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湖南师范大学社会科学学报 2010年第6期39卷 39-42页

作者：吕本修山东省伦理学与精神文明建设研究基地山东济南250021

网络空间的表达自由是现代公民的一项基本权利,这一权利有效行使具有积极的道德意义,同时,这一权利的滥用也引发诸多的道德问题,因此,对网络空间的自由表达要加以限制与约束。

关键词：网络表达自由道德

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苜蓿盲蝽属昆虫个体遗传多样性比较

中国草地学报 2011年第1期33卷 117-120页

作者：吕秀华内蒙古师范大学生命科学与技术学院内蒙古呼和浩特010022

以苜蓿盲蝽属昆虫为材料,利用聚丙烯酰胺凝胶垂直板型电泳技术对苜蓿盲蝽属的7种昆虫进行了同种内不同性别和不同个体间的遗传多样性比较。结果表明：同一种群内不同的个体间具有非常明显的共性,通常具有1~2条共有酶带;同一种群内由于... 详细信息

以苜蓿盲蝽属昆虫为材料,利用聚丙烯酰胺凝胶垂直板型电泳技术对苜蓿盲蝽属的7种昆虫进行了同种内不同性别和不同个体间的遗传多样性比较。结果表明：同一种群内不同的个体间具有非常明显的共性,通常具有1~2条共有酶带;同一种群内由于个体、性别的不同,酶带的数目、颜色、宽窄稍有差异,但差异的程度远小于不同种类之间的差异。

关键词：苜蓿盲蝽遗传多样性比较

A perturbation method to the tent map based on Lyapunov exponent and its application

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Chinese Physics B 2015年第10期24卷 78-85页

作者：曹绿晨罗玉玲丘森辉刘俊秀 Guangxi Key Laboratory of Multi-source Information Mining & Security Faculty of Electronic EngineeringGuangxi Normal University School of Computing and Intelligent Systems University of Ulster

Perturbation imposed on a chaos system is an effective way to maintain its chaotic features. A novel parameter perturbation method for the tent map based on the Lyapunov exponent is proposed in this paper. The pseudo-random sequence generated by the tent map is sent to another chaos function - the Chebyshev map for the post processing. If the output value of the Chebyshev map falls into a certain range, it will be sent back to replace the parameter of the tent map. As a result, the parameter of the tent map keeps changing dynamically. The statistical analysis and experimental results prove that the disturbed tent map has a highly random distribution and achieves good cryptographic properties of a pseudo-random sequence. As a result, it weakens the phenomenon of strong correlation caused by the finite precision and effectively compensates for the digital chaos system dynamics degradation.

关键词： perturbation tent map Lyapunov exponent finite precision

Application and Practice of the Teaching Model of “Promoting Teaching by Competition” in Tourism Management Specialty

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Journal of Landscape Research 2022年第1期14卷 129-132页

作者： LI xiu lv Chen ZheNG Mingjing LI Weimei Taishan University Tai'anShandong 271000China

The fundamental task of applied universities is to cultivate high-level applied talents facing the needs of economic and social development, and "promoting teaching by competition" is the booster for the construction of applied universities and the reform of talent training mode in colleges and *** tourism management specialty as an example, the needs of subject skill competition for students’personality ability are analyzed, and the teaching mode of "promoting teaching by competition" is constructed, and the implementation of teaching process and classroom teaching design are ***, the supporting conditions of the teaching mode of "promoting teaching by competition" are put forward, such as building and perfecting the practice and training base, deepening the integration of industry and education and the cooperation of work and study, and strengthening the construction of teachers.

关键词： Promoting teaching by competition Teaching model Tourism management specialty

Copper-Catalyzed Radical Cyclization for Synthesis of 3,3-Difluoro-4-methyl-1-arylpyrrolidin-2-ones

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Copper-Catalyzed Radical Cyclization for Synthesis of 3,3-Di...

Anti-aging Effects of Alu Antisense RNA on Human Fibroblast Senescence Through the MEK-ERK Pathway Mediated by KIF15

河南省化学会2018年学术年会

作者： Wen-Peng Mai Ming-xiu lv Kui Lu School of Materials and Chemical Engineering Henan University of Engineering School of Chemical Engineering and Food Science Zhengzhou Institute of Technology

In the past five years,the fluoroalkyl radical addition over aπacceptor has become one of the most straightforward methods to construct C–CF *** advances have been achieved in this ***,compared to the prevailing C(sp)–CF formation,the incorporation of a difluoromethyl group into diverse skeletons to construct a new C(sp)–CF bond is *** the best of our knowledge,there are only very few examples on this *** instance,photoredox catalysts(Ir and Ru)were reported to promote fluoroalkylation of alkenes to render C(sp)–CF bond ***,we report Cu-catalyzed difluoroalkylation of alkenes for the construction of C(sp)–CF bond combining a cyclization for preparation of3,3-Difluoro-4-methyl-1-arylpyrrolidin-2-ones(Scheme 1).

关键词： Copper Radical cyclization Difluoromethyl group

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Current Medical Science 2023年第1期43卷 35-47页

作者： Ning JI Chong-guang WU Xiao-die WANG Zhi-xue SONG Pei-yuan WU Xin LIU Xu FENG Xiang-mei ZHANG xiu-fang WANG Zhan-jun lv Department of Genetics Hebei Medical UniversityHebei Key Lab of Laboratory AnimalShijiazhuang 050017China Research Center Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011China

Objective:To investigate whether human short interspersed nuclear element antisense RNA(Alu antisense RNA;Alu asRNA)could delay human fibroblast senescence and explore the underlying ***:We transfected Alu asRNA into senescent human fibroblasts and used cell counting kit-8(CCK-8),reactive oxygen species(ROS),and senescence-associated beta-galactosidase(SA-β-gal)staining methods to analyze the anti-aging effects of Alu asRNA on the *** also used an RNA-sequencing(RNA-seq)method to investigate the Alu asRNA-specific mechanisms of *** examined the effects of KIF15 on the anti-aging role induced by Alu *** also investigated the mechanisms underlying a KIF15-induced proliferation of senescent human ***:The CCK-8,ROS and SA-β-gal results showed that Alu asRNA could delay fibroblast ***-seq showed 183 differentially expressed genes(DEGs)in Alu asRNA transfected fibroblasts compared with fibroblasts transfected with the calcium phosphate transfection(CPT)*** KEGG analysis showed that the cell cycle pathway was significantly enriched in the DEGs in fibroblasts transfected with Alu asRNA compared with fibroblasts transfected with the CPT ***,Alu asRNA promoted the KIF15 expression and activated the MEK-ERK signaling ***:Our results suggest that Alu asRNA could promote senescent fibroblast proliferation via activation of the KIF15-mediated MEK-ERK signaling pathway.

关键词： senescent fibroblast cell proliferation Alu antisense RNA KIF15 gene expression MEK-ERK signaling pathway cell cycle

Influences of dexmedetomidine on stress responses and postoperative cognitive and coagulation functions in patients undergoing radical gastrectomy under general anesthesia

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1169-1177页

作者： Xiang-Fei Ma Shi-Jia lv Shen-Qiao Wei Bing-Rong Mao xiu-Xia Zhao Xiao-Qing Jiang Fei Zeng Xue-Ke Du Department of Anesthesiology The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530007Guangxi Zhuang Autonomous RegionChina

BACKGROUND Radical gastrectomy(RG)is commonly used in the treatment of patients with gastric cancer(GC),but this procedure may lead to stress responses,postoperative cognitive dysfunction,and blood coagulation abnormalities in *** To investigate the influences of dexmedetomidine(DEX)on stress responses and postoperative cognitive and coagulation functions in patients undergoing RG under general anesthesia(GA).METHODS One hundred and two patients undergoing RG for GC under GA from February 2020 to February 2022 were retrospectively *** these,50 patients had received conventional anesthesia intervention[control group(CG)]and 52 patients had received DEX in addition to routine anesthesia intervention[observation group(OG)].Inflammatory factor(IFs;tumor necrosis factor-α,TNF-α;interleukin-6,IL-6),stress responses(cortisol,Cor;adrenocorticotropic hormone,ACTH),cognitive function(CF;Mini-Mental State Examination,MMSE),neurological function(neuron-specific enolase,NSE;S100 calciumbinding protein B,S100B),and coagulation function(prothrombin time,PT;thromboxane B2,TXB2;fibrinogen,FIB)were compared between the two groups before surgery(T0),as well as at 6 h(T1)and 24 h(T2)after *** Compared with T0,TNF-α,IL-6,Cor,ACTH,NSE,S100B,PT,TXB2,and FIB showed a significant increase in both groups at T1 and T2,but with even lower levels in OG vs *** groups showed a significant reduction in the MMSE score at T1 and T2 compared with T0,but the MMSE score was notably higher in OG compared with *** In addition to a potent inhibitory effect on postoperative IFs and stress responses in GC patients undergoing RG under GA,DEX may also alleviate the coagulation dysfunction and improve the postoperative CF of these patients.

关键词： Dexmedetomidine Radical gastrectomy General anesthesia Inflammatory factors Stress responses

Association between mandibular posterior alveolar morphology and growth pattern in a Chinese population with normal occlusion

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2013年第1期14卷 25-32页

作者： Min HAN Rong-yang WANG Hong LIU xiu-juan ZHU Fu-lan WEI Tao lv Na-na WANG Li-hua HU Guo-ju LI Dong-xu LIU Chun-ling WANG Department of Orthodontics Shandong Provincial Key Laboratory of Oral Biomedicine Shandong University Jinan 250012 China Department of Radiology Shandong Provincial Key Laboratory of Oral Biomedicine Shandong University Jinan 250012 China

Objective:To investigate the relationship between growth patterns and mandibular posterior tooth-alveolar bone complex morphology in a Chinese population with normal ***:Forty-five patients with normal occlusion(23 males,22 females) were included in this *** these patients,20 displayed the vertical growth pattern,and 20 had the horizontal growth pattern,while the remaining patients displayed the average growth *** of the patients underwent dental cone beam computed tomography(CBCT),which included the region of the mandibular posterior teeth and the alveolar.A linear regression analysis and a correlation analysis between the facial height index(FHI) and the alveolar bone morphology were ***:The inclination of the molars,the thickness of the cortical bone,and the height of the mandibular bone differed significantly between patients with the horizontal growth pattern and those with the vertical growth pattern(Phe FHI and the inclination of the molars;the FHI and the thickness of the cortical bone;and the FHI and the height of the mandibular ***:The mandibular posterior tooth-alveolar bone complex morphology may be affected by growth patterns.

关键词： Cone beam computed tomography (CBCT) Growth pattern Alveolar morphology Normal occlusion

基于RSSI和分步粒子群算法的无线传感器网络定位算法

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控制与决策 2014年第11期29卷 1966-1972页

作者：冯秀芳吕淑芳太原理工大学计算机科学与技术学院太原030024

为了更加合理地分配网络资源、采集性能优良的信息来更好地完成任务,提高事件的定位精确度,提出一种基于接收信号强度指示(RSSI)和分步粒子群算法的无线传感器网络定位算法(IPSO-IRSSI).该算法在分析RSSI无线传播损耗模型的基础上,结合... 详细信息

为了更加合理地分配网络资源、采集性能优良的信息来更好地完成任务,提高事件的定位精确度,提出一种基于接收信号强度指示(RSSI)和分步粒子群算法的无线传感器网络定位算法(IPSO-IRSSI).该算法在分析RSSI无线传播损耗模型的基础上,结合优胜劣汰的选择思想以及目标函数最优的权重自适应方法,提出过滤锚节点机制和粒子群分步算法.仿真实验结果表明,该算法具有较高的定位精度,优于距离相关的传统定位算法.

关键词：无线传感器网络定位优化粒子群算法接收信号强度指示

Effect of erythropoietin combined with hypothermia on serum tau protein levels and neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy

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Neural Regeneration Research 2017年第10期12卷 1655-1663页

作者： Hong-yan lv Su-jing Wu Qiu-li Wang Li-hong Yang Peng-shun Ren Bao-jun Qiao Zhi-ying Wang Jia-hong Li xiu-ling Gu Lian-xiang Li Department of Neonatology Handan Maternal and Child Health Care HospitalHandanHebei ProvinceChina Department of Neonatal Pathology Handan Maternal and Child Health Care HospitalHandanHebei ProvinceChina Department of Children’s Rehabilitation Handan Maternal and Child Health Care HospitalHandanHebei ProvinceChina Department of Neural Development and Neural Pathology Hebei University of Engineering School of MedicineHandanHebei ProvinceChina

Although hypothermia therapy is effective to treat neonatal hypoxic-ischemic encephalopathy,many neonatal patients die or suffer from severe neurological *** is considered one of the most promising neuroprotective *** hypothesized that erythropoietin combined with hypothermia will improve efficacy of neonatal hypoxic-ischemic encephalopathy *** this study,41 neonates with moderate/severe hypoxic-ischemic encephalopathy were randomly divided into a control group（hypothermia alone for 72 hours,n = 20） and erythropoietin group（hypothermia ＋ erythropoietin 200 IU/kg for 10 days,n = 21）.Our results show that compared with the control group,serum tau protein levels were lower and neonatal behavioral neurological assessment scores higher in the erythropoietin group at 8 and 12 ***,neurodevelopmental outcome was similar between the two groups at 9 months of *** findings suggest that erythropoietin combined with hypothermia reduces serum tau protein levels and improves neonatal behavioral neurology outcome but does not affect long-term neurodevelopmental outcome.

关键词： nerve regeneration erythropoietin hypothermia hypoxic-ischemic encephalopathy neonate tau protein biomarkers prognosis neuroprotection neural regeneration