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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2024年第3期25卷 268-274页

作者： Jjijie ye Xuan XU Chuande WU Department of Chemistry Zhejiang UniversityHangzhou 310058China

Three polyoxometalate-based hybrid coordination materials,[Co_(8)(H_(2)O)_(34)(pz)_(2){Co_(4)(H_(2)O)_(2)P_(4)W_(30)O_(112)}]·16H_(2)O(compound 1),[H_(3)O]_(4)[Co_(6)(H_(2)O)_(22)(pz)_(2){Co_(4)(H_(2)O)_(2)P_(4)W_(30)O_(112)}]·21H_(2)(compound 2),and[H_(3)O]_(4)[Co_(6)(H_(2)O)_(22){Co_(4)(H_(2)O)_(2)P_(4)W_(30)O_(112)}]·29H_(2)O(compound 3)(pz-pyrazine),were built from the linkage of[Co_(4)(H_(2)O)_(2)(P_(2)W_(15)O_(56)_(2)]^(16-)-(abbreviated as{Co_(4)P_(4)W_(30})polyanions and pz and/or cobalt(II)*** compounds 1 and 2 consisted of the same components,their lamellar networks were quite *** inorganic lamellar network in compound 3 was constructed by connecting{Co_(4)P_(4)W_(30)}units with cobalt(I)*** work demonstrates that the coordination modes of{Co_(4)P_(4)W_(30)}are very sensitive to synthesis conditions,while the ring-belt tetrametals are easily substituted by different transition metal cations under mild reaction conditions.

关键词： Cobalt Crystal structure Cyclic voltammetry Hybrid Polyoxometalate

A Review on Vibration Control of Multiple Cylinders Subjected to FlowInduced Vibrations

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China Ocean Engineering 2024年第2期38卷 183-197页

作者： XU Wan-hai MA ye-xuan State Key Laboratory of Hydraulic Engineering Intelligent Construction and Operation Tianjin UniversityTianjin 300350China Institute of Mechanics Chinese Academy of SciencesBeijing 100190China

The fatigue damage caused by flow-induced vibration(FIV)is one of the major concerns for multiple cylindrical structures in many engineering *** FIV suppression is of great importance for the security of many cylindrical *** active and passive control methods have been employed for the vibration suppression of an isolated cylinder undergoing vortex-induced vibrations(VIV).The FIV suppression methods are mainly extended to the multiple cylinders from the vibration control of the isolated *** to the mutual interference between the multiple cylinders,the FIV mechanism is more complex than the VIV mechanism,which makes a great challenge for the FIV *** efforts have been devoted to vibration suppression of multiple cylinder systems undergoing FIV over the past two *** control methods,such as helical strakes,splitter plates,control rods and flexible sheets,are not always effective,depending on many influence factors,such as the spacing ratio,the arrangement geometrical shape,the flow velocity and the parameters of the vibration control *** FIV response,hydrodynamic features and wake patterns of the multiple cylinders equipped with vibration control devices are reviewed and *** FIV suppression efficiency of the vibration control methods are analyzed and compared considering different influence *** research on the FIV suppression of multiple cylinders is suggested to provide insight for the development of FIV control methods and promote engineering applications of FIV control methods.

关键词： flow-induced vibration vibration control multiple cylinders tandem side-by-side staggered

Terahertz sensing with a 3D meta-absorbing chip based on two-photon polymerization printing

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Photonics Research 2024年第5期12卷 895-903页

作者： xueER CHEN LONGFANG ye DAQUAN YU School of Electronic Science and Engineering Xiamen UniversityXiamen 361005China Institute of Electromagnetics and Acoustics Xiamen UniversityXiamen 361005China Xiamen Sky Semiconductor Technology Co. Ltd.Xiamen 361026China

The narrowband meta-absorbers exhibit significantly enhanced electromagnetic confinement capabilities, showcasing broad application prospects in sensing fields. They can be applied for biomarker detection, chemical composition analysis, and monitoring of specific gas in the environment. In this work, we propose a 3D meta-absorber with an out-of-plane plasma mechanism based on a two-photon printing system. Compared to the conventional fabrication of a metal-insulator-metal 2D meta-absorber, the 3D absorber is composed of a metal layer and a resin layer from top to bottom;its manufacturing process is simpler, only including two-photon printing and magnetron sputtering deposition. A noticeable absorbing resonance appears at 0.3142 THz with perfect absorbance with a high Q-factor of 104.67. The theoretical sensitivity to the refractive index of the sensor reaches up to172.5 GHz/RIU, with a figure of merit (FOM) of 19.56. In the experiments, it was validated as a meta-absorber with high sensitivity for doxycycline (DCH). As the DCH concentration increases from 0 to 4 mg/mL, the absorption intensity decreases around 49%, while the resonant frequency shift is around 70 GHz. It reflects the real-time residual content of DCH, and is potentially applied in trace antibiotic detection. The results showcase a perfect narrowband absorption capability with strong electromagnetic confinement in the terahertz spectrum, along with high-Q sensing characteristics of DCH. Compared to 2D metamaterials, the diversity of3D metamaterial significantly expands, and introduces additional effects to provide greater flexibility in manipulating electromagnetic waves. The 3D device offers opportunities for the application of terahertz biochemical sensing.

关键词： absorber printing absorbing

Finite Element Simulation Analysis of a Novel 3D-FRSPA for Crawling Locomotion

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Computer Modeling in Engineering & Sciences 2024年第5期139卷 1401-1425页

作者： Bingzhu Wang Xiangrui ye College of Mechanics and Materials Hohai UniversityNanjing211100China Department of Fundamental Ma’anshan UniversityMa’anshan243100China

A novel three-dimensional-fiber reinforced soft pneumatic actuator(3D-FRSPA)inspired by crab claw and human hand structure that can bend and deform independently in each segment is *** has an omni-directional bending configuration,and the fibers twined symmetrically on both sides to improve the bending performance of *** this paper,the static and kinematic analysis of 3D-FRSPA are carried out in *** effects of fiber,pneumatic chamber and segment length,and circular air chamber radius of 3D-FRSPA on the mechanical performance of the actuator are discussed,*** soft mobile robot composed of 3D-FRSPA has the ability to ***,the crawling processes of the soft mobile robot on different road conditions are studied,respectively,and the motion mechanism of the mobile actuator is *** numerical results show that the soft mobile robots have a good comprehensive performance,which verifies the correctness of the *** work shows that the proposed structures have great potential in complex road conditions,unknown space detection and other operations.

关键词： 3D-FRSPA bionic structure theoretical modeling crawling application obstacle avoidance analysis numerical investigation

Acupoint catgut-embedding therapy ameliorates DNCB-induced atopic dermatitis in BALB/c mice by regulating Th2 type immune response and reducing infiltration of CD4^(+)and CD8^(+)cells

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Traditional Medicine Research 2024年第9期9卷 14-20页

作者： Cheng Qin Xiang-Yi Kong Fang Wang Jin Xu Zhuo Zhang xue-Song Yang Jian-Zhou ye College of First Clinical Medicine Yunnan University of Traditional Chinese MedicineKunming 650500China Yunnan Key Laboratory of Dai and Yi Medicines Yunnan University of Chinese MedicineKunming 650500China Yunnan Provincial Key Laboratory of Molecular Biology for Sinomedicine Yunnan University of Chinese MedicineKunming 650500China Department of Dermatology The First Affiliated Hospital of Yunnan University of Traditional Chinese MedicineKunming 650021China

Background:This study aimed to assess how acupoint catgut-embedding therapy influences Th2-type immune response and the infiltration of CD4^(+)and CD8^(+)cells in DNCB-induced atopic dermatitis in BALB/c *** also conducted an initial examination of the underlying molecular ***:Seventy-two mice were randomly divided into four groups:normal control,DNCB-induced atopic dermatitis model(AD),AD with acupoint catgut-embedding treatment(ADA),and AD with sham-acupoint catgut-embedding *** DNCB challenge to induce AD,the ADA group received acupoint catgut-embedding therapy treatment at Zusanli(ST 36)and Quchi(LI 11)acupoints every other week from day *** in the AD with sham-acupoint catgut-embedding treatment group underwent the same procedure as the ADA group but without catgut *** was assessed using SCORAD on treatment days 1,10,and *** day 18,nine mice per group were euthanized,and the remaining on day *** changes were observed using hematoxylin-eosin and immunohistochemistry ***-α,IL-4,IL-6,and IL-13 levels were analyzed by ELISA,and GATA3 and STAT6 protein levels by western ***:After 20 days of acupoint catgut-embedding therapy treatment,mice showed reduced dermatitis scores compared to DNCB-induced AD-like *** decreases occurred in serum IL-4,IL-6,IL-13,and TNF-α*** analysis revealed marked reductions in CD4^(+)and CD8^(+)cell infiltration,as well as GATA3 and STAT6 protein ***:Acupoint catgut-embedding therapy may effectively alleviate atopic dermatitis by suppressing Th2 immune responses via the STAT6-GATA3 pathway and reducing CD4^(+)and CD8^(+)T cell infiltration in skin lesions.

关键词： atopic dermatitis acupoint catgut-embedding therapy Th2 type immune response

Commentary:Mammokine directs beige adipocytes to reserve energy for milk production in breast

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Acta Pharmaceutica Sinica B 2024年第3期14卷 1472-1476页

作者： Lina Tang Jianping ye Metabolic Disease Research Center Zhengzhou University Affiliated Zhengzhou Central HospitalZhengzhou 450007China Research Center for Basic Medicine Academy of Medical SciencesZhengzhou UniversityZhengzhou 450052China

Beige/brown adipocytes play a crucial role in regulating the body’s overall energy *** thermogenic function is under the influence of various tissues,including the brain,muscles,and ***,the breast tissue is not in th... 详细信息

关键词： Beige Breast Epitheliail cells scRNA-seq Thermogenesis

Distributed Optimal Formation Control for Unmanned Surface Vessels by a Regularized Game-Based Approach

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IEEE/CAA Journal of Automatica Sinica 2024年第1期11卷 276-278页

作者： Jun Shi Maojiao ye the School of Automation Nanjing University of Science and TechnologyNanjing 210094China IEEE

Dear Editor,This letter explores optimal formation control for a network of unmanned surface vessels(USVs).By designing an individual objective function for each USV,the optimal formation problem is transformed into a noncooperative *** this game theoretic framework,the optimal formation is achieved by seeking the Nash equilibrium of the regularized game.A modular structure consisting of a distributed Nash equilibrium seeker and a regulator is proposed.

关键词： Regular seeking optimal

Building the toolbox for in vivo glia-to-neuron reprogramming

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Neural Regeneration Research 2024年第6期19卷 1171-1172页

作者： ye Xie Bo Chen Departments of Ophthalmology and Neuroscience Icahn School of Medicine at Mount Sinai

Unlike regenerative-competent species that possess a remarkable intrinsic capacity to replenish lost neurons and restore neurocircuits spontaneously, the central nervous system in adult mammals lacks the ability to compensate for the neuronal loss caused by neurodegenerative diseases or traumatic injuries resulting in permanent loss of functionality. Inspired by earlier discoveries that radial glia or astrocytes isolated from the postnatal cortex can generate neurons,

关键词： CONVERSION DISEASE

Phonon-blockade-based multiple-photon bundle emission in a quadratically coupled optomechanical system

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Frontiers of physics 2024年第3期19卷 207-215页

作者： ye-Jun Xu Hong Xie Interdisciplinary Research Center of Quantum and Photoelectric Information Chizhou UniversityChizhou 247000China Department of Mathematics and Physics Fujian Jiangxia UniversityFuzhou 350108China

We propose a scheme to realize antibunched multiple-photon bundles based on phonon blockade in a quadratically coupled optomechanical *** adjusting the detunings to match the conditions of phonon blockade in the photon sidebands,we establish super-Rabi oscillation between zero-photon state and multiple-photon states with adjustable super-Rabi frequencies under appropriate single-phonon resonant *** the system dissipation into account,we numerically calculate the standard and generalized second-order functions of the cavity mode as well as the quantum trajectories of the state populations with Monte Carlo simulation to confirm that the emitted photons form antibunched multiple-photon ***,the desirable n-photon states are reconstructed after a direct phonon emission based on phonon blockade,and thus the single-phonon emission heralds the cascade emission of n-photon *** proposal shows that the optomechanical system can simultaneously behave as antibunched multiple-photon emitter and single-phonon *** a nonclassical source could have potential applications in quantum information science.

关键词： multiple-photon bundle emission phonon blockade optomechanical system

The complex roles of m^(6)A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases

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Neural Regeneration Research 2025年第6期20卷 1582-1598页

作者： Yanxi Li Jing xue Yuejia Ma Ke ye xue Zhao Fangliang Ge Feifei Zheng Lulu Liu Xu Gao Dayong Wang Qing Xia Department of Biochemistry and Molecular Biology College of Basic Medical SciencesHarbin Medical UniversityHarbinHeilongjiang ProvinceChina College of Basic Medical Sciences Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Basic Medical Institute Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Key Laboratory of Heilongjiang Province for Genetically Modified Animals Harbin Medical UniversityHarbinHeilongjiang ProvinceChina Translational Medicine Research and Cooperation Center of Northern China Heilongjiang Academy of Medical SciencesHarbinHeilongjiang ProvinceChina Dongzhimen Hospital Beijing University of Chinese MedicineBeijingChina

N6-methyladenosine(m^(6)A), the most prevalent and conserved RNA modification in eukaryotic cells, profoundly influences virtually all aspects of mRNA metabolism. mRNA plays crucial roles in neural stem cell genesis and neural regeneration, where it is highly concentrated and actively involved in these processes. Changes in m^(6)A modification levels and the expression levels of related enzymatic proteins can lead to neurological dysfunction and contribute to the development of neurological diseases. Furthermore, the proliferation and differentiation of neural stem cells, as well as nerve regeneration, are intimately linked to memory function and neurodegenerative diseases. This paper presents a comprehensive review of the roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, as well as its implications in memory and neurodegenerative diseases. m^(6)A has demonstrated divergent effects on the proliferation and differentiation of neural stem cells. These observed contradictions may arise from the time-specific nature of m^(6)A and its differential impact on neural stem cells across various stages of development. Similarly, the diverse effects of m^(6)A on distinct types of memory could be attributed to the involvement of specific brain regions in memory formation and recall. Inconsistencies in m^(6)A levels across different models of neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease, suggest that these disparities are linked to variations in the affected brain regions. Notably, the opposing changes in m^(6)A levels observed in Parkinson's disease models exposed to manganese compared to normal Parkinson's disease models further underscore the complexity of m^(6)A's role in neurodegenerative processes. The roles of m^(6)A in neural stem cell proliferation, differentiation, and self-renewal, and its implications in memory and neurodegenerative diseases, appear contradictory. These inconsistencies may be a

关键词： Alzheimer's disease cell self-renewal central nervous system memory microglia nerve regeneration neurodegenerative diseases neurogenesis RNA methylation