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MAGNETIC PROPERTIES OF Nd_2(Fe_(1-x)M_x)_(14)B(M=C,Si)ALLOYS

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Acta Metallurgica Sinica(English Letters) 1989年第8期2卷 122-126页

作者： xing Feng jiang chao HE Wenwang Department of Physics,Peking University,Beijing,China [Originally published in ACTA METALL SIN (CHINESEEDN) 24 (5) 1988pp B348—B352,received 22 October 1986:in revised form 8 May 1987]

The magnetic properties of Nd_2(Fe_(1-x)M_x)_(14)B(M=C and Si) compounds have been investi- *** Fe by small amount of metalloid C and Si atoms,the compounds are in tetragonal structure and have uniaxial *** substitution of C for part of Fe de- creases the Curie temperature of the compounds and the intrinsic coercivity of bond samples at low *** replacement of Fe by Si makes the Curie temperature increase with a maximum at the vicinity of x=*** the range of the content of Si is 0≤x≤0.10,the coercivity distinctly increases at room *** 62.7 kA/m at x=0 to 138.7kA/m at x=0.06,where the residual magnetization has a maximum:in the mean time the saturation magnetization decreases only by a small amount.

关键词： Nd-Fe-B alloy magnetic properties Curie temperature

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

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Neural Regeneration Research 2025年第9期20卷 2655-2666页

作者： Yiyang Qin Wenzhen Zhu Tingting Guo Yiran Zhang Tingting xing Peng Yin Shihua Li Xiao-jiang Li Su Yang Guangdong Key Laboratory of Non-human Primate Research Key Laboratory of CNS Regeneration(Ministry of Education)Guangdong–HongKong–Macao Institute of CNS RegenerationJinan UniversityGuangzhouGuangdong ProvinceChina

Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene,which encodes a ligand-dependent transcription facto *** mutant androgen receptor protein,characterized by polyglutamine expansion,is prone to misfolding and forms aggregates in both the nucleus and cytoplasm in the brain in spinal and bulbar muscular atrophy *** aggregates alter protein-protein interactions and compromise transcriptional *** this study,we reported that in both cultured N2a cells and mouse brain,mutant androgen receptor with polyglutamine expansion causes reduced expression of mesencephalic astrocyte-de rived neurotrophic *** n of mesencephalic astrocyte-derived neurotrophic factor amelio rated the neurotoxicity of mutant androgen receptor through the inhibition of mutant androgen receptor *** down endogenous mesencephalic astrocyte-derived neurotrophic factor in the mouse brain exacerbated neuronal damage and mutant androgen receptor *** findings suggest that inhibition of mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor is a potential mechanism underlying neurodegeneration in spinal and bulbar muscular atrophy.

关键词： androgen receptor mesencephalic astrocyte-derived neurotrophic factor mouse model neurodegeneration neuronal loss neurotrophic factor polyglutamine disease protein misfolding spinal and bulbar muscular atrophy transcription factor

Impacts of the annual cycle of background SST in the tropical Pacific on the phase and amplitude of ENSO

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 12-17页

作者： Song jiang Congwen Zhu Ning jiang State Key Laboratory of Severe Weather(LASW) Chinese Academy of Meteorological SciencesBeijingChina College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijingChina

The dominant annual cycle of sea surface temperature(SST)in the tropical Pacific exhibits an antisymmetric mode,which explains 83.4%total variance,and serves as a background of El Niño-Southern Oscillation(ENSO).However,there is no consensus yet on its anomalous impacts on the phase and amplitude of *** on data during 1982-2022,results show that anomalies of the antisymmetric mode can affect the evolution of ENSO on the interannual scale via Bjerknes feedback,in which the positive(negative)phase of the antisymmetric mode can strengthen El Niño(La Niña)in boreal winter via an earlier(delayed)seasonal cycle transition and larger(smaller)annual *** magnitude of the SST anomalies in the equatorial eastern Pacific can reach more than±0.3◦C,regulated by the changes in the antisymmetric mode based on random sensitivity *** reveal the spatial pattern of the annual cycle associated with the seasonal phase-locking of ENSO evolution and provide new insight into the impact of the annual cycle of background SST on ENSO,which possibly carries important implications for forecasting ENSO.

关键词： Annual cycle SST anomaly Antisymmetric mode ENSO

计算机硬件设备的运维决策和评估数学模型分析

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计算机科学 2018年第B06期45卷 568-572,579页

作者：翟永刘津陈杰刘磊邢绪超杜江国家基础地理信息中心北京100830

结合计算机硬件设备运维的实际情况,基于设备/子系统可靠度和可用性理论,按照运维资金效益最优化的原则,分析了设备/子系统的资产残值、业务重要度和不可靠度等运维重要度变量的测算方法。在此基础上,研究并构建了计算机硬件设备/子系... 详细信息

结合计算机硬件设备运维的实际情况,基于设备/子系统可靠度和可用性理论,按照运维资金效益最优化的原则,分析了设备/子系统的资产残值、业务重要度和不可靠度等运维重要度变量的测算方法。在此基础上,研究并构建了计算机硬件设备/子系统运维重要度评估数学模型,并据此提出了运维决策算法。最后,采用计算机设备/子系统可靠度理论及基于马尔可夫链的可用性分析,结合实例提出了运维效益的评估量化方法,这对计算机设备运维效益的量化考核有一定的启发作用。

关键词：可靠度可用性设备资产残值业务重要度运维重要度评估运维决策效益评估

Toward understanding the role of genomic repeat elements in neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 646-659页

作者： Zhengyu An Aidi jiang Jingqi Chen Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence Fudan UniversityShanghaiChina Zhangjiang Fudan International Innovation Center ShanghaiChina

Neurodegenerative diseases cause great medical and economic burdens for both patients and society;however, the complex molecular mechanisms thereof are not yet well understood. With the development of high-coverage sequencing technology, researchers have started to notice that genomic repeat regions, previously neglected in search of disease culprits, are active contributors to multiple neurodegenerative diseases. In this review, we describe the association between repeat element variants and multiple degenerative diseases through genome-wide association studies and targeted sequencing. We discuss the identification of disease-relevant repeat element variants, further powered by the advancement of long-read sequencing technologies and their related tools, and summarize recent findings in the molecular mechanisms of repeat element variants in brain degeneration, such as those causing transcriptional silencing or RNA-mediated gain of toxic function. Furthermore, we describe how in silico predictions using innovative computational models, such as deep learning language models, could enhance and accelerate our understanding of the functional impact of repeat element variants. Finally, we discuss future directions to advance current findings for a better understanding of neurodegenerative diseases and the clinical applications of genomic repeat elements.

关键词： Alzheimer's disease ataxia deep learning long-read sequencing neurodegeneration neurodegenerative diseases Parkinson's disease repeat element structural variant

A kinetic study and factor analysis of solar thermochemical membrane reactors for syngas production

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Science China Technological Sciences 2025年第1期 207-221页

作者： Jiaxin xing chao XU Xiangyu SUN Xin XIA Fei JIN Qiongqiong jiang Jiale GAO Key Laboratory of Power Station Energy Transfer Conversion and System of MOE School of Energy Power and Mechanical EngineeringNorth China Electric Power University Department of Chemistry University College London School of Chemistry and Chemical Engineering Ningxia Key Laboratory of Solar Chemical Conversion TechnologyState Ethnic Affairs CommissionNorth Minzu University

Solar thermochemical conversion technologies are promising for effectively utilizing solar energy by capturing the full spectrum of solar radiation. To overcome the challenges of low energy conversion efficiency and intermittency faced by solar thermochemical conversion, these technologies can be effectively integrated with membrane reactor technology. Although the performance of solar thermochemical membrane reactors has been experimentally tested, the chemical reactions and oxygen transport mechanisms during the energy conversion process remain poorly understood. This study introduces a resistance network model to elucidate the interactions between interfacial reactions and bulk diffusion during simultaneous oxidationreduction reactions on both sides of the membrane. We analyzed the oxygen flux of the membrane reactor under various operating conditions using this model to identify the reaction/transport-limiting side of the overall process. The most effective solar membrane reactor configuration utilizes natural gas and CO2, facilitating clean conversion of fossil fuels with significant advantages in fuel production and energy efficiency. Introducing CH4lowers the overall reaction temperature, maintains low oxygen partial pressure on the sweep side, and produces a synthesis gas with a 2:1 H2/CO molar ratio. Finally, a sensitivity analysis was used to explore the relationship between overall fuel production performance and operational parameters,highlighting the critical role of this research in enhancing the reaction and transport performance of membrane reactors and advancing the development of solar-driven thermochemical fuel production technologies.

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Optimal Scheduling of an Independent Electro-Hydrogen System with Hybrid Energy Storage Using a Multi-Objective Standardization Fusion Method

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Energy Engineering 2025年第1期122卷 63-84页

作者： SuliangMa ZeqingMeng Mingxuan Chen Yuan jiang School of Electrical and Control Engineering North China University of TechnologyBeijing100144China ChinaThree Gorges Technology Co. Ltd.Beijing100032China School of Automation and Electrical Engineering University of Science and Technology BeijingBeijing100083China

In the independent electro-hydrogen system(IEHS)with hybrid energy storage(HESS),achieving optimal scheduling is ***,it presents a challenge due to the significant deviations in values ofmultiple optimization objective functions caused by their physical *** deviations seriously affect the scheduling process.A novel standardization fusion method has been established to address this issue by analyzing the variation process of each objective function’s *** optimal scheduling results of IEHS with HESS indicate that the economy and overall energy loss can be improved 2–3 times under different optimization *** proposed method better balances all optimization objective functions and reduces the impact of their *** the cost of BESS decreases by approximately 30%,its participation deepens by about 1 ***,if the price of the electrolyzer is less than 15￥/kWh or if the cost of the fuel cell drops below 4￥/kWh,their participation will increase *** study aims to provide a more reasonable approach to solving multi-objective optimization problems.

关键词： Electro-hydrogen system multi-objective optimization standardization method hybrid energy storage system

Constraints on holographic QCD phase transitions from PTA observations

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 71-78页

作者： Song He Li Li Sai Wang Shao-jiang Wang Center for Theoretical Physics and College of Physics Jilin University School of Physical Science and Technology Ningbo University Max Planck Institute for Gravitational Physics (Albert Einstein Institute) CAS Key Laboratory of Theoretical Physics Institute of Theoretical Physics Chinese Academy of Sciences School of Fundamental Physics and Mathematical Sciences Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of Sciences (UCAS) School of Physical Sciences University of Chinese Academy of Sciences (UCAS) Theoretical Physics Division Institute of High Energy Physics Chinese Academy of Sciences

The underlying physics of QCD phase transition in the early Universe remains largely unknown due to its strong-coupling nature during the quark-gluon plasma/hadron gas transition, yet a holographic model has been proposed to quantitatively fit the lattice QCD data while with its duration of the first-order phase transition(FoPT) left undetermined. At specific baryon chemical potential, the first-order QCD phase transition agrees with the observational constraint of baryon asymmetry. It, therefore, provides a scenario for phase transition gravitational waves(GWs) within the standard model of particle physics. If these background GWs could contribute dominantly to the recently claimed common-spectrum red noise from pulsar timing array(PTA) observations, the duration of this FoPT can be well constrained, and the associated primordial black holes are still allowed by current observations.

关键词： pulsar timing array QCD phase transition gravitational waves primordial black holes

Offload Strategy for Edge Computing in Satellite Networks Based on Software Defined Network

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Computers, Materials & Continua 2025年第1期82卷 863-879页

作者： Zhiguo Liu Yuqing Gui Lin Wang Yingru jiang Communication and Network Laboratory Dalian UniversityDalian116622China College of Environment and Chemical Engineering Dalian UniversityDalian116622China

Satellite edge computing has garnered significant attention from researchers;however,processing a large volume of tasks within multi-node satellite networks still poses considerable *** sharp increase in user demand for latency-sensitive tasks has inevitably led to offloading bottlenecks and insufficient computational capacity on individual satellite edge servers,making it necessary to implement effective task offloading scheduling to enhance user *** this paper,we propose a priority-based task scheduling strategy based on a Software-Defined Network(SDN)framework for satellite-terrestrial integrated networks,which clarifies the execution order of tasks based on their ***,we apply a Dueling-Double Deep Q-Network(DDQN)algorithm enhanced with prioritized experience replay to derive a computation offloading strategy,improving the experience replay mechanism within the Dueling-DDQN ***,we utilize the Deep Deterministic Policy Gradient(DDPG)algorithm to determine the optimal resource allocation strategy to reduce the processing latency of *** results demonstrate that the proposed d3-DDPG algorithm outperforms other approaches,effectively reducing task processing latency and thus improving user experience and system efficiency.

关键词： Satellite network edge computing task scheduling computing offloading