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An Effective Approach for the Preparation of High Performance Thermal Conductive Polymer Composites Containing Liquid Metal

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Chinese Journal of Polymer Science 2024年第7期42卷 992-1001,I0010页

作者： Xin Chen xue-Zhong Zhang yi-Fei Yuan Chuan-Liang Chen Lian-Hu Xiong Qiang Fu Hua Deng College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan UniversityChengdu610065China Department of Materials Science and Engineering Sichuan University-Pittsburgh InstituteSichuan UniversityChengdu610065China

The preparation of high-performance thermal conductive composites containing liquid metals(LM)has attracted significant ***,the stable dispersion of LM within polymer solution and effective property contribution of liquid metals remains significant challenges that need to be *** by the properties of the dendritic structure of the tree root system in grasping the soil,“shear-induced precipitation-interfacial reset-reprotonation”processing strategy is proposed to prepare nanocomposites based on aramid micron fibers(AMFs)with hierarchical dendritic *** to the combination of van der Waals force provided by hierarchical dendritic structure,electrostatic interaction between AMFs and LM,coordinative bonding of―NH to LM,together with interfacial re-setting and multi-step protonation,several features can be achieved through such strategy:conducive to the local filler network construction,improvement of interfacial interaction,improvement of the stability of filler dispersion in the solvent,and enhancement of mechanical and thermal properties of the *** resulting AMFsp H=4/LM films demonstrate a thermal conductivity of 10.98 W·m^(-1)·K^(-1)at 70%filler content,improvement of 126.8%compared to ANFs/LM film;while maintaining a strength of~85.88 MPa,improvement of 77%compared to AMFs/LM *** also possess insulation properties,enable heat dissipation for high power *** work provides an effective strategy for the preparation of high performance polymer composites containing liquid metal.

关键词： Shear-induced Reprotonation AMFs LM Filler dispersion

Proteomic studies of the effects of processing techniques on properties of abalone muscles: A comprehensive review

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Food Science and Human Wellness 2024年

作者： Yan Tian Shuyi you yi Zhang Baodong Zheng Hongliang Zeng College of Food Science Fujian Agriculture and Forestry University Engineering Research Center of Fujian-Taiwan Special Marine Food Processing and Nutrition Ministry of Education Key Laboratory of Marine Biotechnology of Fujian Province Institute of Oceanology Fujian Agriculture and Forestry University Fuzhou Ocean Research Institute

Background: With the increasing per capita demand for animal protein， there is a growing interest in the abundant abalone protein resources. Abalone proteins are known for their nutritional and functional properties that contribute to flavor and texture. Scope and approach: We systematically constructed the relationship between abalone protein， processing， and proteomics. This paper reviews the nutritional properties of abalone proteins and evaluates the effects of different thermal processing techniques， non-thermal processing， and freezing on abalone proteins. In addition， we synthesize published abalone proteomics studies and the use of proteomics technology to better elucidate the quality changes of abalone and its products， and as a technical basis for the study of blue food marker proteins. It is important direction to clearly explain the protein composition and meat quality mechanism of abalone in the processing and storage by *** findings and conclusions: During various types of thermal processing， non-thermal processing， and freezing of abalone， the various chemical forces between protein molecules are disrupted， which in turn leads to different degrees of denaturation， aggregation， and gelation， which may have an impact on the organoleptic properties， bioavailability， and digestibility of abalone muscle. Proteomics is used in abalone biology studies to understand developmental biology， physiology， disease/stress， and species identification and can also be a powerful tool to characterize processing methods on abalone quality properties.

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TSPO deficiency exacerbates acute lung injury via NLRP3 inflammasome-mediated pyroptosis

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Chinese Medical Journal 2024年第13期137卷 1592-1602页

作者： Jingyi Han xue Zhang Menghua Cai Feng Tian yi Xu Hui Chen Wei He Jianmin Zhang Hui Tian Department of Thoracic Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China CAMS Key Laboratory of T Cell and Immunotherapy Department of ImmunologyInstitute of Basic Medical SciencesChinese Academy of Medical Sciences and School of Basic MedicinePeking Union Medical CollegeState Key Laboratory of Medical Molecular BiologyBeijing 100005China Changzhou Xitaihu Institute for Frontier Technology of Cell Therapy ChangzhouJiangsu 213000China Haihe Laboratory of Cell Ecosystem Chinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China

Background:Acute respiratory distress syndrome(ARDS)is a common cause of respiratory failure in many critically ill *** inflammasome activation plays an important role in the induction of acute lung injury(ALI)and ARDS,the regulatory mechanism of this process is still *** cells are stimulated by inflammation,the integrity and physiological function of mitochondria play a crucial part in ***,the underlying mechanisms and function of mitochondrial proteins in the process of pyroptosis are largely not yet ***,we identified the 18-kDa translocator protein(TSPO),a mitochondrial outer membrane protein,as an important mediator regulating nucleotide-binding domain,leucine-rich repeat,and pyrin domain-containing protein 3(NLRP3)inflammasome activation in macrophages during ***:TSPO gene knockout(KO)and lipopolysaccharide(LPS)-induced ALI/ARDS mouse models were employed to investigate the biological role of TSPO in the pathogenesis of *** macrophages were used to further characterize the effect of TSPO on the NLRP3 inflammasome *** of NLRP3 inflammasome was preformed through LPS+adenosine triphosphate(ATP)co-stimulation,followed by detection of mitochondrial membrane potential,reactive oxygen species(ROS)production,and cell death to evaluate the potential biological function of *** between two groups were performed with a two-sided unpaired ***:TSPO-KO mice exhibited more severe pulmonary inflammation in response to LPS-induced *** deficiency resulted in enhanced activation of the NLRP3 inflammasome pathway,promoting more proinflammatory cytokine production of macrophages in LPS-injured lung tissue,including interleukin(IL)-1β,IL-18,and macrophage inflammatory protein(MIP)-*** in TSPO-KO macrophages tended to depolarize in response to cellular *** increased production of mitochondrial damage-associated molecular pattern led to enhanced mitochondrial membr

关键词： Acute respiratory distress syndrome Acute lung injury 18-kDa translocator protein Macrophage NLRP3 inflammasome Inflammation

Effects of loneliness and isolation on cardiovascular diseases:a two sample Mendelian Randomization Study

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Journal of Geriatric Cardiology 2024年第3期21卷 340-348页

作者： Jia-yin CAI Xin WANG Cong-yi ZHENG xue CAO Zhen HU Run-Qing GU yi-Xin TIAN Ye TIAN Lan SHAO Lin-Feng ZHANG Zeng-Wu WANG Division of Prevention and Community Health National Center for Cardiovascular DiseaseNational Clinical Research Center of Cardiovascular DiseaseState Key Laboratory of Cardiovascular DiseaseFuwai HospitalPeking Union Medical College&Chinese Academy of Medical SciencesBeijingChina

BACKGROUND Loneliness and isolation are associated with multiple cardiovascular diseases(CVDs),but there is a lack of research on whether they were causally *** conducted a Mendelian Randomization(MR)study to explore causal relationships between loneliness and isolation and multiple *** Single nucleotide polymorphisms associated with loneliness and isolation were identified from a genome-wide association study(GWAS)of 455,364 individuals of European ancestry in the IEU GWAS *** data for 15 CVDs were also obtained from the IEU GWAS *** used three MR methods including inverse variance weighting,MR-Egger,and weighted median estimation to assess the causal effect of exposure on ***'s Q test and MR-Egger intercept test were used to evaluate the heterogeneity and *** MR analysis showed that loneliness and isolation were significantly associated with essential hypertension(OR=1.07,95%CI:1.03-1.12),atherosclerotic heart disease(OR=1.04;95%CI:1.02-1.06),myocardial infarction(OR=1.02;95%CI:1-1.04)and angina(OR=1.04;95%CI=1.02-1.06).No heterogeneity and pleiotropy effects were found in this *** Causal relationship of loneliness and isolation with CVDs were found in this study.

关键词： diseases cardiovascular angina

Electrostatic Encapsulation of Cobalt Ions into Crystalline Framework Derived Polymer Aerogel:Ultra-light,Pressure Resistant,Hydrophobic,Photothermal Conversion,Heat Insulation and Infrared Stealth

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Chinese Journal of Polymer Science 2024年第7期42卷 946-957,I0007页

作者： yi-Fan Kang Jin-Lu Tang Ming Song Wei Wang Jia-Cheng Ma Zhan-you Ji Tong Liu Wen-Huan Huang China Key Laboratory of Chemical Additives for China National Light Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and TechnologyXi’an710021China College of New Energy Xi’an Shiyou UniversityXi’an710065China Xi’an Key Laboratory of Functional Supramolecular Structure and Materials College of Chemistry and Materials ScienceNorthwest UniversityXi’an710127China

A variety of electromagnetic wave absorption materials(EMWAs)have been reported,but the integration of powder materials and multifunctional devices should be investigated in-depth to adapt to practical ***,carbon-coated cobalt composites were prepared by adsorbing magnetic metal cations into an anionic crystalline framework through an electrostatic encapsulate *** reflection loss(RL_(min))of-40.49 d B and effective absorption bandwidth(EAB)of 5.36 GHz(RL<-10 d B,10.4-15.76 GHz)was achieved with an optimal radar cross section(RCS)reduction of 34.9 dB·m^(2) for the sample *** commercial applications,Co@CN-4 was integrated into sodium carboxymethyl cellulose(CMC)aerogel to create an ultra-lightweight composite aerogel that is compressive resistant and heat-holding while also having photothermal conversion *** hydrophobic modification makes it more widely *** study provides a new strategy for EWAMs to integrate versatility and improve their application prospects.

关键词： Electrostatic incorporation Magnetic nanoparticle Co@CN composites Electromagnetic wave absorbing Metal-organic framework

A new 3D plastoelastohydrodynamic lubrication model for rough surfaces

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Friction 2024年第6期12卷 1176-1193页

作者： Shengyu you Jinyuan TANG Qiang WANG State Key Laboratory of Precision Manufacturing for Extreme Service Performance Central South UniversityChangsha 410083China

Plastoelastohydrodynamic lubrication of rough surfaces(R-PEHL)is a cutting-edge area of research in interface fluid-structure coupling *** existing R-PEHL model calculates the elastic-plastic deformation of rough surface by the Love equation in a semi-infinite space smooth surface,which deviates from the actual ***,it is an innovative work to study the exact solution of elastic-plastic deformation of rough surface and its influence on the solution results of R-PEHL *** this paper,a new contact calculation model of plastoelastohydrodynamic lubrication(PEHL)with three-dimensional(3D)rough surface is proposed by integrating numerical method of EHL and finite element *** new model eliminates an original error introduced by the assumption of semi-infinite space in contact calculation,providing wide applicability and high *** the given rough surfaces and working conditions,the study reveals that:(1)the oil film pressure calculated by the new model is lower than that of the smooth surface in semi-infinite space by 200–800 MPa;(2)the Mises stress of the new model is 2.5%–26.6%higher than that of the smooth surface in semi-infinite space;(3)compared with the semi-infinite space assumption,the rough surface plastic deformation of the new model is increased by 71%–173%,and the local plastic deformation singularity may appear under the semi-infinite space assumption;(4)the plastic deformation caused by the first contact cycle on the rough surface of the new model accounts for 66.7%–92.9%of the total plastic deformation,and the plastic deformation of the semi-infinite space accounts for 50%–83.3%.This study resolves the contradiction between the smooth surface assumption and the rough surface in the existing R-PEHL model,establishing a solid logic foundation for the accurate solution of R-PEHL model.

关键词： rough surface plastoelastohydrodynamic lubrication(PEHL) asperity plastic deformation semi-infinite space

Association of Methionine Synthase rs1805087 Polymorphism With Arsenic-Related Skin Pigmentary Changes:A Population-Based Case-Control Study

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International Journal of Dermatology and Venereology 2024年第2期7卷 70-77页

作者： Xiao-Yan Huang yi Xiao Dan-Rong Jing Min-xue Shen Li-Xia Lu Department of Pathology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Department of Dermatology Xiangya HospitalCentral South UniversityChangshaHunan 410008China Hunan Key Laboratory of Skin Cancer and Psoriasis Central South UniversityChangshaHunan 410008China Hunan Engineering Research Center of Skin Health and Disease Central South UniversityChangshaHunan 410008China Department of Social Medicine and Health Management Xiangya School of Public HealthCentral South UniversityChangshaHunan 410008China

Objective:Chronic arsenic exposure causes skin lesions including skin cancers,pigmentary changes,and *** polymorphism in arsenic metabolism may increase susceptibility to the development of arsenic-related skin *** study was performed to determine whether arsenic metabolism-related gene variants are associated with arsenic-related pigmentary ***:This case-control study involved 189 patients with arsenic-related pigmentary changes and 103 ***-eight polymorphisms in 10 genes determined by mass spectrometry assay served as candidate drivers of arsenic-induced pigmentary *** and plasma arsenic levels were determined by inductively coupled plasma mass *** arsenic concentrations were measured by nondispersive atomic fluorescence *** metabolites in urine were determined using high-performance liquid chromatography with inductively coupled plasma mass *** folate was measured using a folate radio assay *** of variance,nonparametric test,or the chi-square test was selected according to the data *** correlation analysis was used to determine the correlation between two *** regression was used to estimate the effect of single-nucleotide ***:The arsenic concentrations in urine,plasma,and hair and the urine arsenic species were not significantly different between patients and *** regression revealed that among the polymorphisms,the methionine synthase(MTR)rs1805087 polymorphism showed a protective effect against arsenic-related pigmentary *** the codominant model,the adjusted odds ratio for age,sex,and ethnicity was 0.41(95%confidence interval[CI],0.21-0.80;P=0.008)for the AG genotype and 0.11(95%CI,0.02-0.60;P=0.012)for the GG ***:MTR polymorphism showed a protective effect against arsenic-related pigmentary changes in the logistic regression *** effect of MTR rs1805087 might

关键词： methionine synthase arsenic-related pigmentary changes arsenic metabolism

Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice

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Zoological Research 2024年第3期45卷 663-678页

作者： Li-Rong Liang Bing Liu Shu-Hui Cao you-yi Zhao Tian Zeng Mei-Ting Zhai Ze Fan Dan-yi He San-Xin Ma Xiao-Tong Shi Yao Zhang Hui Zhang State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration National Clinical Research Center for Oral DiseasesShaanxi Engineering Research Center for Dental Materials and Advanced ManufactureDepartment of AnesthesiologySchool of StomatologyAir Force Medical UniversityXi’anShaanxi 710032China Department of Anesthesiology 986th Air Force HospitalAir Force Medical UniversityXi’anShaanxi 710032China

A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive ***,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive ***,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly *** this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal *** neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral *** indicated that ADNP was significantly down-regulated following developmental exposure to *** adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine ***,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane ***-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by *** analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic *** of Wnt signaling was restored in the davunetide-treated ***,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general *** study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal

关键词： Davunetide Sevoflurane Abnormal social behaviors ADNP Neurotoxicity

Data-Driven Control of Linear Systems via Quantized Feedback

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Journal of Systems Science & Complexity 2024年第1期37卷 152-168页

作者： LI Xingchen ZHAO Feiran you Keyou Department of Automation and BNRist Tsinghua UniversityBeijing 100084China

Quantized feedback control is fundamental to system synthesis with limited communication *** sharp contrast to the existing literature on quantized control which requires an explicit dynamical model,the authors study the quadratic stabilization and performance control problems with logarithmically quantized feedback in a direct data-driven framework,where the system state matrix is not exactly known and instead,belongs to an ambiguity set that is directly constructed from a finite number of noisy system *** this end,the authors firstly establish sufficient and necessary conditions via linear matrix inequalities for the existence of a common quantized controller that achieves our control objectives over the ambiguity ***,the authors provide necessary conditions on the data for the solvability of the LMIs,and determine the coarsest quantization density via semi-definite *** theoretical results are validated through numerical examples.

关键词： Data-driven control linear matrix inequalities linear systems quantized control.