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Clinical research progress in Traditional Chinese Medicine in treating wound healing after anal fistula surgery

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中医杂志:英文版 2023年第5期43卷 1047-1054页

作者： MEI Pingping FENG Wenzhe shi Peng ZHANG Wenxiu ZHUANG yu the First Clinical Medical College Department Shaanxi University of Chinese MedicineXianyang 712046China Department of anorectal Affiliated Hospital of Shaanxi University of Chinese MedicineXianyang 712000China

In the study of the mechanism of wound healing after anal fistula surgery,how to scientifically and efficiently promote wound healing is of great *** present,modern medical treatment of wounds after anal fistula surgery mostly focuses on physical therapy intervention,new wound dressing and packing,and external application of growth ***,these therapies have many problems,and there is still no consensus on their clinical *** Chinese Medicine(TCM)has several methods to promote wound healing,such as oral administration,rubbing,and fumigation,which have a long history and obvious efficacy,but research in this area is relatively scattered and lacks classification and ***,this paper analyzes and summarizes the existing research on TCM for promotion of wound healing after anal fistula surgery,carries out targeted analyses according to different clinical syndromes and treatment methods,and analyzes the defects in current research and anticipates future research trends in order to provide theoretical support for the advantages of TCM in promoting wound healing after anal fistula surgery.

关键词： rectal fistula wound healing medicine Chinese traditional research report review

Dynamics,stability,and control of a four-cable mount system for wind tunnel test

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Chinese Journal of Aeronautics 2023年第2期36卷 58-75页

作者： Zhenjun ZHAO Zhanwei ZHAO yu YAN Kaichun ZENG Xiaojun shi Han WU School of Mechanical and Materials Engineering North China University of TechnologyBeijing 100144China High Speed Aerodynamics Institute China Aerodynamics Research and Development CenterMianyang 621000China

A four-cable mount system is proposed for full-model wind tunnel flutter tests,which may adjust the pitch and roll attitude of the aircraft scaled model and ensure that the model is not subjected to cable *** system provides sufficient support to simulate the free flight of the aircraft by applying appropriate spring stiffness and cable *** proposed fourcable mount system is modeled based on Lagrange mechanics,and its dynamics equations consider aerodynamic *** singularity of the system and its bifurcation characteristics under flow conditions are analysed to determine the supercritical bifurcation phenomenon for different tension levels and distances from the front suspension point to the mass centre of the *** mathematical expressions of the longitudinal flight stability of the cable mount system are derived by linearising the system dynamics equations using small *** influence of the cable tension,spring stiffness,suspension point position,and other factors on the flight stability of the aircraft are analysed.A feedforward control algorithm is proposed to minimize the total elastic potential energy of the *** results show that the model is in the level flight state when the elastic potential energy of the four-cable mount system is minimized.A feedback control design method is proposed based on the Lyapunov stability theory to derive the closed-loop stability *** system dynamics model that includes the aircraft rigid body model,flexible cables,pulleys,springs,aerodynamic model,and servo motor control is established using the flexible multibody dynamics method.A multibody dynamics solver and Simulink are used to simulate the attitude adjustment of the model in the wind tunnel and verify the supercritical bifurcation characteristics of the system and the effectiveness of the feedback and feedforward control.

关键词： Bifurcation Cable Flight dynamics Flutter Nonlinear control systems Wind tunnels

HL-2A装置二氧化碳激光相干散射系统的研制

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核聚变与等离子体物理 2024年第2期44卷 125-132页

作者：文若楠姚可刘仪许宇鸿石中兵钟武律核工业西南物理研究院成都610041 西南交通大学聚变科学与技术研究所成都610031

在HL-2A装置上成功研制了一套CO_(2)激光相干散射诊断系统,采用了能提高系统空间分辨的切向布局以及双通道的零差式探测设计。两个通道能够同时测量等离子体芯部(ρ≈0.28)波数在10~45cm^(−1)范围中小尺度的湍流变化,其波数分辨率为±3c... 详细信息

在HL-2A装置上成功研制了一套CO_(2)激光相干散射诊断系统,采用了能提高系统空间分辨的切向布局以及双通道的零差式探测设计。两个通道能够同时测量等离子体芯部(ρ≈0.28)波数在10~45cm^(−1)范围中小尺度的湍流变化,其波数分辨率为±3cm^(−1),时间分辨率为0.5μs,能够为等离子体芯部输运研究提供重要数据。此外,由于本诊断系统采用的是主光束与本振光束同时穿过等离子体的光路设计,它还能够探测到等离子体芯部的大尺度宏观等离子体扰动。诊断信号的分析结果显示该系统可以准确地响应等离子体芯部小尺度湍流的变化,同时也能够为芯部宏观不稳定研究提供诊断数据。

关键词：激光相干散射密度扰动小尺度湍流

Improving the Mechanical Properties of Mg–Gd–Y–Ag–Zr Alloy via Pre‑Strain and Two‑Stage Ageing

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Acta Metallurgica Sinica(English Letters) 2023年第3期36卷 456-468页

作者： Baotian Du Zijian yu Kang shi Ke Liu Shubo Li Wenbo Du Faculty of Materials and Manufacturing Beijing University of Technology100 PingleyuanChaoyang DistrictBeijing 100124People’s Republic of China

In this study,we investigated the effects of single-stage ageing(SSA),two-stage ageing(TSA),2%pre-strain+single-stage ageing(P2%SSA)and 2%pre-strain-I-two-stage ageing(P2%TSA)on the mechanical properties of as-extruded Mg-8Gd-3Y-0.5Ag-0.5Zr alloy(E alloy).Compared with the SSA treatment,the TSA treatment increased the number density of/β'*** P2%SSA and P2%TSA treatments generated theγ'phase and chain-like precipitates in addition to the/β'*** contributions of these ageing treatments to the alloy strengthening can be ranked as P2%TSA>P2%SSA>TSA>SSA,because the increments in the tensile yield strength were estimated to be 199 MPa>148 MPa>144 MPa>110 ***ferent from the traditional strengthening of/β'phase in the E+SSA and E+TSA alloys,the composite precipitates comprising the/β'phase,γ'phase and chain-like precipitates in the E+P2%SSA and E+P2%TSA alloys provided better combined strengthening ***/β'phase was still dominated in the strengthening effect of the composite *** to the higher number density of/β'phase in the composite precipitates,the E+P2%TSA alloy exhibited the better mechanical performance as compared with the E+P2%SSA ***,the E+P2%TSA alloy had the ultimate tensile strength of 452 MPa,the tensile yield strength of 401 MPa and elongation to failure of 3.3%.

关键词： Magnesium alloys Rare earth Age hardening Pre-strain Mechanical properties

Synthesis and Self-assembly of a Linear Coil-Coil-Rod ABC Triblock Copolymer

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Chinese Journal of Polymer Science 2014年第11期32卷 1524-1534页

作者： Ling-ying shi yu Pan Qi-kai Zhang yu Zhou Xing-he Fan 沈志豪 Beijing National Laboratory for Molecular Sciences Key Laboratory of Polymer Chemistry and Physics of Ministry of EducationCollege of Chemistry and Molecular EngineeringPeking University College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan University

An interesting order-order transition between two different complex nanostructures was observed in a new liquid crystalline linear coil-coil-rod ABC triblock copolymer（tri BCP）. First, the ABC tri BCP, poly（dimethylsiloxane）-bpolystyrene-b-poly{2,5-bis[（4-methoxyphenyl）oxycarbonyl]styrene}（PDMS-b-PS-b-PMPCS）, was synthesized through sequential atom transfer radical polymerization. The degrees of polymerization of PDMS, PS, and PMPCS blocks are 58, 159, and 106, and the corresponding volume fractions of PDMS, PS, and PMPCS are 0.09, 0.29, and 0.62, respectively. The phase behaviors of the PDMS-b-PS diblock copolymer precursor and the final triblock copolymer were studied by smallangle X-ray scattering, one-dimensional wide-angle X-ray scattering, and transmission electron microscopy experiments. The PDMS-b-PS precursor self-assembles into hexagonally packed cylinders with a relatively small periodic size after thermal annealing. When the triblock copolymer is annealed at a relatively low temperature（120 ○C） at which the PMPCS block is in the amorphous state, the tri BCP forms core-shell hexagonally packed cylinders（CSH） with a relativly large periodic size. After the tri BCP is annealed above 140 ○C at which the PMPCS block transforms to the liquid crystalline（LC） phase, the nanophase-separated structure transforms to a three-phase four-layer lamellar structure（LAM-3P4L）. Thus, accompanied with the transition of the PMPCS blocks from the amorphous state to the LC phase, the order-order transition from CSH to LAM-3P4 L occurs in the PDMS-b-PS-b-PMPCS ABC tri BCP.

关键词： Coil-coil-rod triblock copolymer Self-assembly Order-order transition Liquid crystalline polymer Complex nanostructures.

Pathogen infection-responsive nanoplatform targeting macrophage endoplasmic reticulum for treating life-threatening systemic infection

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Nano Research 2022年第7期15卷 6243-6255页

作者： Yan Zhao Shuo Liu Zhishang shi Hangqi Zhu Mingchun Li Qilin yu Key Laboratory of Molecular Microbiology and Technology Ministry of EducationDepartment of MicrobiologyCollege of Life SciencesNankai UniversityTianjin 300071China College of Environmental Science and Engineering Tianjin Key Laboratory of Environmental Remediation and Pollution ControlNankai UniversityTianjin 300350China

Systemic infections caused by life-threatening pathogens represent one of the main factors leading to clinical *** this study,we developed a pathogen infection-responsive and macrophage endoplasmic reticulum-targeting nanoplatform to alleviate systemic *** nanoplatform is composed of large-pore mesoporous silica nanoparticles(MSNs)grafted by an endoplasmic reticulum-targeting peptide,and a pathogen infection-responsive cap containing the reactive oxygen speciescleavable boronobenzyl acid linker and bovine serum *** capped MSNs exhibited the capacity to high-efficiently load the antimicrobial peptide melittin,and to rapidly release the cargo triggered by H_(2)O_(2) or the pathogen-macrophage interaction system,but had no obvious toxicity to *** the interaction with pathogenic Candida albicans cells and macrophages,the melittin-loading nanoplatform MSNE+MEL+TPB strongly inhibited pathogen growth,survived macrophages,and suppressed endoplasmic reticulum stress together with pro-inflammatory cytokine *** a systemic infection model,the nanoplatform efficiently prevented kidney dysfunction,alleviated inflammatory symptoms,and protected the mice from *** study developed a macrophage organelle-targeting nanoplatform for treatment of life-threatening systemic infections.

关键词： mesoporous silica nanoparticle antimicrobial peptide systemic infection endoplasmic reticulum

岩溶山区小流域水库工程设计洪水计算——以WL水库工程为例

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海河水利 2024年第3期 89-91页

作者：陆建宇杜娟石宝中水北方勘测设计研究有限责任公司天津300222

为科学合理确定岩溶山区小流域水库工程设计洪水,以WL水库为研究对象,考虑坝址以上伏流区、明流区分布,按全面积法、分块叠加法分别计算设计洪水,经综合比较确定坝址推荐设计洪水过程。结果表明,分块叠加法计算的设计洪水成果与坝址下... 详细信息

为科学合理确定岩溶山区小流域水库工程设计洪水,以WL水库为研究对象,考虑坝址以上伏流区、明流区分布,按全面积法、分块叠加法分别计算设计洪水,经综合比较确定坝址推荐设计洪水过程。结果表明,分块叠加法计算的设计洪水成果与坝址下游历史洪水调查成果较接近,能反映伏流区对坝址洪水调节的实际情况,并与区域已有洪水成果协调,为该工程坝址推荐设计洪水成果。本研究成果对开展区域岩溶山区水库设计洪水计算工作有一定的借鉴意义。

关键词：岩溶山区水库工程设计洪水全面积法分块叠加法

高管贫困经历与企业内部薪酬差距缩小:自我约束效应和移情效应的共同作用

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改革 2024年第4期 126-143页

作者：魏建李世杰山东大学人文社科期刊社山东大学中泰证券金融研究院山东大学经济学院

使用2011—2021年沪深A股上市公司相关数据,探究高管贫困经历对企业内部薪酬差距的影响。研究发现,企业管理层的贫困经历能够缩小企业内部薪酬差距。机制分析表明,总经理的贫困经历可以通过“自我约束效应”降低在职消费水平,减少管理... 详细信息

使用2011—2021年沪深A股上市公司相关数据,探究高管贫困经历对企业内部薪酬差距的影响。研究发现,企业管理层的贫困经历能够缩小企业内部薪酬差距。机制分析表明,总经理的贫困经历可以通过“自我约束效应”降低在职消费水平,减少管理层薪酬;董事长贫困经历具有“移情效应”,能够提高企业职工薪酬占比,但同时董事长贫困经历也会削弱企业内部薪酬差距的激励作用,降低企业收入绩效,导致其对普通员工薪酬发挥的作用有限。对企业异质性特征的分析发现,总体而言,管理层贫困经历在非国有企业、员工议价能力较低企业、劳动密集型企业样本中发挥了更为积极的缩小企业内部薪酬差距的作用。

关键词：高管贫困经历内部薪酬差距管理层特征双重机器学习

基于氮气吸附和压汞定量表征砂岩吸水孔隙结构演化规律

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Journal of Central South University 2024年第1期31卷 182-195页

作者：孙晓明丁佳旭何林森石富坤缪澄宇张勇朱明群杨金坤谢铖 State Key Laboratory for Geomechanics Deep Underground Engineering China University of Mining and Technology-BeijingBeijing 100083China School of Mechanics and Civil Engineering China University of Mining and Technology-BeijingBeijing 100083China

为了探究水对岩石孔隙结构的作用机制,本文依托山东万福煤矿砂岩地层,针对不同浸泡时间作用下的砂岩试样,开展扫描电镜、氮气吸脱附和高压压汞联合孔隙结构测试实验,分析微孔(50 nm)的孔隙结构变化规律。结果表明:砂岩孔隙结构类型为狭... 详细信息

为了探究水对岩石孔隙结构的作用机制,本文依托山东万福煤矿砂岩地层,针对不同浸泡时间作用下的砂岩试样,开展扫描电镜、氮气吸脱附和高压压汞联合孔隙结构测试实验,分析微孔(50 nm)的孔隙结构变化规律。结果表明:砂岩孔隙结构类型为狭窄型和楔形结构,孔隙之间具有连通成缝的能力。砂岩吸水过程中孔隙度先减少后增加。微孔占比先减少后增加,介孔和大孔占比先增加后减少。根据广义分形维数和谱宽定量评估孔隙结构,得出其与孔隙质量正相关,即分维差值和谱宽越大,孔隙结构越复杂;而与岩石孔隙度呈负相关,即较大孔隙度对应较小的分维数差值和谱宽。

关键词：水岩作用砂岩孔隙结构联合表征多重分形