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Photonics Research 2016年第2期4卷 45-48页

作者： Z.y.xu y.h.Li L.J.Wang Joint Institute for Measurement Science Tsinghua University Shanghai Institute of Laser Plasma State Key Laboratory of Precision Measurement Technology and Instruments Tsinghua University

We demonstrated long-period grating(LPG) inscription on polymer functionalized optical microfibers and its applications in optical sensing. Optical microfibers were functionalized with ultraviolet-sensitive polymethyl methacrylate jackets and, thus, LPGs could be inscribed on optical microfibers via point-by-point ultraviolet laser exposure. For a 2 mm long microfiber LPG(MLPG) inscribed on optical microfibers with a diameter of 5.4 μm, a resonant dip of 15 d B at 1377 nm was observed. This MLPG showed a high sensitivity of strain and axial force, i.e.,-1.93 pm∕με and-1.15 pm∕μN, respectively. Although the intrinsic temperature sensitivity of the LPGs is relatively low, i.e.,-12.75 pm∕°C, it can be increased to be-385.11 pm∕°C by appropriate sealing. Benefiting from the small footprint and high sensitivity, MLPGs could have potential applications in optical sensing of strain,axial force, and temperature.

关键词： MLPG Long-period grating inscription on polymer functionalized optical microfibers and its applications in optical sensing

Trimetallic mesoporous PdCuRu for efficient formate electrosynthesis from polyethylene terephthalate recycling

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Science China Chemistry 2025年

作者： yuting Li huiqin yao Lizhi Sun Shu han Xiaoxiang xu Guangyin Fan Ben Liu College of Chemistry and Materials Science Sichuan Normal University Key Laboratory of Green Chemistry and Technology of Ministry of Education College of Chemistry Sichuan University School of Basic Medical Sciences Ningxia Medical University Department of Otorhinolaryngology.h.ad and Neck Surgery Zhongnan Hospital of Wuhan University

Electrochemical recycling of waste polyethylene terephthalate（PET） plastics represents a green and sustainable route to produce valuable fuels and address serious environmental issues. Despite some encouraged achievements, their progress is still slower because of the lack of highly active and selective electrocatalysts. here, we reported an efficient PET recycling route with trimetallic PdCuRu mesoporous nanospheres（MSs） as a high-performance electrocatalyst that achieved selective electrosynthesis of valuable formate from PET hydrolysate（PETh） electrooxidation. Penetrated metal mesopores and trimetallic compositions of PdCuRu MSs synergistically optimized electronic structures of Pd sites and changed chemisorption properties of intermediates, which disclosed a high formate Faradic efficiency of 97% and impressive yield rate of 0.49 mmol h-1cm-2in an alkaline solution. Meanwhile, this electrocatalyst held good electrocatalytic stability, retaining high formate Faradic efficiency and yield rate even being performed for 10 cycles, which highlighted its potential applications for practical PET recycling. Our study provides a powerful strategy for designing high-performance electrocatalysts toward selective electro-synthesis of valuable fuels from various waste plastics.

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Transient chemical-mediated epigenetic modulation confers unrestricted lineage potential on human primed pluripotent stem cells

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Science China Life Sciences 2025年

作者： Shi Chen yuanyuan he Lejun Lv Bei Liu Cheng Li hongkui Deng Jun xu Department of Cell Biology School of Basic Medical Sciences Peking University Stem Cell Research Center Peking University Health Science Center Peking University Academy of Advanced Interdisciplinary Studies Peking University BeiCell Therapeutics School of Life Sciences Center for Bioinformatics Center for Statistical Science Peking University MOE Engineering Research Center of Regenerative Medicine School of Basic Medical Sciences State Key Laboratory of Natural and Biomimetic Drugs Peking University Health Science Center and the MOE Key Laboratory of Cell Proliferation and Differentiation College of Life Sciences Peking-Tsinghua Center for Life Sciences Peking University

human primed pluripotent stem cells are capable of generating all the embryonic ***,their extraembryonic trophectoderm potentials are *** remains unclear how to expand their developmental potential to trophectoderm *** we show that transient treatment with a cocktail of small molecule epigenetic modulators imparts trophectoderm lineage potentials to human primed pluripotent stem cells while preserving their embryonic *** chemically treated cells can generate trophectoderm-like cells and downstream trophoblast stem cells,diverging into syncytiotrophoblast and extravillous trophoblast *** and CUT&Tag analyses reveal that these induced cells share transcriptional profiles with in vivo trophectoderm and cytotrophoblast,and exhibit reduced h3K27me3 modification at gene loci specific to trophoblast lineages compared with primed pluripotent *** exploration highlighted the critical roles of epigenetic modulators hDAC2,EZh1/2,and KDM5s in the activation of trophoblast lineage *** findings demonstrate that transient epigenetic resetting activates unrestricted lineage potential in human primed pluripotent stem cells,and offer new mechanistic insights into human trophoblast lineage specification and in vitro models for studying placental development and related disorders.

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Impact Factors on Fracturing Results of Coal Seams and Appropriate Countermeasures

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Journal of Energy and Power Engineering 2010年第6期4卷 16-26页

作者： X. Wang y.h. Ding y. xu y.y. Duan Fracturing ＆ Acidizing Technical Service Center Research Institute of Petroleum Exploration and Development China NationalPetroleum Corp. Langfang 065007 China

hydraulic fracturing is one of the efficient means for the abundant low-permeability CBM （coal-bed methane） reserves in China, however, due to the unique features of coal seams （i.e., low temperature, strong adsorption and abnormal development of natural fracture systems） as compared with the conventional reservoirs, the fractures propagate is difficult and the risk of damage to coal seam itself and the hydraulic fractures would be extremely.h.gh in the course of fracturing. As a result, losses would be suffered on the post-frac production of CBM *** the mean of numerical simulation, in this paper, the main factors have impact on the post-frac results as well as the extent to which the impact is brought were researched, and the technical solutions for the improvement of the fracturing performance was put forwards.

关键词： Coal-seam fracturing hazard factors yield loss rate technical solutions.

Carbonylation　of　Allyl　Chloride　Catalyzed　by　PdCl_2（TPPTS）_2　in　Two－phase　Medium

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Chinese Chemical Letters 1996年第9期7卷 847-848页

作者： Jiang, h xu, y Liao, SJ yu, DR Chen, h Li, XJ ChINESE ACAD SCI DALIAN INST CHEM PHYSDALIAN 116023PEOPLES R CHINA SIChUAN UNIV DEPT CHEMCHENGDU 610064PEOPLES R CHINA

PdCl2(TPPTS)2 exhibits very.h.gh catalytic activity for carbonylation of allyl chloride in aq. NaOh / toluene two-phase medium under atmospheric *** average turnover frequency (TOFav,mol substrate / mol Pd·min) reach... 详细信息

关键词： TPPTS PdCl2 Two Catalyzed phase Allyl Carbonylation

Flux focusing with a superconducting nanoneedle for scanning SQUID susceptometry

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Microsystems & Nanoengineering 2023年第3期9卷 411-417页

作者： B.K.Xiang S.y.Wang y.F.Wang J.J.Zhu h.T.xu y.h.Wang State Key Laboratory of Surface Physics and Department of Physics FudanUniversity200433 ShanghaiChina Shanghai Research Center for Quantum Sciences 201315 ShanghaiChina

A nanofabricated superconducting quantum interference device(nano-SQUID)is a direct and sensitive flux probe used for magnetic imaging of quantum materials and mesoscopic *** to the functionalities of superconductive integrated circuits,nano-SQUIDs fabricated on chips are particularly versatile,but their spatial resolution has been limited by their planar ***,we use femtosecond laser 3-dimensional(3D)lithography to print a needle onto a nano-SQUID susceptometer to overcome the limits of the planar *** nanoneedle coated with a superconducting shell focused the flux from both the field coil and the *** performed scanning imaging with such a needle-on-SQUID(NoS)device on superconducting test patterns with topographic *** NoS showed improved spatial resolution in both magnetometry and susceptometry relative to the planarized *** work serves as a proof-of-principle for integration and inductive coupling between superconducting 3D nanostructures and on-chip Josephson nanodevices.

关键词： lithography SQUID needle

FUZZy REGRESSION MODEL TO PREDICT ThE BEAD GEOMETRy IN ThE ROBOTIC WELDING PROCESS

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Acta Metallurgica Sinica(English Letters) 2007年第6期20卷 391-397页

作者： B.S. Sung I.S. Kim y. xue h.h. Kim y.h. Cha Department of Material Engineering Chosun University 375 Seosul-Dong Dong-GuGwangju 501-759 Korea Department of Mechanical Engineering Mokpo National University 61 Dorim-riChungkye-Myun Muan-Gun Jconnam 534-729 Korea Department of Mechanical Engineering Chosun University 375 Seosul-Dong Dong-GuGwangju 501-759 Korea

Recently, there has been a rapid development in computer technology, which has in turn led to develop the fully robotic welding system using artificial intelligence （AI） technology. however, the robotic welding system has not been achieved due to difficulties of the mathematical model and sensor technologies. The possibilities of the fuzzy regression method to predict the bead geometry, such as bead width, bead height, bead penetration and bead area in the robotic GMA （gas metal arc） welding process is presented. The approach, a well-known method to deal with the problems with a high degree of fuzziness, is used to build the relationship between four process variables and the four quality characteristics, respectively. Using these models, the proper prediction of the process variables for obtaining the optimal bead geometry can be determined.

关键词： robotic arc welding bead geometry fuzzy regression modelwelding quality

CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system

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Neural Regeneration Research 2025年第8期20卷 2420-2432页

作者： Lin yin yalan xu Jie Mu yu Leng Lei Ma yu Zheng Ruizhi Li yin Wang Peifeng Li hai Zhu Dong Wang Jing Li Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina School of Basic Medicine Qingdao UniversityQingdaoShandong ProvinceChina College of Life Sciences and School of PharmacyMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina Department of Urology Qingdao Municipal Hospital Affiliated to Qingdao UniversityQingdaoShandong ProvinceChina

The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding *** of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully *** has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic ***,the function of CNKSR2 in the cytoplasm remains to be *** this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of *** a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the *** also showed that CNKSR2 interacted with the microtubule protein DyNC1h1 and with the centrosome marker *** colocalization analysis confirmed the centrosomal localization of *** we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal *** manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and ***,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum *** findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.

关键词： autism spectrum disorder centrosome CNKSR2 intellectual disability interactome mass spectrometry microtubule neurodevelopmental disease protein complexes protein-protein interactions

Multivariate synergy for heightening ionic hOF robustness and proton conductivity

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Science China Chemistry 2025年

作者： Xiang-Tian Bai Li-hui Cao xu-yong Chen Jia-yu Wang Zi-ye Zhou Shaanxi Key Laboratory of Chemical Additives for Industry College of Chemistry and Chemical EngineeringShaanxi University of Science and Technology

Multicomponent crystalline materials construct more complex and diversified structures with different combinations and modes,which expands the material structure space and application *** this work,we have successfully synthesized two twocomponent ionic hydrogen-bonded organic frameworks （ihOF-32 and ihOF-33） and a three-component ihOF （ihOF-34）.Guanidine hydrochloride which is rich in N and h and has a short chain length strengthens the hydrogen bonding network of ihOF,thereby aiding in the efficient migration of *** rigid architecture of 1,1'-diamino-4,4'-bipyridine diiodide furnishes additional scaffolding for the ihOFs and enhances its robustness under harsh ***-34 accomplishes the combination of the ultra-high proton conductivity of ihOF-32 and the robustness of ihOF-33 by the synergistic interaction among the three components of *** addition,ihOF-34 was fabricated as a composite membrane with a peak proton conductivity of 1.55×10-1S cm-1,which is 3.8 times higher than that of recast Nafion,and has extensive potential in fuel *** self-assembly strategy of multicomponent hOFs opens up new avenues for constructing diverse structures while promising new opportunities for applications in the fields of proton conduction and energy storage.

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Leveraging ROTI map derived from Indonesian GNSS receiver network for advancing study of Equatorial Plasma Bubble in Southeast/East Asia

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Earth and Planetary Physics 2025年第1期9卷 101-116页

作者： Prayitno Abadi Ihsan N.Muafiry Teguh N.Pratama Angga y.Putra Suraina Gatot h.Pramono Sidik T.Wibowo Febrylian F.Chabibi Umar A.Ahmad Wildan P.Tresna Asnawi Research Center for Climate and Atmosphere Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia School of Electrical Engineering Telkom UniversityBandungIndonesia Directorate of Laboratory Management Facilities and Science and Technology Park Indonesian National Research and Innovation Agency(BRIN)PontianakIndonesia Geophysics Laboratory Master Program in PhysicsUniversitas Gadjah Mada(UGM)YogyakartaIndonesia Research Center for Space Indonesian National Research and Innovation Agency(BRIN)BandungIndonesia Indonesian Geospatial Information Agency(BIG) JakartaIndonesia Research Center for Photonics Indonesian National Research and Innovation Agency(BRIN)Tangerang SelatanIndonesia Department of Earth and Planetary Sciences Hokkaido UniversitySapporoJapan

This paper highlights the crucial role of Indonesia’s GNSS receiver network in advancing Equatorial Plasma Bubble(EPB)studies in Southeast and East Asia,as ionospheric irregularities within EPB can disrupt GNSS signals and degrade positioning *** by the Indonesian Geospatial Information Agency(BIG),the Indonesia Continuously Operating Reference Station(Ina-CORS)network comprises over 300 GNSS receivers spanning equatorial to southern low-latitude ***-CORS is uniquely situated to monitor EPB generation,zonal drift,and dissipation across Southeast *** provide a practical tool for EPB research,by sharing two-dimensional rate of Total Electron Content(TEC)change index(ROTI)derived from this *** generate ROTI maps with a 10-minute resolution,and samples from May 2024 are publicly available for further scientific *** preliminary findings from the ROTI maps of Ina-CORS are ***,the Ina-CORS ROTI maps reveal that the irregularities within a broader EPB structure persist longer,increasing the potential for these irregularities to migrate farther ***,we demonstrate that combined ROTI maps from Ina-CORS and GNSS receivers in East Asia and Australia can be used to monitor the development of ionospheric irregularities in Southeast and East *** have demonstrated the combined ROTI maps to capture the development of ionospheric irregularities in the Southeast/East Asian sector during the G5 Geomagnetic Storm on May 11,*** observed simultaneous ionospheric irregularities in Japan and Australia,respectively propagating northwestward and southwestward,before midnight,whereas Southeast Asia’s equatorial and low-latitude regions exhibited irregularities *** sharing ROTI maps from Indonesia and integrating them with regional GNSS networks,researchers can conduct comprehensive EPB studies,enhancing the understanding of EPB behavior across Southeast and East Asia and contributing significantly to ionosphe

关键词： Equatorial Plasma Bubble(EPB) GNSS receivers’network Indonesia Continuously Operating Reference Station(Ina-CORS) ionospheric map Rate of TEC change index(ROTI)map