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A case report of significant progression after FFR-guided deferred PCI

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Journal of Geriatric Cardiology 2020年第10期17卷 649-652页

作者： Cheng-Duo ZHANG xin-ye xu Li-Jun GUO Wei GAO Department of Cardiology Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesBeijingChina

In recent years,the use of coronary functional evaluation derived by fractional flow reserve(FFR)to guide percutaneous coronary intervention(PCI)treatment has been recommended by several mainstream ***,FFR>0.80 in cor... 详细信息

关键词： Delayed lesion intervention Fractional flow reserve Intermediate lesion Intravascular imaging Unstable plaques

SAW chirp Fourier transform for MB-OFDM UWB receiver

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The Journal of China Universities of Posts and Telecommunications 2006年第3期13卷 1-4页

作者： HE Peng-fei LUE Ying-hua ZHANG Hong-xin WANG ye-qiu xu Yong Institute of Telecommunication and Network Technology Beijing University of Posts and Telecommunications Beijing 100876 China

In the conventional multiband orthogonal frequency division multiplexing ultra wideband （MB-OFDM UWB ） receiver, the fast Fourier transform （FFT） algorithm is realized by the expensive and power-consuming digital signal processor （DSP） chips. In this article, the lower power, lower cost, and lower complexity real-time analog surface acoustic wave （SAW） chirp Fourier transform devices were used to replace the DSP part. A MB-OFDM UWB receiver based on the M-C-M SAW chirp Fourier transform was presented, and the step of signal transformation from input signals was also depicted. The simulation results show that the proposed receiver provides similar bit error performance compared to the fully digital receiver when used in the channel environments proposed by the IEEE 802.15SG3a.

关键词： MB-OFDM UWB SAW chirp Fourier transform

The effect of selected alloying element additions on properties of Mg-based alloy as bioimplants： A literature review

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Frontiers of Materials Science 2013年第3期7卷 227-236页

作者： Li-Nan ZHANG Zeng-Tao HOU xin ye Zhao-Bin xu xue-Ling BAI Peng SHANG Center for Translational Medicine Research and Development Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China

This review investigates the current application limitations of Mg and Mg alloys. The key issues hindering the application of biodegradable Mg alloys as implants are their fast degradation rate and biological consideration. We have discussed the effect of some selected alloying element additions on the properties of the Mg-based alloy, especially the nutrient elements in human （Zn, Mn, Ca, St）. Different grain sizes, phase constituents and distributions consequently influence the mechanical properties of the Mg alloys. Solution strengthening and precipitation strengthening are enhanced by the addition of alloying elements, generally improving the mechanical properties. Besides, the hot working process can also improve the mechanical properties. Combination of different processing steps is suggested to be adopted in the fabrication of Mg-based alloys. Corrosion properties of these *** alloys have been measured in vitro and in vivo. The degradation mechanism is also discussed in terms of corrosion types, rates, by- products and response of the surrounding tissues. Moreover, the clinical response and requirements of degradable implants are presented, especially for the nutrient elements （Ca, Mn, Zn, Sr）. This review provides information related to different Mg alloying elements and presents the promising candidates for an ideal implant.

关键词： magnesium alloy alloying element corrosion biodegradation

Extracorporeal membrane oxygenation successfully treated massive right ventricular myocardial infaction with aneurysm

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Journal of Geriatric Cardiology 2022年第8期19卷 618-621页

作者： Cheng-Duo ZHANG Li-Jie SUN Bao-Xia CHEN Jiang-Li HAN Shao-Min CHEN xin-Yu WANG Yuan-Yuan FAN Dan LI xin-ye xu Department of Cardiology Peking University Third HospitalNHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesBeijingChina

Acute obstruction of the right coronary ar-tery(RCA)can lead to right ventricular myocardial infarction(MI),which rarely lead to cardiogenic shock(CS).Hemodynamic sta-bility could be restored through fluid resuscitation and vasoactive drugs in most ***,we present a highly representative case of refractory CS caused by massive right ventricular MI with api-cal aneurysm formation,who was successfully treated with extracorporeal membrane oxygenation(ECMO)post severe complication of acute right coronal dis-section.

关键词： ventricular aneurysm drugs

Morphometric measurement of the patella on 3D model reconstructed from CT scan images for the southern Chinese population

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Chinese Medical Journal 2014年第1期127卷 96-101页

作者： Shang Peng Zhang Linan Hou Zengtao Bai xueling ye xin xu Zhaobin Huang xu Center for Translational Medicine Research and Development Shenzhen Institutes of Advanced Technology Chinese Academy ofSciences Shenzhen Guangdong 518055 China

Background Due to racial differences in the morphology of the knee joint and due to most prostheses available in the market being designed using measurements from Caucasians,the objective of this study was to provide the morphometric data of the patella for the southern Chinese population for total knee arthroplasty （TKA）,patellar resurfacing,and prostheses *** The CT slices of the knee joint were obtained from both knees of 40 Chinese volunteers （20 females,20 males,and age from 20-25 years） by performing a computer tomographic scan.A 3D model was reconstructed by Mimics software based on the computed tomography *** metrical characteristics were measured by digital *** analysis was performed with the SPSS statistical *** The mean,standard deviation and P values of measurements and ratios were calculated using *** dimensions showed a significant gender difference with P＜0.05,but the six variables of the left and right knees had no statistical significance with P＞*** addition,we studied the relationship between six couples （H-W,H-T,H-HAF,W-T,W-HAF,T-HAF） of the four variables （H：height,W：width,T：thickness and HAF：height of articulating facet） that were measured,which showed a significant *** Examination of the southern Chinese population revealed that males have larger patellae than *** both genders,comparing data between left and right knees shows no statistically significant *** with Westerners in previous studies,the patella in our study was thin and *** was a good linear regression correlation between measurements of the *** indirect measurement method on 3D models makes it easy to obtain anatomical data,and the results can provide a region and gender specific database for morphometric measurements of the oatella,and can be helpful for designing implants suited for southern Chinese patients.

关键词： morphometric measurement patella 3D model computed tomography southern Chinese population

What Has Shaken the Determination of Medical Students to Become a Doctor？

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Chinese Medical Journal 2017年第8期130卷 1001-1002页

作者： xin-ye xu Wei Gao Ai-Jing Zhang Jing Huang Ming Cui Wei Zhao Department of Cardiology Peking University Third Hospital Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides Ministry of Health Key Laboratory of Molecular Cardiovascular Sciences Ministry of Education Beijing Key Laboratory of Cardiovascular Receptors Research Beijing 100191 China Division of Education Peking University Third Hospital Beijing 100191 China

The scarcity of doctors is common in underdeveloped countries as well as in some developing and developed countries including Japan, Germany, Australia, Korea, and even the United States of America, indicating that this scarcity has become a global issue. Causes vary from country to country. In China, the causes of this shortage are complicated. Due to increasing violence in recent years against medical staff that endangers the personal safety of medical practitioners, the number of Chinese medical school applicants has decreased greatly. Furthermore, the proportion of students who abandon the health sector is very high.

关键词： Career Choice Occupational Risk Social Status

Study of optical clocks based on ultracold ^171Yb atoms

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Chinese Physics B 2020年第9期29卷 79-83页

作者： Di Ai Hao Qiao Shuang Zhang Li-Meng Luo Chang-Yue Sun Sheng Zhang Cheng-Quan Peng Qi-Chao Qi Tao-Yun Jin Min Zhou xin-ye xu State Key Laboratory of Precision Spectroscopy East China Normal UniversityShanghai 200062China Shanghai Research Center for Quantum Sciences Shanghai 201315China

The optical atomic clocks have the potential to transform global timekeeping,relying on the state-of-the-art accuracy and stability,and greatly improve the measurement precision for a wide range of scientific and technological *** we report on the development of the optical clock based on 171Yb atoms confined in an optical lattice.A minimum width of 1.92-Hz Rabi spectra has been obtained with a new 578-nm clock interrogation *** in-loop fractional instability of the 171Yb clock reaches 9.1×10-18 after an averaging over a time of 2.0×104 *** synchronous comparison between two clocks,we demonstrate that our 171Yb optical lattice clock achieves a fractional instability of 4.60×10-16/√τ.

关键词： cold ytterbium atoms optical clocks ultra-stable clock lasers clock-transition spectra instability and uncertainty

The burden of upper motor neuron involvement is correlated with the bilateral limb involvement interval in patients with amyotrophic lateral sclerosis:a retrospective observational study

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Neural Regeneration Research 2025年第5期20卷 1505-1512页

作者： Jieying Wu Shan ye Xiangyi Liu Yingsheng xu Dongsheng Fan Department of Neurology Peking University Third HospitalBeijingChina Beijing Municipal Key Laboratory of Biomarker and Translational Research in Neurodegenerative Diseases BeijingChina Key Laboratory for Neuroscience National Health Commission/Ministry of EducationPeking UniversityBeijingChina

Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor *** bilateral limb involvement significantly affects patients'daily lives and may lead them to be confined to ***,the effect of upper and lower motor neuron impairment and other risk factors on bilateral limb involvement is *** address this issue,we retrospectively collected data from 586 amyotrophic lateral sclerosis patients with limb onset diagnosed at Peking University Third Hospital between January 2020 and May 2022.A univariate analysis revealed no significant differences in the time intervals of spread in different directions between individuals with upper motor neuron-dominant amyotrophic lateral sclerosis and those with classic amyotrophic lateral *** used causal directed acyclic graphs for risk factor determination and Cox proportional hazards models to investigate the association between the duration of bilateral limb involvement and clinical baseline characteristics in amyotrophic lateral sclerosis *** factor analyses revealed that higher upper motor neuron scores(hazard ratio[HR]=1.05,95%confidence interval[CI]=1.01–1.09,P=0.018),onset in the left limb(HR=0.72,95%CI=0.58–0.89,P=0.002),and a horizontal pattern of progression(HR=0.46,95%CI=0.37–0.58,P<0.001)were risk factors for a shorter interval until bilateral limb *** results demonstrated that a greater degree of upper motor neuron involvement might cause contralateral limb involvement to progress more quickly in limb-onset amyotrophic lateral sclerosis *** findings may improve the management of amyotrophic lateral sclerosis patients with limb onset and the prediction of patient prognosis.

关键词： amyotrophic lateral sclerosis bilateral limb involvement Cox proportional hazards regression model horizontal spread restricted cubic spline analysis time interval upper motor neuron vertical spread

珠江河口不同类型湿地底栖肉足虫群落的初步研究

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水生态学杂志 2017年第4期38卷 57-64页

作者：叶欣徐润林中山大学生命科学学院广州510275

为了积累和丰富河口湿地生态学研究,进而为湿地环境的生物监测和评价提供理论依据,对采自珠江口淇澳岛3种类型湿地(狐尾藻湿地、芦苇湿地和秋茄湿地)的底泥,利用非淹没培养皿法对底栖肉足虫群落进行了分类研究,采用"3级10倍"法对肉足虫... 详细信息

为了积累和丰富河口湿地生态学研究,进而为湿地环境的生物监测和评价提供理论依据,对采自珠江口淇澳岛3种类型湿地(狐尾藻湿地、芦苇湿地和秋茄湿地)的底泥,利用非淹没培养皿法对底栖肉足虫群落进行了分类研究,采用"3级10倍"法对肉足虫进行了定量分析,并按国家标准分析了底泥样品的理化指标;利用统计学软件分析了底栖肉足虫群落多样性指数、底栖肉足虫丰度及其与底泥理化因子间的关系。结果表明,在全部样品中,共检到4纲、6目、54属肉足虫68种;变形目、表壳目和太阳虫目种类占全部种类的绝大部分(87.4%);各种类的功能营养类别显示,淇澳岛不同类型湿地底栖肉足虫的营养类型复杂,以B-食细菌与碎屑者的比例最高(占总数量的42.62%);底栖肉足虫的丰度为0.92×10~4~23.0×10~4个/g,平均丰度的最高值出现在秋茄湿地(7.1×10~4个/g);Margalef多样性指数为0.083~0.639,平均值以狐尾藻湿地最高;各类型湿地底栖肉足虫群落平均丰度间及不同季节间底栖肉足虫群落丰度均无显著差异(P≥0.05)。相关性分析表明,各湿地中底栖肉足虫丰度与底泥理化指标间均无显著相关;比较分析显示,淇澳岛湿地底栖肉足虫群落组成分布更符合Foissner的"生物地理模型(Biogeography model)"。

关键词：底栖原生动物肉足虫湿地类型珠江口