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Journal of Earth Science 2018年第2期29卷 408-415页

作者： xiu-juan bai Hua-Ning Qiu Wen-Gui Liu Lian-Fu Mei Key Laboratory of Tectonics and Petroleum Resources Ministry of Education China University of Geosciences State Key Laboratory of Isotope Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences

A new fully automatic ^40Ar/^39Ar laboratory with a Thermo Scientific ARGUS VI mass spectrometer has been established in China University of Geosciences （Wuhan）. We designed and developed a mini efficient preparation system （80 mL）, a CO2 laser for heating samples, a crusher for extracting fluid inclusions within K-poor minerals and an air reservoir （31 L） and pipette （0.1 mL） system. The ARGUS VI mass spectrometer is operated by the Qtegra Noble Gas software, which can control the peripheral accessories, such as pneumatic valves, CO2 laser and crusher through a PeriCon （peripheral controller）. The experimental procedures of atmospheric argon ana- lyses, ^40Ar/^39Ar dating by laser stepwise heating and by progressive crushing in vacuo, can be fully automatically performed. The weighted mean of atmospheric ^40Ar/^36Ar ratios is 302.22＋0.03 （1σ, MSWD=0.74, n=200）, indicating that air reservoir and pipette system and the whole instrument sys- tem are very stable. This laboratory is a successful pioneer example in China to establish a new no- ble gas laboratory with self-made peripheral accessories expect for the mass spectrometer.

关键词： ^40Ar/^39Ar dating fully automatic CO2 laser ARGUS VI mass spectrometer Qtegra noble gas software.

Occurrence of Excess ^40Ar in Amphibole： Implications of ^40Ar/^39Ar Dating by Laser Stepwise Heating and in vacuo Crushing

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Journal of Earth Science 2018年第2期29卷 416-426页

作者： Rong-Guo Hu xiu-juan bai Jan Wijbrans Fraukje Brouwer Yi-Lai Zhao Hua-Ning Qiu College of Earth Sciences Guangxi Key Laboratory of Hidden Metallic Ore Deposits Exploration Guilin University of Technology Guilin 541004 China Geology & Geochemistry Cluster Department of Earth Sciences VU Amsterdam De Boelelaan 1085 1081 HV Amsterdam The Netherlands Key Laboratory of Tectonics and Petroleum Resources Ministry of Education China University of Geosciences Wuhan 430074 China State Key Laboratory of Isotope Geochemistry Guangzhou Institute of Geochemistry Chinese Academy of Sciences Guangzhou 510640 China

ABSTRACT： The joint methods of ^40Ar/^39Ar laser stepwise heating and in vacuo crushing have been applied to date amphiboles from the North Qaidam ultra-high pressure metamorphic amphibolites. Two amphibole samples analyzed by laser heating yielded saddle-shaped age spectra with total gas ages of 574.5±2.5 and 562.5=±2.5 Ma. These ages are much older than the reported zircon U-Pb ages （-495 Ma） from Yuka eclogite, indicating the presence of excess ^40Ar. In order to decipher the occur- rence of excess ^40Ar and constrain the age of amphibolite-facies retrogression, two duplicate amphibole samples were further employed for ^40Ar/^39Ar in vacuo crushing analyses. Both samples exhibit similar monotonically declining release spectra, which are characterized by rapid decline of anomalously old apparent ages in the early steps. The data of the late steps yielded concordant apparent ages with pla- teau ages of 460.9±1.2 and 459.6±1.8 Ma. We interpret that gases released in the early steps derive from the significant excess ^40Ar containing secondary fluid inclusions （SFIs） due to their distribution characteristics along cracks leading to be easily extracted, whereas those released in the later steps rep- resent the contribution of the small primary fluid inclusions （PFIs）.

关键词： ^40Ar/^39Ar dating in vacuo crushing amphibole fluid inclusions.

Association between the polymorphism in class Ⅱ transactivator (CIITA) promoter Ⅳ and progressed liver diseases with chronic HBV infection

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Association between the polymorphism in class Ⅱ transactiva...

Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

中华医学会全国第九次感染病学学术会议

作者： Department of Infectious Diseases, Southwest Hospital, Chongqing (400038) Xu Qing Zhang Xiao Jun Hong Guo Hong Deng xiu juan bai Xiao Hong Wang Yu Ming Wang

The purpose of this study was to determine the frequencies of haplotypes and genotypes associated with CIITA polymorphism, and investigate their association with the risk of persistent infection and disease progression in HBV infected subjects. The polymorphism of CIITA gene promoter IV were studied in 1, 191Chinese patients with HBV infection. The polymorphisms in promoter IV (C - 1350T and G - 944C) were analyzed by sequence - specific primer polymerase chain reaction (PCR - SSP) , and four haplotypes were assigned. The frequencies of haplotypes and genotype were significantly different between persistent infected subjects and spontaneously recovered subjcts(P=.012,.001)and between progressed carriers and nonprogressed carriers(P=.002,.001).Compared with CC haplotype,the frequencies of CG and TG haplotypes were significantly decreased in persistent infected subjects(P=.020,.006),but significantly increased in progressed carriers(P=.001,.006).Compared to subjects bearing genotypes consited of non-CG haplotypes ,those bearing CC/CC homozygote or heterozygote cinsisted of CC haplotype had an increased susceptibility to persistent infection(P=.002 or .020),but a decreased susceptibility to progressed carriers(P=.001 or .007).We concluded that polymorphisms in Chinese CIITA gene promoter IV may play a role in the development of persistent HBV infection and progression of liver diseases.

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao Zhang Li Jia xiu-Jun Zhan Charity Ngina Qing-Rui Zhang Xiao-Ge Li Qi-Bao Jiang Shi bai Miao-Miao Jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

基于EDEM的花生联合收获机清选装置设计与试验

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农机化研究 2025年第1期47卷 99-105页

作者：白云李娟徐盛果青岛农业大学机电工程学院山东青岛266109 江苏深瑞光学技术有限公司南京210031

为进一步降低花生联合收获清选除杂过程中荚果损失率高、含杂率高等问题,重点研究了花生混合物(花生荚果—茎秆—土杂)基本物理参数和悬浮特性,创新提出了一种风筛组合式花生清选装置。该振动筛上筛采取锯齿式结构,下筛采取孔式结构,增... 详细信息

为进一步降低花生联合收获清选除杂过程中荚果损失率高、含杂率高等问题,重点研究了花生混合物(花生荚果—茎秆—土杂)基本物理参数和悬浮特性,创新提出了一种风筛组合式花生清选装置。该振动筛上筛采取锯齿式结构,下筛采取孔式结构,增加了花生混合物运动距离,提高了花生混合物清选效率。为确定振动筛最佳工作参数,结合EDEM仿真软件,建立了花生荚果—茎秆—土杂离散元模型,系统分析了振动筛往复作业过程中花生混合物的运动轨迹,并以振动筛振幅、频率和倾角为试验因素,以损失率和含杂率为试验指标进行试验优化分析,通过Design Expert 10试验分析软件Optimization,对试验结果进行优化。结果表明:在振动筛最佳工作参数下,即振幅为5.4 mm、频率为24 Hz、倾角为8°时,花生混合物损失率为1.57%,含杂率为1.19%。

关键词：花生清选除杂 EDEM 试验分析

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Effects of Exogenous Silicon on the Activities of Antioxidant Enzymes and Lipid Peroxidation in Chilling-Stressed Cucumber Leaves

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Agricultural Sciences in China 2009年第9期8卷 1075-1086页

作者： LIU Jiao-jing LIN Shao-hang XU Pei-lei WANG xiu-juan bai Ji-gang State Key Laboratory of Crop Biology/College of Life Sciences Shandong Agricultural UniversityTai’an 271018P.R.China

In order to increase vegetable productivity by improving environmental conditions, this article investigates the effects of exogenous silicon on the activities of major antioxidant enzymes and on lipid peroxidation under chilling stress, and it examines whether silicon-induced chilling tolerance is mediated by an increase in antioxidant activity. Cucumis sativus cv. Jinchun 4 was hydroponically cultivated to the two-leaf stage, at which point seedlings were watered with different concentrations of silicon (0, 0.1 and 1 mmol L^-1) and separately exposed to normal (25/18℃) or chilling (15/8℃) temperatures for six days under low light (100μmol m^-2 s^-9. Data were collected from the second leaves on the percentage of withering and the levels of endogenous silicon, malondialdehyde (MDA), hydrogen peroxide (H202), superoxide radical (O2^.-), superoxide dismutase (SOD, EC 1.***.1.1), glutathione peroxidase (GSH-Px, EC 1.***.1.9), ascorbate peroxidase (APX, EC 1.***.1.11), monodehydroascorbate reductase (MDHAR, EC 1.***.5.4), glutathione reductase (GR, EC 1.***.4.2), reduced glutathione (GSH) and ascorbate (AsA). Compared to normal temperatures, chilling resulted in partially withered leaves and increased MDA content. When 0.1 or 1 mmol L^-1 exogenous silicon was combined with chilling, the withering of the cucumber leaves was reduced relative to the original chilling treatment, while the endogenous silicon content was increased, antioxidants such as SOD, GSH-Px, APX, MDHAR, GR, GSH, and AsA were more active, and the levels of H2O2, O2^.-, and MDA were lower. We propose that exogenous silicon leads to greater deposition of endogenous silicon and thereby increases antioxidant activities and reduces lipid peroxidation induced by chilling.

关键词： antioxidant enzyme chilling Cucumis sativus lipid peroxidation silicon

Fast FOCUSS method based on bi-conjugate gradient and its application to space-time clutter spectrum estimation

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Science China(Information Sciences) 2017年第8期60卷 163-175页

作者： Gatai bai Ran TAO juan ZHAO Xia bai Yue WANG School of Mathematics and Statistics Beijing Institute of Technology Beijing Key Laboratory of Fractional Signals and Systems School of Information and Electronics Beijing Institute of Technology

The focal underdetermined system solver(FOCUSS) is a powerful tool for sparse representation in complex underdetermined systems. This paper presents the fast FOCUSS method based on the bi-conjugate gradient(BICG), termed BICG-FOCUSS, to speed up the convergence rate of the original FOCUSS. BICGFOCUSS was specifically designed to reduce the computational complexity of FOCUSS by solving a complex linear equation using the BICG method according to the rank of the weight matrix in FOCUSS. Experimental results show that BICG-FOCUSS is more efficient in terms of computational time than FOCUSS without losing accuracy. Since FOCUSS is an efficient tool for estimating the space-time clutter spectrum in sparse recoverybased space-time adaptive processing(SR-STAP), we propose BICG-FOCUSS to achieve a fast estimation of the space-time clutter spectrum in mono-static array radar and in the mountaintop system. The high performance of the proposed BICG-FOCUSS in the application is demonstrated with both simulated and real data.

关键词： focal underdetermined system solver(FOCUSS) sparse recovery(SR) bi-conjugate gradient(BICG) space-time adaptive processing(STAP) space-time clutter spectrum

Predicting CircRNA-Disease Associations Based on Improved Weighted Biased Meta-Structure

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Journal of Computer Science & Technology 2021年第2期36卷 288-298页

作者： xiu-juan Lei Chen Bian Yi Pan School of Computer Science Shaanxi Normal UniversityXi'an 710119China School of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Department of Computer Science Georgia State UniversityAtlantaGA 30302U.S.A

Circular RNAs(circRNAs)are RNAs with a special closed loop structure,which play important roles in tumors and other *** to the time consumption of biological experiments,computational methods for predicting associations between circRNAs and diseases become a better *** the limited number of verified circRNA-disease associations into account,we propose a method named CDWBMS,which integrates a small number of verified circRNA-disease associations with a plenty of circRNA information to discover the novel circRNA-disease *** adopts an improved weighted biased meta-structure search algorithm on a heterogeneous network to predict associations between circRNAs and *** terms of leave-one-out-cross-validation(LOOCV),10-fold cross-validation and 5-fold cross-validation,CDWBMS yields the area under the receiver operating characteristic curve(AUC)values of 0.9216,0.9172 and 0.9005,***,case studies show that CDWBMS can predict unknow circRNA-disease *** conclusion,CDWBMS is an effective method for exploring disease-related circRNAs.

关键词： circular RNA(circRNA) circRNA-disease association meta-structure heterogeneous network

New deghosting method based on generalized triangulation

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Journal of Systems Engineering and Electronics 2009年第3期20卷 504-511页

作者： bai Jing Wang Guohong xiu Jianjuan Wang Xiaobo Inst. of Information Fusion Naval Aeronautical and Astronautical Univ. Yantai 264001 P. R. China

A new deghosting method based on the generalized triangulation is presented. First, two intersection points corresponding to the emitter position are obtained by utilizing two azimuth angles and two elevation angles from two jammed 3-D radars （or 2-D passive sensors）. Then, hypothesis testing based deghosting method in the multiple target scenarios is proposed using the two intersection points. In order to analyze the performance of the proposed method, the correct association probability of the true targets and the incorrect association probability of the ghost targets are defined. Finally, the Monte Carlo simulations are given for the proposed method compared with the hinge angle method in the cases of both two and three radars. The simulation results show that the proposed method has better performance than the hinge angle method in three radars case.

关键词： deghosting generalized triangulation hinge angle distributed radar network hypothesis testing

Synthesis and Anti-inflammatory Action of (η-C_5H_5)_2Ti(Sal)_2 and (η-C_5H_5)_2Ti(Clo)_2

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Chemical Research in Chinese Universities 2006年第1期22卷 6-10页

作者： LI xiu-juan ZENG Zheng-zhi College of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000 P. R. China

Two new complexes （Cp）2Ti （Sal）2 and（Cp）2Ti（Clo）2 （Cp=Cyclopentadienyl η^5-C5H5 ）, have been synthesized in anhydrous THF by the reaction of HSal（o-hydroxybenzoic acid, salicylate acid） or HClo[N-（ m-chloro-phenyl） anthranili acid, acidum clofenamicum] with （Cp）2TiCl2 and characterized by means of elemental analyses, IR, H NMR, ^13C NMR, UV and molar conductivity. In complex （Cp）2Ti（Sal）2 or（Cp）2Ti（Clo）2, the oxygen atom of the carboxyl group coordinates to Ti（Ⅳ） in a monodentate manner. The inhibitory action of the complexes on mouse ear tumefaction caused by croton oil and rat foot granulation growth caused by cotton balls is higher than that of the corresponding ligands HSal, HClo and [ （Cp）2TiCl2 ], whereas their toxicity is lower than those of the free ligands.

关键词： Salicylate acid N-(m-Chlorophenyl) anthranilic acid Cyclopentadienyltitanium complexes Anti-in-flammatory