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One-step co-doping of ZnO and Zn^(2+)in osteoinductive calcium phosphate ceramics with synergistic antibacterial activity for regenerative repair of infected bone defect

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Journal of Materials Science & Technology 2023年第32期163卷 168-181页

作者： Tinghan He Hongxu Chen Puxin Liu Hao Shi xiujuan Xu Cong Feng Yuyi Wang Xiangfeng Li Ning lei Yumei Xiao Xiangdong Zhu Jianguo Xu Xingdong Zhang National Engineering Research Center for Biomaterials College of Biomedical EngineeringSichuan UniversityChengdu 610064China College of Materials and Chemistry&Chemical Engineering Chengdu University of TechnologyChengdu 610059China Department of Neurosurgery West China HospitalSichuan UniversityChengdu 610041China

How to endow bone grafts with long-term antibacterial activity and good bone regenerative ability to achieve the regenerative repair of infected bone defects has been the focus of the clinical treatment of *** present study introduced a novel one-step route to realizing the co-doping of zinc oxide(ZnO)and zinc ion(Zn^(2+))in biphasic calcium phosphate(BCP)ceramics to utilize their synergistic *** with the conventional BCP ceramics(BCP-Ca),the ZnO/Zn^(2+)co-doping ones(BCP-Zn)possessed strong antibacterial ability on *** and *** as well as stimulated the osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs)*** synergistic antibacterial mechanism of ZnO and Zn^(2+)was also ***-Zn showed excellent osteoinductivity and angiogenesis at three months postoperatively in the canine intramuscular implantation ***,BCP-Zn exhibited excellent anti-infective ability and bone regenerative repair compared to BCP-Ca and control groups in the infected bone defect model of rat ***,these findings suggest that the simultaneous introduction of ZnO/Zn^(2+)could have immense potential to expand the application of osteoinductive BCP ceramics in the regenerative repair of infected bone defects.

关键词： Biphasic calcium phosphate ceramics Zinc oxide Zinc ion Antibacterial ability Osteoinductivity

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基于产教融合的农业标准化本科课程设置探讨

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特产研究 2023年第3期45卷 183-186页

作者：张瑞李伟李晓薇雷秀娟郑斯文朴向民李婉莹张楠淇王英平吉林农业大学中药材学院吉林长春130118 长春市标准研究院吉林长春130012

本文从国家战略和食品安全等角度,阐述了开设农业标准化本科课程的必要性,并对我国农业标准化本科教育现状进行调研,分析了其中存在的主要问题。针对我国标准化本科教学存在的主要问题,提出了采用“标准化+专业”的教学模式和以产教融... 详细信息

本文从国家战略和食品安全等角度,阐述了开设农业标准化本科课程的必要性,并对我国农业标准化本科教育现状进行调研,分析了其中存在的主要问题。针对我国标准化本科教学存在的主要问题,提出了采用“标准化+专业”的教学模式和以产教融合的方式开展标准化教学的建议,同时在师资队伍建设、教材编写、课程设计和实训保障措施等方面进行了探讨,以期达到培养标准化思维和提高标准化能力的教学目的。

关键词：农业标准化本科教育人才培养

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Ultrasonic Characteristics and Severity Assessment of Lung Ultrasound in COVID-19 Pneumonia:A Retrospective,Observational Study

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Engineering 2021年第3期7卷 367-375页

作者： Fengxue Zhu xiujuan Zhao Tianbing Wang Zhenzhou Wang Fuzheng Guo Haiyan Xue Panpan Chang Hansheng Liang Wentao Ni Yaxin Wang lei Chen Baoguo Jiang Trauma Center Citical Care Medicine DepartmentPeking University People's HospitalBeijing 100044China Trauma Center Key Laboratory of Trauna and Neurad Regeneration(Peling Univerity)Minisiry of EducationPeking Universty Peole's Hiospital lejing 100044China Anesthesioogy Department Peking Uhniversity People's HospitalBeijing 100044China Respiratory and Griticnl Care Medicine Depariment Peking Lniversity People's HospitalBeiing 10004China Raiology Deparment Peking University People's HospitalBeijing 100044China

The clinical application of lung ultrasound(LS)in the assessment of coronavirus disease 2019(COVID-19)pneumonia severity remains limited,Herein,we investigated the role of LUS imaging in CoVID-19pneumonia patients and the relationship between LUS findings and disease *** was a retro-spective,observational study at Tongji Hospital,on 48 recruited patients with COVID-19 pneu-monia,including 32 non-critically ill patients and 16critically ill *** was performed and the respiratory rate oxygenation(ROX)index,disease severity,and confusion,blood urea nitrogen,respira-tory rate,blood pressure,and age(CURB-65)score were recorded on days 0-7,8-14,and 15-21 after *** images were divided into 12 regions,and the luS score(0-36 points)was *** tomography(CT)scores(0-20 points)were also recorded on days *** between the LUS score,ROX index,and CURB-65 scores were *** detected COVID-19 pneumonia in *** signs included B lines(34/38,89.5%),consolidations(6/38,15.8%),and pleural effusions(2/38,5.3%).Most cases showed more than one lesion(32/38,84.2%)and involved both lungs(28/38,73.7%).Compared with non-critically ill patients,the LUS scores of critically ill patients were higher(12(10-18)vs 2(0-5),p<0.001).The LUS score showed significant negative cor-relations with the ROX indexon days O-7(r=-0.85,p<0.001),days 8-14(r=-0.71,p<0.001),and days 15-21(r=-0.76,p<0.001)after symptom ***,the LUS score was positively correlated with the CT score(r=0.82,p<0.001).The number of patients with LUS-detected lesions decreased from 27 cases(81.8%)to 20 cases(46.5%),and the lus scores significantly decreased from 4(2-10)to 0(0-5),(p<0.001) from days O-7 to *** conclude that LUS can detect lunglesions in COVID-19 pneumo-nia patients in a portable,real-time,and safe ***,LUS is helpful in assessing COVID-19 pneu-monia severity in critically ill patients.

关键词： Coronavirus disease 2019 Lung ultrasound Pneumonia

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Comparison Between Electrolysis and Reduction for Treatment of Spent Electroless Nickel Plating Bath

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Journal of Northeast Agricultural University(English Edition) 2009年第2期16卷 23-26页

作者： YAN lei LI Shuqin YU xiujuan Resources and Environmental Sciences College Northeast Agricultural University Harbin 150030 China School of Municipal and Environmental Engineering Harbin Institute of Technology Harbin 150090 China Deptartment of Environmental Science and Engineering Heilongjiang University Harbin 150086 China

There are lots of residual nickel and organic compounds in the spent electroless nickel plating bath. It not only wastes resource but also causes environmental pollution if the wastewater is discharged without treatment. In this paper, electrolytic method and reduction method for treating spent electroless nickel plating bath were compared. The factors studied included reaction time, pH, temperature, effectiveness and cost. It was found that the recovery rate of nickel by reduction was 99.9% under the condition ofpH 6, 50℃ for 10 min. The purity of reclaimed nickel was 66.1%. This treatment needed about 16 g NaBH4 for a liter spent solution, which cost RMB 64 Yuan. For electrolysis method, with pH 7.6, 80℃, 0.45 A （current intensity） for 2 h, the recovery rate reached 97.3%. The purity was 88.5% for the reclaimed nickel. Moreover, it was found that through electrolysis, the value of TOC （Total Organic Carbon） decreased from 114 to 3.08 g·L^-1 with removal rate of 97.3%. The main cost of electrolysis came from electric energy. It cost about 0.09 kWh （less than RMB 0.1 Yuan） per liter wastewater. Compared with reduction, electrolysis had more advantages, so the priority of selection should be given to the electrolysis method for the treatment of spent electroless nickel plating bath.

关键词： spent electroless nickel plating bath electrolysis chemical reduction treatment

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不同浓度聚维酮碘溶液预防异基因造血干细胞移植患者肛周感染的效果研究

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中国实用护理杂志 2024年第12期40卷 889-893页

作者：胡伟郭秀娟张蓓蓓宋岩徐晓东王蕾王佳婷北京大学人民医院血液科北京100044

目的明确不同浓度聚维酮碘溶液预防异基因造血干细胞移植患者肛周感染的效果,为临床开展聚维酮碘坐浴的配制浓度提供依据。方法采用便利抽样法,行类实验研究,选取2019年1月至2020年12月在北京大学人民医院血液科无菌层流病房行异基因造... 详细信息

目的明确不同浓度聚维酮碘溶液预防异基因造血干细胞移植患者肛周感染的效果,为临床开展聚维酮碘坐浴的配制浓度提供依据。方法采用便利抽样法,行类实验研究,选取2019年1月至2020年12月在北京大学人民医院血液科无菌层流病房行异基因造血干细胞移植的727例患者为研究对象,按照入院时间分组,2019年1—12月的患者为对照组358例,2020年1—12月的患者为试验组369例,对照组采用0.0005%聚维酮碘溶液进行坐浴,试验组采用0.005%聚维酮碘溶液进行坐浴,观察并比较2组患者肛周感染发生情况。结果对照组男222例,女136例,年龄32.0(23.0,44.0)岁,试验组男219例,女150例,年龄31.0(21.0,44.0)岁。试验组肛周感染发生率为16.3%(60/369),低于对照组的23.2%(83/358),差异有统计学意义(χ^(2)=5.51,P0.05)。结论坐浴时提高聚维酮碘溶液浓度可降低造血干细胞移植患者肛周感染的发生率,护理人员可在造血干细胞移植患者中应用该方法,以预防患者肛周感染的发生。

关键词：造血干细胞移植聚维酮碘溶液无菌层流病房肛周感染坐浴

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Towards magnetism in pigeon MagR: Iron- and iron-sulfur binding work indispensably and synergistically

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Zoological Research 2023年第1期44卷 142-152页

作者： Yajie Zhou Tianyang Tong Mengke Wei Peng Zhang Fan Fei xiujuan Zhou Zhen Guo Jing Zhang Huangtao Xu lei Zhang Shun Wang Junfeng Wang Tiantian Cai Xin Zhang Can Xie Institutes of Physical Science and Information Technology Anhui UniversityHefeiAnhui 230039China High Magnetic Field Laboratory Hefei Institutes of Physical ScienceChinese Academy of SciencesScience IslandHefeiAnhui 230031China Department of Anatomy Anhui Medical UniversityHefeiAnhui 230032China Science Island Branch of Graduate School University of Science and Technology of ChinaHefeiAnhui 230036China School of Life Sciences Peking UniversityBeijing 100871China International Magnetobiology Frontier Research Center Science IslandHefeiAnhui 230031China Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School250 Longwood AvenueBostonMA 02115USA

The ability to navigate long distances is essential for many animals to locate shelter,food,and breeding *** sense has evolved in various migratory and homing species to orient them based on the geomagnetic field.A highly conserved ironsulfur cluster assembly protein IscA is proposed as an animal magnetoreceptor(MagR).Iron-sulfur cluster binding is also suggested to play an essential role in MagR magnetism and is thus critical in animal *** the current study,we provide evidence for distinct iron binding and iron-sulfur cluster binding in MagR in pigeons,an avian species that relies on the geomagnetic field for navigation and *** MagR showed significantly higher total iron content from both iron-and ironsulfur binding.Y65 in pigeon MagR was shown to directly mediate mononuclear iron binding,and its mutation abolished iron-binding capacity of the ***,both iron binding and iron-sulfur binding demonstrated synergistic effects,and thus appear to be integral and indispensable to pigeon MagR *** results not only extend our current understanding of the origin and complexity of MagR magnetism,but also imply a possible molecular explanation for the huge diversity in animal magnetoreception.

关键词： Animal magnetoreception Iron-sulfur cluster binding Iron binding Magnetism Magnetoreceptor(MagR)

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大麦新品种啤用品质比较分析

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浙江农业科学 2024年第4期65卷 949-952页

作者：蔡康锋郝建秦陈风明岳文浩刘磊夏雪宋秀娟汪军妹浙江省数字旱粮重点实验室浙江杭州310021 中国食品发酵工业研究院北京100015 浙江树人大学浙江杭州310015

以近年育成的7个大麦新品种(系)为材料,分析籽粒和麦芽品质性状以及关键指标之间的相关性。结果表明,供试材料的各项指标品种间存在较大差异。浙皮19号的籽粒品质指标达到国标优级标准。7个品种(系)的α-氨基氮和糖化力均达到行业标准... 详细信息

以近年育成的7个大麦新品种(系)为材料,分析籽粒和麦芽品质性状以及关键指标之间的相关性。结果表明,供试材料的各项指标品种间存在较大差异。浙皮19号的籽粒品质指标达到国标优级标准。7个品种(系)的α-氨基氮和糖化力均达到行业标准优级。相关性分析显示,浸出率与脆度呈显著正相关,α-氨基氮与库尔巴哈值呈显著正相关,黏度与脆度呈极显著负相关。

关键词：大麦籽粒品质麦芽品质相关性

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Analysis of the characteristics of gravity waves during a local rainstorm event in Foshan,China

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Atmospheric and Oceanic Science Letters 2020年第2期13卷 163-170页

作者： WANG xiujuan lei Hengchi FENG Liang ZHU Jiangshan LI Zhaoming JIANG Zhongbao Key Laboratory of Cloud-Precipitation Physics and Severe Storms of Chinese Academy of Sciences Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina Meteorological Observatory of Jilin Province Jilin Province Meteorological BureauChangchunChina Foshan Tornado Research Center Foshan Meteorological BureauFoshanChina Climate Center of Jilin Province Jilin Province Meteorological BureauChangchunChina

A detailed analysis of the dynamic frequency spectrum characteristics of gravity waves(GWs)during a local heavy rainfall event on 20–21 November 2016 in Foshan,China,is *** results of this analysis,which was based on high-precision microbarograph data,indicate that GWs played a key role in generating the *** GWs experienced two intermittent periods of amplitude enhancement and period *** largest amplitudes of the GWs were 80–160 Pa,with a corresponding period range of 140–270 min,which were approximately 4 h ahead of the *** severe storms appeared to affect the GWs by augmenting the wave amplitudes with center amplitudes of approximately 80–100 Pa and periods ranging between 210 and 270 min;in particular,the amplitudes increased to approximately 10 Pa for GWs with shorter periods(less than 36 min).The pre-existing large-amplitude GWs may be precursors to severe storms;that is,these GWs occurred approximately 4 h earlier than the time radars and satellites identified ***,these results indicate that large-amplitude GWs constitute a possible mechanism for severe-storm warning.

关键词： Gravity wave microbarograph dynamic characteristics short period long period amplitude

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CitGVD:a comprehensive database of citrus genomic variations

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Horticulture Research 2020年第1期7卷 2529-2536页

作者： Qiang Li Jingjing Qi xiujuan Qin Wanfu Dou Tiangang lei Anhua Hu Ruirui Jia Guojin Jiang Xiuping Zou Qin Long Lanzhen Xu Aihong Peng Lixiao Yao Shanchun Chen Yongrui He Citrus Research Institute Southwest University/Chinese Academy of Agricultural Sciences400712 ChongqingChina Key Laboratory of Plant Hormones and Development Regulation of Chongqing School of Life SciencesChongqing University401331 ChongqingChina

Citrus is one of the most important commercial fruit crops *** the vast genomic data currently available for citrus fruit,genetic relationships,and molecular markers can be assessed for the development of molecular breeding and genomic selection *** this study,to permit the ease of access to these data,a web-based database,the citrus genomic variation database(CitGVD,http://***/home)was developed as the first citrusspecific comprehensive database dedicated to genome-wide variations including single nucleotide polymorphisms(SNPs)and insertions/deletions(INDELs).The current version(V1.0.0)of CitGVD is an open-access resource centered on 1,493,258,964 high-quality genomic variations and 84 phenotypes of 346 organisms curated from in-house projects and public *** integrates closely related information on genomic variation annotations,related gene annotations,and details regarding the organisms,incorporating a variety of built-in tools for data accession and *** an example,CitGWAS can be used for genome-wide association studies(GWASs)with SNPs and phenotypic data,while CitEVOL can be used for genetic structure *** features make CitGVD a comprehensive web portal and bioinformatics platform for citrus-related *** also provides a model for analyzing genome-wide variations for a wide range of crop varieties.

关键词： database analysis comprehensive

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基于硅橡胶/硼酸锌可瓷化复合多孔材料的制备与阻燃性能

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当代化工 2024年第4期53卷 831-835页

作者：陈子豪黄子通雷丝雨孙良良高秀娟屈昌龙刘翔唐嘉文汪颖景德镇陶瓷大学材料科学与工程学院江西景德镇333000

新能源正处于高速发展的阶段,但是也面临着电池、安全等诸多问题。其中锂电池爆燃问题限制了新能源车的发展。针对这一问题,以有良好附着性的硅橡胶为基体,加入硼酸锌作为阻燃材料,研究复合硅藻土-硅橡胶材料的阻燃性能和高温下的瓷化... 详细信息

新能源正处于高速发展的阶段,但是也面临着电池、安全等诸多问题。其中锂电池爆燃问题限制了新能源车的发展。针对这一问题,以有良好附着性的硅橡胶为基体,加入硼酸锌作为阻燃材料,研究复合硅藻土-硅橡胶材料的阻燃性能和高温下的瓷化效果。通过SEM、XRD、TG等检测方法,对该复合材料进行了表征。结果表明:样品具有良好的阻燃效果。样品内部的硼酸锌在热解条件下产生B2O3,高温煅烧下加速复合硅橡胶的热解并与SiO_(2)发生共熔,促进瓷化过程,产生连续的桥连结构。该研究有助于减缓锂电池的燃烧阻燃问题,降低新能源车的燃烧危害。

关键词：硼酸锌硅橡胶-硅藻土可瓷化阻燃性能

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