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Tunable VO_(2) cavity enables multispectral manipulation from visible to microwave frequencies

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Light(Science & Applications) 2024年第3期13卷 510-518页

作者： Hang Wei Jinxin Gu Tao Zhao Zhiyuan Yan He-xiu xu Shuliang Dou Cheng-Wei Qiu Yao Li Center for Composite Materials and Structure Harbin Institute of TechnologyHarbin 150001China National University of Singapore Department of Electrical&Computer EngineeringSingapore 117583Singapore School of Chemical Engineering and Technology Harbin Institute of TechnologyHarbin 150001China Suzhou Laboratory Suzhou 215123China

Optical materials capable of dynamically manipulating electromagnetic waves are an emerging field in memories,optical modulators,and thermal ***,their multispectral design preliminarily attracts much attention,aiming to enhance their efficiency and integration of ***,the multispectral manipulation based on these materials is challenging due to their ubiquitous wavelength dependence restricting their capacity to narrow *** this article,we cascade multiple tunable optical cavities with selective-transparent layers,enabling a universal approach to overcoming wavelength dependence and establishing a multispectral platform with highly integrated *** on it,we demonstrate the multispectral(ranging from 400 nm to 3 cm),fast response speed(0.9 s),and reversible manipulation based on a typical phase change material,vanadium *** platform involves tandem VO_(2)-based Fabry–Pérot(F-P)cavities enabling the customization of optical responses at target bands *** can achieve broadband color-changing capacity in the visible region(a shift of~60 nm in resonant wavelength)and is capable of freely switching between three typical optical models(transmittance,reflectance,and absorptance)in the infrared to microwave regions with drastic amplitude tunability exceeding *** work represents a state-of-art advance in multispectral optics and material science,providing a critical approach for expanding the multispectral manipulation ability of optical systems.

关键词： spectral microwave visible

Nd:YAG water mist laser treatment for giant gestational gingival tumor: A case report

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World Journal of Clinical Cases 2024年第11期12卷 1974-1979页

作者： Hong-Yu Chen Jun-Ji xu xiu-Lin Chang Pei Wu Department of Stomatology Women and Children's Hospital Affiliated to Ningbo UniversityNingbo 315012Zhejiang ProvinceChina

BACKGROUND This case of gestational gingival tumor is huge and extremely rare in clinical *** the growth location of this gingival tumor is in the upper anterior tooth area,it seriously affects the pregnant woman's speech and food,causing great pain to the *** use of Nd:YGA water mist laser to remove the gingival tumor resulted in minimal intraoperative bleeding,minimal adverse reactions,and good postoperative healing,which is worthy of clinical promotion and *** SUMMARY The patient,a pregnant woman,reported a large lump in her mouth on the first day of postpartum *** on medical history and clinical examination,the diagnosis was diagnosed as gestational gingival *** pathological biopsy also confirmed this *** use of Nd:YAG water mist laser to remove the tumor resulted in minimal intraoperative bleeding,clear surgical field of view,short surgical time,and good postoperative *** In comparison to traditional surgery,Nd:YAG water mist laser surgery is minimally invasive,minimizes cell damage,reduces bleeding,ensures a clear field of vision,and virtually eliminates postoperative edema,carbonization,and the risk of cross *** has unique advantages in oral soft tissue surgery for pregnant ***,the clinical application of Nd:YAG water mist laser for the treatment of gestational gingival tumors is an ideal choice.

关键词： Gestational gingival tumor Nd:YAG water mist laser Granulomatous gingival tumor Minimally invasive dentistry Pregnancy related diseases Oral soft tissue surgery Case report

A Degradable Quaternary Ammonium-Based Pesticide Safe for Humans

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CCS Chemistry 2024年第6期6卷 1499-1511页

作者： Wenwen Han Xiao-Qi xu Xiaodong lian Yanji Chu Yapei Wang Key Laboratory of Advanced Light Conversion Materials and Biophotonics Department of ChemistryRenmin University of ChinaBeijing 100872

Reducing the emission of agrochemicals hazardous to the environment and human health is one of the key targets of the UN’s Sustainable Development Goal ***,we report a kind of quaternary ammonium pesticides with an acid-cleavable silaketal linkage on their backbones that enables control of *** pesticides possess outstanding bactericidal and insecticidal properties but become harmless to humans and other organisms after *** on the conditions of use,the hydrolytic process can be controlled over the time range of 10 min to 3 *** laboratory simulations and agricultural field demonstrations confirm that these pesticides can effectively protect crops from bacterial diseases and *** the sametime,single-dose intragastric administration using diisopropylsilyloxy bisquaternary ammonium salt 9(ISBQAS-9)in mice demonstrates its safety for multiple *** to the advantages of controllable degradability,environmental friendliness,and the low financial cost of these pesticides,this welldesigned strategy holds great promise for the generation of environmentally harmless pesticides and the development of green agriculture.

关键词： antimicrobial materials degradable pesticides insecticidal materials quaternary ammonium surfactants stimulus-cleavable chemistry

Decreased AKAP4/PKA signaling pathway in high DFI sperm affects sperm capacitation

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Asian Journal of Andrology 2024年第1期26卷 25-33页

作者： Kun Zhang xiu-Hua xu Jian Wu Ning Wang Gang Li Gui-Min Hao Jin-Feng Cao Hebei Key Laboratory of Infertility and Genetics Department of Reproductive MedicineSecond Hospital of Hebei Medical UniversityShijiazhuang 050000China Department of Reproductive Medicine Affiliated Hospital of Xuzhou Medical UniversityXuzhou 221000China Department of Neurology The 980th Hospital of the People's Liberation Army Joint Logistics Support Force(Bethune International Peace Hospital)Shijiazhuang 050000China.

The sperm DNA fragmentation index(DFI)is a metric used to assess DNA fragmentation within *** in vitro fertilizationembryo transfer(IVF-ET),high sperm DFI can lead to a low fertilization rate,poor embryo development,early miscarriage,etc.A kinase anchoring protein(AKAP)is a scaffold protein that can bind protein kinase A(PKA)to subcellular sites of specific substrates and protects the biophosphorylation *** protein antigen 17(SPA17)can also bind to *** study intends to explore the reason for the decreased fertilization rate observed in high sperm DFI(H-DFI)patients during *** addition,the study investigates the expression of AKAP,protein kinase A regulatory subunit(PKARIl),and SPA17 between H-DFI and low sperm DFI(L-DFI)***17 at the transcriptional level is abnormal,the translational level increases in H-DFI patients,and the expression of AKAP4/PKARIl protein decreases.H,O,has been used to simulate oxidative stress damage to spermatozoa during the formation of sperm *** indicates that H,O,increases the expression of sperm SPA17 protein and suppresses AKAP4/PKARIl protein *** processes inhibit sperm capacitation and reduce acrosomal *** culture data and IVF outcomes have been *** H-DFI group has a lower fertilization ***,the results indicate that the possible causes for the decreased fertilization rate in the H-DFI patients have included loss of sperm AKAP4/PKARIl proteins,blocked sperm capacitation,and reduced occurrence of acrosome reaction.

关键词： AKAP PKA SPA17 sperm capacitation sperm DNA fragmentation index

Degradation of superhydrophobic aluminium overhead line conductor surfaces

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High Voltage 2024年第4期9卷 763-772页

作者： xu Zhang Chorphaka Plaengpraphan Chengxing lian Wenyuan Li Qinghua Han Simon M.Rowland Ian Cotton Qi Li School of Engineering University of WarwickCoventryUK State Key Laboratory of Electrical Insulation and Power Equipment Xi'an Jiaotong UniversityXi'anChina School of Engineering University of ManchesterManchesterUK School of Engineering Imperial College LondonLondonUK Electrical Engineering School Chongqing UniversityChongqingChina

It has been shown that noise emissions from HV overhead line conductors can be reduced under rain conditions by making their surfaces *** working environment makes ensuring the longevity of any treatment a major *** degradation of various superhydrophobic surfaces generated by applying a superhydrophobic coating and patterning microscale channels is assessed under an AC electric field(18 kV/cm)with continuous water *** examining the droplet distribution on the surfaces during the degradation and the surface roughness before and after degra-dation,the authors demonstrate that no water droplets were found on the microscale patterned surface,but droplets were formed on the coated surface after *** surface roughness reduction of the coated surface and microscale patterned surface was 29.8% and 11.3%,respectively,indicating that the microscale patterned surface has better durability than the superhydrophobic coating under the AC electric stress.

关键词： coating roughness surface

RebL1 is required for macronuclear structure stability and gametogenesis in Tetrahymena thermophila

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Marine Life Science & Technology 2024年第2期6卷 183-197页

作者： Huijuan Hao Yinjie lian Chenhui Ren Sitong Yang Min Zhao Tao Bo Jing xu Wei Wang Key Laboratory of Chemical Biology and Molecular Engineering of Ministry of Education Institute of BiotechnologyShanxi UniversityTaiyuan 030006China School of Life Science Shanxi UniversityTaiyuan 030006China Shanxi Key Laboratory of Biotechnology Taiyuan 030006China

Histone modification and nucleosome assembly play important roles in chromatin-related *** chaperones form different complexes and coordinate histone transportation and *** histone chaperone complexes have been identified in different *** ciliate protozoa(ciliates)have various chromatin structures and different nuclear ***,histone chaperone components and functions of different subunits remain unclear in ***-rahymema thermophila contains a transcriptionally active macronucleus(MAC)and a transcriptionally inactive micronu-cleus(MIC)which exhibit multiple replication and various chromatin remodeling progresses during vegetative growth and sexual developmental ***,we found histone chaperone RebL1 not only localized evenly in the transcriptionally active MAC but also dynamically changed in the MIC during vegetative growth and sexual developmental ***1 knockdown inhibited cellular *** macronuclear morphology became bigger in growing *** abnormal macronuclear structure also occurred in the starvation ***,micronuclear meiosis was disturbed during sexual development,leading to a failure to generate new gametic ***1 potentially interacted with various factors involved in histone-modifying complexes and chromatin remodeling complexes in different developmental ***1 knockdown affected expression levels of the genes involved in chromatin organization and *** together,RebL1 plays a vital role in maintaining macronuclear structure stability and gametogenesis in ***.

关键词： Gametogenesis Histone chaperone Macronuclear structure RebL1 Tetrahymena thermophilaIntroduction

Meta-analysis of transarterial chemoembolization combined with cryoablation vs transarterial chemoembolization alone for≥5 cm hepatocellular carcinoma

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2793-2803页

作者： Jie-Fei Cheng Qiu-lian Sun Ling Tang Xin-Jian xu Xiang-Zhong Huang Department of Radiology The Fifth People’s Hospital of TaizhouTaizhou 225300Jiangsu ProvinceChina Department of Radiology The Fifth People’s Hospital of SuzhouSuzhou 215100Jiangsu ProvinceChina Department of Radiology The Fourth People’s Hospital of TaizhouTaizhou 225300Jiangsu ProvinceChina Department of Interventional Radiology Jiangyin People HospitalJiangyin 214400Jiangsu ProvinceChina

BACKGROUND Hepatocellular carcinoma(HCC)ranks sixth globally in cancer incidence and third in mortality ***,over 70% of HCC patients forego the opportunity for curative surgery or liver transplantation due to inadequate physical examinations,poor physical condition,and limited organ availability upon *** guidelines endorse transarterial chemoembolization(TACE)as the frontline treatment for intermediate to advanced-stage ***(CRA)is an emerging local ablative therapy increasingly used in HCC *** studies suggest that combining CRA with TACE offers complementary and synergistic effects,potentially improving long-term survival ***,the superiority of combined TACE+CRA therapy over TACE alone for HCC lesions equal to or exceeding 5 cm requires further *** To compare the efficacy and safety of TACE combined with CRA vs TACE alone in the treatment of HCC with a diameter of≥5 *** PubMed,EMBASE,Cochrane Library,CNKI,Wanfang,and VIP databases were searched to retrieve all relevant studies on TACE and CRA up to July ***-analysis was performed using RevMan 5.3 *** After screening according to the inclusion and exclusion criteria,6 articles were included,including 2 randomized controlled trials and 4 nonrandomized controlled trials,with a total of 575 patients included in the *** results showed that the objective response rate[odds ratio(OR)=2.56,95%confidence interval(CI):1.66-3.96,P<0.0001],disease control rate(OR=3.03,95%CI:1.88-4.89,P<0.00001),1-year survival rate(OR=3.79,95%CI:2.50-5.76,P<0.00001),2-year survival rate(OR=2.34,95%CI:1.43-3.85,P=0.0008),and 3-year survival rate(OR=3.34,95%CI:1.61-6.94,P=0.001)were all superior to those of the control group;the postoperative decrease in alpha-fetoprotein value(OR=295.53,95%CI:250.22-340.85,P<0.0001),the postoperative increase in CD4 value(OR=10.59,95%CI:8.78-12.40,P<0.00001),and the postoperative decrease in

关键词： Hepatic cancer Cryoablation Chemoembolization Transarterial chemoembolization Meta analysis

Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Case Report

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International Journal of Dermatology and Venereology 2019年第2期2卷 109-111页

作者： Bai-He Wang xiu-lian xu Jian-Fang Sun Department of Pathology Hospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China

Introduction Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare cytotoxic T-cell lymphoma that accounts for less than 1% of all peripheral T-cell *** is characterized by multiple subcutaneous nodules or plaques that occur in the extremities,and it has a poor prognosis if accompanied by hemophagocytic *** histopathological findings and immunophenotype of SPTCL are specific and can help to confirm the *** herein report such a rare case involving a woman with a single facial lesion.

关键词： Case Report SPTCL diagnosis

Preclinical testing of immunotoxicity for animal-derived dermal materials

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Medicine in Novel Technology and Devices 2024年第3期23卷 128-135页

作者： Huan lian Yu Liu Han Wang Jianxia xu Qianqian Han Department of Medical Devices National Institutes for Food and Drug ControlBeijingChina

Animal derived materials have been widely used in biomedical products owing to their good biocompatibility and appropriate mechanical *** is crucial to evaluate the immunotoxicity of such materials in preclinical testing to prevent severe immune responses in *** this study,a pipeline of immunotoxicity tests was established to evaluate animal-derived materials before de-cellularization and final *** pipeline contains a serial of animal tests on BALB/c mice and an in vitro quantification test for a-Gal *** is wellrecognized that the interaction between materials and patients profoundly alters immune responses,thus,a comprehensive dataset including body weight,immune organ coefficient,histopathology,peripheral hematology,serum immunoglobulin level,spleen lymphocyte proliferation rate,and their subpopulation was created and analyzed using the SPSS *** results clearly suggested that the de-cellularized materials possessed better biocompatibility,in addition,the a-Gal antigen content was effectively decreased by 96.0%after ***,this study confirmed that this multi-step enzymatic de-cellularization treatment is a potent method to reduce the immunotoxicity of animal-derived ***,the experimental pipeline will likely be transferable to other biomedical materials and products.

关键词： Immunotoxicity Preclinical testing Animal-derived materials De-cellularization