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Unconventional Organic Low-Dimensional Crystals:Diversity and Potential Applications

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CCS Chemistry 2024年第7期6卷 1628-1653页

作者： Jin feng Mao Sun Ying-xin Ma zhen-Yu Geng Chuan-Zeng Wang Shu-Ping Zhuo Shu-Hai Chen Hong-Tao {3.n Xue-Dong Wang school of Chemistry and Chemical Engineering Shandong University of TechnologyZibo 255000 school of Resources and environmental Engineering Shandong University of TechnologyZibo 255000 Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123

Organic low-dimensional crystals have garnered escalating interests in the realms of miniaturized optoelectronics and integrated *** continual expansion of molecular systems and improvement in experimental conditions have given rise to unconventional organic low-dimensional crystals,which showcase a variety of appealing structure-dependent properties in the realm of organic semiconductors,owing to their adaptable physicochemical characteristics and exceptional optoelectronics ***,the development of unconventional low-dimensional crystals is filled with abundant possibilities due to their diverse application ***,we present a comprehensive overview of advancements in research on representative cases of unconventional low-dimensional organic crystals,using a systematic and rational structural ***,we have also discussed the existing challenges and future directions,aspiring to deepen understanding and encourage further research exploration in this field.

关键词： organic semiconductor crystal growth precise synthesis noncovalent interaction integrat-ed photonics

Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions

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Chinese Journal of Integrative Medicine 2024年第6期30卷 565-576页

作者： KE Jun-yu SONG Jin-bin li Long HE zhen-fan HUANG Zhuo-jian liU zheng-lin CHEN Gui-rong WANG Hai-yan WEN Su-ru ZHOU Heng-li MA Hui-lin DU Qun WU Yong-qiang li Yan-wu CHEN xin-lin school of Basic Medical sciences Guangzhou University of Chinese MedicineGuangzhou510006China Department of Surgery II Gaozhou Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese MedicineGaozhou525200China science and Technology Innovation center Guangzhou University of Chinese MedicineGuangzhou510405China The First Clinical Medical College of Guangzhou university of Traditional Chinese Medicine Guangzhou510405China

Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass the classically activated pro-inflammatory M1 phenotype, as well as the alternatively activated anti-inflammatory M2 phenotype. In regular conditions, intestinal macrophages serve to shield the gut from inflammatory harm. However, when a combination of genetic and environmental elements influences the polarization of these macrophages, it can result in an M1/M2 macrophage activation imbalance, subsequently leading to a loss of control over intestinal inflammation. This shift transforms normal inflammatory responses into pathological damage within the intestines. In patients with ulcerative colitis-associated colorectal cancer (UC-CRC), disorders related to intestinal inflammation are closely correlated with an imbalance in the polarization of intestinal M1/M2 macrophages. Therefore, reinstating the equilibrium in M1/M2 macrophage polarization could potentially serve as an effective approach to the prevention and treatment of UC-CRC. This paper aims to scrutinize the clinical evidence regarding Chinese medicine (CM) in the treatment of UC-CRC, the pivotal role of macrophage polarization in UC-CRC pathogenesis, and the potential mechanisms through which CM regulates macrophage polarization to address UC-CRC. Our objective is to offer fresh perspectives for clinical application, fundamental research, and pharmaceutical advancement in UC-CRC.

关键词： macrophage ulcerative colitis colon cancer Chinese medicine

基于空间尺度效应的山东省PM_(2.5)浓度时空变化及空间分异地理探测

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环境科学 2024年第5期45卷 2596-2612页

作者：徐勇韦梦新邹滨郭振东李沈鑫中南大学地球科学与信息物理学院长沙410083 桂林理工大学测绘地理信息学院桂林541006

基于PM_(2.5)遥感数据,采用Theil-Sen Median趋势分析和Mann-Kendall显著性检验,分析2000~2021年山东省PM_(2.5)浓度时空变化特征,结合地理探测器,在省-市-县三级空间尺度上探测影响山东省PM_(2.5)浓度空间分异的影响因子影响力.结果表... 详细信息

基于PM_(2.5)遥感数据,采用Theil-Sen Median趋势分析和Mann-Kendall显著性检验,分析2000~2021年山东省PM_(2.5)浓度时空变化特征,结合地理探测器,在省-市-县三级空间尺度上探测影响山东省PM_(2.5)浓度空间分异的影响因子影响力.结果表明:①时间上,2000~2021年山东省ρ(PM_(2.5))均值在3..15~88.63.g·m^(−3.之间,略微高于《环境空气质量标准》中可吸入颗粒物的二级标准限值(3.μg·m^(−3.).在年际尺度上,2013.是ρ(PM_(2.5))变化的峰值年,其值为83.3.μg·m^(−3.,据此将山东省PM_(2.5)浓度变化趋势分为两个阶段:持续上升和快速下降阶段.在季节尺度上,PM_(2.5)浓度呈现“夏低冬高,春秋居中”分布特征和先降后升的“U”型变化规律.②空间上,山东省PM_(2.5)浓度呈现出“西高东低”的空间分布格局,PM_(2.5)浓度高值区分布山东省西部地区,低值区则分布在东部半岛地区.PM_(2.5)浓度空间变化趋势呈现显著的空间异质性,极显著下降的区域主要分布在东部半岛地区.③因子探测结果表明,气候因子是影响山东省PM_(2.5)浓度空间分异的重要影响因素,平均气温对山东省PM_(2.5)浓度空间分异的影响最高,q值为0.512.省-市-县多尺度探测结果显示,影响PM_(2.5)浓度空间分异的影响因子及其影响力在不同空间尺度上具有差异性.省级尺度上,平均气温、日照时数和坡度是影响PM_(2.5)浓度空间分异的主要影响因子;市级尺度上,降水、高程和相对湿度是影响PM_(2.5)空间分异的主要影响因子;县级尺度上,降水、平均气温和日照时数是影响PM_(2.5)浓度空间分异的主要影响因子.

关键词：山东省 PM_(2.5)浓度多尺度时空变化地理探测器影响因素

Inferring Mycobacterium Tuberculosis Drug Resistance and Transmission using Whole-genome Sequencing in a High TB-burden Setting in china

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Biomedical and environmental sciences 2024年第2期37卷 157-169页

作者： FAN Yu feng liU Dong xin CHEN Yi Wang OU Xi Chao MAO Qi Zhi YANG Ting Ting WANG Xi Jiang HE Wen Cong ZHAO Bing liU zhen Jiang ABUliMITI Maiweilanjiang AIHEMUTI Maimaitiaili GAO Qian ZHAO Yan lin Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS) School of Basic Medical SciencesShanghai Medical CollegeFudan UniversityShanghai 200032China National Tuberculosis Reference Laboratory Chinese Center for Disease Control and PreventionBeijing 102206China Hangzhou Red Cross Hospital Hangzhou 310005ZhejiangChina xinjiang Uygur Autonomous Region center for Disease Control and Prevention Urumqi 830026XinjiangChina Tuberculosis Dispensary of Kashgar Prefecture Kashgar 844099XinjiangChina

Objective china is among the 3. countries with a high burden of tuberculosis(TB)worldwide,and TB remains a public health *** Prefecture in the southern {3.jiang Autonomous Region is considered as one of the highest TB burden regions in ***,molecular epidemiological studies of Kashgar are *** A population-based retrospective study was conducted using whole-genome sequencing(WGS)to determine the characteristics of drug resistance and the transmission *** A total of 1,668 isolates collected in 2020 were classified into lineages 2(46.0%),3.27.5%),and 4(26.5%).The drug resistance rates revealed by WGS showed that the top three drugs in terms of the resistance rate were isoniazid(7.4%,124/1,668),streptomycin(6.0%,100/1,668),and rifampicin(3.3.,55/1,668).The rate of rifampicin resistance was 1.8%(23.1,290)in the new cases and 9.4%(3./3.0)in the previously treated *** resistance mutations were detected more frequently in lineage 2 strains than in lineage 3.or 4 strains,respectively:18.6%vs.8.7 or 9%,P3./1,668).Multivariate logistic analyses indicated that sex,age,occupation,lineage,and drug resistance were the risk factors for recent *** the low rate of drug resistance,drug-resistant strains had a higher risk of recent transmission than the susceptible strains(adjusted odds ratio,1.414;95%CI,1.023.1.954;P=0.03.).Among all patients with drug-resistant tuberculosis(DR-TB),78.4%(171/218)were attributed to the transmission of DR-TB *** Our results suggest that drug-resistant strains are more transmissible than susceptible strains and that transmission is the major driving force of the current DR-TB epidemic in Kashgar.

关键词： Mycobacterium tuberculosis Whole-genome sequencing(WGS) Transmission Drug resistance xinjiang

Does china's digital economy contribute to low-carbon transition?

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Ecological Economy 2024年第2期20卷 102-122页

作者： li Jun-jun HUANG xin-yu CHEN Mu ZHANG Meng-jiang ZHANG zhen school of Economics Fujian Normal UniversityFuzhou 350007CHINA College of Mechanical and Electrical Engineering Wuyi UniversityNanping 354300CHINA

The digital economy,as a new emerging economic form,has become an important power for realizing Chinese-style modernization and promoting green development in *** paper measures the digital economy and low-carbon transition index based on the data of 3. provinces in china from 2013.to 2020 and analyzes the mechanism and path of the digital economy affecting low-carbon transition using the fixed effect panel data model and the threshold effect *** is found that,(1)The digital economy and low-carbon transition in china are various in different regions,with characteristics of being unbalanced and insufficient.(2)The digital economy significantly promotes low-carbon transition,with the greatest influence in the Central region,followed by the Eastern region and the Western *** different dimensions,the development of informatization and digital transactions promote low-carbon transition,but the development of the internet plays an inhibiting role.(3.The higher the degree of urbanization and {3. regulation,the greater the influence of the digital economy on low-carbon transition.

关键词： digital economy low-carbon transition threshold effect model instrumental variables quantile regression

融合多源海洋大地测量数据的南海海底地形多层感知机反演

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地球物理学报 2024年第4期67卷 1368-1382页

作者：周帅刘新李真祝程程袁佳佳李静静郭金运孙和平山东科技大学测绘与空间信息学院青岛266590 山东建筑大学测绘地理信息学院济南250101 安徽理工大学空间信息与测绘工程学院安徽淮南232001 地理信息工程国家重点实验室西安710054 中国科学院精密测量科学与技术创新研究院武汉430077

本文融合SIO(Scripps Institution of Oceanography)发布的垂线偏差、重力异常和垂直重力梯度数据及NCEI(National centers for environmental Information)发布的船载测深数据,利用多层感知机神经网络(Multi-Layer Perceptron,MLP)建立南海海域(108°E—121°E,6°N—23.N)分辨率为1'×1'的海底地形模型(MLP_Depth).首先,将642716个船载测深控制点的位置信息与周围4'×4'格网点处的地球重力信息(垂线偏差、重力异常、垂直重力梯度)作为输入数据,将船载测深控制点处实测水深值作为输出数据,训练MLP神经网络模型,训练结束时决定系数R2为99%,平均绝对误差MAE为3..3. m.然后,将研究区域内1'×1'格网正中心点处的输入数据输入于MLP模型中,可得格网正中心点处的预测海深值.最后,根据预测海深值建立研究区域范围内分辨率为1'×1'的MLP_Depth模型.将MLP_Depth模型预测水深与160679个检核点处实测水深对比,其差值的标准差STD(75.3. m)、平均绝对百分比误差MAPE(5.89%)与平均绝对误差MAE(42.91 m)皆优于GEBCO_2021模型、topo_23.1模型、ETOPO1模型与检核点实测水深差值的STD(108.88 m、113.41 m、229.67 m)、MAPE(6.11%、6.94%、18.3.%)与MAE(47.3. m、52.24 m、13..08 m).同时,为了研究不同区域内利用该方法建立的海底地形模型的精度,本文在研究区域内分别建立了A、B区域的海底地形模型(MLP_Depth_A、MLP_Depth_B).经过验证得:MLP_Depth_A、MLP_Depth_B相比于MLP_Depth模型具有更高的精度,更能反应海底地形的变化趋势.

关键词：多层感知机海底地形南海垂线偏差重力异常垂直重力梯度

黄河(郑州段)水体中微塑料污染特征及来源分析

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中国环境科学 2024年第7期44卷 4136-4144页

作者：李和通马振芳郭宇邓正云李银月桂新马丽张发文河南省郑州生态环境监测中心河南郑州450007 河南农业大学河南郑州450046

为探究微塑料在我国黄河中下游水体中的分布情况和污染特征,以黄河(郑州段)为研究对象,选取7个具有代表性的点位采集水样,通过体视显微镜对微塑料的丰度和形貌特征进行观察,进一步借助显微红外光谱对其组成成分进行鉴定,并将统计结果与... 详细信息

为探究微塑料在我国黄河中下游水体中的分布情况和污染特征,以黄河(郑州段)为研究对象,选取7个具有代表性的点位采集水样,通过体视显微镜对微塑料的丰度和形貌特征进行观察,进一步借助显微红外光谱对其组成成分进行鉴定,并将统计结果与其他水体的微塑料污染状况进行对比分析,并探究其污染来源.结果表明:黄河(郑州段)水体中微塑料平均丰度为(16.86±4.20)n/L;以粒径小于1mm的尺寸为主,占比高达61.42%;形状中纤维状占比最高为79.3.%;微塑料颜色以透明为主,占比为56.06%;微塑料聚合物类型以人造丝(Rayon)为主,同时还有聚对苯二甲酸乙二醇酯(PET)和聚丙烯(PP)等.不同点位微塑料的形貌特征和聚合物类型可在一定程度上反映其潜在污染来源.黄河(郑州段)和其他水体相比,微塑料丰度分布存在一定的差异性,粒径分布趋势则大致相同,形状、颜色以纤维状、透明为主,不同水体间的微塑料污染差异可能与水体周边生境、经济水平以及人类活动情况等因素密切相关.

关键词：微塑料污染特征黄河丰度分布

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好氧堆肥污泥农用后溶解性有机质释放特征

光谱学与光谱分析 2024年第4期44卷 1011-1017页

作者：时聪慧张瑞昌朱书法李欣彤周新全张宁荣亮杨丽珍魏学锋河南科技大学化学化工学院河南洛阳471023 有色金属新材料与先进加工技术省部共建协同创新中心河南洛阳471023 中国五洲工程设计集团有限公司北京100053

研究污泥农用后溶解有机质(DOM)的释放特征,有助于评价和预测土壤中共存污染物的环境行为和效应。以河南省洛阳市某污泥处理厂好氧堆肥后的市政污泥作为样本,利用扫描电子显微镜(SEM)、总有机碳分析仪、紫外-可见吸收光谱(UV-Vis)、凝... 详细信息

研究污泥农用后溶解有机质(DOM)的释放特征,有助于评价和预测土壤中共存污染物的环境行为和效应。以河南省洛阳市某污泥处理厂好氧堆肥后的市政污泥作为样本,利用扫描电子显微镜(SEM)、总有机碳分析仪、紫外-可见吸收光谱(UV-Vis)、凝胶渗透色谱(GPC)、三维荧光光谱(3.-EEM)、傅里叶变换红外光谱(FTIR)和核磁共振波谱(NMR)等表征技术,研究污泥农用后释放DOM的浓度、分子量、组成和结构等性质的演变特征。结果表明,污泥还田60 d内,释放的DOM微观形貌上存在较大变化,由致密块状物变为不规则松散物质;污泥农用后释放溶解性有机碳(DOC)量在4.25~6.22 mg·g^(-1)污泥范围,呈现先上升后稳步下降的趋势;释放过程中,污泥DOM的分子量和芳香性等性质也存在显著的变化:污泥DOM重均分子量由0.5 d时2674 g·mol^(-1)的逐渐升高为60 d的129026 g·mol^(-1);污泥还田后释放的DOM分子中芳香性物质逐渐积累;3.-EEM结合平行因子分析(PARAFAC)模型分析污泥释放DOM中的荧光物质,发现DOM中荧光物质主要为类富里酸和类腐殖质,释放过程中,类腐殖质逐渐积累,DOM整体上呈现腐殖化趋势;FTIR图谱表征污泥DOM脂肪族烷烃类物质的减少和芳香烃物质生成。污泥还田后释放DOM数量和性质变化,显著改变土壤中共存污染物环境行为和生态效应。该研究可为评估和预测污泥农用后产生的环境影响提供理论依据,也对市政污泥的资源化利用具有一定指导意义。

关键词：污泥农用溶解性有机质释放特征分子量芳香性

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琥珀酸改性天然竹纤维吸附镉/铅的行为机制

中国环境科学 2024年第8期44卷 4380-4388页

作者：张晓峰李相雨王鑫胡晶香马振宇谭峰亮何璐湖南人文科技学院材料与环境工程学院湖南娄底417000 精细陶瓷与粉体材料湖南省重点实验室湖南娄底417000 北京中农博后农业科学研究院北京100193

天然竹纤维经碱化、酸化等预处理后,与琥珀酸发生行酯化连接反应,制得改性竹纤维.通过红外光谱(FTIR)与扫描电镜(SEM)分析可知,改性后竹纤维中电负性的羧基和酯基增加,其微观结构也由致密平整变为褶皱多孔.吸附实验结果表明,相较于天然... 详细信息

天然竹纤维经碱化、酸化等预处理后,与琥珀酸发生行酯化连接反应,制得改性竹纤维.通过红外光谱(FTIR)与扫描电镜(SEM)分析可知,改性后竹纤维中电负性的羧基和酯基增加,其微观结构也由致密平整变为褶皱多孔.吸附实验结果表明,相较于天然竹纤维,其改性后对溶液中镉(Cd)、铅(Pb)的吸附率均明显提高(分别可达47.3.%和44.57%以上),且能适用于更宽pH值范围.改性和未改性竹纤维对Cd和Pb的吸附反应既符合Langmuir热力学模型又符合Freundlich热力学模型.且由Langmuir等温方程计算可知,改性后的竹纤维对Cd和Pb的最大吸附容量(Q_(m))分别由8.9687mg/g和11.5075mg/g提高到26.1780mg/g和3..3.25mg/g.这说明琥珀酸的改性过程增加了竹纤维吸附位点,从而提高了其对Cd/Pb的吸附能力,可为生物吸附材料的改性升级提供新思路.

关键词：琥珀酸竹纤维酯化改性镉铅