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Transparent micropatterned conductive films based on highlyordered nanowire network

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Nano Research 2024年第5期17卷 4288-4297页

作者： xin-ran Zhang Hai-Tao Deng Xu Zeng Yi-Lin Wang Peng Huang Xiao-Sheng Zhang School of Integrated Circuit Science and Engineering University of Electronic Science and Technology of ChinaChengdu 611731China

Transparent conductive films that are based on nanowire networks are essential to construct flexible,wearable,and even stretchable ***,large-scale precise micropatterning,especially with regard to the controllability of the organizing orientation of nanowires,is a critical ***,we proposed a liquid film rupture self-assembly approach for manufacturing transparent conductive films with microstructure arrays based on a highly ordered nanowire *** large-scale microstructure conductive films were fabricated through air-liquid interface self-assembly and liquid film rupture *** typical micropattern morphologies,including square,hexagon,circle,serpentine,etc.,were prepared to reveal the universal applicability of the proposed *** homogeneity and controllability of this approach were verified for multiple *** the assembly cycles increasing,the optical transmittance decreases *** addition,theoretical model analysis is carried out,and the analytical formula of the speed of the film moving with the surface tension and the density of the liquid film is ***,the feasibility of this approach for piezoresistive strain sensors is *** fabrication approach demonstrated a cost-effective and efficient method for precisely arranging nanowires,which is useful in transparent and wearable applications.

关键词： flexible electronics transparent conductive network micropatterning nanowires micro electromechanical systems(MEMS)

Selective synthesis of the B_(11)H_(14)^(-) and B_(12)H_(12)^(2-) borane derivatives and the general mechanisms of the B-H bond condensation

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Science China Chemistry 2024年第3期67卷 876-881页

作者： Yi Jing xinghua Wang Hui Han xin-ran Liu xing-Chao Yu Xi-Meng Chen Donghui Wei Lai-Sheng Wang Xuenian Chen College of Chemistry Green Catalysis CenterZhengzhou UniversityZhengzhou 450001China School of Chemistry and Chemical Engineering Henan Key Laboratory of Boron Chemistry and Advanced Energy MaterialsHenan Normal UniversityXinxiang 453007China Department of Chemistry Brown UniversityProvidenceRI 02912USA

Polyhedral boranes are a class of well-known boron molecular clusters with unique physical and chemical properties,and great efforts have been made in the past decades to find more effective synthetic ***,the established synthetic methods suffer from low efficiency and low selectivity because the mechanism of the B-H bond condensation reaction,critical for the synthesis of the polyhedral boranes,is not well *** we report highly selective and efficient synthetic methods of the salts of the tetradecahydridoundecaborate(1-)(B_(11)H^(-)_(14)) and dodecahydrido-dodecaborates(2-)(B_(12)H_(12)^(2-)) anions by employing commercially available and inexpensive starting *** theoretical and experimental investigations are carried out to elucidate the reaction *** have found that the nature of the B-H bond condensation is the dihydrogen bonding interaction in which the positively charged hydrogens(bridged hydrogens) play a crucial *** current study has not only led to more effective and selective synthetic methods for B_(11)H^(-)_(14) and B_(12)H_(12)^(2-) but also unveiled the nature of the B-H bond condensation and the general formation mechanisms of polyhedral *** finding will facilitate the development of more effective synthetic methods for polyhedral boranes and spur their wide application.

关键词： Boranes polyhedral boranes dihydrogen bond nucleophilicity

Knockdown of fibrillin-1 suppresses retina-blood barrier dysfunction by inhibiting vascular endothelial apoptosis under diabetic conditions

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International Journal of Ophthalmology(English edition) 2024年第8期17卷 1403-1410页

作者： Yue Zhang Xiao-Jing Liu xin-ran Zhai Yao Yao Bin Shao Yu-Han Zhen xin Zhang Zhe Xiao Li-Fang Wang Ming-Lian Zhang Zhi-Min Chen Hebei Eye Hospital Provincial Key Laboratory of OphthalmologyHebei Provincial Clinical Research Center for Eye DiseasesXingtai 054001Hebei ProvinceChina Department of Ophthalmology Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina

AIM:To investigate the effects of fibrillin-1(FBN1)deletion on the integrity of retina-blood barrier function and the apoptosis of vascular endothelial cells under diabetic ***:Streptozotocin(STZ)-induced diabetic mice were used to simulate the diabetic conditions of diabetic retinopathy(DR)patients,and FBN1 expression was detected in retinas from STZ-diabetic mice and *** the Gene Expression Omnibus(GEO)database,the GSE60436 dataset was selected to analyze FBN1 expressions in fibrovascular membranes from DR *** lentivirus to knock down FBN1 levels,vascular leakage and endothelial barrier integrity were detected by Evans blue vascular permeability assay,fluorescein fundus angiography(FFA)and immunofluorescence labeled with tight junction marker in *** glucose-induced monkey retinal vascular endothelial cells(RF/6A)were used to investigate effects of FBN1 on the cells in *** vascular endothelial barrier integrity and apoptosis were detected by trans-endothelial electrical resistance(TEER)assay and flow cytometry,***:FBN1 mRNA expression was increased in retinas of STZ-induced diabetic mice and fibrovascular membranes of DR patients(GSE60436 datasets)using RNA-seq ***,knocking down of FBN1 by lentivirus intravitreal injection significantly inhibited the vascular leakage compared to STZ-DR group by Evans blue vascular permeability assay and FFA *** of tight junction markers in STZ-DR mouse retinas were lower than those in the control group,and knocking down of FBN1 increased the tight junction *** vitro,30 mmol/L glucose could significantly inhibit viability of RF/6A cells,and FBN1 mRNA expression was increased under 30 mmol/L glucose ***-regulation of FBN1 reduced high glucose(HG)-stimulated retinal microvascular endothelial cell permeability,increased TEER,and inhibited RF/6A cell apoptosis in ***:The expression level of FBN1 increases in reti

关键词： diabetic retinopathy fibrillin-1 retinablood barrier vascular leakage vascular permeability apoptosis retinal vascular endothelial cells

Phlorizin alleviates mastitis and preserves the blood-milk barrier by metabolizing into phloretin

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Food Science and Human Wellness 2024年

作者： xin ran Kefei Li Juxiong Liu Xiaoxuan Wang Wenjin Guo Guiqiu Hu Shoupeng Fu State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases， Key Laboratory for Zoonosis Research of the Ministry of Education， Institute of Zoonosis， and College of Veterinary Medicine， Jilin University

Mastitis is a common disease that affects women during lactation， posing a threat to the health of both mothers and infants. Recent studies have shown that insufficient nutrient intake increase the risk of mastitis. Phlorizin (PHZ) is one of the nutrients present in apples. This study uses Lipopolysaccharide (LPS)-induced mastitis mice and LPS+ATP-stimulated mouse mammary epithelial cells (mMECs) as research objects to explore the effect and mechanism of PHZ on mastitis. Different to in vitro beliefs， our findings demonstrated that PHZ significantly reduced inflammation and protected the blood–milk barrier (BMB) in vivo. Additionally， we observed that oral administration of PHZ regulated the intestinal flora and exhibited prebiotic functions. However， the anti-inflammatory effect of PHZ was not solely dependent on the intestinal flora， as antibiotic disruption of the intestinal flora does not completely abolish the improvement of mastitis by PHZ. Further mechanistic research revealed that the anti-inflammatory properties of PHZ were attributed to its metabolism into phloretin (PHT). Moreover， our results demonstrated that PHT reduced inflammation and protected the BMB by promoting autophagy to prevent the pyroptosis of mMECs. This study provides a theoretical basis for reducing inflammation in lactating women by consuming fruits， such as apples， that contain PHZ.

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几类near MDS码和最优局部修复码的构造

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电子学报 2024年第3期52卷 957-966页

作者：王鑫然衡子灵长安大学理学院陕西西安710064

局部修复码是一种通过局部修复提高存储节点修复效率的重要编码方法,在分布式存储和云存储中有重要应用.本文首先构造了几类维数为4或5的near MDS(near Maximum Distance Separable)码,精确计算出了它们的参数和重量分布.特别地,得到了... 详细信息

局部修复码是一种通过局部修复提高存储节点修复效率的重要编码方法,在分布式存储和云存储中有重要应用.本文首先构造了几类维数为4或5的near MDS(near Maximum Distance Separable)码,精确计算出了它们的参数和重量分布.特别地,得到了一些参数相同但重量分布不同的near MDS码.此外,通过确定near MDS码的局部度,得到了几类距离最优和维数最优的局部修复码.这些局部修复码的参数和文献中已知最优局部修复码的参数不同.

关键词： near MDS码重量分布局部修复码分布式存储

TCERG1L hypermethylation is a risk factor of diabetic retinopathy in Chinese children with type 1 diabetes

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International Journal of Ophthalmology(English edition) 2024年第3期17卷 537-544页

作者： Yu Qian Ying Xiao Qiu-Rong Lin Zhao-Yu Xiang Li-Pu Cui Jia-Qi Sun Si-Cong Li xin-ran Qin Hai-Dong Zou Chen-Hao Yang Pei-Yao Jin Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai First People’s HospitalShanghai 200080China Shanghai Eye Diseases Prevention&Treatment Center Shanghai Eye HospitalShanghai 200040China National Clinical Research Center for Eye Diseases Shanghai Clinical Research Center for Eye DiseasesShanghai Key Clinical SpecialtyShanghai Key Laboratory of Ocular Fundus DiseasesShanghai Engineering Center for Visual Science and PhotomedicineShanghai Engineering Center for Precise Diagnosis and Treatment of Eye DiseasesShanghai 200080China Department of Ophthalmology Children’s Hospital of Fudan UniversityShanghai 201102China

●AIM:To identify the differential methylation sites(DMS)and their according genes associated with diabetic retinopathy(DR)development in type 1 diabetes(T1DM)children.●METHODS:This study consists of two surveys.A total of 40 T1DM children was included in the first *** no participant has DR,retina thinning was used as a surrogate indicator for *** lowest 25%participants with the thinnest macular retinal thickness were included into the case group,and the others were *** DNA methylation status was assessed by the Illumina methylation 850K array BeadChip assay,and compared between the case and control *** DMS with a potential role in diabetes were *** second survey included 27 T1DM children,among which four had *** methylation patterns of the four DMS identified by 850K were compared between participants with and without DR by pyrosequencing.●RESULTS:In the first survey,the 850K array revealed 751 sites significantly and differentially methylated in the case group comparing with the controls(|Δβ|>0.1 and Adj.Pranscription elongation regulator 1 like(TCERG1L,cg07684215)gene was hypermethylated in the four T1DM children with DR(P=0.018),which was consistent with the result from the first *** methylation status of the other three DMS(cg26389052,cg25192647,and cg05413694)showed no difference(all P>0.05)between participants with and without DR.●CONCLUSION:The hypermethylation of the TCERG1L gene is a risk factor for DR development in Chinese children with T1DM.

关键词： DNA methylation 850K array pyrosequencing diabetic retinopathy type 1 diabetes children

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关注青春期前矮身材儿童的早期诊断及干预

中国当代儿科杂志 2024年第6期26卷 553-558页

作者：苟鹏程昕然成都市妇女儿童中心医院儿童遗传与内分泌代谢科四川成都610073

我国青春期前儿童矮身材的发生率较高。尽早明确病因,及时进行干预,可为矮身材儿童带来更好的获益。该文对青春期前矮身材儿童的早期诊断、干预措施、个体化用药剂量等进行了概述,以期为临床医生提供参考。

关键词：矮身材青春期前早期诊断早期干预儿童

汉字注音特点与字典辞书文献来源考察——以《新撰字镜》注音从邪混切为例

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古汉语研究 2024年第1期 78-93,127页

作者：蔡欣然厦门大学中文系福建厦门361005

考察古代字典、辞书的文献来源,通常可以从形、音、义三个方面进行分析。相对于形体与释义而言,注音更具稳定性,因此汉字注音特点的认定是考察字典辞书文献來源的有效途径。《新撰字镜》大量参考《玄应音义》《玉篇》《切韵》等中土文献... 详细信息

考察古代字典、辞书的文献来源,通常可以从形、音、义三个方面进行分析。相对于形体与释义而言,注音更具稳定性,因此汉字注音特点的认定是考察字典辞书文献來源的有效途径。《新撰字镜》大量参考《玄应音义》《玉篇》《切韵》等中土文献,在字形、字音、字义以及词汇方面保存了大量已经散佚的文献资料,极具学术价值,而要充分利用这些资料,首先必须确定各个条目的文献来源。顾野王《玉篇》注音上普遍存在从邪混切的现象,据此可以推测《新撰字镜》相关条目是否来自《玉篇》。

关键词：字典辞书注音新撰字镜从邪混切

中国式现代化视角下中国铁矿石类大宗商品对外贸易定价权研究

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价格月刊 2024年第6期 11-18页

作者：云乐鑫潘信然青岛理工大学商学院山东青岛266520 波士顿大学大都会学院马萨诸塞波士顿02215

改革开放以来中国经济发展迅速,逐渐步入工业化中后期阶段,对各类大宗商品的需求与日俱增。在国际市场,中国作为全球大宗商品重要的贸易国与消费国,缺乏对大宗商品定价权的影响力,受大宗商品国际价格波动影响较大,在国际大宗商品贸易中... 详细信息

改革开放以来中国经济发展迅速,逐渐步入工业化中后期阶段,对各类大宗商品的需求与日俱增。在国际市场,中国作为全球大宗商品重要的贸易国与消费国,缺乏对大宗商品定价权的影响力,受大宗商品国际价格波动影响较大,在国际大宗商品贸易中较为被动。基于国际铁矿石贸易市场的基本现状,以铁矿石为切入点,分析了当前中国在国际大宗商品的定价权,根据国内大宗商品进口贸易情况,探讨了在国际贸易中中国大宗商品定价权缺失的原因,并提出了相关对策建议。

关键词：大宗商品铁矿石贸易定价权对外贸易