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Thermoelectric properties of p-type (Bi_(0.15)Sb_(0.85))_2Te_3-PbTe graded thermoelectric materials with different barriers

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Journal of University of Science and Technology Beijing 2005年第4期12卷 347-350页

作者： Guiying xu Yanping gao Changchun Ge Weiping Shen Laboratory of Special Ceramics and Powder Metallurgy University of Science and Technology Beijing Beijing 100083 China

The p-type （Bi0.15Sb0.85）2Te3 and PbTe are typical thermoelectric materials used for low and middle temperature range and functional graded materials （FGM） is an inevitable way to widen the working temperature range. Here two segments graded thermoelectric materials （GTM） consisting of （Bi0.15Sb0.85）2Te3, PbTe and different barriers were fabricated by the common hot pressure method. Metals Fe, Mg and Ni were used as barriers between the two segments. The diffusion of different barriers between the barriers and bases were analyzed by electron microprobe analysis （EMA）. The phase and crystal structures were determined by X-ray diffraction analysis （XRD）. The thermoelectric properties were measured at 303 K along the direction parallel to the pressing direction. The results show that the compositional diffusion occurs when there is no barrier at the interface of the two segments, and the diffusion of Pb is most obvious; as the barrier material, the diffusion of metals Fe, Mg and Ni between different bases is not very obvious, and the thermoelectric properties of GTM is much better than that of the original segment.

关键词： thermoelectric parameter graded materials barrier

基于渐进损伤模型的热固性复合材料电阻焊接头强度的尺寸效应研究

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复合材料科学与工程 2024年第2期 45-51页

作者：赵艺赵刚范欣愉闫忠伟葛亚琼徐剑太原科技大学材料科学与工程学院太原030024 中国科学院宁波材料技术与工程研究所宁波315201 大连理工大学化工学院大连116024 沈阳飞机工业(集团)有限公司沈阳110850

研究了拉剪载荷下热固性复合材料电阻焊接头强度的尺寸效应,揭示了不同搭接尺寸对焊接强度和焊接界面渐进损伤行为的影响规律。为了研究焊接界面的渐进损伤行为,引入双线性内聚力单元,进而建立焊接接头的有限元模型,然后通过电阻焊接的... 详细信息

研究了拉剪载荷下热固性复合材料电阻焊接头强度的尺寸效应,揭示了不同搭接尺寸对焊接强度和焊接界面渐进损伤行为的影响规律。为了研究焊接界面的渐进损伤行为,引入双线性内聚力单元,进而建立焊接接头的有限元模型,然后通过电阻焊接的拉剪试验验证了模型的准确性。在此基础上,建立了不同搭接尺寸的数值模型并对其进行研究。研究结果表明,增大搭接长度或者宽度可以提高接头结构的承载能力,但是当搭接长度较长时,在搭接区域边缘易发生翘曲失效,降低了接头单搭接剪切强度,而宽度则对接头的剪切强度影响很小。

关键词：复合材料电阻焊内聚力模型有限元分析

长时间血清饥饿胁迫对猪骨骼肌卫星细胞代谢和自噬的影响

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中国兽医杂志 2024年第2期60卷 32-38页

作者：高娟范博钧吴雅婕王怡杨跃飞鞠辉明扬州大学广陵学院江苏扬州225000 扬州大学兽医学院江苏高校动物重要疫病与人兽共患病防控协同创新中心江苏扬州225009

为了探究长时间、不同程度饥饿胁迫条件对原代猪骨骼肌卫星细胞(SMSCs)代谢和自噬的影响,本试验通过控制SMSCs培养体系中血清浓度以形成不同程度饥饿胁迫,其中20%血清培养浓度为正常对照组,15%、10%、5%和0%血清培养浓度为试验组。细胞... 详细信息

为了探究长时间、不同程度饥饿胁迫条件对原代猪骨骼肌卫星细胞(SMSCs)代谢和自噬的影响,本试验通过控制SMSCs培养体系中血清浓度以形成不同程度饥饿胁迫,其中20%血清培养浓度为正常对照组,15%、10%、5%和0%血清培养浓度为试验组。细胞培养96 h后,通过流式细胞术检测各组细胞凋亡率、线粒体膜电位和活性氧(ROS)水平,通过ATP检测试剂盒测定细胞内ATP水平,通过Western blot检测各组细胞蛋白中自噬标志蛋白LC3b、p62以及AMPK-mTOR自噬信号通路中p-AMPK/AMPK和p-mTOR/mTOR蛋白的表达。结果显示,与20%血清组相比,0%血清和5%血清细胞凋亡率极显著上调(P<0.01),10%血清组细胞凋亡率显著上调(P<0.05);各试验组线粒体膜电位均极显著下降(P<0.01),ROS水平和ATP水平均极显著上调(P<0.01);细胞中LC3b蛋白的相对表达量随血清浓度降低而升高,p62蛋白的相对表达量随血清浓度降低而降低;p-mTOR/mTOR比值随血清浓度降低而降低,p-AMPK/AMPK比值随血清浓度降低而升高。结果表明,通过长期减少SMSCs培养体系中血清浓度,可以促进细胞代谢加快和凋亡发生,并且通过AMPK/mTOR信号通路激发细胞发生自噬,上述变化的程度与血清减少的程度呈正相关。本试验为后续探索不同程度饥饿胁迫对动物肌肉发育影响的研究提供理论依据。

关键词：血清饥饿自噬细胞代谢 AMPK/mTOR通路骨骼肌卫星细胞

铝酸盐水泥结合莫来石不定形浇注料耐高温性能研究

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新型建筑材料 2024年第8期51卷 112-116,122页

作者：李宣霖文华周锦程雷旭范伟蒋李志鸿西南科技大学土木工程与建筑学院四川绵阳621010

采用不同类型的铝酸盐水泥与电熔莫来石制成莫来石不定形耐火浇注料,研究了在不同温度煅烧后的线变化率、显气孔率、体积密度、力学性能及荷重软化温度的变化,采用XRD、SEM及EDS对物相组成及微观形貌进行分析。结果表明,线变化率在不同... 详细信息

采用不同类型的铝酸盐水泥与电熔莫来石制成莫来石不定形耐火浇注料,研究了在不同温度煅烧后的线变化率、显气孔率、体积密度、力学性能及荷重软化温度的变化,采用XRD、SEM及EDS对物相组成及微观形貌进行分析。结果表明,线变化率在不同温度煅烧后均呈收缩的趋势,显气孔率随煅烧温度升高不断增大,体积密度随煅烧温度升高先减小而后增大;莫来石质浇注料经不同高温煅烧后,其抗折强度随温度升高不断提高,抗压强度随温度升高不断降低;使用CA80水泥、CA70水泥制备的耐火浇注料荷重软化温度最高,分别为1462、1442℃。

关键词：铝酸盐水泥莫来石不定形浇注料荷重软化温度

Two families of Niho sequences having four-valued cross correlation with m-sequences Dedicated to Professor yingbo Zhang on the Occasion of His 70th Birthday

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Science China Mathematics 2017年第12期60卷 2377-2390页

作者： fan jinMei xu YunGe XIA YongBo ZENG XiangYong Faculty of Mathematics and Statistics Hubei Key Laboratory of Applied MathematicsHubei University College of Science Guilin University of Technology Department of Mathematics and Statistics South-Central University for Nationalities

For two odd integers m and s with 1≤s < m and gcd(m, s) = 1, let h satisfy h(2~s-1) ≡1(mod 2~m+ 1) and d =(h + 1)(2~m-1) + 1. The cross correlation function between a binary m-sequence of period 22~m-1 and its d-decimation sequence is proved to take four values, and the correlation distribution is completely determined. Let n be an even integer and k be an integer with 1≤k≤n/2. For an odd prime p and a p-ary m-sequence {s(t)} of period p^n-1, define u(t) =∑(p^k-1)/2 i=0 s(d_it), where d_i = ip^(n/2) + p^k-i and i = 0, 1,...,(p^k-1)/2. It is proved that the cross correlation function between {u(t)} and {s(t)} is three-valued or four-valued depending on whether k is equal to n/2 or not, and the distribution is also determined.

关键词： m-sequence decimation sequence correlation distribution Niho exponent exponential sum

The time and frequency standard system for FAST receivers

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Research in Astronomy and Astrophysics 2020年第5期20卷 148-154页

作者： Kai Zhu jin fan Kun Liang Wei Tang Zhi-Sheng gao Yan Zhu Yi Feng Wei-Wei Zhu Lei Qian You-Ling Yue jin-You Song Xiang-Wei Shi Xing-Yi Wang Ming-Lei Guo Hang Zhang Heng-Qian Gan hong-Fei Liu Cheng-jin jin Peng Jiang National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China National Institute of Metrology Beijing 100013China

This paper reports on the time and frequency standard system for the Five-hundred meter Aperture Spherical radio Telescope(FAST),including the system design,stability measurements and pulsar timing *** stability and drift rate of the frequency standard are calculated using 1-year monitoring *** UTC-NIM Disciplined Oscillator(NIMDO)system improves the system time accuracy and stability to the level of 5 *** timing observations were carried out for several *** weighted RMS of timing residuals reaches the level of less than 3.0μs.

关键词： FAST:radio telescope time frequency standard NIMDO:UTC-NIM

In Silico Screening of Potential Chinese Herbal Medicine Against COVID-19 by Targeting SARS-CoV-2 3CLpro and Angiotensin Converting Enzyme Ⅱ Using Molecular Docking

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Chinese Journal of Integrative Medicine 2020年第7期26卷 527-532页

作者： gao Liang-qin xu jing CHEN Shao-dong Department of Traditional Chinese Medicine Xiamen University HospitalXiamen UniversityXiamenFujian Provinee(361005)China College of Ocean and Earth Sciences Xiamen UniversityXiamenFujian Provinee(361102)China Department of Traditional Chinese Medicine School of MedicineXiamen UniversityXiamenFujian Provinee(361002)China

Objective:To seek potential Chinese herbal medicine(CHM)for the treatment of coronavirus disease 2019(COVID-19)through the molecular docking of the medicine with SARS-CoV-23 CL hydrolytic enzyme and the angiotensin converting enzymeⅡ(ACE2)as receptors,using computer virtual screening technique,so as to provide a basis for combination ***:The molecular docking of CHM with the SARS-Cov-23 CL hydrolase and the ACE2 converting enzyme,which were taken as the targets,was achieved by the Autodock Vina *** CHM monomers acting on 3 CLpro and ACE2 receptors were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform,the active ingredients were selected,and the key CHMs and compounds were *** on the perspective of network pharmacology,the chemical-target network was constructed,and the functional enrichment analysis of gene ontology and the pathway enrichment analysis of Kyoto encyclopedia of genes and genomes were carried out by DAVID to speculate about the mechanism of action of the core drug ***:There are6 small molecule compounds that have the optimal binding energy with the two target *** 238 potential anti-COVID-19 herbs screened in total,16 kinds of CHM containing the most active ingredients,and5 candidate anti-COVID-19 herbs that had been used in high frequency,as well as a core drug pair,namely,Forsythiae Fructus-Lonicerae Japonicae Flos were ***:The core drug pair of Forsythiae Fructus-Lonicerae Japonicae Flos containing multiple components and targets is easy to combine with 3 CLpro and ACE2,and exerts an anti-COVID-19 pneumonia effect through multi-component and multi-target,and plays the role of anti-COVID-19 pneumonia in multi-pathway.

关键词： molecular docking COVID-19 SARS-CoV-23CL hydrolytic enzyme angiotensin converting enzymeⅡ Chinese medicine

Chiral Anomaly in Non-Relativistic Systems:Berry Curvature and Chiral Kinetic Theory

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Chinese Physics Letters 2022年第2期39卷 21-27页

作者： Lan-Lan gao xu-Guang Huang Physics Department and Center for Particle Physics and Field Theory Fudan UniversityShanghai 200438China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Fudan UniversityShanghai 200433China

Chiral anomaly and the novel quantum phenomena it induces have been widely studied for Dirac and Weyl *** most typical cases,the Lorentz covariance is assumed and thus the linear dispersion relations are ***,in realistic materials,such as Dirac and Weyl semimetals,the nonlinear dispersion relations appear *** develop a kinetic framework to study the chiral anomaly for Weyl fermions with nonlinear dispersions using the methods of Wigner function and semi-classical equations of *** this framework,the chiral anomaly is sourced by Berry monopoles in momentum space and could be enhanced or suppressed due to the windings around the Berry *** results can help understand the chiral anomaly-induced transport phenomena in non-relativistic systems.

关键词： motion Berry Chiral

Meteorin-β/Meteorin like/IL-41 attenuates airway inflammation in house dust mite-induced allergic asthma

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Cellular & Molecular Immunology 2022年第2期19卷 245-259页

作者： xun gao ting-fan Leung Gary Wing-Kin Wong Wing-Hung Ko Mengyun Cai Ellie Jiayi He Ida Miu-ting Chu Miranda Sin-Man Tsang Ben Chung-Lap Chan Jiawei Ling Xiao fan Liwei Lu Christopher Wai-Kei Lam Chun-Kwok Wong Department of Chemical Pathology The Chinese University of Hong KongHong KongChina Department of Paediatrics The Chinese University of Hong KongHong KongChina School of Biomedical Sciences The Chinese University of Hong KongHong KongChina Emory College of Arts and Sciences Emory UniversityAtlantaGAUSA Institute of Chinese Medicine and State Key Laboratory of Research on Bioactivities and Clinical Applications of Medicinal Plants The Chinese University of Hong KongHong KongChina Department of Pathology and Shenzhen Institute of Research and Innovation The University of Hong KongHong KongChina Faculty of Medicine and State Key Laboratory of Quality Research in Chinese Medicines Macao University of Science and TechnologyMacaoChina Li Dak Sum Yip Yio Chin R&D Centre for Chinese Medicine The Chinese University of Hong KongHong KongChina

We sought to examine the regulatory effect of Meteorin-β(Metrnβ)/Meteorin like(Metrnl)/IL-41 on lung inflammation in allergic *** found that Metrnβwas elevated significantly in asthmatic patients and in mice with allergic asthma induced by house dust mite(HDM)*** exposure to HDM,Metrnβwas secreted predominantly by airway epithelial cells and inflammatory cells,including macrophages and *** increased Metrnβeffectively blocked the development of airway hyperreactivity(AHR)and decreased inflammatory cell airway infiltration and type 2 cytokine production,which was associated with downregulated DC-mediated adaptive immune ***,Metrnβimpaired the maturation and function of bone marrow-derived dendritic cells in *** mice adoptively transferred with dendritic cells isolated from Metrnβ-treated allergic mice displayed decreased AHR,airway inflammation,and lung ***βalso displayed anti-inflammatory properties in immunodeficient SCID mice with allergic asthma and in in vitro 3D ALI airway ***,blockade of Metrnβby anti-Metrnβantibody treatment promoted the development of allergic *** results revealed the unappreciated protective roles of Metrnβin alleviating DC-mediated Th2 inflammation in allergic asthma,providing the novel treatment strategy of therapeutic targeting of Metrnβin allergic asthma.

关键词： Metrnβ Eosinophils Dendritic cells Allergic asthma Air-liquid interface