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The regulatory mechanism of rapid lignification for timely anther dehiscence

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Journal of Integrative Plant Biology 2024年第8期66卷 1788-1800页

作者： Jing-Shi xue Yi-Feng Feng Ming-Qi zhang qin-Lin Xu Ya-Min Xu Jun-qin Shi Li-Fang Liu Xiao-Feng Wu Shui Wang Zhong-Nan Yang Shanghai Key Laboratory of Plant Molecular Sciences College of Life SciencesShanghai Normal UniversityShanghai 200234China National Key Laboratory of Plant Molecular Genetics CAS Center for Excellence in Molecular Plant SciencesInstitute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200032China University of the Chinese Academy of Sciences Beijing 100049China Development Center of Plant Germplasm Resources College of Life SciencesShanghai Normal UniversityShanghai 200234China

Anther dehiscence is a crucial event in plant reproduction,tightly regulated and dependent on the lignification of the anther *** this study,we investigated the rapid lignification process that ensures timely anther dehiscence in *** findings reveal that endothecium lignification can be divided into two distinct *** Phase Ⅰ,lignin precursors are synthesized without polymerization,while Phase Ⅱ involves simultaneous synthesis of lignin precursors and *** transcription factors MYB26,NST1/2,and ARF17 specifically regulate the pathway responsible for the synthesis and polymerization of lignin monomers in Phase Ⅱ.MYB26-NST1/2 is the key regulatory pathway responsible for endothecium lignification,while ARF17 facilitates this process by interacting with ***,our results demonstrate that the lignification of the endothecium,which occurs within approximately 26 h,is much faster than that of the vascular *** findings provide valuable insights into the regulation mechanism of rapid lignification in the endothecium,which enables timely anther dehiscence and successful pollen release during plant reproduction.

关键词： anther dehiscence ARF17 endothecium lignin MYB26 NST

Synergically regulated silver species and surface oxygen on manganese oxide for promoted activity of formaldehyde oxidation

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Journal of Environmental Sciences 2024年第4期138卷 709-718页

作者： Shuo Hu Jianghao zhang xueyan Chen Xiaoxiao qin Jinshui Yao Changbin zhang School of Materials Science&Engineering Qilu University of Technology(Shandong Academy of Sciences)Jinan 250353China State Key Joint Laboratory of Environment Simulation and Pollution Control Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China University of Chinese Academy of Sciences Beijing 100049China

Formaldehyde(HCHO)is a common indoor pollutant that is detrimental to human *** efficient removal has become an urgent demand to reduce the public health *** this work,Ag-MnO_(x)-based catalysts were prepared and activated under different atmosphere(i.e.,air,hydrogen(H_(2))and carbon monoxide(CO))for efficient oxidation of *** catalyst activated with CO(Ag/Mn-CO)displayed the highest activity among the tested samples with 90% conversion at 100℃ under a gas space velocity of 75,000 mL/(g_(cat)·hr).Complementary characterizations demonstrate that CO reduction treatment resulted in synergically regulated content of surface oxygen on support to adsorb/activate HCHO and size of Ag particle to dissociate oxygen to oxidize the adsorbed *** contrast,other catalysts lack for either abundant surface oxygen species or metallic silver with the appropriate particle size,so that the integrate activity is limited by one specific reaction *** study contributes to elucidating the mechanisms regulating the oxidation activity of Ag-based catalysts.

关键词： HCHO oxidation Ag-MnO_(x)-based catalyst Activation condition Synergic regulation Surface oxygen Oxidized Ag

Fracture mechanism of inclusions in thick plate center under tensile loading

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Journal of Iron and Steel Research International 2024年第5期31卷 1196-1209页

作者： Lei Hu Li-qin zhang Feng Hu Guo-hong zhang Kuan Zheng Collaborative Innovation Center for Advanced Steels Wuhan University of Science and TechnologyWuhan430081HubeiChina Department of Applied Physics Wuhan University of Science and TechnologyWuhan430081HubeiChina Analysis and Testing Center Wuhan University of Science and TechnologyWuhan430081HubeiChina

Segregation of solute atoms in the center of thick plates of the tempered steel can cause an inhomogeneous structural transformation and generate micron-sized inclusions,which leads to lamellar tearing of thick plate and decreases the plasticity and *** formation and fragmentation mechanisms of micron-sized inclusions,like MnS and(Nb,Ti)C,in the center of thick plates were investigated by using thermodynamic calculations,finite element simulations,and electron backscatter diffraction characterization *** results show that micron-sized inclusions nucleate and grow in the liquid phase,and under tensile loading,they exhibit three fragmentation *** local stress during the fragmentation of inclusions is lower than the critical fracture stress of adjacent grains,and phase boundaries can effectively impede crack propagation into the *** existence of a low proportion of high-angle grain boundaries(58.1%)and high Kernel average misorientation value(0.534°)in the segregation band promotes inclusions fragmentation and crack *** difference in crack initiation and propagation direction caused by the morphology of inclusions and physical properties,as well as different matrix arrest abilities,is the main reasons for the diversity of inclusion fragmentation.

关键词： Thick plate Inclusion Finite element simulation Critical fracture stress Fracture mechanism

A review on plasmonic enhancement of activity and selectivity in electrocatalytic CO_(2)reduction

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Frontiers in Energy 2024年第4期18卷 399-417页

作者： Jing xue Zhenlin CHEN Yuchao zhang Jincai ZHAO Key Laboratory of Photochemistry Beijing National Laboratory for Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

Utilizing plasmonic effects to assist electrochemical reactions exhibits a huge potential in tuning the reaction activities and product selectivity,which is most appealing especially in chemical reactions with multiple products,such as CO_(2)reduction reaction(CO_(2)RR).However,a comprehensive review of the development and the underlying mechanisms in plasmon-assisted electrocatalytic CO_(2)RR remains few and far ***,the fundamentals of localized surface plasmonic resonance(LSPR)excitation and the properties of typical plasmonic metals(including Au,Ag,and Cu)are ***,the potential mechanisms of plasmonic effects(such as hot carrier effects and photothermal effects)on the reaction performance in the field of plasmon-assisted electrocatalytic CO_(2)RR are summarized,which provides directions for the future development of this *** is concluded that plasmonic catalysts exhibit potential capabilities in enhancing CO_(2)RR while more in situ techniques are essential to further clarify the inner mechanisms.

关键词： localized surface plasmonic resonance(LSPR)effect plasmonic metals CO_(2)reduction reaction(CO_(2)RR) hot carrier effect photothermal effect

Full waveform inversion based on hybrid gradient

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Petroleum Science 2024年第3期21卷 1660-1670页

作者： Chuang Xie Zhi-Liang qin Jian-Hua Wang Peng Song Heng-Guang Shen Sheng-Qi Yu Ben-Jun Ma xue-qin Liu qingdao Innovation and Development Base Harbin Engineering UniversityQingdao266000ShandongChina qingdao Innovation and Development Center Harbin Engineering UniversityQingdao266000ShandongChina CNOOC Research Institute Co. Ltd.Beijing100028China College of Marine Geoscience Ocean University of ChinaQingdao266100ShandongChina Weihai Sunfull Geophysical Exploration Equipment Co. Ltd.Weihai264209ShandongChina

The low-wavenumber components in the gradient of full waveform inversion(FWI)play a vital role in the stability of the ***,when FWI is implemented in some high frequencies and current models are not far away from the real velocity model,an excessive number of low-wavenumber components in the gradient will also reduce the convergence rate and inversion *** solve this problem,this paper firstly derives a formula of scattering angle weighted gradient in FWI,then proposes a hybrid *** hybrid gradient combines the conventional gradient of FWI with the scattering angle weighted gradient in each inversion frequency band based on an empirical formula derived *** weighted hybrid mode,we can retain some low-wavenumber components in the initial lowfrequency inversion to ensure the stability of the inversion,and use more high-wavenumber components in the high-frequency inversion to improve the convergence *** results of synthetic data experiment demonstrate that compared to the conventional FWI,the FWI based on the proposed hybrid gradient can effectively reduce the low-wavenumber components in the gradient under the premise of ensuring inversion *** also greatly enhances the convergence rate and inversion accuracy,especially in the deep part of the *** the field marine seismic data experiment also illustrates that the FWI based on hybrid gradient(HGFWI)has good stability and adaptability.

关键词： Full waveform inversion Hybrid gradient Scattering angle weighted Low-wavenumber component

Improving strength-ductility synchronously of Electron beam welded Ti600/Ti2AlNb joint through isothermal forging

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Progress in Natural Science:Materials International 2024年第3期34卷 532-539页

作者： Yongqiang zhang Xiangyi xue Guoming Zheng Jingli zhang Huiming Li Shewei Xin State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi'an qin Ti Intelligent Manufacturing Technologies Co.Ltd. Northwest Institute for Nonferrous Metal Research Xi'an University of Science and Technology Avic Xi'an Aircraft Industry Group Company Ltd.

Different alloys can be flexibly combined to meet the performance needs of different parts of the compressor disc by welding process. However, achieving a good combination of dissimilar alloys with different mechanical properties has always been a research difficulty. In this work, a Ti600/Ti2AlNb joint was fabricated through electron beam welding and an isothermal forging was used to optimized its microstructure and mechanical performance. The isothermal forging process increases the ultimate tensile strength（UST） and yield strength（YS）of the Ti600/Ti2AlNb joint by ～18 %, while ～2.5 times the ductility. It is indicated that before forging, the Ti600/Ti2AlNb joint exhibits a much lower strength than that of Ti600 matrix, whereas the opposite is true after isothermal forging. The isothermal forging broken the coarse columnar grains of Ti600/Ti2AlNb joint and render to an equiaxed B2 structure in which the acicular α2and O phase are precipitated, resulting a synchronous enhancement of strength and ductility. This work may pave an effective routine for improving the comprehensive mechanical properties of dissimilar metal welding joint.

关键词： Electron beam welding Isothermal forging Mechanical performance Ti600/Ti2AlNb joint

Stepping forward:T-cell redirecting bispecific antibodies in cancer therapy

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Acta Pharmaceutica Sinica B 2024年第6期14卷 2361-2377页

作者： Xiaojing qin Wenjing Ning Han Liu xue Liu Wenxin Luo Ningshao Xia State Key Laboratory of Vaccines for Infectious Diseases Xiang An Biomedicine LaboratorySchool of Public HealthXiamen UniversityXiamen 361102China National Institute of Diagnostics and Vaccine Development in Infectious Diseases State Key Laboratory of Molecular Vaccinology and Molecular DiagnosticsNational Innovation Platform for IndustryeEducation Integration in Vaccine Researchthe Research Unit of Frontier Technology of Structural Vaccinology of Chinese Academy of Medical SciencesXiamen UniversityXiamen 361102China

T cell-redirecting bispecific antibodies are specifically designed to bind to tumor-associated antigens,thereby engaging with CD3 on the T cell *** linkage between tumor cells and T cells actively triggers T cell activation and initiates targeted killing of the identified tumor *** antibodies have emerged as one of the most promising avenues within tumor ***,despite success in treating hematological malignancies,significant advancements in solid tumors have yet to be *** this review,we aim to address the critical challenges associated with T cellredirecting bispecific antibodies and explore novel strategies to overcome these obstacles,with the ultimate goal of expanding the application of this therapy to include solid tumors.

关键词： Bispecific antibody(BsAbs) T-cell redirecting BsAbs Tumor-associated antigens Toxicity Cytokine release syndrome Tumor microenvironment Cancer immunotherapy Combination therapy strategies

Natural long-chain saturated fatty acids doped LNPs enabling spleen selective mRNA translation and potent cancer immunotherapy

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Nano Research 2024年第3期17卷 1804-1817页

作者： Fazhan Wang Meng zhang Meiling Tian Jia Lou Longze Pan Xiaoke Gao Lijing zhang Xiaohan Lou Linyu Zhu Yuqiao Sheng Ming Wang Rui xue Wenjing Deng Shuai Shao Zhihai qin Medical Research Center The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhou 450052China Translational Medical Center The First Affiliated Hospital of Zhengzhou UniversityZhengzhou UniversityZhengzhou 450052China Department of Neuro-Intensive Care Unit The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Academy of Medical Sciences Zhengzhou UniversityZhengzhou 450052China

Rationally tailored lipid nanoparticles(LNPs)with efficient and tunable delivery of mRNA in vivo are crucial for mRNA *** expression of antigenic protein in lymphoid tissues/organs could improve the immunostimulatory efficacy and safety of LNPs-based mRNA *** by the metabolic behavior that long-chain saturated fatty acids tending to enter lymphoid tissue rather than the liver,we developed fatty acid-doped LNPs capable of mediating differential protein expressions in the liver and spleen when administered *** the molar ratio of saturated fatty acid located 60%–70%,the doped LNPs achieved the spleen selective mRNA *** mechanism could be attributed to the different cellular uptake behaviors of saturated fatty acids in *** with a model antigen(ovalbumin)mRNA-loaded spleen selective LNPs,we observed enhanced antigen-specific T cell immune responses,and potent immunotherapeutic and immunoprophylactic efficacy in the mouse lymphoma *** natural long-chain saturated fatty acids metabolic characteristics-inspired design of LNPs for spleen-selective mRNA vaccines delivery will provide references for designing mRNA vaccines with high efficacy and safety for tumor immunotherapy.

关键词： mRNA vaccine lipid nanoparticles spleen long-chain saturated fatty acid cancer immunotherapy

Big Data Application Simulation Platform Design for Onboard Distributed Processing of LEO Mega-Constellation Networks

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China Communications 2024年第7期21卷 334-345页

作者： zhang Zhikai Gu Shushi zhang qinyu xue Jiayin School of Electronics and Information Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Guangdong Provincial Key Laboratory of Aerospace Communication and Networking Technology Shenzhen 518055China Broadband Communications Research Department Peng Cheng LaboratoryShenzhen 518000China

Due to the restricted satellite payloads in LEO mega-constellation networks(LMCNs),remote sensing image analysis,online learning and other big data services desirably need onboard distributed processing(OBDP).In existing technologies,the efficiency of big data applications(BDAs)in distributed systems hinges on the stable-state and low-latency links between worker ***,LMCNs with high-dynamic nodes and long-distance links can not provide the above conditions,which makes the performance of OBDP hard to be intuitively *** bridge this gap,a multidimensional simulation platform is indispensable that can simulate the network environment of LMCNs and put BDAs in it for performance *** STK's APIs and parallel computing framework,we achieve real-time simulation for thousands of satellite nodes,which are mapped as application nodes through software defined network(SDN)and container *** elaborate the architecture and mechanism of the simulation platform,and take the Starlink and Hadoop as realistic examples for *** results indicate that LMCNs have dynamic end-to-end latency which fluctuates periodically with the constellation *** to ground data center networks(GDCNs),LMCNs deteriorate the computing and storage job throughput,which can be alleviated by the utilization of erasure codes and data flow scheduling of worker nodes.

关键词： big data application Hadoop LEO mega-constellation multidimensional simulation onboard distributed processing