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Sleep Quality and Emotional Adaptation among Freshmen in Elite Chinese Universities during Prolonged COVID-19 Lockdown:The Mediating Role of Anxiety Symptoms

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International Journal of Mental Health Promotion 2024年第2期26卷 105-116页

作者： Xinqiao Liu Linxin zhang xinran zhang School of Education Tianjin UniversityTianjin300350China

Under the effects of COVID-19 and a number of ongoing lockdown tactics,anxiety symptoms and poor sleep quality have become common mental health issues among college freshmen and are intimately related to their emotional adaptation.To explore this connection,this study gathered data from a sample of 256 freshmen enrolled in an elite university in China in September 2022.The association between sleep quality,anxiety symptoms,and emotional adaptation was clarified using correlation analysis.Additionally,the mediating function of anxiety symptoms between sleep quality and emotional adaptation was investigated using a structural equation model.The results reveal that:(1)Chinese elite university freshmen who were subjected to prolonged lockdown had poor sleep quality and mild anxiety symptoms;(2)a significant positive correlation between poor sleep quality and anxiety symptoms was identified;(3)anxiety symptoms were found to have a significant negative impact on emotional adaptation;(4)poor sleep quality had a negative impact on emotional adaptation through anxiety symptoms.This research makes a valuable contribution by offering insights into the intricate relationship between sleep quality and emotional adaptation among freshmen in elite Chinese universities during prolonged lockdown conditions,and it is beneficial for schools and educators to further improve school schedules and psychological health initiatives.

关键词： COVID-19 pandemic sleep quality emotional adaptation anxiety symptoms lockdown freshmen

Across two phylogeographic breaks: Quaternary evolutionary history of a mountain aspen (Populus rotundifolia) in the Hengduan Mountains

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Plant Diversity 2024年第3期46卷 321-332页

作者： Jieshi Tang Xiaoyan Fan Richard I.Milne Heng Yang Wenjing Tao xinran zhang Mengyun Guo Jialiang Li Kangshan Mao Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education College of Life SciencesState Key Laboratory of Hydraulics and Mountain River EngineeringSichuan UniversityChengdu 610065PR China Institute of Molecular Plant Sciences University of EdinburghEdinburgh EH93JHUK School of Ecology and Environment Tibet UniversityLhasa 850000PR China

Biogeographical barriers to gene flow are central to plant phylogeography.In East Asia,plant distribution is greatly influenced by two phylogeographic breaks,the Mekong-Salween Divide and Tanaka-Kaiyong Line,however,few studies have investigated how these barriers affect the genetic diversity of species that are distributed across both.Here we used 14 microsatellite loci and four chloroplast DNA fragments to examine genetic diversity and distribution patterns of 49 populations of Populus rotundifolia,a species that spans both the Mekong-Salween Divide and the Tanaka-Kaiyong Line in southwestern China.Demographic and migration hypotheses were tested using coalescent-based approaches.Limited historical gene flow was observed between the western and eastern groups of P.rotundifolia,but substantial flow occurred across both the Mekong-Salween Divide and Tanaka-Kaiyong Line,manifesting in clear admixture and high genetic diversity in the central group.Wind-borne pollen and seeds may have facilitated the dispersal of P.rotundifolia following prevalent northwest winds in the spring.We also found that the Hengduan Mountains,where multiple genetic barriers were detected,acted on the whole as a barrier between the western and eastern groups of P.rotundifolia.Ecological niche modeling suggested that P.rotundifolia has undergone range expansion since the last glacial maximum,and demographic reconstruction indicated an earlier population expansion around 600 Ka.The phylogeographic pattern of P.rotundifolia reflects the interplay of biological traits,wind patterns,barriers,niche differentiation,and Quaternary climate history.This study emphasizes the need for multiple lines of evidence in understanding the Quaternary evolution of plants in topographically complex areas.

关键词： Chloroplast DNA Microsatellite Phylogeographic break Populus rotundifolia Quaternary history Wind direction

Mo-doped one-dimensional needle-like Ni_(3)S_(2) as bifunctional electrocatalyst for efficient alkaline hydrogen evolution and overall-water-splitting

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ChemPhysMater

ChemPhysMater 2024年第1期3卷 74-82页

作者： Junjie Huang Yupeng Xing Jinzhao Huang Fei Li Gang Zhao Xingmin Yu Binxun Li xinran zhang School of Physics and Technology University of JinanJinan 250022China

Hydrogen energy plays an important role in clean energy system and is considered the core energy source for future technological development owing to its lightweight nature,high calorific value,and clean combustion products.The electrocatalytic conversion of water into hydrogen is considered a highly promising method.An electrocatalyst is indispensable in the electrocatalytic process,and finding an efficient electrocatalyst is essential.However,the current commercial electrocatalysts(such as Pt/C and Ru)are expensive;therefore,there is a need to find an inexpensive and efficient electrocatalyst with high stability,corrosion resistance,and high electrocatalytic efficiency.In this study,we developed a cost-effective bifunctional electrocatalyst by incorporating molybdenum into nickel sulfide(Ni_(3)S_(2))and subsequently tailoring its structure to achieve a one-dimensional(1D)needle-like configuration.The hydrogen production efficiency of nickel sulfide was improved by changing the ratio of Mo doping.By analyzing the electrochemical performance of different Mo-doped catalysts,we found that the Ni_(3)S_(2)-Mo-0.1 electrocatalyst exhibited the best electrocatalytic effect in 1 M KOH;at a current density of 10 mA cm^(-2),it exhibited overpotentials of 120 and 279 mV for hydrogen evolution reaction(HER)and oxygen evolution reaction(OER),respectively;at a higher current density of 100 mA cm^(-2),the HER and OER overpotentials were 396 and 495 mV,respectively.Furthermore,this electrocatalyst can be used in a two-electrode water-splitting system.Finally,we thoroughly investigated the mechanism of the overall water splitting of this electrocatalyst,providing valuable insights for future hydrogen production via overall-water-splitting.

关键词： Hydrogen evolution reaction Molybdenum doped Nickel sulfide Overall water splitting Needle-like multistage structure

ACBP4-WRKY70-RAP2.12 module positively regulates submergence-induced hypoxia response in Arabidopsis thaliana

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Journal of Integrative Plant Biology 2024年第6期66卷 1052-1067页

作者： Mengyun Guo Yingjun Yao Kangqun Yin Luna Tan Meng Liu Jing Hou Han zhang Ruyun Liang xinran zhang Heng Yang Xiaoxiao Chen Jinrui Tan Yan Song Shangling Lou Liyang Chen Xuejing Liu Si Tang Yongqi Hu Jin Yan Wensen Fu Kai Yang Ruijia zhang Xuerui Li Yao Liu Zhen Yan Wei Liu Yu Han Jianquan Liu Kangshan Mao Huanhuan Liu Key Laboratory for Bio-resources and Eco-environment & State Key Lab of Hydraulics & Mountain River Engineering Sichuan Zoige Alpine Wetland Ecosystem National Observation and Research Station Key Laboratory for Bio-resource and Eco-environment of Ministry of Education College of Life Sciences Sichuan University

ACYL-CoA-BINDING PROTEINs(ACBPs) play crucial regulatory roles during plant response to hypoxia, but their molecular mechanisms remain poorly understood. Our study reveals that ACBP4 serves as a positive regulator of the plant hypoxia response by interacting with WRKY70,influencing its nucleocytoplasmic shuttling in Arabidopsis thaliana. Furthermore, we demonstrate the direct binding of WRKY70 to the ACBP4 promoter, resulting in its upregulation and suggesting a positive feedback loop. Additionally, we pinpointed a phosphorylation site at Ser638 of ACBP4, which enhances submergence tolerance, potentially by facilitating WRKY70's nuclear shuttling. Surprisingly, a natural variation in this phosphorylation site of ACBP4 allowed A.thaliana to adapt to humid conditions during its historical demographic expansion. We further observed that both phosphorylated ACBP4 and oleoyl-Co A can impede the interaction between ACBP4 and WRKY70, thus promoting WRKY70's nuclear translocation. Finally, we found that the overexpression of orthologous Bna C5.ACBP4and Bna A7.WRKY70 in Brassica napus increases submergence tolerance, indicating their functional similarity across genera. In summary, our research not only sheds light on the functional significance of the ACBP4 gene in hypoxia response, but also underscores its potential utility in breeding flooding-tolerant oilseed rape varieties.

关键词： ACBP4 Arabidopsis thaliana humid adaptation natural variation RAP2.12 WRKY70

U1 small nuclear ribonucleoprotein is essential for early larval development in silkworm, Bombyx mori

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Insect Science 2022年第2期29卷 379-387页

作者： Xiaoqian zhang Dehong Yang Xu Yang xinran zhang Yong zhang Yongping Huang Shengxiang zhang Zulian Liu College Forestry Shangdong Agriculture UniversityShangdong ProvinceTaianChina Key Laboratory of Insect Developmental and Evolutionary Biology Center for Excellence in Molecular Plant SciencesShanghai Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghaiChina CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijingChina Soochow University SuzhouJiangsu ProvinceChina

U1 small nuclear ribonucleoproteins(U1 snRNP)associates with 5ʹsplice sites in the form of ribonucleoprotein particles and is highly conserved among species.The physiological functions of U1 snRNP in a lepidopteran model insect Bombyx mori is mostly unknown.Here,we showed that U1 snRNP plays an important role in the development of silkworm.Knockout of U1 snRNP in silkworm showed either delayed or stationary 1st instar larva development compared with the wild-type group.U1 snRNP deletion mutants exhibited abnormal cellular phenotypes with enlarged cell nucleus,scant cytoplasm and enlarged nuclei.RNA-seq analysis revealed that genes involved in metabolic pathway,biosynthesis of secondary metabolites and steroid hormone biosynthesis were significantly affected by U1 snRNP depletion.Taken together,our study suggests that U1 snRNP homeostasis plays an important role in silkworm development.

关键词： CRISPR/Cas9 development ecdysone silkworm U1 snRNP

Nitrogen rejection from low quality natural gas by pressure swing adsorption experiments and simulation using dynamic adsorption isotherms

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Chinese Journal of Chemical Engineering 2022年第2期35卷 120-129页

作者： xinran zhang Hua Shang Jiangfeng Yang Libo Li Jinping Li Research Institute of Special Chemicals College of Chemistry and Chemical EngineeringTaiyuan University of TechnologyTaiyuan 030024China Shanxi Key Laboratory of Gas Energy Efficient and Clean Utilization Taiyuan 030024China

In order to remove N_(2) from low quality natural gas,a mathematical model has been established by Aspen adsorption,using the CH_(4)-selective sorbent silicalite-1 pellets.The dynamic adsorption isotherm was first simulated by breakthrough simulation of a CH_(4)/N_(2) mixture at different adsorption pressures and feed flow rates based on breakthrough experiments.The resulting simulated CH_(4) dynamic adsorption amounts were very close to the experimental data at three different adsorption pressures(100,200,and 300 kPa).Moreover,a single-bed,three-step pressure swing adsorption(PSA)experiment was performed,and the results were in good agreement with the simulated data,further corroborating the accuracy of the gas dynamic adsorption isotherm obtained by the simulation method.Finally,based on the simulated dynamic adsorption isotherm of CH_(4) and N_(2),a four-bed,eight-step PSA process has been designed,which enriched 75%(vol)CH_(4) and 80%(vol)CH_(4) to 95%(vol)and 99%(vol),and provided 99%(vol)recovery.

关键词： Natural gas Silicalite-1 Simulation Dynamic adsorption Pressure swing adsorption process

Synergistic cytotoxicity of binary combinations of inorganic and organic disinfection byproducts assessed by real-time cell analysis

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Journal of Environmental Sciences 2022年第7期34卷 222-231页

作者： Mengge Fan Longfei Shu xinran zhang Miao Yu Yongting Du Junlang Qiu Xin Yang Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology School of Environmental Science and EngineeringSun Yat-sen UniversityGuangzhou 510006China

Chlorine, chlorine dioxide, and ozone are widely used as disinfectants in drinking water treatments. However, the combined use of different disinfectants can result in the formation of various organic and inorganic disinfection byproducts(DBPs). The toxic interactions, including synergism, addition, and antagonism, among the complex DBPs are still unclear. In this study, we established and verified a real-time cell analysis(RTCA) method for cytotoxicity measurement on Chinese hamster ovary(CHO) cell. Using this convenient and accurate method, we assessed the cytotoxicity of a series of binary combinations consisting of one of the 3 inorganic DBPs(chlorite, chlorate, and bromate) and one of the 32 regulated and emerging organic DBPs. The combination index(CI) of each combination was calculated and evaluated by isobolographic analysis to reflect the toxic interactions. The results confirmed the synergistic effect on cytotoxicity in the binary combinations consisting of chlorite and one of the 5 organic DBPs(2 iodinated DBPs(I-DBPs) and 3 brominated DBPs(Br-DBPs)), chlorate and one of the 4 organic DBPs(3 aromatic DBPs and dibromoacetonitrile), and bromate and one of the 3 organic DBPs(2 I-DBPs and dibromoacetic acid). The possible synergism mechanism of organic DBPs on the inorganic ones may be attributed to the influence of organic DBPs on cell membrane and cell antioxidant system. This study revealed the toxic interactions among organic and inorganic DBPs, and emphasized the latent adverse outcomes in the combined use of different disinfectants.

关键词： Disinfection byproducts(DBPs) Real-time cell analysis(RTCA) Synergistic cytotoxicity

Epidemiological characteristics of pulmonary tuberculosis in patients with pneumoconiosis based on its social determinants and risk factors in China:a cross-sectional study from 27 provinces

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Chinese Medical Journal 2022年第24期135卷 2984-2997页

作者： Huanqiang Wang Huaping Dai Jiayu He Xiangpei Lyu xinran zhang Tao Li Department of Occupational Respiratory Disease National Institute for Occupational Health and Poison ControlChinese Center for Disease Control and PreventionBeijing 100050China National Center for Respiratory Medicine National Clinical Research Center for Respiratory DiseasesInstitute of Respiratory MedicineChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100029China Department of Pulmonary and Critical Care Medicine Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China Department of Clinical Research and Data Management Center of Respiratory MedicineChina-Japan Friendship HospitalBeijing 100029China

Background:Patients with pneumoconiosis have an elevated risk of contracting pulmonary tuberculosis(PTB)and need particular attention.However,extensive population-based studies on the prevalence of PTB in patients with pneumoconiosis have not been reported in China since 1992.This study aimed to investigate the epidemiological characteristics of PTB in patients with pneumoconiosis based on its social determinants and risk factors in China.Methods:Based on the Commission on Social Determinants of Health(CSDH)framework,data were obtained from a questionnaire survey of patients with pneumoconiosis from China’s 27 provinces(autonomous regions,municipalities)from December 2017 to June 2021.By chi-square and multivariate logistic regression analyses,the epidemiological characteristics of PTB in the patients were identified based on its prevalence and odds ratio(OR)and associated social determinants and risk factors.The population attributable fractions(PAFs)of significant risk factors were also calculated.Results:The prevalence of PTB in patients with pneumoconiosis(n=10,137)was 7.5%(95%confidence interval[CI]:7.0-8.0%).Multivariate logistic regression analysis showed that risk factors included in-hospital exposure to patients with PTB(OR=3.30,95%CI:2.77-3.93),clinically diagnosed cases(OR=3.25,95%CI:2.42-4.34),and northeastern regions(OR=2.41,95%CI:1.76-3.31).In addition,lack of work-related injury insurance(WRII),being born in a rural area,being unemployed,living in western regions,household exposure to patients with PTB,smoking,being underweight,complications of pulmonary bullae or pneumothorax,hospitalization history,and former drinkers among the rural patients were also statistically significant risk factors.Being born in a rural area,lack of WRII and in-hospital exposure to patients with PTB had higher PAFs,which were 13.2%(95%CI:7.9-18.5%),12.5%(95%CI:8.3-16.7%),and 11.6%(95%CI:8.8-14.3%),respectively.Conclusion:The prevalence of PTB in pneumoconiosis remains high in China;it is basically in line with the CSDH m

关键词： Pulmonary tuberculosis Pneumoconiosis Social determinants Risk factors

Identifiability Analysis of Load Model Parameters by Estimating Confidential Intervals

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CSEE Journal of Power and Energy Systems 2023年第5期9卷 1666-1675页

作者： xinran zhang Chao Lu Ying Wang Qiantu Ruan Hongbo Ye Weihong Wang the School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China. the State Key Laboratory of Control and Simulation of Power System and Generation Equipment Tsinghua UniversityBeijing 100084China School of Technology Beijing Forestry UniversityBeijing 100083China the State Grid Shanghai Electric Power Company Shanghai 200122China

The identification of load model parameters from practical measurement data has become an essential method to build load models for power system simulation,analysis and control.In practical situations,the accuracy of the load model parameters identification results is impacted by data quality and measurement accuracy,which leads to the problem of identifiability.In this paper,an identifiability analysis methodology of load model parameters,by estimating the confidential intervals(CIs)of the parameters,is proposed.The load model structure and the combined optimization and regression method to identify the parameters are first introduced.Then,the definition and analysis method of identifiability are discussed.The CIs of the parameters are estimated through the profile likelihood method,based on which a practical identifiability index(PII)is defined to quantitatively evaluate identifiability.Finally,the effectiveness of the proposed analysis approach is validated by the case study results in a practical provincial power grid.The results show that the impact of various disturbance magnitudes,measurement errors and data length can all be reflected by the proposed PII.Furthermore,the proposed PII can provide guidance in data length selection in practical load model identification situations.

关键词： Confidential interval Load modeling parameter estimation practical identifiability