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Intra-thyroid esophageal duplication cyst:A case report

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World Journal of Clinical Cases 2024年第13期12卷 2231-2236页

作者： Hong-Guo Lin Ming Liu xue-yang huang Da-Sheng Liu Department of Vascular Thyroid Surgery The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510006Guangdong ProvinceChina

BACKGROUND Esophageal cysts are relatively rare in clinical practice,with most of the literature comprising case *** cysts protruding into the thyroid gland are easily misdiagnosed as thyroid *** such cases have been reported so *** SUMMARY This article reports the case of a 31-year-old adult male diagnosed with thyroid nodules before *** patient underwent left thyroidectomy and *** the surgery,esophageal cysts were identified in the esophageal muscle and thyroid *** pathology results confirmed a nodular goiter combined with esophageal ***,the patient developed a neck infection and underwent another operation and broad-spectrum antibiotic treatment for *** We report the first clinical case of an esophageal cyst located within the thyroid gland that was successfully treated *** cyst located within the thyroid gland cause difficulties in *** the present study,the contents of the esophageal cysts were calcified foci,and a small amount of fluid mixture,which were easily misdiagnosed as thyroid nodules and misled the surgical methods.

关键词： Esophageal cysts Thyroid Diagnosed Surgery Case report

多点激励下多跨斜拉桥缩尺模型的地震响应研究.部分1:振动台试验（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2014年第5期15卷 351-363页

作者： Zhou-hong ZONG Rui ZHOU xue-yang huang Zhang-hua XIA School of Civil Engineering Southeast University State Key Laboratory for Disaster Reduction in Civil Engineering Tongji University School of Civil Engineering Fuzhou University

研究目的：创新要点：为多塔斜拉桥在一致激励和非一致激励下地震响应的研究提供地震模拟振动台全桥试验方法，并有助于加强多塔斜拉桥抗震性能和抗震设计的认识。1．建立了地震模拟振动台多台阵试验方法，并首次将其应用于多塔斜拉桥... 详细信息

研究目的：创新要点：为多塔斜拉桥在一致激励和非一致激励下地震响应的研究提供地震模拟振动台全桥试验方法，并有助于加强多塔斜拉桥抗震性能和抗震设计的认识。1．建立了地震模拟振动台多台阵试验方法，并首次将其应用于多塔斜拉桥全桥比例缩尺模型的地震响应分析之中；2．通过地震模拟振动台试验，揭示了多塔斜拉桥在多点一致激励和多点非一致激励的地震响应特性并提出了多塔斜拉桥在强震下的破坏模式。研究方法：1．基于动力相似理论，设计与制作了多塔斜拉桥的全桥比例缩尺模型（图2）；2．利用地震模拟振动台多台阵试验，根据在不同地震波作用下和考虑行波效应后多塔斜拉桥模型的主梁和主塔响应，分析了多塔斜拉桥在多点一致激励和多点非一致激励的地震响应特性（图5～图8）；3．根据在地震波不同强度作用下多塔斜拉桥模型的主梁和主塔响虚，分析了多塔斜拉桥在强震下的破坏模式和地震响应（图9）。重要结论：1．江心波作用下该多塔斜拉桥的地震响应大于其他三种地震波；2．多塔斜拉桥在抗震设计时需要考虑行波效应的影响；3．在El-Centro波的加速度峰值高达4．0m／s^2时，多塔斜拉桥模型出现了支座破坏。

关键词：多塔斜拉桥地震模拟振动台台阵试验多点激励行波效应破坏模式

多点激励下多跨斜拉桥缩尺模型的地震响应研究.部分2:数值分析（英文）

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2014年第6期15卷 405-418页

作者： Rui ZHOU Zhou-hong ZONG xue-yang huang Zhang-hua XIA State Key Lab for Disaster Reduction in Civil Engineering Tongji University School of Civil Engineering Southeast University School of Civil Engineering Fuzhou University

研究目的:通过非线性动力有限元分析,模拟多塔斜拉桥在多点激励下的地震响应以及揭示其在强震下的倒塌破坏模式。创新要点:解决了多塔斜拉桥的非线性动力数值模拟技术,并首次模拟了多塔斜拉桥在强震下的破坏模式。研究方法:首先采用隐式... 详细信息

研究目的:通过非线性动力有限元分析,模拟多塔斜拉桥在多点激励下的地震响应以及揭示其在强震下的倒塌破坏模式。创新要点:解决了多塔斜拉桥的非线性动力数值模拟技术,并首次模拟了多塔斜拉桥在强震下的破坏模式。研究方法:首先采用隐式的Newmark-β法求解多点地震激励下的非线性动力方程(图3),随后采用显式的中心差分格式对强震作用下桥梁的倒塌破坏过程进行数值仿真(图4)。重要结论:1.单主梁模型的数值结果可以很好地反映地震模拟振动台试验的地震响应结果;2.在加速度峰值为4.0 m/s2的El-Centro波时,多塔斜拉桥模型只出现了中塔支座的破坏;3.在加速度峰值为4.0 m/s2的江心波时,多塔斜拉桥模型先后出现了支座破坏、拉索与塔的连接破坏以及中塔上塔柱段的单元失效。

关键词：多塔斜拉桥非线性有限元分析多点激励破坏模式

Rapid rehabilitation technique with integrated traditional Chinese and Western medicine promotes postoperative gastrointestinal function recovery

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World Journal of Gastroenterology 2020年第23期26卷 3271-3282页

作者： Li-Xing Cao Zhi-Qiang Chen Zhi Jiang Qi-Cheng Chen Xiao-Hua Fan Shi-Jun Xia Jin-Xuan Lin Hua-Chan Gan Tao Wang yang-xue huang Perioperative Research Team The Second Affiliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong ProvinceChina The Second Clinical College of Guangzhou University of Chinese Medicine Guangzhou University of Chinese MedicineGuangzhou 510000Guangdong provinceChina

BACKGROUND During the perioperative period, the characteristic therapy of traditional Chinese medicine is effective in improving postoperative rehabilitation. In large-scale hospitals practicing traditional Chinese medicine, there is accumulating experience related to the promotion of fast recovery in the perioperative *** To evaluate the efficacy and safety of Yikou-Sizi powder hot compress on Shenque acupuncture point combined with rapid rehabilitation *** This prospective, multicenter, randomized, controlled study included two groups: Treatment group and control group. The patients in the treatment group and control group received Yikou-Sizi powder hot compress on Shenque acupuncture point combined with rapid rehabilitation technique and routine treatment, respectively. Clinical observation regarding postoperative recovery of gastrointestinal function was performed, including the times to first passage of flatus, first defecation, and first normal bowel sounds. The comparison between groups was conducted through descriptive analysis, χ~2, t, F, and rank-sum *** There was a statistically significant difference in the time to postoperative first defecation between the treatment and control group(87.16 ± 32.09 vs 109.79 ±40.25 h, respectively;P 0.05). The hospitalization expenses for the two groups of patients were 62283.45 ±12413.90 and 62059.42 ± 11350.51 yuan, respectively. Although the cost of hospitalization was decreased in the control group, the difference was not statistically significant(P > 0.05). This clinical trial was safe without reports of any

关键词： Rapid rehabilitation technique Traditional Chinese Medicine Western Medicine Colorectal cancer Postoperative gastrointestinal function

Impact of smoking status and pathologic type on epidermal growth factor receptor mutations in lung cancer

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Chinese Medical Journal 2011年第16期124卷 2457-2460页

作者： huang Yi-sheng yang Jin-ji ZHANG Xu-chao yang xue-ning huang Yu-juan XU Chong-rui ZHOU Qing WANG Zhen SU Jian WU Yi-long Guangdong Lung Cancer Institute Guangdong General Hospital &Guangdong Academy of Medical Sciences GuangzhouGuangdong 510080 China

Background Epidermal growth factor receptor （EGFR） responsive to the treatment with tyrosine kinase inhibitors. large series of lung carcinomas. mutations in lung carcinomas can make the disease more We aimed to evaluate the prevalence of EGFR mutations in a Methods We examined 1195 consecutive lung cancer patients for EGFR mutations in exons 18, 19, and 21 using direct sequencing of polymerase chain reaction products. A detailed smoking history was obtained. Patients were categorized as never smokers （〈100 lifetime cigarettes）, former smokers （quit 〉1 year ago）, or current smokers （quit 〈1 year ago）. Results There were EGFR mutations in 9 （4.5%） of 201 squamous carcinomas, in 1 （2%） of 50 large cell carcinomas, and in 1 （2.3%） of 44 small cell carcinomas that were investigated. Three hundred and twenty-seven mutations were found in the series of 858 adenocarcinomas （38.1%）. Among 858 lung adenocarcinomas, we detected EGFR mutations in 250 （48.6%） of 514 never smokers, 39 （33.9%） of 115 former smokers, and 38 （16.6%） of 229 current smokers. Significantly fewer EGFR mutations were found in people who smoked for more than 15 pack-years （P=-0.0002） or stopped smoking less than 15 years ago （P=0.033） compared with individuals who never smoked. Conclusions Adenocarcinoma is the most frequent EGFR mutation pathologic type in lung cancer. The likelihood of EGFR mutations in exons 18, 19 and 21 decreases as the number of pack-years increases. Mutations were less common in people who smoked for more than 15 pack-years or who stopped smoking cigarettes less than 15 years ago. These data can assist clinicians in assessing the likelihood of exons 18, 19, or 21 EGFR mutations in Chinese patients with lung cancer when mutational analysis is not feasible.

关键词： lung neoplasms smoking pathologic type receptor, epidermal growth factor mutation

High-temperature-tolerant flexible supercapacitors: Gel polymer electrolytes and electrode materials

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Journal of Energy Chemistry 2025年第1期100卷 426-457页

作者： Chong Peng Xinyi huang Mingwei Zhao Shuling Liao Quanhong yang Nianjun yang Siyu Yu School of Chemistry & Chemical Engineering Southwest University Nanoyang Group Tianjin Key Laboratory of Advanced Carbon and Electrochemical Energy Storage School of Chemical Engineering and Technology and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin University Department of Chemistry & IMO-IMOMEC Hasselt University

The development of flexible supercapacitors(FSCs) capable of operating at high temperatures is crucial for expanding the application areas and operating conditions of supercapacitors. Gel polymer electrolytes and electrode materials stand as two key components that significantly impact the efficacy of hightemperature-tolerant FSCs(HT-FSCs). They should not only exhibit high electrochemical performance and excellent flexibility, but also withstand intense thermal stress. Considerable efforts have been devoted to enhancing their thermal stability while maintaining high electrochemical and mechanical performance. In this review, the fundamentals of HT-FSCs are outlined. A comprehensive overview of state-of-the-art progress and achievements in HT-FSCs, with a focus on thermally stable gel polymer electrolytes and electrode materials is provided. Finally, challenges and future perspectives regarding HT-FSCs are discussed, alongside strategies for elevating operational temperatures and *** review offers both theoretical foundations and practical guidelines for designing and manufacturing HT-FSCs, further promoting their widespread adoption across diverse fields.

关键词： Flexible supercapacitors High-temperature tolerance Gel polymer electrolytes Electrode materials

Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO2 and HCHO driven by photoelectrocatalysis

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Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang yang Jianfeng Zheng Guoyu Wang Yifei Gao Yatao yang Jia Li Xiaojin Han Yan Cui Zhanggen huang National Key Laboratory of High Efficiency and Low Carbon Utilization of Coal Institute of Coal Chemistry Chinese Academy of Science University of Chinese Academy of Science Shenyang University of Chemical Technology

Photoelectrocatalytic coupling CO2and volatile organic compounds （VOCs） is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO2and the competitive hydrogen evolution of ***,a modified g-C3N4/ZnAl-LDH Z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol *** revealed by in-situ characterizations and density functional theory calculations,CO2and HCHO were absorbed at Zn site and N site,***,*CO generated from CO2and HCHO was converted to*CH3O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH3O in electrocatalysis *** from the“*CO+*CH3O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO2and HCHO simultaneously driven by light and electricity.

关键词： Photoelectrocatalysis Z-scheme C–C coupling Ethanol

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin yang Yu-Wen Alvin huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

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混合时间窗约束下多式联运最优路径选择研究

铁道运输与经济 2018年第8期40卷 6-11页

作者：吕学伟杨斌黄振东上海海事大学物流科学与工程研究院上海201306

在实际运输过程中,混合时间窗对多式联运最优运输方案的选择具有重要影响。为更加科学合理地规划多式联运网络路径和选择运输方式,以混合时间窗为约束条件,以总成本最小为目标,建立多式联运最优路径选择模型,运用蚁群算法求解相关算例,... 详细信息

在实际运输过程中,混合时间窗对多式联运最优运输方案的选择具有重要影响。为更加科学合理地规划多式联运网络路径和选择运输方式,以混合时间窗为约束条件,以总成本最小为目标,建立多式联运最优路径选择模型,运用蚁群算法求解相关算例,并将结果与无混合时间窗约束下的优化结果进行对比分析。结果表明,无论是总费用、总时间,还是单个费用、单个时间,有混合时间窗约束的数值均高于或等于无时间窗约束的数值,因而在实际确定多式联运运输方案时应充分考虑混合时间窗的影响。

关键词：多式联运集装箱运输混合时间窗最优路径约束条件蚁群算法