检索结果-南通市图书馆

Effect of vibration frequency on primary phase and properties of grey cast iron fabricated by lost foam casting

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2020年第1期17卷 1-7页

作者： Bo-tao Xiao Zi-tian Fan Wen-ming Jiang Jun-huai Xiang xue-fang yan Jiangxi Key Laboratory of Surface Engineering Jiangxi Science and Technology Normal UniversityNanchang 330013China State Key Laboratory of Material Processing and Die&Mould Technology Huazhong University of Science&TechnologyWuhan 430074China

The properties of gray cast iron(GCI)are affected by density of matrix,size of flake graphite and primary *** this paper,the Y-type specimen of GCI was prepared by lost foam casting(LFC)with and without vibration,and the influence of vibration frequency on the density of matrix,size of primary phase,and properties of the GCI was *** results show that the length of the flake graphite and the size of the primary austenite in GCI firstly decrease and then increase with the increase of the vibration *** a vibration frequency of 35 Hz,the length of the flake graphite is the shortest,the primary austenite is the finest and the density of the matrix is the *** addition,the tensile strength,elongation and hardness of the GCI firstly increase and then decrease with the increase of the vibration frequency,due to the refinement of the primary phase and the increase of the matrix *** order to analyze the refinement mechanism of the primary phase of the GCI fabricated by the LFC with vibration,the solidification temperature fields of the GCI fabricated by the LFC with the vibration frequency of 0 and 35 Hz were *** results show that the vibration reduces the eutectic point of the GCI and increases the supercooling degree during the eutectic *** a result,the length of the flake graphite and the size of the primary austenite in GCI fabricated by LFC with the vibration frequency of 35 Hz decrease.

关键词： vibration frequency lost foam casting grey cast iron flake graphite properties

Application of metabolomics in clinical and laboratory gastrointestinal oncology

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2021年第6期13卷 536-549页

作者： Peng Gao Xin Huang xue-yan fang Hui Zheng Shu-Ling Cai Ai-Jun Sun Liang Zhao Yong Zhang Department ofClinical Laboratory Dalian Sixth People's HospitalDalian 116031Liaoning ProvinceChina Department of Internal Medicine Dalian Sixth People's HospitalDalian 116031Liaoning ProvinceChina Department of Nursing Dalian Sixth People's HospitalDalian 116031Liaoning ProvinceChina Clinical Research Center Dalian Sixth People's HospitalDalian 116031Liaoning ProvinceChina Department of Surgery Dalian Sixth People's HospitalDalian 116031Liaoning ProvinceChina

Metabolites are versatile bioactive *** are not only the substrates and/or the products of enzymatic reactions but also act as the regulators in the systemic *** is a high-throughput analytical strategy to qualify or quantify as many metabolites as possible in the *** is an indispensable part of systems *** leading techniques in this field are mainly based on mass spectrometry and nuclear magnetic resonance *** metabolomic analysis has gained wide use in bioscience *** the tumor research arena,metabolomics can be employed to identify biomarkers for prediction,diagnosis,and *** effect evaluation and personalized medicine decision-making can also benefit from metabolomic analysis of patient biofluid or biopsy *** cell-level studies can help in disease *** this review,the basic features and principles of varied metabolomic analysis are *** value of metabolomics in clinical and laboratory gastrointestinal cancer studies is discussed,especially for mass spectrometry ***,combined use of metabolomics and other tools to solve problems in cancer practice is briefly *** summary,metabolomics paves a new way to explore cancerous diseases in the light of small molecules.

关键词： Metabolomics Biomarker Mass spectrometry Metabolite Gastrointestinal cancer Diagnosis

The interaction between KIF21A and KANK1 regulates dendritic morphology and synapse plasticity in neurons

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第1期20卷 209-223页

作者： Shi-yan Sun Lingyun Nie Jing Zhang xue fang Hongmei Luo Chuanhai Fu Zhiyi Wei Ai-Hui Tang Hefei National Research Center for Physical Sciences at the Microscale CAS Key Laboratory of Brain Function and DiseaseMinistry of Education Key Laboratory for Membrane-less Organelles and Cellular DynamicsDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina CAS Center for Excellence in Molecular Cell Sciences Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Neurobiology School of Life SciencesSouthern University of Science and TechnologyShenzhenGuangdong ProvinceChina Brain Research Center Southern University of Science and TechnologyShenzhenGuangdong ProvinceChina

Morphological alterations in dendritic spines have been linked to changes in functional communication between neurons that affect learning and ***-4 KIF21A helps organize the microtubule-actin network at the cell cortex by interacting with KANK1;however,whether KIF21A modulates dendritic structure and function in neurons remains *** this study,we found that KIF21A was distributed in a subset of dendritic spines,and that these KIF21A-positive spines were larger and more structurally plastic than KIF21A-negative ***,the interaction between KIF21A and KANK1 was found to be critical for dendritic spine morphogenesis and synaptic *** of either KIF21A or KANK1 inhibited dendritic spine morphogenesis and dendritic branching,and these deficits were fully rescued by coexpressing full-length KIF21A or KANK1,but not by proteins with mutations disrupting direct binding between KIF21A and KANK1 or binding between KANK1 and *** down KIF21A in the hippocampus of rats inhibited the amplitudes of long-term potentiation induced by high-frequency stimulation and negatively impacted the animals’cognitive *** together,our findings demonstrate the function of KIF21A in modulating spine morphology and provide insight into its role in synaptic function.

关键词： actin cytoskeleton dendrite KANK1 KIF21A microtubule spine morphology spine synaptic plasticity talin1

在线全文

学校读者我要写书评

暂无评论

高校预算编制对预算松弛影响的实证分析

新疆大学学报（哲学社会科学版） 2011年第5期39卷 13-15页

作者：龚巧莉方雪艳新疆财经大学会计学院新疆乌鲁木齐830012 安徽财贸职业学院会计系安徽合肥230601

文章在文献综述的基础上,以新疆高校为例,对高校预算编制方法、预算编制者相关工作年限以及预算参与程度影响预算松弛的问题进行了实证检验。研究结果发现:预算编制者从事相关工作时间越长其预算松弛程度越高,预算参与程度越高预算松弛... 详细信息

文章在文献综述的基础上,以新疆高校为例,对高校预算编制方法、预算编制者相关工作年限以及预算参与程度影响预算松弛的问题进行了实证检验。研究结果发现:预算编制者从事相关工作时间越长其预算松弛程度越高,预算参与程度越高预算松弛程度越高,在预算编制者的工作经验和预算参与程度的共同作用下,预算编制者相关工作时间越长、预算参与程度越高预算松弛程度越低。

关键词：高校预算松弛预算编制实证

在线全文

学校读者我要写书评

暂无评论

基于CIM的内存实时数据库的设计

计算机工程与设计 2007年第14期28卷 3508-3510页

作者：薛艳芳吴健西北工业大学计算机学院陕西西安710072

随着电力工业的发展,各个应用系统之间信息共享和应用集成需求凸现出来,迫切的需要不同系统间都遵循一个标准的、开放的电力系统信息模型,并提供通用的数据接口。CIM模型和CIS接口的出现,很好的解决了这一问题。同时由于电力行业需要存... 详细信息

随着电力工业的发展,各个应用系统之间信息共享和应用集成需求凸现出来,迫切的需要不同系统间都遵循一个标准的、开放的电力系统信息模型,并提供通用的数据接口。CIM模型和CIS接口的出现,很好的解决了这一问题。同时由于电力行业需要存储大量的有较高时间约束的数据,将数据存储在内存中,并且定期的将内存中的数据转储到硬盘数据库中,可以有效的提高数据库事务执行效率。其中基于CIM模型的数据在内存中的组织方式是设计的重心。该内存实时数据库在电力监控系统中已经投入使用,并得到了预期的效果。

关键词：监控系统 CIM模型内存实时数据库实时数据结构泛化关系关联关系聚集关系

高余维平均曲率流在第一奇异时间处的平均曲率

在线全文

学校读者我要写书评

暂无评论

信阳师范学院学报（自然科学版） 2012年第1期25卷 31-33页

作者：喻丽菊薛艳昉嘉兴学院数理与信息工程学院浙江嘉兴314001 信阳师范学院数学与信息科学学院河南信阳464000

考虑沿平均曲率向量移动的一族光滑浸入X(.,t):Mm→Rn,满足tX(x,t)=H(x,t),t∈[0,T).证明了:在第一奇异时间T处,若奇异点为第一型的,则平均曲率在T处爆破.

关键词：曲率流奇异点单调公式平均曲率

二阶离散哈密尔顿系统周期解的存在性和多解性(英文)

在线全文

学校读者我要写书评

暂无评论

西南师范大学学报（自然科学版） 2006年第1期31卷 7-12页

作者：薛艳昉唐春雷西南大学数学与财经学院重庆400715

通过临界点理论中的极小作用原理,得到了一些关于非自治二阶离散哈密尔顿系统Δ2u(t-1)=F(t,u(t))t∈Z的解的存在与多解性结果.

关键词：离散哈密尔顿系统周期解临界点极小作用原理

Prospects of elafibranor in treating alcohol-associated liver diseases

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 132-137页

作者： Wei-Tong Cui Hua-Ru xue Dian-fang Wei Xiao-Yu Feng Kai Wang School of Basic Medicine Qilu Medical UniversityZibo 255300Shandong ProvinceChina School of Medical Imaging Qilu Medical UniversityZibo 255300Shandong ProvinceChina

Alcohol-related liver disease(ALD),which is induced by excessive alcohol con-sumption,is a leading cause of liver-related morbidity and *** pa-tients exhibit a spectrum of liver injuries,including hepatic steatosis,inflam-mation,and fibrosis,similar to symptoms of nonalcohol-associated liver diseases such as primary biliary cholangitis,metabolic dysfunction-associated steatotic liver disease,and nonalcoholic *** has been approved for the treatment of primary biliary cholangitis and has been shown to improve symptoms in both animal models and in vitro cell models of metabolic dysfunc-tion-associated steatotic liver disease and nonalcoholic ***,the efficacy of elafibranor in treating ALD remains *** this article,we comment on the recent publication by Koizumi et al that evaluated the effects of elafibranor on liver fibrosis and gut barrier function in an ALD mouse *** findings indicate the potential of elafibranor for ALD treatment,but further experimental investigations and clinical trials are warranted.

关键词： Elafibranor Alcohol-associated liver diseases Peroxisome proliferator-activated receptor Lipid Apoptosis Steatosis Inflammation Fibrosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

短时微重力下气泡尾流效应的动力学特性研究

工程热物理学报 2015年第1期36卷 184-188页

作者：齐宝金魏进家赵建福薛艳芳西安交通大学动力工程多相流国家重点实验室西安710049 西安交通大学化学工程与技术学院西安710049 中国科学院力学研究所微重力重点实验室(国家微重力实验室) 北京100190

实验研究了微重力环境中,不同热流密度时尾流效应对气泡动力学过程的影响。结果表明,微重力下气泡的尾流效应比常重力时更加明显,低热流密度时尾流对气泡动力学行为影响微弱,中高热流密度时尾流影响效果显著。尾流区内液体的水平流动促... 详细信息

实验研究了微重力环境中,不同热流密度时尾流效应对气泡动力学过程的影响。结果表明,微重力下气泡的尾流效应比常重力时更加明显,低热流密度时尾流对气泡动力学行为影响微弱,中高热流密度时尾流影响效果显著。尾流区内液体的水平流动促进了原生气泡间相互碰撞、合并过程,垂直加热面的流动则给气泡施加了向上的曳力,从而降低了气泡生长周期和脱离半径。尾流区内过冷液体的冷却作用使气泡内形成负压,液体从微柱结构内被吸入气泡底部,为其长大提供新鲜液体,避免局部干斑。尾流效应与微柱结构相互作用,能有效促进加热面的气泡合并和脱离过程,提高表面换热能力。

关键词：尾流效应池沸腾微重力动力学微柱阵列结构