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Progress of shrink polymer micro- and nanomanufacturing

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Microsystems & Nanoengineering 2021年第6期7卷 1-23页

作者： Wenzheng He xiongying ye Tianhong Cui State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentsTsinghua UniversityBeijing 100084China Department of Mechanical Engineering University of Minnesota111 Church Street S.E.MinneapolisMN 55455USA

Traditional lithography plays a significant role in the fabrication of micro-and ***,the fabrication process still suffers from the limitations of manufacturing devices with a high aspect ratio or threedimensional *** findings have revealed that shrink polymers attain a certain potential in micro-and nanostructure *** technique,denoted as heat-induced shrink lithography,exhibits inherent merits,including an improved fabrication resolution by shrinking,controllable shrinkage behavior,and surface wrinkles,and an efficient fabrication *** merits unfold new avenues,compensating for the shortcomings of traditional *** using shrink polymers is investigated in regard to its mechanism and *** review classifies typical applications of shrink polymers in micro-and nanostructures into the size-contraction feature and surface ***,corresponding shrinkage mechanisms and models for shrinkage,and wrinkle parameter control are *** the size-contraction feature,this paper summarizes the progress on highaspect-ratio devices,microchannels,self-folding structures,optical antenna arrays,and *** surface wrinkles,this paper evaluates the development of wearable sensors,electrochemical sensors,energy-conversion technology,cell-alignment structures,and antibacterial ***,the limitations and prospects of shrink lithography are analyzed.

关键词： nanowires shrink limitations

Recent Progress of Biomarker Detection Sensors

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Research 2020年第1期2020卷 1429-1454页

作者： Ruitao Liu xiongying ye Tianhong Cui State Key Lab Precise Measurement Technology&Instrument Department of Precision InstrumentsTsinghua UniversityBeijingChina Department of Mechanical Engineering University of MinnesotaMinneapolisMinnesotaUSA

Early cancer diagnosis and treatment are crucial research fields of human *** method that has proven efficient is biomarker detection which can provide real-time and accurate biological information for early *** review presents several biomarker sensors based on electrochemistry,surface plasmon resonance(SPR),nanowires,other nanostructures,and,most recently,metamaterials which have also shown their mechanisms and prospects in application in recent *** with previous reviews,electrochemistry-based biomarker sensors have been classified into three strategies according to their optimizing methods in this *** makes it more convenient for researchers to find a specific fabrication method to improve the performance of their *** that,as microfabrication technologies have improved and novel materials are explored,some novel biomarker sensors—such as nanowire-based and metamaterial-based biomarker sensors—have also been investigated and summarized in this review,which can exhibit ultrahigh resolution,sensitivity,and limit of detection(LoD)in a more complex detection *** purpose of this review is to understand the present by reviewing the *** can break through bottlenecks of existing biomarker sensors by reviewing previous works and finally meet the various complex detection needs for the early diagnosis of human cancer.

关键词： diagnosis summarized finally

Theoretical analysis and simulation of thermoelastic deformation of bimorph microbeams

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Science China(Technological Sciences) 2013年第7期56卷 1715-1722页

作者： SHANG YuanFang ye xiongying FENG JinYang State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instruments and MechanologyTsinghua University

In this paper, a purely mechanical model for the thermoelastic behavior of a bimorph microbeam is presented. The thermoelastic coupling problem of the microbeam is converted to a mechanical problem by simply replacing the thermal stress in the beam with a bulk force and a surface force. Thermoelastic deformation of the bimorph microbeams with constraints frequently used in micro-electro-mechanical systems (MEMS) devices has been derived based on this model and is characterized by FEA simulation. Coincidence of the results from theory and simulation demonstrates the validity of the model. The analysis shows that a bimorph microbeam with a soft constraint and a uniform temperature field has a larger thermoelastic deformation than that with a hard constraint and a linear temperature field. In addition to the adoption of materials with large CTE mismatch,thickness ratio and length ratio of the two layers need to be optimized to get a large thermoelastic deformation.

关键词： mechanical model thermoelastic deformation microbeams bimorph

On-chip fast mixing by a rotary peristaltic micropump with a single structural layer

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Science China(Technological Sciences) 2013年第4期56卷 1047-1054页

作者： DU Min MA ZengShuai ye xiongying ZHOU ZhaoYing State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instruments and MechanologyTsinghua University

In this work,a rotary pump based micromixer for on-chip rapid mixing and liquid transportation is demonstrated and *** pumping and mixing are realized using a microfluidic chip with a single structural polydimethylsiloxane layer and a portable electric control *** rotary pump consists of an annular channel and is driven by a motor and *** flow field caused by the peristaltic movement of the channel membrane of the rotary pump is simulated and *** statistically calculating and comparing the normalized standard deviations of the flow velocity components in a microchannel,it is revealed that up-and-down mixing is the fastest,followed by segment mixing and parallel *** mixing styles,segment mixing and parallel mixing,were experimentally demonstrated using the *** pump achieved 90% of the mixing index in 1 s for the segment mixing *** for the parallel mixing type,the mixing index was up to 90% after 5 s,which is more than 100-fold improvement compared to conventional mixing by interfacial *** mixing speeds in both directions were improved prominently by increasing the rotational speed of the pump.

关键词： microfluidic mixing rotary pump magnetic driving

Multi-dimensionally ordered, multi-functionally integrated r-GO@TiO2（B）@Mn304 yolk-membranc shell superstructures for ultrafast lithium storage

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Nano Research 2016年第7期9卷 2057-2069页

作者： Long Pan Yitao Liu Xuming Xie xiongying ye Xiaodong Zhu Key Laboratory of Advanced Materials (MOE) Department of Chemical Engineering Tsinghua University Beijing 100084 China State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instrument Tsinghua University Beijing 100084 China Academy of Fundamental and In terdisciplinary Sciences Harbin Institute of Technology Harbin 150080 China

TiO2（B） is an attractive new anode candidate for lithium-ion batteries （LIBs） due to its unique and highly desirable properties, including high structural integrity, long cycle life, and low cost. However, despite these merits, its inherent slow lithium and electron transport kinetics hinder its practical application to LIBs. Here, we propose a novel, simple route towards multi-dimensionally ordered, multi-functionally integrated reduced graphene oxide （r-GO）@TiO2（B）@Mn304 yolk-membrane-shell superstructures in which r-GO nanosheets, TiO2（B） nanosheets, and Mn304 nanoparticles are hierarchically organized to achieve remarkable synergistic interactions. This hybridization design is fundamentally bilateral in nature, aiming to overcome the conductivity and capacity deficiencies of TiO2（B） simultaneously. The resulting r-GO@TiO2（B）@Mn304 yolk-membrane- shell superstructures have great potential as advanced anode materials for ultrafast lithium storage, delivering a strikingly high reversible capacity of 662 mA.h-g-1 at 500 mA-g^-1 after 500 charge-discharge cycles.

关键词： yolk-membrane-shellsuperstructure TiO2(B) Mn3O4 reduced graphene oxide lithium-ion battery

On-chip circulating tumor cells isolation based on membrane filtration and immuno-magnetic bead clump capture

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Nanotechnology and Precision Engineering 2022年第1期5卷 24-34页

作者： Shuai Zhang Yue Wang Chaoqiang Yang Junwen Zhu xiongying ye Wenhui Wang State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision InstrumentsTsinghua UniversityBeijing 100084China

Isolating rare circulating tumor cells(CTCs)from blood is critical for the downstream analysis that is important in cancer-related research,diagnosis,and medicine,and efforts are ongoing to increase the efficiency and purity of CTC isolation in *** in this paper is a two-stage integrated microfluidic chip for coarse-to-fine CTC isolation from whole ***,blood cells are removed by filtration using a micropore-array membrane,then CTCs and other cells that are trapped in the micropores are peeled off the membrane by a novel release method based on air–liquid interfacial tension,which significantly increases the recovery rate of *** second stage is CTC capture based on an on-chip dense immuno-magnetic-bead clump,which offers high capture efficiency and *** the micropore filtration and immuno-magnetic-bead capture are validated and optimized ***,the integrated microfluidic chip can realize a recovery rate of 85.5%and a purity of 37.8%for rare cancer cells spiked in whole blood.

关键词： Circulating tumor cells Whole blood Isolation Filtration Magnetic-bead clump

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不同种源米槠苗期生长差异及早期选择

广西林业科学 2024年第4期53卷 469-473页

作者：徐梦阳林昌勇徐文元潘昕昊叶雄英李婷吴南生孙荣喜江西农业大学林学院亚热带森林资源培育江西省重点实验室江西南昌330045 广丰区铜拔山生态林场江西上饶334000 江西交通职业技术学院江西南昌330013

为给米槠(Castanopsis carlesii)优良种源选择提供参考,以12个种源米槠幼苗为研究材料,分析不同种源米槠幼苗生长差异,对种子性状(千粒重及可溶性糖和淀粉含量)和幼苗生长指标进行相关性分析,结合聚类分析和隶属函数分析,选择早期速生... 详细信息

为给米槠(Castanopsis carlesii)优良种源选择提供参考,以12个种源米槠幼苗为研究材料,分析不同种源米槠幼苗生长差异,对种子性状(千粒重及可溶性糖和淀粉含量)和幼苗生长指标进行相关性分析,结合聚类分析和隶属函数分析,选择早期速生种源。结果表明,不同种源米槠幼苗苗高和地径均差异极显著;苗高和地径变异系数均较高,其均值分别为22.8%和17.0%。可溶性糖含量与苗高呈极显著正相关,与地径呈显著正相关,可采用种子可溶性糖含量作为种源早期选择的补充指标。结合聚类分析和隶属函数分析,初步筛选出江西定南(JXDN)、福建华安(FJHA)和安徽祁门(AHQM)3个速生优良种源。

关键词：生长种子性状种源早期选择米槠

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基于两轴红外地平仪的全范围角度测量方法

清华大学学报（自然科学版） 2008年第8期48卷 1290-1293页

作者：蔡瑜叶雄英朱荣周兆英清华大学精密仪器与机械学系北京100084

姿态测量是飞行器实现自主导航的前提条件。针对单轴红外地平仪在飞行器姿态绝对测量中存在盲区的问题,提出了利用两轴红外地平仪进行全范围角度测量方案。在待测姿态角平面内,将地平仪两轴垂直放置,通过判断转动过程中两组传感器所在... 详细信息

姿态测量是飞行器实现自主导航的前提条件。针对单轴红外地平仪在飞行器姿态绝对测量中存在盲区的问题,提出了利用两轴红外地平仪进行全范围角度测量方案。在待测姿态角平面内,将地平仪两轴垂直放置,通过判断转动过程中两组传感器所在的象限位置,利用两轴必有一轴工作在非盲区的特点,合理选取输出量进行转角解算。解算结果和实验设定转角进行比较,二者静态偏差小于1°,能实现360°全范围角度测量。两轴红外地平仪全范围角度测量克服了单轴红外地平仪角度测量范围的局限性,对飞行控制中姿态角反馈具有重要意义。

关键词：红外地平仪飞行器姿态测量盲区

定向多壁碳纳米管薄膜及其场致发射距离敏感特性

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清华大学学报（自然科学版） 2006年第11期46卷 1876-1879页

作者：郭琳瑞叶雄英周兆英梁吉清华大学精密仪器与机械学系北京100084 清华大学机械工程系北京100084

研究了定向生长的多壁碳纳米管薄膜场致发射的距离敏感特性,以改进现有场发射传感器中硅及金属针尖的性能。化学气相沉积方法制备的多壁碳纳米管薄膜表现出良好的尖端放电特性,其开启电场可至1.42 V/μm,阈值电场可至2.22 V/μm,通过计... 详细信息

研究了定向生长的多壁碳纳米管薄膜场致发射的距离敏感特性,以改进现有场发射传感器中硅及金属针尖的性能。化学气相沉积方法制备的多壁碳纳米管薄膜表现出良好的尖端放电特性,其开启电场可至1.42 V/μm,阈值电场可至2.22 V/μm,通过计算得到的尖端电场增强因子可至4 034以上。随着发射间距的增加,场致发射电流非线性地降低,发射电流对发射间距的最大变化率为0.018 8μA/μm。通过拟合分析发现,场致发射电流随发射间距的变化基本符合Fow ler-N ordhe im关系,该特性可作为碳纳米管场致发射传感器的基本原理用于位移的检测。

关键词：微机电系统传感器场致发射碳纳米管