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A New Furostanol Saponin from Dioscorea futshauensis

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Chinese Chemical Letters 2002年第3期13卷 241-244页

作者： Hong Wei LIU Ge Xia QU xin sheng yao Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110015

A new furostanol saponin presenting moderate bioactivity of inducing morphological deformation of Pyricularia oryzae mycelia was isolated from Dioscorea futshauensis *** by bioactivity-guided fractionation. The structure was established as 26-O-b-D-glucopyranosyl-3b, 26-diol-23(S)-methoxyl-(25R)-furost-5,20 (22)-diene-3-O-[a-L-rhamnopyranosyl (12)-b-D- glucopyranosyl (13)]-b-D-glucopyranoside on the basis of chemical evidencesand spectral analysis, especially by 2D-NMR techniques.

关键词： Furostanol glycoside Dioscorea futshauensis Pyricularia oryzae.

Two new phenolic compounds from Ardisia gigantifolia

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Chinese Chemical Letters 2008年第6期19卷 693-695页

作者： Zhu Yang Ping Wen Nai Li Wang xin sheng yao College of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China Shenzhen Key Laboratory for New Drugs Research of Traditional Chinese Medicines Research Institute of Tsinghua University Shenzhen 518057 China

Two new compounds were isolated from the 60% ethanol extract of the dried rhizome of Ardisia gigantifolia Stapf. The structures were elucidated on the basis of spectroscopic methods as （＋）-5-（1,2-dihydroxypentyl）... 详细信息

关键词： Ardisia gigantifolia Stapf Phenolic compounds 5-(1,2-Dihydroxypentyl)benzene-1,3-diol

A new protoberberine alkaloid from Corydalis yanhusuo ***

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Chinese Chemical Letters 2009年第8期20卷 955-957页

作者： Tian Tian Hu Xue Zhang Shi Zhong Ma xin sheng yao School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

A new protoberberine alkaloid, named 5,6-dihydro- 10-hydroxy-2,3,9-trimethoxy- 13-methyldibenzo[α,g]quinoliziniurn （1） was isolated from the 60% ethanol extract of the tubers of Corydalis yanhusuo W. T. Wang, together with a new natural product, 13methylpalmatrubine （2）. Their structures were established by spectroscopic methods. 2009 xin sheng yao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All fights reserved.

关键词： Corydalis yanhusuo W. T. Wang Protoberberine alkaloid 13-Methylpalmatrubine

A New Spirostanol Saponin from Dioscorea futshauensis

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Chinese Chemical Letters 2001年第7期12卷 613-616页

作者： Hong Wei LIU Hisayoshi KOBAYASHI Ge Xia QU xin sheng yao Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110015 Institute of Molecular&Cellular Biosciences The University of TokyoTokyoJapan 113

A new spirostanol saponin presenting strong activity of inducing morphological deformation of Pyricularia oryzae mycelia was isolated from Dioscorea futshauensis R. Kunth by bioactivity-guided fractionation. The structure was established as (25S)-spirost-5-en-3 beta, 27-diol-3-O- [alpha -L-rhamnopyranosyl (1 -->2)-beta -D glucopyranosyl (1 -->3)]-beta -D-glucopyranoside on the basis of chemical evidences and spectral analysis, especially by 2D-NMR techniques.

关键词： New spirostanol glycoside Dioscorea futshauensis Pyricularia oryzae

A New Alkaloid from Sinomenium acutum

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Chinese Chemical Letters 2005年第11期16卷 1481-1483页

作者： Wei Ming CHENG Feng QIU Li Jun WU xin sheng yao Department of Natural Products Chemistry Shenyang Pharmaceutical University Shenyang 110016

Sinomenium acutum is widely used in East and South Asia for the treatment of many diseases, especially rheumatoid arthritis （RA）. The chemical research on Sinomenium acutum led to the isolation of a new alkaloid compound （1）. On the basis of chemical evidences and spectral analysis, 1 was identified as N-（1, 7-dimethoxylphenanthren-2-yl）acetamide.

关键词： Sinomenium acutum alkaloid N-(l 7-dimethoxylphenanthren-2-yl)acetamide.

A New Triterpenoid Spaonin Isolated from the Seeds of Aesculus assamica Griff

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Chinese Chemical Letters 2006年第2期17卷 211-214页

作者： Hong Wei LIU xin sheng yao Nai Li WANG Guo Ping CAI Life Scinece Division Graduate School at Shenzhen Tsinghua University Shenzhen 518055 Key lab for Research and Development of New Drugs Shenzhen 518055 School of Traditional Chinese Matcria Medica Shcnyang Pharmaceutical University Shenyang 110016

A new triterpenoid saponin, 21 β-angeloylprotoaescigenin-3β-O- [α-L-rhamnopyranosyl- （1-3）]β-D-glucopyranosiduronic acid 1, was isolated from the seeds of Aesculus assamica Griff. Its structure was elucidated on... 详细信息

关键词： Aesculus assamica triterpenoid saponin Pyricularia oryzae.

Iridoid glycosides from the roots of Scrophularia ningpoensis Hemsl

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Chinese Chemical Letters 2014年第10期25卷 1354-1356页

作者： Ling-Juan Zhu Cheng Qiao Xiu-Yu Shen Xue Zhang xin-sheng yao College of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education Shenyang Pharmaceutical University Institute of Traditional Chinese Medicine & Natural Products College of PharmacyJinan University

Two new iridoid glycosides,named scrophularianoids A（1） and B（2）,were isolated from the roots of Scrophularia *** chemical structures were established on the basis of extensive analyses of spectroscopic *** 1 and ... 详细信息

关键词： Scrophularia ningpoensis lridoid glycosides Scrophularianoid A Scrophularianoid B

A new triterpenoid saponin from the roots of Ardisia crenata

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Chinese Chemical Letters 2011年第8期22卷 957-960页

作者： Dai Lin Liu Xue Zhang Shu Ping Wang Nai Li Wang xin sheng yao Tianjin Key Laboratory for Biomarkers of Occupational and Environmental Hazard. Tiajin 300162 China Department of Pharmacognosy. Medical College of Chinese People's Armed Police Forces Tianjin 300162 China Department of Natural Products Chemistry Shenyang Pharmaceutical University Shenyang 110016 China

A new triterpenoid saponin.3 β-O-{ β-D-glucopyranosyl-（1—4）-[ β-D-glucopyranosyl-[1-2）]- α-L-arabinopyranosyl}-16α, 28-dihydroxyolean-12-en-30-oic acid 30-O- β-D-glucopyranosyl ester（ardisicrenoside N.1）,together with two known saponins, ardisicrenoside C（2） and D（3）,were isolated from the roots of Ardisia crenata *** structures were elucidated by extensive spectral analysis and chemical *** 1 showed cytotoxicity against MCI-7 and NCI-H460 cancer cell lines at 11.0μmol/L and 22.1μmol/L in vitro.

关键词： Ardisia crenata Sims Ardisicrenoside N Cytotoxicity

8-O-4’ Neolignan glycosides from the aerial parts of Matteuccia struthiopteris

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Chinese Chemical Letters 2016年第1期27卷 63-65页

作者： Ling-Juan Zhu Fei Yan Jin-Peng Chen Nan Zhang Xue Zhang xin-sheng yao College of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Key Laboratory of Structure-Based Drug Design & Discovery of Ministry of Education Shenyang Pharmaceutical University State Key Laboratory of Bioactive Substance and Function of Natural Medicines Institute of Materia Medica Chinese Academy of Medical Sciences and Peking Union Medical College Institute of Traditional Chinese Medicine & Natural Products College of Pharmacy Jinan University

Two new 8-O-4＇ neolignan glycosides, named matteustruthiosides A（1） and B（2） were isolated from the aerial parts of Matteuccia struthiopteris. Their chemical structures were characterized on the basis of various spectroscopic techniques. The absolute configurations of them were determined by experimental circular dichroism（CD） spectra. Compounds 1 and 2 were inactive against influenza A（H1N1） virus in vitro.

关键词： Matteuccia struthiopteris 8-O-4' Neolignan glycosides Matteustruthioside A Matteustruthioside B