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Computer Modeling in Engineering & Sciences 2025年第1期142卷 329-355页

作者： Yufeng xing ye yuan Gen Li Institute of Solid Mechanics Beihang University(BUAA)Beijing100191China

The separation-of-variable(SOV)methods,such as the improved SOV method,the variational SOV method,and the extended SOV method,have been proposed by the present authors and coworkers to obtain the closed-form analytical solutions for free vibration and eigenbuckling of rectangular plates and circular cylindrical *** taking the free vibration of rectangular thin plates as an example,this work presents the theoretical framework of the SOV methods in an instructive way,and the bisection–based solution procedures for a group of nonlinear eigenvalue ***,the explicit equations of nodal lines of the SOV methods are presented,and the relations of nodal line patterns and frequency orders are *** is concluded that the highly accurate SOV methods have the same accuracy for all frequencies,the mode shapes about repeated frequencies can also be precisely captured,and the SOV methods do not have the problem of missing roots as well.

关键词： Separation-of-variable method Rayleigh quotient nodal line eigenvalue equation bisection method

Characterization of size-resolved aerosol hygroscopicity and liquid water content in Nanjing of the Yangtze River Delta

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Journal of Environmental Sciences 2025年第5期151卷 26-41页

作者： Youling Jiang Yan Ma Jun Zheng Nan ye Cheng yuan School of Environmental Science and Engineering Nanjing University of Information Science and TechnologyNanjing 210044China Collaborative Innovation Center of Atmospheric Environment and Equipment Technology Nanjing University of Information Science&TechnologyNanjing 210044China School of Emergency Management Nanjing University of Information Science&TechnologyNanjing 210044China

Aerosol hygroscopicity and liquid water content(ALWC)have important influences on the environmental and climate effect of *** this study,we measured the hygroscopic growth factors(GF)of particles with dry diameters of 40,80,150,and 200 nm during the wintertime in *** the GF-derived hygroscopicity parameter(κ_(gf))and ALWC increased with particle size,but displayed differing diurnal variations,withκ_(gf)peaking around the midday,while ALWC peaking in the early ***,ammonium and oxygenated organic aerosols(OOA)were found as the chemical components mostly strongly correlated with ALWC.A closure study suggests that during midday photo-oxidation and nighttime high ALWC periods,theκof organic aerosols(κ_(org))was underestimated when using previous ***,we re-constructed parameterizations forκ_(org)and the oxidation level of organics for these periods,which indicates a higher hygroscopicity of photochemically formed OOA than the aqueous OOA,yet both being much higher than the generally assumed OOA ***,in a typical high ALWC episode,concurrently increased ALWC,nitrate,OOA as well as aerosol surface area and mass concentrations were observed under elevated ambient *** strongly indicates a coupled effect that the hygroscopic secondary aerosols,in particular nitratewith strong hygroscopicity,led to large increase in ALWC,which in turn synergistically boosted nitrate and OOA formation by heterogeneous/aqueous *** interaction may represent an important mechanism contributing to enhanced formation of secondary aerosols and rapid growth of fine particulate matter under relatively high RH conditions.

关键词： Aerosol hygroscopicity Aerosol liquid water content Photo-oxidation Aqueous/heterogeneous reactions

Trigonelline exerts its neuroprotective effects in experimental spinal cord injury through modulation of inflammation, apoptosis, and neurotrophic factors

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Asian Pacific Journal of Tropical Biomedicine 2025年第1期15卷 34-42页

作者： Zhi-Lan ye yuan Cao Department of Rehabilitation Jingdezhen Hospital of Traditional Chinese MedicineJingdezhen333000China Department of Neurosurgery General Hospital of Northern Theater CommandShenyang110000China

Objective:To assess the protective effects of trigonelline against spinal cord injury(SCI)in ***:Rats(Sprague-Dawley,male)were randomly assigned to seven groups(n=15 per group):normal,sham,SCI control(1%DMSO),methylprednisolone(30 mg/kg),and trigonelline(50,100,and 200 mg/kg).Rats received respective treatment daily for 28 *** was induced by using a temporary aneurysm ***,biochemical,and histological analyses were performed to investigate the neuroprotective effect of ***:Trigonelline(100 and 200 mg/kg)treatment effectively(P<0.05)mitigated SCI-induced changes in mechano-tactile sensation,allodynia,hyperalgesia,and motor nerve conduction *** notably(P<0.05)downregulated apoptotic(Bax and caspase-3)and inflammatory(COX-Ⅱ)markers,while upregulating Bcl-2 and BDNF mRNA expression in the spinal cord(P<0.05).Furthermore,trigonelline effectively alleviated(P<0.05)SCI-induced alterations in mitochondrial complex levels,resulting in enhanced nicotinamide adenine dinucleotide dehydrogenase,succinate dehydrogenase,redox activity,and cytochrome-C *** examination of spinal cord tissue indicated that trigonelline significantly(P<0.05)ameliorated the histological damage caused by SCI,thereby improving neuronal degeneration,inflammatory cell infiltration,and ***:Trigonelline shows neuroprotective properties in SCI rats by reducing allodynia,hyperalgesia,and inflammation,stabilizing mitochondrial enzyme complexes,and modulating apoptotic and neurotrophic ***,trigonelline holds promise as a potential neuroprotective agent.

关键词： Bax Bcl-2 BDNF COX-Ⅱ Spinal cord injury Trigonelline

Prioritization Hindsight Experience Based on Spatial Position Attention for Robots

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Machine Intelligence Research 2025年第1期22卷 160-175页

作者： ye yuan Yu Sha Feixiang Sun Haofan Lu Shuiping Gou Jie Luo China Nuclear Power Technology Research Institute Co. Ltd.Shenzhen518028China School of Artificial Intelligence Xidian UniversityXi’an710071China Suzhou Tianhe China Power International Engineering Technology Co. Ltd.Suzhou215000China

Sparse rewards pose significant challenges in deep reinforcement learning as agents struggle to learn from experiences with limited reward *** experience replay(HER)addresses this problem by creating“small goals”within a hierarchical decision ***,HER does not consider the value of different episodes for agent *** this paper,we propose SPAHER,a framework for prioritizing hindsight experiences based on spatial position *** allows the agent to prioritize more valuable experiences in a manipulation *** achieves this by calculating transition and trajectory spatial position functions to determine the value of each episode for experience *** evaluate SPAHER on eight robot manipulation tasks in the Fetch and Hand environments provided by OpenAI *** results show that our method improves the final mean success rate by an average of 3.63%compared to HER,especially in challenging Hand ***,these improvements are achieved without any increase in computation time.

关键词： Hindsight experience replay spatial position attention sparse reward deep reinforcement learning prioritization hindsight experience

Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder

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Neural Regeneration Research 2025年第6期20卷 1541-1554页

作者： Jinmei ye Cong Duan Jiaxin Han Jinrong Chen Ning Sun yuan Li Tifei yuan Daihui Peng Division of Mood Disorder Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina

In the pathogenesis of major depressive disorder, chronic stress-related neuroinflammation hinders favorable prognosis and antidepressant response. Mitochondrial DNA may be an inflammatory trigger, after its release from stress-induced dysfunctional central nervous system mitochondria into peripheral circulation. This evidence supports the potential use of peripheral mitochondrial DNA as a neuroinflammatory biomarker for the diagnosis and treatment of major depressive disorder. Herein, we critically review the neuroinflammation theory in major depressive disorder, providing compelling evidence that mitochondrial DNA release acts as a critical biological substrate, and that it constitutes the neuroinflammatory disease pathway. After its release, mitochondrial DNA can be carried in the exosomes and transported to extracellular spaces in the central nervous system and peripheral circulation. Detectable exosomes render encaged mitochondrial DNA relatively stable. This mitochondrial DNA in peripheral circulation can thus be directly detected in clinical practice. These characteristics illustrate the potential for mitochondrial DNA to serve as an innovative clinical biomarker and molecular treatment target for major depressive disorder. This review also highlights the future potential value of clinical applications combining mitochondrial DNA with a panel of other biomarkers, to improve diagnostic precision in major depressive disorder.

关键词： biomarker cytokine exosomes inflammasome major depressive disorder microglia mitochondrial DNA mitochondrial dysfunction neuroinflammation Toll-like receptor

First commissioning results of the coherent scattering and imaging endstation at the Shanghai soft X-ray free-electron laser facility

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Nuclear Science and Techniques 2022年第9期33卷 48-58页

作者： Jia-Dong Fan Ya-Jun Tong Yong-Gan Nie Zi-Chen Gao Bo He Hui Luan Dong-Hao Lu Jian-Hua Zhang Di-Fei Zhang xin-ye yuan Jia-Hua Chen Zhi Guo Tao Liu Meng Zhang Chao Feng Hai-Xiao Deng Bo Liu Zhen-Tang Zhao Zhi Liu Huai-Dong Jiang Center for Transformative Science ShanghaiTech UniversityShanghai 201210China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China

The Shanghai soft X-ray free-electron laser(SXFEL)user facility project started in 2016 and is expected to be open to users by *** aims to deliver ultra-intense coherent femtosecond X-ray pulses to five endstations covering a range of 100–620 eV for ultrafast X-ray *** undulator lines are designed and constructed,based on different lasing modes:self-amplified spontaneous emission and echo-enabled harmonic *** coherent scattering and imaging(CSI)endstation is the first of five endstations to be commissioned *** focuses on high-resolution single-shot imaging and the study of ultrafast dynamic processes using coherent forward scattering *** the single-shot holograms and coherent diffraction patterns were recorded and reconstructed for nanoscale imaging,indicating the excellent coherence and high peak power of the SXFEL and the possibility of‘‘diffraction before destruction’’experiments at the CSI *** this study,we report the first commissioning results of the CSI endstation.

关键词： X-ray free electron laser Coherent diffraction imaging Fourier transform holography Single-shot imaging Phase retrieval

Physical Layer Security Scheme With AoI-Awareness for Industrial IoT Based on Covert Communications

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IEEE/CAA Journal of Automatica Sinica 2025年第1期12卷 276-278页

作者： Yaping Li Zhi-xin Liu Jia-Wei Su Ya-Zhou yuan the Key Laboratory of Industrial Computer Control Engineering of Hebei Province Yanshan University

Dear Editor,Industrial Internet of things(IIoT) is a typical application of cyberphysical system(CPS). In the IIoT, wireless communication is an inevitable trend to replace the deployment-limited wired transmission for cases with large-scale and mobile devices. However, wireless communication gives rise to critical issues related to physical security, such as malicious detections and attacks [1].

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Understanding and probing progression of localized corrosion on inner walls of steel pipelines:an overview

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Journal of Iron and Steel Research International 2025年第1期32卷 1-18页

作者： Ming-yu Wang Hai-yuan Yao Yong-fei Liu ye-sen Zhu Wan-bin Chen Yun-ze Xu Yi Huang School of Naval Architecture and Ocean Engineering Dalian University of TechnologyDalian 116024LiaoningChina China National Offshore Oil Corporation Research Institute Co. Ltd.Beijing 100028China State Key Laboratory of Structural Analysis Optimization and CAE Software for Industrial EquipmentDalian University of TechnologyDalian 116024LiaoningChina

Corrosion poses a major threat to the safety of transportation ***,it is crucial to have an in-depth understanding of corrosion mechanisms in pipeline steels for the effective management of pipeline *** research on corrosion mechanisms relies on the use of efficient and reliable corrosion monitoring and analysis *** advancements in corrosion monitoring techniques specifically designed for the localized corrosion monitoring were aimed to be introduced,and a comprehensive overview of recent progress in understanding the localized corrosion mechanisms in pipeline steels was *** on the different corrosive environments encountered,the localized corrosion issues inside pipelines are classified into two categories:localized corrosion primarily influenced by electrochemical processes and localized corrosion controlled by both electrochemical and mechanical ***,a thorough analysis of the synergistic effects between micro-cell and macro-cell currents,as well as the interplay of mechanics and electrochemistry is ***,recommendations for future research on the mechanisms of internal localized corrosion in pipelines are provided.

关键词： Pipeline steel Localized corrosion Corrosion type Corrosion monitoring Corrosion mechanism

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简论“对话”理论及其对语文阅读教学的影响

教育导刊（上半月） 2008年第7期 15-17页

作者：钟家莲叶新源赣南师范学院文学院教授硕士生导师江西赣州341000

"对话"是内涵丰富、歧义甚多的流行术语,在不同的领域其能指与所指全然不同。因此,有必要回到原点,对"对话"理论做一次梳理,阐明阅读教学中对话的本质及特征。"对话"理论对语文阅读教学的影响主要表现在:奠定了当代阅读学的理论基础,创... 详细信息

"对话"是内涵丰富、歧义甚多的流行术语,在不同的领域其能指与所指全然不同。因此,有必要回到原点,对"对话"理论做一次梳理,阐明阅读教学中对话的本质及特征。"对话"理论对语文阅读教学的影响主要表现在:奠定了当代阅读学的理论基础,创新了阅读教学的基本理念,带来了阅读教学策略的系列变革。

关键词：对话理论阅读教学影响

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时空众包数据管理技术研究综述

软件学报 2017年第1期28卷 35-58页

作者：童咏昕袁野成雨蓉陈雷王国仁软件开发环境国家重点实验室(北京航空航天大学) 北京100191 北京航空航天大学计算机学院北京100191 东北大学计算机科学与工程学院辽宁沈阳110004 香港科技大学计算机科学与工程学系

近年来,众包为传统数据管理提供了一种通过汇聚群体智慧求解问题的新模式,并成为当前数据库领域的研究热点之一.特别是随着移动互联网技术与共享经济模式的快速发展,众包技术已融入到各类具有时空数据的应用场景中,例如各类O2O(online-t... 详细信息

近年来,众包为传统数据管理提供了一种通过汇聚群体智慧求解问题的新模式,并成为当前数据库领域的研究热点之一.特别是随着移动互联网技术与共享经济模式的快速发展,众包技术已融入到各类具有时空数据的应用场景中,例如各类O2O(online-to-offline)应用、实时交通监控与动态物流管理等.简言之,这种应用众包技术处理时空数据的方式称为时空众包数据管理.对近期在时空众包数据管理方面的研究工作进行综述,首先阐述了时空众包的概念,解释了其与传统众包技术的关系,并介绍了各类典型的时空众包应用;随后描述了时空众包应用平台的工作流程及其任务特点;然后讨论了时空众包数据管理的3项核心研究问题和3类应用技术;最后,总结了时空众包数据管理技术的研究现状并展望了其未来潜在的研究方向,为相关研究人员提供了有价值的参考.

关键词：时空众包共享经济 O2O模式任务分配质量控制隐私保护