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激光轰击金属液面溅射过程的数值模拟

力学学报 2024年第1期56卷 285-297页

作者：张兴权刘航轩段士伟裴善报左立生张晖安徽工业大学先进金属材料绿色制备与表面技术教育部重点实验室安徽马鞍山243002 安徽工业大学机械工程学院安徽马鞍山243002

目前,极紫外光被认为是制备特征尺寸小于7 nm芯片所必备的光源,激光轰击液态金属锡靶是其产生的主要方式之一.采用体积分数(volurne of fluid,VOF)方法建立了激光轰击金属锡液面产生溅射的模型,并对液料溅射和雾化的演化过程进行了数值... 详细信息

目前,极紫外光被认为是制备特征尺寸小于7 nm芯片所必备的光源,激光轰击液态金属锡靶是其产生的主要方式之一.采用体积分数(volurne of fluid,VOF)方法建立了激光轰击金属锡液面产生溅射的模型,并对液料溅射和雾化的演化过程进行了数值模拟,研究了冠状水花的产生机制以及雾化时的流场变化.在此基础上,进一步研究了金属液态锡在不同的能量、光斑直径和脉宽的激光轰击下溅射产生的冠的宽度和高度随时间演化情况.研究表明:在激光辐照产生的高压等离子体的高速冲击下,液膜经历快速运动、冠状射流和雾化3个阶段,液膜生长主要原因是惯性力作用;液膜上下两端存在较大的速度梯度是射流形状发生变化的主要原因;冠边缘处雾化现象的产生是由Rayleigh-Taylor和Plateau-Rayleigh不稳定性共同作用的结果.在激光轰击下,冠的高度和宽度随激光能量增加而增大,但随着时间推移,冠宽和冠高的增长速率逐渐减小;激光光斑和脉宽对冠宽及冠高的影响较为复杂,在前期影响较小,在后期冠宽及冠高随它们数值增加而减小.

关键词：激光高压等离子体溅射雾化数值模拟

Anti-retroviral drugs: current state and development in the next decade

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Acta Pharmaceutica Sinica B 2018年第2期8卷 131-136页

作者： xingquan zhang Division of Infectious Diseases Department of Medicine School of Medicine University of CaliforniaSan Diego

The pace of discovery of new antiretroviral(ARV) drugs has slowed, although the efficacy and safety of once-daily fixed dose combinations have been extensively investigated. Several traditional ARV drugs remain in phase Ⅲ clinical trials. This review summarizes current information on ARV drugs in phase Ⅲ clinical trials and focuses on the development of ARV drugs in the next decade.

关键词： Antiretroviral drugs Long-acting formulations Attachment inhibitors Maturation inhibitors Nanomedicine

Direct anti-HCV agents

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Acta Pharmaceutica Sinica B 2016年第1期6卷 26-31页

作者： xingquan zhang Division of Infectious Diseases University of CaliforniaSan Diego School of Medicine

Unlike human immunodeficiency virus(HIV)and hepatitis B virus(HBV),hepatitis C virus(HCV)infection is a curable *** direct antiviral agent(DAA)targets are focused on HCV NS3/4A protein(protease),NS5 B protein(polymerase)and NS5 A *** first generation of DAAs includes boceprevir and telaprevir,which are protease inhibitors and were approved for clinical use *** cure rate for genotype 1 patients increased from 45% to 70% when boceprevir or telaprevir was added to standard PEG-IFN/*** effective and less toxic second generation DAAs supplanted these drugs by *** second generation of DAAs includes sofosbuvir(Sovaldi),simeprevir(Olysio),and fixed combination medicines Harvoni and Viekira *** drugs increase cure rates to over 90%without the need for interferon and effectively treat all HCV *** these drugs the "cure HCV"goal has become a *** remain about drug resistance mutations and the high cost of these *** investigation of new HCV drugs is progressing rapidly;fixed dose combination medicines in phase III clinical trials include Viekirax,asunaprevirtdaclatasvirtbeclabuvir,grazoprevirtelbasvir and others.

关键词： Hepatitis C virus Cure HCV Sustained virologic response Direct antiviral agents NS3/4A protease inhibitor

SIMULATION OF CYLINDRICAL UPSETTING OF POROUS MATERIALS BY FINITE ELEMENT METHOD

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中国有色金属学会会刊：英文版 1998年第1期8卷 25-28,142页

作者： zhang, xingquan Peng, Yinghong Ruan, Xueyu Li, Miaoquan Wu, Shichun Shanghai Jiao Tong Univ Shanghai China

ＳＩＭＵＬＡＴＩＯＮＯＦＣＹＬＩＮＤＲＩＣＡＬＵＰＳＥＴＴＩＮＧＯＦＰＯＲＯＵＳＭＡＴＥＲＩＡＬＳＢＹＦＩＮＩＴＥＥＬＥＭＥＮＴＭＥＴＨＯＤ①ＺｈａｎｇＸｉｎｇｑｕａｎ，ＰｅｎｇＹｉｎｇｈｏｎｇａｎｄＲｕａｎＸｕｅｙ... 详细信息

ＳＩＭＵＬＡＴＩＯＮＯＦＣＹＬＩＮＤＲＩＣＡＬＵＰＳＥＴＴＩＮＧＯＦＰＯＲＯＵＳＭＡＴＥＲＩＡＬＳＢＹＦＩＮＩＴＥＥＬＥＭＥＮＴＭＥＴＨＯＤ①ＺｈａｎｇＸｉｎｇｑｕａｎ，ＰｅｎｇＹｉｎｇｈｏｎｇａｎｄＲｕａｎＸｕｅｙｕＮａｔｉｏｎａｌＤｉｅ＆Ｍｏｌｄ...

关键词： porous metal materials the critical technological parameters defects

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高产气井生产管柱非线性流致振动实验研究

实验技术与管理 2024年第3期41卷 45-53页

作者：闫新江张晓彤陈西国于继飞张兴全黄辉毛良杰中海油研究总院有限责任公司北京100028 中海石油(中国)有限公司天津分公司天津300450 西南石油大学石油与天然气工程学院四川成都610500

三高气井生产管柱在高速流体冲击下容易发生剧烈振动,但目前关于此类流致振动的研究大多集中于理论模型和一些小型室内实验阶段。油气井生产管柱具有其独特性,超大的细长比决定了管柱的整体刚度极低,一般的小型实验系统很难模拟出这样... 详细信息

三高气井生产管柱在高速流体冲击下容易发生剧烈振动,但目前关于此类流致振动的研究大多集中于理论模型和一些小型室内实验阶段。油气井生产管柱具有其独特性,超大的细长比决定了管柱的整体刚度极低,一般的小型实验系统很难模拟出这样的特点。该研究建立了一个大型生产管柱实验台架,用PE管模拟了一个具有超大细长比特征的油管柱模型,用以模拟生产管柱在高速流体冲击下的振动特性。实验结果表明:三高气井生产管柱在高速流体作用下会以某一固定频率发生振动,振动时管柱中间和底部位置的振幅最大;气体产量越大,管柱振动越剧烈;增加油管壁厚可以有效抑制油管的振动幅度,但不可以改变管柱的振动频率;封隔器安装位置过高或过低都不能起到较好的抑制振动的效果,单个封隔器安装在管柱8/10位置可以起到较好的抑制振动的效果。

关键词：可变载荷三高气井流致振动生产管柱

Analysis of the Lost Circulation Problem

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Fluid Dynamics & Materials Processing 2023年第6期19卷 1721-1733页

作者： xingquan zhang Renjun Xie Kuan Liu Yating Li Yuqiang Xu CNOOC Research Institute Beijing100101China College of Petroleum Engineering China University of PetroleumQingdao266580China

The well-known“lost circulation”problem refers to the uncontrolled flow of whole mud into a *** order to address the problem related to the paucity of available data,in the present study,a model is introduced for the lost-circulation risk sample profile of a drilled *** model is built taking into account effective data(the Block L).Then,using a three-dimensional geological modeling software,relying on the variation function and sequential Gaussian simulation method,a three-dimensional block lost-circulation risk model is introduced able to provide relevant information for regional analyses.

关键词： Geostatistics risk assessment variation function sequential gaussian simulation drilling risk lost circulation evaluation method

Analysis of the Applicability of a Risk Quantitative Evaluation Method to High Temperature-Pressure Drilling Engineering

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Fluid Dynamics & Materials Processing 2023年第6期19卷 1385-1395页

作者： Renjun Xie xingquan zhang Baolun He Ningyu Zheng Yuqiang Xu CNOOC Research Institute Beijing100101China College of Petroleum Engineering China University of PetroleumQingdao266580China

The optimization of methods for the quantitative evaluation of risks in drilling engineering is an effective means to ensure safety in situations where high temperature and high pressure blocks are *** such a context,this study analyzes the complexity of the drilled wells in such *** is shown that phenomena such as well kick,loss,circulation,and sticking,are related to the imbalance of wellbore pressure.A method for risk quantitative evaluation is proposed *** method is used to evaluate the risk for 9 drilled *** comparing the predictions of the method with actual historical data related to these wells,it is found that the coincidence rate is about 95%.

关键词： Risk assessment applicability formation pressure

Pickering乳液自组装CL-20/n-Al/F2605复合空心微球的制备与性能

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爆破器材 2024年第4期53卷 9-16页

作者：孙鹏瞻杨敏尢淇高登钊李聪颖张行泉郭长平西北工业大学伦敦玛丽女王大学工程学院陕西西安710129 西南科技大学四川省新型含能材料军民融合创新中心四川绵阳621010 山西北化关铝化工有限公司山西永济044500

高能量、高爆热的六硝基六氮杂异伍兹烷(CL-20)/Al复合物由于自身的高感度而限制了在炸药领域的广泛应用。为制备高能量和高安全性的CL-20/Al含能复合材料,采用Pickering乳液法制备了空心球形CL-20/n-Al/F2605(氟橡胶)复合物,并对Picker... 详细信息

高能量、高爆热的六硝基六氮杂异伍兹烷(CL-20)/Al复合物由于自身的高感度而限制了在炸药领域的广泛应用。为制备高能量和高安全性的CL-20/Al含能复合材料,采用Pickering乳液法制备了空心球形CL-20/n-Al/F2605(氟橡胶)复合物,并对Pickering乳液稳定性、复合物表面结构、热分解、燃烧及安全性能进行了分析。结果显示:当2 mL乙酸乙酯中溶解的CL-20固体质量为0.10~0.14 g、油水质量比在1:5~1:7之间、超声时间小于30 min、静置时间小于120 min时,形成的乳液稳定性好。该复合物表面结构粗糙,中位径d_(50)为73.17μm,各组分复合均匀。复合物的热分解峰温和活化能分别为236.7℃、164.6 kJ/mol,n-Al和F2605降低了CL-20分解过程中21.2%的活化能。复合物平均线性燃速为7.14 cm/s;特性落高H_(50)为39.5 cm,和原料CL-20相比提升了26.5 cm,安全性能得到提高。

关键词：六硝基六氮杂异伍兹烷(CL-20) 纳米铝粉(n-Al) 微球 Pickering乳液

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Experimental Research on Laser Shot Peening to Form Aluminum Alloy

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武汉理工大学学报 2006年第S3期28卷 837-840页

作者： zhang xingquan zhang Yongkang GU Yongyu ZHOU Jianzhong YANG Chaojun School of Mechanical Engineering,Jiangsu University,Zhenjiang 212013,China, School of Mechanical Engineering Jiangsu UniversityZhenjiang 212013China

Laser shot peening forming is a novel technology,which employs residual stress induced by intense laser to shape precisely the *** this paper,the aeronautic aluminum alloy LY12CZ was selected as an object to research experimentally the magnitude of deformation versus numbers of laser shot peening,and surface quality in laser shot zone was also *** specimen was impacted along its centerline by the high-power,short-duration pulses *** experimental results show that the arc height and hardness becomes greater with numbers of shot peening increasing and eventually arrives to saturated state,and sur- face roughness after laser shot peening decreases slightly and dislocation density increases greatly,which indicates that the laser shot peening is a technique combining laser shock processing and metal forming.

关键词： laser shot peening deformation hardness roughness microstructure