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Acute toxicity and chromosomal aberration toxicity of insect wax and its policosanol

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Food Science and Human Wellness 2022年第2期11卷 356-365页

作者： Jinju Ma Kun Li Wenwen Zhang Liyi Ma juan xu Lanxiang Liu Xiaoming Chen Hong Zhang Peculiar Biological Resources Technology Engineering Center Research Institute of Resources InsectsChinese Academy of ForestryKunming 650224China

An acute toxicity test in Sprague Dawley(SD)rats and a chromosomal aberration toxicity test in Chinese hamster lung(CHL)fibroblasts were conducted to promote the application of insect wax and its *** of oral acute toxicity test showed that the LD;values of insect wax and its policosanol were higher than 5000 mg/*** rats showed no obvious toxic symptoms and survived,suggesting that these substances were not *** chromosomal aberration rates of the CHL cells incubated with insect wax for 3-6 h under metabolic activation conditions and for 3-6 h and 24 h under non-metabolic activation conditions were lower than 5%.No significant difference was found compared with the negative control ***,no significant difference in chromosomal aberration rates was found between each dose group of policosanol under metabolic or non-metabolic activation conditions and the negative control ***,the chromosomal aberration rates of CHL cells treated with insect wax and its policosanol were negative regardless of metabolic activation *** results indicate the absence of acute toxicity and potential chromosomal aberration in the tested dose range of insect wax and its policosanol.

关键词： Insect wax Policosanol from insect wax Acute toxicity Chromosomal aberration

Acute gastric volvulus combined with pneumatosis coli rupture misdiagnosed as gastric volvulus with perforation:A case report

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World Journal of Gastrointestinal Surgery 2024年第10期16卷 3350-3357页

作者： Qi Zhang Xiu-juan xu Jun Ma Hai-Ying Huang Ya-Ming Zhang Department of General Surgery Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina Department of Critical Medicine Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina Department of Gastroenterology Anqing Municipal HospitalAnqing 246000Anhui ProvinceChina

BACKGROUND Acute gastric volvulus represents a rare form of surgical acute abdomen,which makes it difficult to establish an early *** the disease progresses,it can lead to gastric ischemia,necrosis,and other serious *** SUMMARY This paper reports a 67-year-old female patient with a history of abdominal distension and retching for 1 *** admission,a prompt and thorough exami-nation was performed to confirm the diagnosis of acute gastric ***,the patient had free air in the abdominal *** first consideration was gastric volvulus with gastric perforation,but the patient had no complaints,such as abdominal pain or signs of peritoneal irritation in the abdomen,and imaging examination revealed no abdominal pelvic *** endoscopic reduc-tion,the abdominal organs,such as the stomach and spleen,returned to their normal anatomical positions,and the free intraperitoneal air disappeared,su-ggesting a rare case of acute gastric *** source of free air within the abdominal cavity warrants careful consideration and *** with the findings from computed tomography,these findings are hypothesized to be associated with the rupture of colonic air *** Patients with gastric torsion combined with free gas in the abdominal cavity should consider nongastrointestinal perforation factors to avoid misdiagnosis.

关键词： Acute gastric volvulus Free intraperitoneal air Endoscopic therapy Pneumatosis intestinalis cyst Case report

Construction of the yeast whole-cell Rhizopus oryzae lipase biocatalyst with high activity

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第7期12卷 545-551页

作者： Mei-ling CHEN Qin GUO Rui-zhi WANG juan xu Chen-wei ZHOU Hui RUAN Guo-qing HE Department of Food Science and Nutrition Zhejiang University Hangzhou 310029 China School of Food and Biological Engineering Jiangsu University Zhenjiang 212013 China

Surface display is effectively utilized to construct a whole-cell *** optimization has been proven to be effective in maximizing production of heterologous proteins in ***,the cDNA sequence of Rhizopus oryzae lipase (ROL) was optimized and synthesized according to the codon bias of Saccharomyces cerevisiae,and based on the Saccharomyces cerevisiae cell surface display system with α-agglutinin as an anchor,recombinant yeast displaying fully codon-optimized ROL with high activity was successfully *** with the wild-type ROL-displaying yeast,the activity of the codon-optimized ROL yeast whole-cell biocatalyst (25 U/g dried cells) was 12.8-fold higher in a hydrolysis reaction using p-nitrophenyl palmitate (pNPP) as the *** our knowledge,this was the first attempt to combine the techniques of yeast surface display and codon optimization for whole-cell biocatalyst ***,the yeast whole-cell ROL biocatalyst was constructed with high *** optimum pH and temperature for the yeast whole-cell ROL biocatalyst were pH 7.0 and 40 °***,this whole-cell biocatalyst was applied to the hydrolysis of tributyrin and the resulted conversion of butyric acid reached 96.91% after 144 h.

关键词： Rhizopus oryzae lipase (ROL) Yeast surface display Codon optimization Whole-cell biocatalyst

A Study on Foreign Capital M&A of Agribusiness

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Asian Agricultural Research 2016年第7期8卷 21-23,26页

作者： juan xu College of Economics and Management Huazhong Agricultural University

After joining the WTO,Chinese government has gradually fulfilled various promises,such as cancellation of restrictions on foreign capital share ratio,and opening up of foreign investment areas. There are new changes in foreign merchants' direct investment in China,and it shifts from " green investment" featured by high risk and long period of return on investment to cross-border M&A. Since Coca-Cola failed to complete M&A of Huiyuan Juice in 2009,people have paid close attention to foreign capital M&A of domestic agribusiness. New changes and features appear in both scale and industrial areas,and M&A incidents have mushroomed in the industries of meat processing,wine,dairy and beverage,and the related industries have become the hot areas of cross-border M&A. Through the study of M&A incidents in China's agriculture-related areas in recent years,this paper aims to offer an overview of current foreign capital M&A of China's agribusiness in terms of scale and industry.

关键词： Foreign capital M&A Agribusiness Scale change Industrial change

Frequency of Food Consumption Among Students Aged 8–15 Years—China,2019 and 2021

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China CDC weekly 2023年第24期5卷 533-537页

作者： Yimeng Fu juan xu Qian Gan Titi Yang Peipei xu Wei Cao Hongliang Wang Hui Pan Ruihe Luo Wenxin Sun Zhifang Wang Qian Zhang National Institute for Nutrition and Health Chinese Center for Disease Control and PreventionBeijingChina

A balanced consumption of various types of food items plays a crucial role in students’physical and intellectual development,providing the foundation for their lifelong health(1).In recent years,the living standards in China have improved,leading to a steady improvement in the intake of various foods among Chinese students(2).However,uneven socioeconomic development and differing natural environments may lead to disparities in food consumption between rural and urban students(3).The prevalence of malnutrition among rural students has decreased but remains higher than among urban students(4).Furthermore,consumption of various healthy foods increased during the coronavirus disease 2019(COVID-19)pandemic as a means to boost immunity and promote health(5).

关键词： immunity boost intake

Effects of severe obstructive sleep apnea on functional prognosis in the acute phase of ischemic stroke and quantitative electroencephalographic markers

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Effects of severe obstructive sleep apnea on functional prog...

Superderivations for a Family of Lie Superalgebras of Special Type

中国睡眠研究会第十五届全国学术年会

作者： juan xu The Second Affiliated Hospital of Soochow University

Objective: To investigate the effect of severe obstructive sleep apnea(OSA) on functional prognosis in the acute phase and quantitative electroencephalography(EEG) markers during sleep in ischemic stroke ***: This study included 125 mild-to-moderate acute ischemic stroke patients with OSA who underwent polysomnography(PSG) within one week of stroke onset between January 2015 and June *** were grouped according to their apnea-hypopnea index(≥ 30/h).Poor functional prognosis was defined as modified Rankin Scale score ≥ *** EEG recorded by PSG was extracted during different sleep stages for power spectrum *** delta/alpha power ratio(DAR),(delta t theta)/(alpha t beta) ratio(the slowing ratio, TSR), and the relative power(RP) of each frequency band were *** in clinical, PSG, and quantitative EEG characteristics were compared between the ***, we explored predictors of poor functional ***: Patients with severe OSA had a higher proportion of hypertension, lower relative power of high-frequency bands, and higher delta RP, TSR, and DAR(p < 0.05).Severe OSA was associated with a 3.6-fold increase in risk of poor prognosis(p < 0.05).Increased delta RP and TSR, as well as decreased alpha, beta, and sigma RP, may be independent predictors of a poor functional ***: Severe OSA is an independent risk factor for a poor functional prognosis in patients with acute ischemic stroke, and quantitative EEG during sleep showed a significant slow wave enhancement, suggesting more severe brain *** treatment of severe OSA may improve functional prognosis.

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来源： cnki会议评论

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Communications in Mathematical Research 2011年第1期27卷 53-61页

作者： SUN XIU-MEI ZOU xu-juan LIU WEN-DE School of Mathematical Sciences Harbin Normal University Harbin 150025

By means of generators, superderivations are completely determined for a family of Lie superalgebras of special type, the tensor products of the exterior algebras and the finite-dimensional special Lie algebras over a field of characteristic p〉3. In particular, the structure of the outer superderivation algebra is concretely formulated and the dimension of the first cohomology group is given.

关键词： divided power algebra special algebra superderivation

Zuo Gui Wan Promotes Osteogenesis via PI3K/AKT Signaling Pathway:Network Pharmacology Analysis and Experimental Validation

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Current Medical Science 2023年第5期43卷 1051-1060页

作者： Shuo YANG Bin ZHANG Yu-guo WANG Zi-wei LIU Bo QIAO juan xu Li-sheng ZHAO Department of Stomatology The First Medical CenterChinese PLA General HospitalBeijing 100853China Department of Traditional Chinese Medicine Chinese PLA General HospitalBeijing 100853China

Objective Osteogenesis is vitally important for bone defect repair,and Zuo Gui Wan(ZGW)is a classic prescription in traditional Chinese medicine(TCM)for strengthening ***,the specific mechanism by which ZGW regulates osteogenesis is still *** current study is based on a network pharmacology analysis to explore the potential mechanism of ZGW in promoting *** A network pharmacology analysis followed by experimental validation was applied to explore the potential mechanisms of ZGW in promoting the osteogenesis of bone marrow mesenchymal stem cells(BMSCs).Results In total,487 no-repeat targets corresponding to the bioactive components of ZGW were screened,and 175 target genes in the intersection of ZGW and osteogenesis were *** 28 core target genes were then obtained from a PPI network analysis.A GO functional enrichment analysis showed that the relevant biological processes mainly involve the cellular response to chemical stress,metal ions,and ***,KEGG pathway enrichment analysis revealed that multiple signaling pathways,including the phosphatidylinositol-3-kinase/protein kinase B(PI3K/AKT)signaling pathway,were associated with ZGW-promoted *** experimental validation showed that ZGW could increase alkaline phosphatase(ALP)activity as well as the mRNA and protein levels of ALP,osteocalcin(OCN),and runt related transcription factor 2(Runx 2).What’s more,Western blot analysis results showed that ZGW significantly increased the protein levels of p-PI3K and p-AKT,and the increases of these protein levels significantly receded after the addition of the PI3K inhibitor ***,the upregulated osteogenic-related indicators were also suppressed by the addition of *** ZGW promotes the osteogenesis of BMSCs via PI3K/AKT signaling pathway.

关键词： Zuo Gui Wan network pharmacology bone marrow mesenchymal stem cells osteogenesis PI3K/AKT signaling pathway

A Game Theory Analysis of the OPEC’s Influence on World Oil Price

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Petroleum Science 2006年第4期3卷 21-25页

作者： Wang Zhen xu juan Wang Hongyan School of Business Administration China University of Petroleum Beijing 102249 China

Most studies concerning OPEC＇s behavior assumptions about oil market structure are either very were based on traditional market microstructure. However, the rigorous or rather fuzzy. This paper demonstrates the rationality and necessity of OPEC＇s price band policy by using the game theory. We conclude that OPEC has the incentive to limit its price within a specific range if the game period is sufficiently long. This incentive comes either from preference for long-term interest or from future expectations. In such a way, OPEC tries its best to maximize its profit with the quota-price dual policy and plays a price stabilizing role in the future world oil market.

关键词： Price band policy OPEC game theory equilibrium