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Single transmembrane GPCR modulating proteins:neither single nor simple

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Protein & Cell 2024年第6期15卷 395-402页

作者： Meng Wang Jianjun Lyu chao zhang Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Hubei Topgene Research Institute of Hubei Topgene Biotechnology Co. LtdEast Lake High-Tech Development ZoneWuhan 430205China Fundamental Research Center Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center)Tongji UniversityShanghai 200092China

The discovery of G-protein coupled receptor(GPCR)accessory proteins has fundamentally redefined the pharmacological concept of GPCR signaling,demonstrating a more complex molecular basis for receptor specificity on the plasma membrane and impressionable downstream intracellular *** accessory proteins not only contribute to the proper folding and trafficking of receptors but also exhibit selectable receptor preferences.

关键词： specificity GPCR neither

Gate regulated near-infrared photodetector utilizing interlayer excitons for MoS2/CrPS4 heterojunction

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Science China(Information Sciences) 2024年第3期67卷 315-316页

作者： Guoliang xu chao HE Donghong SHI Danmin LIU Wenjie DENG Jingzhen LI Xingtao AN Yongzhe zhang Hebei Provincial Key Laboratory of Photoelectric Control on Surface and Interface College of ScienceHebei University of Science and Technology Key Laboratory of Advanced Functional Materials Ministry of EducationFaculty of Materials and ManufacturingBeijing University of Technology Key Laboratory of Optoelectronics Technology Ministry of EducationFaculty of Information TechnologyBeijing University of Technology

Excitons play an important role as interconnect in the optical and optoelectronic response and have attracted much attention for understanding the physical matters behind excitons [1, 2]. Excitons in atomically thin transition metal dichalcogenides semiconductors(TMDs) often trap an electron(X-) or a hole(X+) to form so-called trions,

关键词： Excitons

A Review on Flow Boiling of the Fluid with Lower Boiling Point in Micro-Channels

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Journal of Thermal Science 2024年第1期33卷 1-17页

作者： zhang Zhiqiang JIA Li DANG chao Beijing Key Laboratory of Flow and Heat Transfer of Phase Changing in Micro and Small Scale School of MechanicalElectronic and Control EngineeringBeijing Jiaotong UniversityBeijing 100044China

With the advancement of micro machining technology,the high-heat-flux removal from miniature electronic devices and components has become an attractive *** boiling in micro-channels is an optimal form of heat transfer and has been widely employed in high-heat-flux cooling *** comprehensively-reviewed article focused on the available recent literatures of experimental investigation regarding the flow boiling heat transfer and unstable behaviors of the fluid with lower boiling point in *** thermal-fluid characteristics and potential heat transfer mechanisms of low-boiling-point fluids flow boiling in different narrow passages were summarized and *** literatures regarding the pressure drop and occurrence of the unstable phenomena existing in two-phase flow boiling process were also *** emphasis was given to the heat transfer enhancement methods as well as instability elimination,and various methods such as modification of surface and channel flow geometries were *** future researches in the field of micro-scale flow boiling were suggested.

关键词： flow boiling lower boiling point fluids mini/micro-channels instabilities enhancement suppression

Discrete element modeling and parameter calibration of safflower biomechanical properties

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International Journal of Agricultural and Biological Engineering 2024年第2期17卷 37-46页

作者： Zhenguo zhang chao Zeng Zhenyu Xing Peng xu Quanfeng Guo Ruimeng Shi Yunze Wang College of Mechanical and Electrical Engineering Xinjiang Agricultural UniversityUrumqi 830052China Key Laboratory of Xinjiang Intelligent Agricultural Equipment Xinjiang Agricultural UniversityUrumqi 830052China

Understanding the biomechanical properties of safflowers is essential for appropriately designing harvesting machinery and optimizing the harvesting *** is a flexible crop that lacks a basis for relevant simulation parameters,which causes difficulties in designing harvesting *** this study,a calibration method for safflowers was ***,a discrete element model was established by measuring the intrinsic parameters of a safflower,such as its geometric parameters,density,Poisson’s ratio,and modulus of ***,the contact and bonding parameters were calibrated using a combination of physical and simulation *** the contact parameter tests,the Hertz-Mindlin(no-slip)model was implemented for the stacking angle tests conducted regarding the safflower filament.A regular two-level factorial design was used to determine the important factors and perform the steepest climb ***,the Box-Behnken design was adopted to obtain the optimal contact *** the bonding parameter tests,the Hertz-Mindlin model with bonding contact was applied for the safflower shear simulation tests;moreover,the optimum bonding parameters were obtained through the central composite design *** results demonstrated that the relative errors between the simulated and measured stacking angles and maximum shear were 3.19%and 5.29%,*** a result,the safflower simulation parameters were accurately calibrated,providing a reference for appropriately setting the simulation parameters and designing key mechanical components.

关键词： safflower DEM parameter calibration shear test biomechanical properties

Interface structure of α-Mg/14H-LPSO:First-principles prediction and experimental study

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Journal of Rare Earths 2024年第9期42卷 1792-1799,I0006页

作者： Yuan Shi Xiaohua zhang Hongyan Yue chao Li School of Materials Science and Chemical Engineering Harbin University of Science and TechnologyHarbin150040China

The interfacial structure of the α-Mg/14H-LPSO phase in rare earth-including magnesium alloy was investigated via high-angle annular dark-field scanning transmission electron microscopy(HAADFSTEM) imaging and first-principles calculations of density-functional *** possible interfacial models were constructed according to the different terminations of the LPSO phase,and the corresponding interfacial energies were calculated,from which the four most stable structures(Terl-MgY-hollow,Ter2-Zn-hollow,Ter3-MgYII-hollow and Ter4-Mg-bridge) were *** interfacial phase diagrams related to the Y chemical potentials were obtained from the calculations,and the most stable interfacial structure was ***-MgY-hollow and Ter2-Zn-hollow have the lowest interfacial energies in the range of-0.7 eV <Δμγ<-0.6 eV,where fluctuating change of state is the minimized and the interface is the most *** separation work of the two models was calculated to predict the bonding strength of the structures at both ends of the *** calculation results show that the maximum interfacial separation work is 1.45 J/m^(2) for the interface model of α-Mg and 14H-LPSO phase structure with Ter2-Zn-hollow termination.

关键词： Rare earths Magnesium alloy HAADF-STEM LPSO First-principles Interface

Dynamic Scene Graph Generation of Point Clouds with Structural Representation Learning

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Tsinghua Science and Technology 2024年第1期29卷 232-243页

作者： chao Qi Jianqin Yin Zhicheng zhang Jin Tang School of Artificial Intelligence Beijing University of Posts and TelecommunicationsBeijing 100876China Standard and Metrology Research Institute China Academy of Railway Sciences Corporation LimitedBeijing 100081China

Scene graphs of point clouds help to understand object-level relationships in the 3D *** graph generation methods work on 2D structured data,which cannot be used for the 3D unstructured point cloud *** point-cloud-based methods generate the scene graph with an additional graph structure that needs labor-intensive manual *** address these problems,we explore a method to convert the point clouds into structured data and generate graphs without given ***,we cluster points with similar augmented features into groups and establish their relationships,resulting in an initial structural representation of the point ***,we propose a Dynamic Graph Generation Network(DGGN)to judge the semantic labels of targets of different *** dynamically splits and merges point groups,resulting in a scene graph with high *** show that our methods outperform other baseline *** output reliable graphs describing the object-level relationships without additional manual labeled data.

关键词： scene graph generation structural representation point cloud

In-situ coupling construction of interface bridge to enhance electrochemical stability of all solid-state lithium metal batteries

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Journal of Energy Chemistry 2024年第2期89卷 18-26,I0003页

作者： Qianwei zhang Rong Yang chao Li Lei Mao Bohai Wang Meng Luo Yinglin Yan Yiming Zou Lisheng Zhong Yunhua xu International Research Center for Composite and Intelligent Manufacturing Technology Institute of Chemical Power SourcesXi’an University of TechnologyXi’an 710048ShaanxiChina School of Materials Science and Engineering Xi’an University of TechnologyXi’an 710048ShaanxiChina School of Electrical Engineering Xi’an University of TechnologyXi’an 710048ShaanxiChina Yulin University Yulin 719000ShaanxiChina

Polymer-based composite electrolytes composed of three-dimensional Li_(6.4)La_(3)Zr_(2)Al_(0.2)O_(12)(3D-LLZAO)have attracted increasing attention due to their continuous ion conduction and satisfactory mechanical ***,the organic/inorganic interface is incompatible,resulting in slow lithium-ion transport at the ***,the compatibility of organic/inorganic interface is an urgent problem to be *** by the concept of“gecko eaves”,polymer-based composite solid electrolytes with dense interface structures were *** bridging of organic/inorganic interfaces was established by introducing silane coupling agent(3-chloropropyl)trimethoxysilane(CTMS)into the PEO-3D-LLZAO(PL)*** in-situ coupling reaction improves the interface affinity,strengthens the organic/inorganic interaction,reduces the interface resistance,and thus achieves an efficient interface ion transport *** prepared PEO-3D-LLZAO-CTMS(PLC)electrolyte exhibits enhanced ionic conductivity of 6.04×10^(-4)S cm^(-1)and high ion migration number(0.61)at 60℃and broadens the electrochemical window(5.1 V).At the same time,the PLC electrolyte has good thermal stability and high mechanical ***,the Li Fe PO_(4)|PLC|Li battery has excellent rate performance and cycling stability with a capacity decay rate of 2.2%after 100 cycles at 60℃and 0.1 *** advantages of PLC membranes indicate that this design approach is indeed practical,and the in-situ coupling method provides a new approach to address interface compatibility issues.

关键词： Organic/inorganic interphase Coupling effect Composite electrolyte Interface compatibility

Impact response and energy absorption of metallic buffer with entangled wire mesh damper

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Defence Technology（防务技术） 2024年第5期35卷 137-150页

作者： chao Zheng Jun Wu Mangong zhang Xin xue Institute of Metal Rubber&Vibration Noise School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou 350116China Wuhan Second Ship Design and Research Institute Wuhan 430205China

An innovative metallic buffer consisting of series-connected hat-shaped entangled wire mesh damper(EWMD)and parallel springs are proposed in this work to enhance the reliability of engineering *** impact response and the energy dissipation mechanism of hat-shaped EWMD under different quasi-static compression deformations(2-7 mm)and impact heights(100-200 mm)are investigated using experimental and numerical *** results demonstrate distinct stages in the quasi-static mechanical characteristics of hat-shaped EWMD,including stiffness softening,negative stiffness,and stiffness *** loss factor gradually increases with increasing compression deformation before entering the stiffness hardening *** impact loads,the hat-shaped EWMD exhibits optimal impact energy absorption when it enters the negative stiffness stage(150 mm),resulting in the best impact isolation effect of metallic ***,the impact energy absorption significantly decreases when hat-shaped EWMD enters the stiffness hardening ***,quasi-static compression analysis after experiencing different impact loads reveals the disappearance of the negative stiffness ***,with increasing impact loads,the stiffness hardening point progressively shifts to an earlier stage.

关键词： Metallic buffer Hat-shaped EWMD Drop impact Energy absorption characteristics Mechanical behavior

An Improved Thermal Conductivity Measurement Scheme for Macroscopic Graphitic Films Using the Laser Flash Method

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Journal of Thermal Science 2024年第4期33卷 1480-1490页

作者： zhang Peijuan MING Xin LIU Yingjun WANG xuelong SHI Hang HAO Yuanyuan LU Jiahao LIU Zheng LAI Haiwen zhang Ying GAO Weiwei xu Zhen GAO chao MOE Key Laboratory of Macromolecular Synthesis and Functionalization Department of Polymer Science and EngineeringKey Laboratory of Adsorption and Separation Materials&Technologies of Zhejiang ProvinceZhejiang UniversityHangzhou310027China Shanxi-Zheda Institute of Advanced Materials and Chemical Engineering Taiyuan030032China Special Equipment Safety Supervision and Inspection Institute of Jiangsu Province National Graphene Products Quality Inspection and Testing Center(Jiangsu)Wuxi214174China Hangzhou Gaoxi Technol Co. LtdHangzhou311113China China Academy of Aerospace Aerodynamics Beijing100074China

Achieving efficient thermal management urges to exploit high-thermal-conductivity materials to satisfy the boosted demand of heat *** is critical to adopt standardized characterization protocols to evaluate the intrinsic thermal conductivity of thermal management ***,for the most representative laser flash method,the lack of standard measurement methodology and systematic description on the thermal diffusivity and influencing factors has led to significant deviations and confusion of the thermal conduction performance in the emerging thermal management ***,the measurement error factors of thermal diffusivity by the common laser flash analyzer(LFA)are *** high-thermal-conductivity graphitic film(GF)as a typical case,the key factors are analyzed to guide the measurement protocol of related carbon-based thermal management *** basic principle of the LFA measurement,actual pre-processing conditions,instrument parameters setting,and data analysis are elaborated for accurate ***,the graphene thick films and common isotropic materials are also extended to meet various thermal measurement *** on the existing practical problems,we propose a feasible test flow to achieve a unified and standardized thermal conductivity measurement,which is beneficial to the rapid development of carbon-based thermal management materials.

关键词： thermal management graphitic film laser flash method thermal conductivity thermal diffusivity