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超声引导锁骨上神经与颈浅丛联合肌间沟臂丛阻滞用于锁骨手术的临床观察

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新疆医学 2018年第1期48卷 33-35页

作者：郑德军黄新利王艳梅史海涛孙志超焉耆县人民医院麻醉科新疆焉耆841100 廊坊市人民医院麻醉科河北廊坊065000

目的观察超声引导下锁骨上神经与颈浅丛联合肌间沟臂丛神经阻滞的效果和并发症发生情况。方法将60例择期行锁骨手术的病人随机分为A、B、C 3组,每组20例,均选用0.25%罗哌卡因共30 mL在超声引导下实施神经阻滞。A组:肌间沟臂丛阻滞(注药3... 详细信息

目的观察超声引导下锁骨上神经与颈浅丛联合肌间沟臂丛神经阻滞的效果和并发症发生情况。方法将60例择期行锁骨手术的病人随机分为A、B、C 3组,每组20例,均选用0.25%罗哌卡因共30 mL在超声引导下实施神经阻滞。A组:肌间沟臂丛阻滞(注药30 mL);B组:颈浅丛阻滞(注药10 mL)+肌间沟臂丛阻滞(注药20 mL);C组:锁骨上神经阻滞(注药10 mL)+肌间沟臂丛阻滞(注药20 mL)。麻醉实施后,记录患者的生命体征,锁骨上神经、颈浅丛、臂丛神经所支配颈肩区域感觉阻滞(针刺法)起效时间和完善时间、镇痛持续时间、VAS评分和并发症发生情况。结果B、C组感觉阻滞起效、完善时间较A组缩短(P<0.05)。B、C组镇痛持续时间与A组相比延长(P<0.05)。B、C组术中VAS评分较A组更低(P<0.05)。C组阻滞后并发症的发生率、镇痛药的使用率低于A、B组(P<0.05)。结论超声引导下10 mL 0.25%罗哌卡因锁骨上神经阻滞联合20 mL0.25%罗哌卡因肌间沟臂丛神经阻滞用于锁骨手术,起效迅速、镇痛时间长、并发症少。

关键词：超声颈浅丛神经阻滞肌间沟臂丛神经阻滞锁骨上神经阻滞锁骨手术

基于GDAL的高分L1A级影像轮廓图的自动建立

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矿山测量 2019年第3期47卷 50-53,57页

作者：李晓青丁礼江陈文平黄新利弓小平新疆大学地质与矿业工程学院新疆乌鲁木齐830049 新疆地质矿产勘查开发局第一区域地质调查大队新疆乌鲁木齐830013 新疆维吾尔自治区卫星应用工程中心新疆乌鲁木齐830000

高分数据在各个领域使用越来越广泛,自动获取高分L1A级影像的轮廓图变得日益迫切。无法自动获取影像轮廓图给数据管理造成的种种不便,本文描述了利用GDAL库和其它第三方类库在. NET平台上自动生成高分L1A级影像轮廓图的过程,包括自动查... 详细信息

高分数据在各个领域使用越来越广泛,自动获取高分L1A级影像的轮廓图变得日益迫切。无法自动获取影像轮廓图给数据管理造成的种种不便,本文描述了利用GDAL库和其它第三方类库在. NET平台上自动生成高分L1A级影像轮廓图的过程,包括自动查找、解压、读取元数据、创建影像轮廓图。实现了影像轮廓的可视化,方便了高分影像数据的管理。实验表明该方法简单、可行。

关键词： GDAL 影像轮廓自动解压高分 Tar包

赴老挝援助开展新型冠状病毒肺炎防控的实践与思考

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中华灾害救援医学 2021年第5期9卷 994-997页

作者：邬志薇黄兴黎刘晓强孙艳红李多云南省疾病预防控制中心云南昆明650022 云南省卫生健康委员会

目的总结援助老挝开展新型冠状病毒肺炎(Corona Virus Disease 2019,COVID-19)疫情防控实践的做法和经验,探讨进一步做好卫生援外工作的关键环节。方法对中国抗疫医疗专家组赴老挝援助开展COVID-19疫情防控开展的主要工作和取得的成效... 详细信息

目的总结援助老挝开展新型冠状病毒肺炎(Corona Virus Disease 2019,COVID-19)疫情防控实践的做法和经验,探讨进一步做好卫生援外工作的关键环节。方法对中国抗疫医疗专家组赴老挝援助开展COVID-19疫情防控开展的主要工作和取得的成效进行回顾性分析。结果此次卫生援外行动出发前做好充分准备,专家组到达后与老方建立了有效沟通合作机制,通过推进核酸检测能力提升、协助完善防控指南、打造示范定点收治医院、开展专业人员培训等方式,协助老方有效开展COVID-19疫情防控。结论此次援助老挝开展COVID-19疫情防控实践经验对今后的卫生援外工作有一定的指导意义。

关键词：老挝公共卫生援助实践新型冠状病毒肺炎

The RAG key to vertebrate adaptive immunity descended directly from a bacterial ancestor

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National Science Review 2022年第8期9卷 18-21页

作者： Xin Tao Ziwen huang Fan Chen xinli Wang Tingting Zheng Shaochun Yuan Anlong Xu State Key Laboratory of Biocontrol Guangdong Key Laboratory of Pharmaceutical Functional GenesSouthern Marine Science and Engineering Guangdong Laboratory (Zhuhai)School of Life SciencesSun Yat-sen University Center for Infection and Immunity School of MedicineSun Yat-sen University Shanghai Institute of Immunology College of Basic Medical SciencesShanghai Jiao Tong University School of Medicine Laboratory for Marine Biology and Biotechnology Qingdao National Laboratory for Marine Science and Technology School of Life Sciences Beijing University of Chinese Medicine

The emergence of RAG recombinase to mediate V(D)J recombination has been considered an important milestone in the evolution of adaptive immunity in jawed vertebrates. In past decades,hypotheses, including the invasion of viral or bacterial genes and the transposition of mobile elements, have been proposed to shed light on the origin and evolution of the RAG genes and V(D)J recombination.

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A Constitutive Model of Granite Shear Creep under Moisture

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Journal of Earth Science 2016年第4期27卷 677-685页

作者： Xingang Wang Bin Hu Huiming Tang xinli Hu Jiading Wang Lei huang State Key Laboratory of Continental Dynamics Department of Geology Northwest University Faculty of Engineering China University of Geosciences

Previous constitutive models of granite shear creep have two limitations：（1） although moisture greatly affects granite shear creep behavior, currently there are no constitutive models that include this factor;（2） there are also no models that include an acceleration stage. This paper presents an improved Burgers constitutive model with the addition of a damage parameter to characterize the moisture effect and uses a nonlinear relation equation between stress and strain for inclusion as the acceleration stage. The damage parameter is determined from granite creep experiment under four different moisture contents（0%, 0.22%, 0.49%, and 0.79%）. The nonlinear relation equation is obtained by fitting a dataset of stain versus time under five different loading stages. To verify the presented model, a creep experiment was conducted on other granite samples and the results show that the model agrees well with the experimental observation data.

关键词： moisture state shear creep constitutive model Burgers model damage variable,nonlinear visco-elasto-plastic three-dimensional creep constitutive equation.

基于人工神经网络的水厂建设项目造价估算方法

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净水技术 2020年第9期39卷 158-162,175页

作者：王祺周律马可可孙傅陈宇敏徐艺星黄新丽清华大学环境学院北京100084 成都环境投资集团有限公司四川成都610041

对于城镇自来水厂建设项目,项目前期准确的造价估算是项目能够发挥预期效益的保证。由于项目前期缺少详细的设计文件,同时涉及多种复杂且不确定的因素,且造价与各因素间的关系并不固定,在进行水厂项目造价估算时,大多需要依赖历史项目... 详细信息

对于城镇自来水厂建设项目,项目前期准确的造价估算是项目能够发挥预期效益的保证。由于项目前期缺少详细的设计文件,同时涉及多种复杂且不确定的因素,且造价与各因素间的关系并不固定,在进行水厂项目造价估算时,大多需要依赖历史项目样本数据的建模方法。文中主要基于实际自来水厂建设项目工程造价数据,分析筛选出18个与工程造价相关的影响因素作为输入变量,分别借助人工神经网络中的BP和RBF算法,通过对人工神经网络模型的校验和对比,发现2种模型对训练样本数据都具有很好的拟合性。研究表明,BP神经网络模型具有更好的预测能力,所有测试样本的估算精度可以控制在±30%以内,达到了项目建议书阶段的估算精度要求。

关键词：自来水厂造价模型人工神经网络 BP 算法 RBF 算法

Gold nanoparticles doped metal-organic frameworks as near-infrared light-enhanced cascade nanozyme against hypoxic tumors

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Nano Research 2020年第3期13卷 653-660页

作者： xinli Liu Yongchun Pan Jingjing Yang Yanfeng Gao Ting huang Xiaowei Luan Yuzhen Wang Yujun Song Department of Biomedical Engineering and Jiangsu Key Laboratory of Artificial Functional Materials College of Engineering and Applied SciencesNanjing UniversityNanjing210093China Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(IAM) Jiangsu National Synergistic Innovation Center for Advanced Materials(SICAM)Nanjing Tech UniversityNanjing211816China

We report gold nanoparticles(AuNPs)doped iron-based metal-organic frameworks(GIM)which displays near-infrared light(NIR)-enhanced cascade nanozyme against hypoxic *** to the strong protein adsorption-induced surface passivation,AuNPs suffer from the loss of glucose oxidase(GOx)***,GIM could protect the GOx-like activity of AuNPs with the satisfactory shield *** addition,GIM exhibited excellent photothermal conversion ability and unique NIR light-enhanced GOx-like activity,which could efficiently increase the endogenous H2O2 ***,as the produced H2O2 is converted by GIM into O2 and highly toxic ***,GIM-catalyzed cascade reactions with NIR light irradiation not only offer the O2 but also promote the reactive oxygen species(ROS)generation at tumor *** produced O2 could be further applied to AuNPs catalytic oxidation of glucose and relieve hypoxic condition of tumor microenvironment(TME).As a proof-of-concept study,GIM demonstrates the admirable tumor ablation under NIR irradiation in vivo.

关键词： nanozyme metal-organic frameworks gold nanoparticles near-infrared light reactive oxygen species

小鼠胚胎脊髓Draxin蛋白表达水平的动态变化研究

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神经解剖学杂志 2019年第2期35卷 122-126页

作者：赵吉倩陈文勇柏芳娟边康达贾崇黄新莉赵禄禄杨佳宁苏玉红河北医科大学人体解剖学教研室石家庄050000 河北医科大学病理生理教研室石家庄050000

目的:探讨正常小鼠胚胎脊髓不同发育时期背侧抑制性轴突导向蛋白(Draxin)的表达部位和表达水平的动态变化过程。方法:应用免疫组织化学、Western Blot观察不同发育阶段胎鼠脊髓内Draxin的分布及表达变化特点;应用体外培养结合免疫荧光... 详细信息

目的:探讨正常小鼠胚胎脊髓不同发育时期背侧抑制性轴突导向蛋白(Draxin)的表达部位和表达水平的动态变化过程。方法:应用免疫组织化学、Western Blot观察不同发育阶段胎鼠脊髓内Draxin的分布及表达变化特点;应用体外培养结合免疫荧光双染标记,观察不同类型神经细胞内Draxin的表达情况。结果:免疫组织化学染色结果显示,不同发育时期胎鼠脊髓内部及其周边组织内,Draxin的表达呈现明显的动态变化趋势; Western Blot检测结果显示,E11. 5开始Draxin表达量逐渐增加,至E14. 5达到高峰,此后下降并逐渐消失;体外培养结合免疫荧光双标的结果显示,部分Tuj-1阳性的未成熟神经元、Nestin阳性的神经干细胞以及GFAP阳性的星形胶质细胞均表达Draxin。结论:Draxin在胎鼠脊髓发育过程中的表达,具有明显的动态变化趋势,多种类型的神经元和星形胶质细胞表达Draxin。

关键词：背侧抑制性轴突导向蛋白脊髓神经嵴免疫组织化学小鼠

Influence of pulse polarity on electron emission property of antiferroelectric ceramic

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Chinese Science Bulletin 2008年第12期53卷 1789-1795页

作者： SHENG ZhaoXuan FENG YuJun CUI Jie huang Xuan XU Zhuo SUN xinli Electronic Materials Research Laboratory Xi'an Jiaotong University Xi'an 710049 China 103 Teaching and Researching Laboratory the Second Artillery Engineering Institute Xi'an 710025 China

The electron emission property of a novel antiferroelectric cathode material lanthanum-doped lead zirconate stannate titanate (PLZST) on the application of positive or negative triggering voltage pulses has been investigated. All experiments were performed in a vacuum of 10^(-5) Torr and at room tempera-ture. It was discovered that there were two electron emission pulses when low positive triggering voltage was applied to the rear electrode, and three electron emission pulses when high positive trig-gering voltage was applied. However there were always two electron emission pulses when negative triggering pulses were applied. This phenomenon is proposed to be a result of both field electron emission at triple junctions and electron emission caused by polarization reversal. The experimental observations indicate that domain movement in the vicinity close to the triple junction under applica-tion of the triggering voltage pulse may be a primary origin of electron emission from PLZST.

关键词：脉冲技术极性电子发射反铁电陶瓷