页

作者： Zhong xun Xiao lan

“文化幻象”与“文化实体”之间——金斯伯格诗中的中国观

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外国文学研究 2007年第6期29卷 90-96页

作者：苏晖陈兰薰华中师范大学文学院

美国"垮掉派"代表诗人金斯伯格在其一系列诗歌中对中国进行了描绘,早期创作倾向于把文化想象投射到中国,借推崇中国古代文明反思美国文化以及人类命运;1984年10月作为美国作家代表团成员来到中国后,写下了"一天早晨,我在中国漫步"、"读... 详细信息

美国"垮掉派"代表诗人金斯伯格在其一系列诗歌中对中国进行了描绘,早期创作倾向于把文化想象投射到中国,借推崇中国古代文明反思美国文化以及人类命运;1984年10月作为美国作家代表团成员来到中国后,写下了"一天早晨,我在中国漫步"、"读白居易抒怀"等诗篇,对于中国的描绘从"文化幻象"转向"文化实体",表现出对中国工人、农民生存状态的关注和对中国摆脱贫穷落后面貌的期待与展望,蕴涵着诗人对中国真挚的情感和对中国历史与现状的认识与反思。当然,他对于"异"文化中国的认识和理解仍然无法进入到很深的层面,显示出在"文化幻象"与"文化实体"之间的徘徊。金斯伯格中国观的形成及其发展变化,有着深刻的社会历史背景和心理原因,对于西方人认识和了解中国以及中国人反省和完善自身都有着重要的意义。

关键词： “垮掉的一代” 金斯伯格中国观

基于SMOTE和Inception-CNN的种植和组培金线莲鉴别

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光谱学与光谱分析 2024年第1期44卷 158-163页

作者：蓝艳王武许文柴琴琴李玉榕张勋福州大学电气工程与自动化学院福建福州350108 福建中医药大学药学院福建福州350122

金线莲是一种珍贵中药材,其治疗、保健作用十分显著。金线莲培育方式主要有种植、组培等,不同培育方式的金线莲,在性状上仅表现出细微差异,但药用、市场价值差异显著,培育方式鉴别能有效保证药用疗效、维护良好市场秩序,然而由于不同品... 详细信息

金线莲是一种珍贵中药材,其治疗、保健作用十分显著。金线莲培育方式主要有种植、组培等,不同培育方式的金线莲,在性状上仅表现出细微差异,但药用、市场价值差异显著,培育方式鉴别能有效保证药用疗效、维护良好市场秩序,然而由于不同品系、产地、培育时间等复合差异的影响,增加了培育方式鉴别难度与复杂度。提出一种基于改进1D-Inception-CNN模型的金线莲培育方式鉴别方法。采用近红外光谱仪采集种植、组培金线莲的光谱,首先使用合成少数类过采样技术(SMOTE)进行过采样以解决种植品、组培品样本比例不平衡问题,其次构建基于改进Inception结构的一维卷积神经网络对来自不同品系、产地、培育时间的金线莲进行种植品、组培品鉴别,最后采用贝叶斯优化方法对构建的卷积神经网络模型超参数进行优化;最终五折交叉验证平均鉴别准确率、精确率、召回率、综合评价指标高达97.95%、 96.16%、 100%、 98.02%。研究表明,实验提出的鉴别模型为快速鉴别金线莲种植品、组培品提供一种有效方法。

关键词：金线莲少数类过采样技术 Inception模块一维卷积神经网络贝叶斯优化

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我国区域商贸物流现代化水平实证测度

商业经济研究 2020年第13期 105-108页

作者：蓝勋广西财经学院广西南宁530003

加快发展商贸物流业,提升商贸物流现代化水平,对于稳增长、促改革、调结构、扩就业具有重要的现实意义。因此,本文通过构建综合评价模型,对广西商贸物流现代化水平进行实证测度,旨在为各地提升商贸物流现代化水平提供指导依据。结果表明... 详细信息

加快发展商贸物流业,提升商贸物流现代化水平,对于稳增长、促改革、调结构、扩就业具有重要的现实意义。因此,本文通过构建综合评价模型,对广西商贸物流现代化水平进行实证测度,旨在为各地提升商贸物流现代化水平提供指导依据。结果表明:2019年,广西商贸物流产业大专以上学历指标综合评价得分为59.12,分值低于其他指标;信息技术现代化指标综合评价得分由2009年的5.16提高为2019年的82.37;2015年,广西家庭互联网端口接入数显著提升,有效提高了广西的信息技术现代化水平。在2009-2019年,广西商贸物流现代化有关指标综合评价得分逐年上升。

关键词：商贸物流现代化水平物流产业信息技术现代化电子商务交易

不同能区核-核碰撞实验中高多重数,大起伏的事件性质的分析——与物理模型无关的统计分析

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高能物理与核物理 2006年第2期30卷 94-98页

作者：兰洵钱琬燕蔡勖华中师范大学物理科学与技术学院武汉430079

报道了用不依赖于任何物理模型的纯数理统计的方法对EMU01买验组200AGeV的32S与固定的Au靶碰撞中较高多重数和较大起伏事例的数据和STAR实验组在核核质量中心能量为 (SNN)/(1/2)=200GeV的Au+Au碰撞中较高多重数和较大起伏事例的数据所... 详细信息

报道了用不依赖于任何物理模型的纯数理统计的方法对EMU01买验组200AGeV的32S与固定的Au靶碰撞中较高多重数和较大起伏事例的数据和STAR实验组在核核质量中心能量为 (SNN)/(1/2)=200GeV的Au+Au碰撞中较高多重数和较大起伏事例的数据所做的分析．对3个相差很远的能区——固定靶加速器能区,核-核对撞机能区以及宇宙线能区所得的分析结果进行了比较,并对所得的结果进行了讨论．

关键词：稳定分布稳定性平稳性标度无关性全局统计依赖性

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尿素/过硫酸钠纸基微流体燃料电池产电特性

工程热物理学报 2024年第2期45卷 525-534页

作者：陈曦叶丁丁朱恂杨扬兰巧陈蓉廖强重庆大学低品位能源利用技术及系统教育部重点实验室重庆400030 重庆大学能源与动力工程学院工程热物理研究所重庆400030

本文提出一种尿素/过硫酸钠完全被动式纸基微流体燃料电池,通过方波电流法将非贵金属镍催化剂电沉积到碳纸上制备阳极,阴极无需催化剂负载,电池成本大大降低。在不同结构及燃料、氧化剂、电解液浓度下测试了电池性能,结果表明,双层纸结... 详细信息

本文提出一种尿素/过硫酸钠完全被动式纸基微流体燃料电池,通过方波电流法将非贵金属镍催化剂电沉积到碳纸上制备阳极,阴极无需催化剂负载,电池成本大大降低。在不同结构及燃料、氧化剂、电解液浓度下测试了电池性能,结果表明,双层纸结构能大幅提高反应物流速,强化反应物传质,提高性能;电池在电极间距为6 mm、燃料浓度为0.3 mol·L^(-1)、氧化剂和电解液浓度均为1.0 mol·L^(-1)时,峰值功率密度和极限电流密度分别为5.9 m W·cm^(-2)和23.5 m A·cm^(-2),且运行稳定性较好。

关键词：尿素/过硫酸钠纸基微流体燃料电池性能稳定性