检索结果-南通市图书馆

Chinese Journal of Integrative Medicine 2024年第3期30卷 213-221页

作者： ZHANG Yue XIao Yan-wei MA Jing-xin WANG ao-xue Department of Dermatology the Second Hospital of Dalian Medical UniversityDalianLiaoning Province116021China Department of Cell Biology Dalian Medical UniversityDalianLiaoning Province116044China

Objective:To investigate the effect and possible mechanism of hydroxysafflor yellow A(HSYA) on human immortalized keratinocyte cell proliferation and ***:HaCaT cells were treated with *** proliferation was detected by the cell counting kit-8 assay,and cell migration was measured using wound healing assay and Transwell migration *** mRNA and protein expression levels of heparin-binding epidermal growth factor(EGF)-like growth factor(HBEGF),EGF receptor(EGFR),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),mammalian target of rapamycin(mTOR),and hypoxia-inducible factor-1α(HIF-1α) were detected by quantitative real-time polymerase chain reaction(qRT-PCR) and Western blot,***_0084443-overexpressing HaCaT cells and empty plasmid HaCaT cells were constructed using the lentiviral stable transfection and treated with *** expression of circ_0084443 was detected by ***:HSYA(800 μmol/L) significantly promoted HaCaT cell proliferation and migration(P0.05).Conclusion:HSYA played an accelerative role in HaCaT cell proliferation and migration,which may be attributable to activating HBEGF/EGFR and PI3K/AKT signaling pathways,and had a particular inhibitory effect on the keratinocyte negative

关键词： hydroxysafflor yellow A circ_0084443 heparin-binding epidermal growth factor-like growth factor/epidermal growth factor receptor phosphatidylinositol 3-kinase/protein kinase B

Strategies for the development and approval of COVID-19 vaccines and therapeutics in the post-pandemic period

在线全文

学校读者我要写书评

暂无评论

Signal Transduction and Targeted Therapy 2024年第1期9卷 19-35页

作者： Danyi ao xuemei He Jian liu Li Xu State Key Laboratory of Biotherapy West China HospitalSichuan University610041 SichuanPeople’s Republic of China

The spread of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in significant casualties and put immense strain on public health systems worldwide,leading to economic recession and social *** response,various prevention and control strategies have been implemented globally,including vaccine and drug development and the promotion of preventive *** these strategies has effectively curbed the transmission of the virus,reduced infection rates,and gradually restored normal social and economic ***,the mutations of SARS-CoV-2 have led to inevitable infections and reinfections,and the number of deaths continues to ***,there is still a need to improve existing prevention and control strategies,mainly focusing on developing novel vaccines and drugs,expediting medical authorization processes,and keeping epidemic *** measures are crucial to combat the Coronavirus disease(COVID-19)pandemic and achieve sustained,long-term prevention,management,and disease ***,we summarized the characteristics of existing COVID-19 vaccines and drugs and suggested potential future directions for their ***,we discussed the COVID-19-related policies implemented over the past years and presented some strategies for the future.

关键词： prevention sustained approval

Rural labor migration and farmers’arrangements of rice production systems in Central China:Insight from the intergenerational division of labor

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第9期23卷 3200-3214页

作者： xue Shen Quanyu Yang Rongjun ao Shengsheng Gong Key Laboratory for Geographical Process Analysis&Simulation of Hubei Province/College of Urban and Environmental Sciences Central China Normal UniversityWuhan 430079China

Rice production is crucial for food security in China,and its relationship with rural labor migration has been studied *** migration in rural China has taken new forms in recent *** has been a discernible trend wherein adult children have started migrating to cities while their elderly parents return to villages to re-engage in on-farm *** phenomenon has notably shaped the intergenerational division of labor(IDL)within ***,it remains to be seen how farmers adjust their rice production systems in response to the *** age of 60 years for employment injury insurance is the eligibility threshold for off-farm employment and is used to obtain a source of exogenous variation in the *** on a representative household survey of 1,752 rice farmers in the Hubei Province of Central China,our fuzzy regression discontinuity analysis reveals that farmers in IDL households are more likely to adopt ratoon rice(RR)than single cropping rice(SR)or double cropping rice(DR).The effect of the IDL varies under different levels of operational scales and specialized agricultural service *** analysis suggests that farmers’arrangements are associated with two potential mechanisms of downward intergenerational *** transfer for urban housing purchases increases RR in IDL households,and time transfer for intergenerational childcare significantly promotes SR in IDL *** study enhances the understanding of the relationship between rural labor migration and rice production in China,providing a reference for adjusting rice production systems to ensure food security.

关键词： labor migration intergenerational division of labor rice production systems fuzzy regression discontinuity Central China

Incombustible solid polymer electrolytes:A critical review and perspective

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第6期93卷 264-281,I0007页

作者： Kai Wu Jin Tan Zhenfang liu Chenguang Bao ao Li Qi liu Baohua Li College of Materials Science and Engineering Hunan UniversityChangsha 413000HunanChina Tsinghua Shenzhen International Graduate School Tsinghua UniversityShenzhen 055GuangdongChina

Since the advent of the solid-state batteries,employing solid polymer electrolytes(SPEs)to replace routine flammable liquid electrolytes is regarded to be one of the most promising solutions in pursing highenergy-density battery *** with superior thermal stability,good processability,and high mechanical modulus obtain increasing ***,SPE-based batteries are not impenetrable due to their decomposition and combustibility under extreme *** believe incorporating appropriate flame-retardant additives/solvents/fragments into SPEs can intrinsically reduce their flammability to solve the battery safety *** this review,the recent research progress of incombustible SPEs,with special emphasis on flame-retardant structural design,is ***,a brief introduction of flame-retardant mechanism,evaluation index for safety of SPEs,and a detailed overview of the latest advances on diverse-types SPEs in various battery systems are *** deep insight into thermal ru naway process,the free-standing incombustible GPEs,and the ratio nal design of pouch cell structures may be the main directions to motivate revolutionary next-generation for safety batteries.

关键词： Non-flammable electrolyte Solid polymer electrolyte High safety electrolyte Solid state electrolyte Solid state battery

Evolution of pore systems in low-maturity oil shales during thermal upgrading--Quantified by dynamic SEM and machine learning

在线全文

学校读者我要写书评

暂无评论

Petroleum Science 2024年第3期21卷 1739-1750页

作者： Jun liu xue Bai Derek Elsworth Key Laboratory of Deep Underground Science and Engineering(Ministry of Education) Institute of New Energy and Low-Carbon TechnologySichuan UniversityChengdu610065SichuanChina International Quantum Academy Shenzhen518048GuangdongChina Shenzhen Institute of Advanced Electronic Materials Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen518055GuangdongChina Department of Energy and Mineral Engineering Pennsylvania State University ParkPA 16802USA

In-situ upgrading by heating is feasible for low-maturity shale oil,where the pore space dynamically *** characterize this response for a heated substrate concurrently imaged by *** systematically follow the evolution of pore quantity,size(length,width and cross-sectional area),orientation,shape(aspect ratio,roundness and solidity)and their anisotropy—interpreted by machine *** indicate that heating generates new pores in both organic matter and inorganic ***,the newly formed pores are smaller than the original pores and thus reduce average lengths and widths of the bedding-parallel pore ***,the average pore lengths and widths are increased in the bedding-perpendicular ***,heating increases the cross-sectional area of pores in low-maturity oil shales,where this growth tendency fluctuates at300℃.In addition,the orientation and shape of the newly-formed heating-induced pores follow the habit of the original pores and follow the initial probability distributions of pore orientation and ***,limited anisotropy is detected in pore direction and shape,indicating similar modes of evolution both bedding-parallel and *** propose a straightforward but robust model to describe evolution of pore system in low-maturity oil shales during heating.

关键词： Low-maturity oil shale Pore elongation Organic matter pyrolysis In-situthermal upgrading Scanning electron microscopy(SEM) Machine learning

Europium-bearing organic framework with excellent X-ray scintillating luminescence

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第2期42卷 251-255,I0001页

作者： Yugang Zhang Lanhua Chen Xia Wang Wei liu Shu'ao Wang State Key Laboratory of Radiation Medicine and Protection School for Radiological and Interdisciplinary Sciences(RAD-X)and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education InstitutionsSoochow UniversitySuzhou215123China School of Environmental and Materials Engineering Yantai UniversityYantai264005China

Two europium-bearing organic frameworks,termed as EuTPO-1 and EuTPO-2(H_(3)TPO=tris(4-carboxylphenyI)-phosphineoxide),are reported in this work.A series of characterizations of EuTPO-1and EuTPO-2,such as X-ray crystallography and photoluminescence spectroscopy,was performed to expatiate their structure and physicochemical *** of them are constructed by dimers of the europium-oxygen subunit of [Eu_(2)O_(16)] and TPO *** from high X-ray stopping attenuation and excellent luminescence efficiency,they emit sufficient luminescence when irradiated with ***,they possess stable light outputs when exposed to high humidities and strong radiation dose,outperforming the commercial scintillator CsI:*** result paves the way for developing new scintillator and enriches the compound of europium-bearing organic framework with X-ray scintillating luminescence.

关键词： Metal-organic frameworks Scintillating material Luminescence efficiency Rare earths

Peeling of Magneto-responsive Beams with Large Deformation Mediated by the Parallel Magnetic Field

在线全文

学校读者我要写书评

暂无评论

Acta Mechanica Solida Sinica 2024年第3期37卷 457-467页

作者： Gongqi Cao Zhangna xue Shiyang liu Yuchen Jin Jianlin liu College of Pipeline and Civil Engineering China University of Petroleum(East China)Qingdao266580China

Elasto-capillarity phenomena are prevalent in various industrial fields such as mechanical engineering,material science,aerospace,soft robotics,and *** this study,two typical peeling processes of slender beams driven by the parallel magnetic field are investigated based on experimental and theoretical *** first is the adhesion of two parallel beams,and the second is the self-folding of a long *** these two cases,the energy variation method on the elastica is used,and then,the governing equations and transversality boundary conditions are *** is shown that the analytical solutions are in excellent agreement with the experimental *** effects of magnetic induction intensity,distance,and surface tension on the deflection curve and peeling length of the elastica are fully *** results are instrumental in accurately regulating elasto-capillarity in structures and provide insights for the engineering design of programmable microstructures on surfaces,microsensors,and bionic robots.

关键词： Magneto-responsive beam Adhesion and peeling Self-folding Elastica Transversality condition

Structural Engineering of Hierarchical Magnetic/Carbon Nanocomposites via In Situ Growth for High-Efficient Electromagnetic Wave Absorption

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第9期16卷 262-278页

作者： Xianyuan liu Jinman Zhou Ying xue Xianyong Lu Key Laboratory of Bio‑Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityBeijing 100191People’s Republic of China

Materials exhibiting high-performance electromagnetic wave absorption have garnered considerable scientific and technological attention,yet encounter significant *** new materials and innovative structural design concepts is crucial for expanding the application field of electromagnetic wave ***,hierarchical structure engineering has emerged as a promising approach to enhance the physical and chemical properties of materials,providing immense potential for creating versatile electromagnetic wave absorption ***,an exceptional multi-dimensional hierarchical structure was meticulously devised,unleashing the full microwave attenuation capabilities through in situ growth,selfreduction,and multi-heterogeneous interface *** hierarchical structure features a three-dimensional carbon framework,where magnetic nanoparticles grow in situ on the carbon skeleton,creating a necklace-like ***,magnetic nanosheets assemble within this *** impedance matching was achieved by precisely adjusting component proportions,and intelligent integration of diverse interfaces bolstered dielectric *** obtain Fe_(3)O_(4)-Fe nanoparticles/carbon nanofibers/Al-Fe_(3)O_(4)-Fe nanosheets composites demonstrated outstanding performance with a minimum reflection loss(RLmin)value of−59.3 dB and an effective absorption bandwidth(RL≤−10 dB)extending up to 5.6 GHz at 2.2 *** notable accomplishments offer fresh insights into the precision design of high-efficient electromagnetic wave absorption materials.

关键词： Electromagnetic wave absorption Hierarchical structure In situ growth Self-reduction

Fast Cross-Platform Binary Code Similarity Detection Framework Based on CFGs Taking Advantage of NLP and Inductive GNN

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2024年第1期33卷 128-138页

作者： Jinxue PENG Yong WANG Jingfeng xue Zhenyan liu School of Computer Science and Technology Beijing Institute of Technology

Cross-platform binary code similarity detection aims at detecting whether two or more pieces of binary code are similar or not. Existing approaches that combine control flow graphs(CFGs)-based function representation and graph convolutional network(GCN)-based similarity analysis are the best-performing ones. Due to a large amount of convolutional computation and the loss of structural information, the use of convolution networks will inevitably bring problems such as high overhead and sometimes inaccuracy. To address these issues, we propose a fast cross-platform binary code similarity detection framework that takes advantage of natural language processing(NLP)and inductive graph neural network(GNN) for basic blocks embedding and function representation respectively by simulating extracting structural features and temporal features. GNN’s node-centric and small batch is a suitable training way for large CFGs, it can greatly reduce computational overhead. Various NLP basic block embedding models and GNNs are evaluated. Experimental results show that the scheme with long short term memory(LSTM)for basic blocks embedding and inductive learning-based Graph SAGE(GAE) for function representation outperforms the state-of-the-art works. In our framework, we can take only 45% overhead. Improve efficiency significantly with a small performance trade-off.

关键词： Training Semantics Process control Binary codes Feature extraction Natural language processing Graph neural networks

同方期刊数据库

Shock Raman spectra and structural transformation of powdered TKX-50 by the plate impact experiments combined with real-time Raman detection

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2024年第1期31卷 158-162页

作者： xue Yang Qijun liu Yundan Gan Lei Yang Zhengtang liu Fusheng liu Bond and Band Engineering Group School of Physical Science and TechnologySouthwest Jiaotong UniversityChengdu 610031People's Republic of China Xi'an Modern Chemistry Research Institute Xi'an 710065People's Republic of China State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi'an 710072People's Republic of China

As an energetic material of great interest,the work capacity of dihydroxylammonium 5,5’-bistetrazole-1,1’-diolate(TKX-50)has been questioned *** some research groups have explored the reasons for the low working ability of TKX-50,the plane impact experiment on powdered TKX-50 is obviously closer to the practical application,and the conclusions based on this are more ***,we performed shock Hugoniot measurements of powdered TKX-50 between 5.65 and 16.29 *** plane impact experiments of powdered TKX-50 were carried out and the shocked Raman spectra were *** Raman spectroscopy analysis,a new peak of powdered TKX-50 was found between19.47 GPa and 24.96 GPa,which may be caused by decomposition/phase transition and was related with the low work capacity.

关键词： Powdered TKX-50 Hugoniot Raman Decomposition Phase transition