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Effect of nucleating agents on the electrical properties of cross-linked polyethylene under tensile stress

High Voltage 2024年第2期9卷 429-439页

作者： Yunqi Xing Jiahao Liu Jingang Su Junwei Zha Guochang Li Ze Guo xiaozhen zhao Mengjia Feng State Key Laboratory of Reliability and Intelligence of Electrical Equipment Hebei University of TechnologyTianjinChina Electric Power Research Institute of State Grid Hebei Electric Power Supply Co. Ltd.ShijiazhuangChina Beijing Advanced Innovation Center for Materials Genome Engineering School of Chemistry and Biological EngineeringUniversity of Science&Technology BeijingBeijingChina Institute of Advanced Electrical Materials Qingdao University of Science and TechnologyQingdaoChina

During the operation of high-voltage cables,external stress and residual stress can affect the aggregated structure of insulating materials and lead to significant deterioration in their electrical *** investigate the evolution characteristics of the electrical properties of cross-linked polyethylene(XLPE)under mechanical stress,this paper ex-plains the relationship between the aggregated structure of XLPE and its electrical properties and proposes a method for improving insulation performance under me-chanical *** results show that metallocene polyethylene used as a nucleating agent can promote crystallisation through heterogeneous nucleation and increase Young's modulus by non-uniform nucleation,increasing crystallinity and reducing interplanar spacing,resulting in more complete crystal forms and reduced damage to the aggregated structure during the tensile *** nucleating agent modification,the XLPE crystallisation becomes more uniform,and interfacial adhesion forces *** weakened interface damage process between the amorphous and crystalline regions under tensile stress effectively inhibits the process of molecular chain polarisation turning and reduces trap *** modified XLPE crystal structure shows a tendency towards densification and enhanced molecular chain interactions,which can reduce the damage to the aggregated structure under tensile stress,while the reduced free volume inside the material and the shortened average free path of carriers can weaken the damage of high-energy electrons to molecular chains,thereby inhibiting the process of electrical tree *** results show that nucleating agents have great potential for maintaining the stable operation of XLPE cables under mechanical stress.

关键词： stress electrical damage

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Long noncoding nuclear enriched abundant transcript 1_2 is a promising biomarker for childhood-onset systemic lupus erythematosus

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Pediatric Investigation 2024年第2期8卷 101-107页

作者： Shipeng Li Xia Wang xiaozhen zhao Jianghong Deng Weiying Kuang Junmei Zhang Xiaohua Tan Chao Li Caifeng Li Department of Rheumatology Beijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijingChina Center for Infectious Diseases Beijing Youan HospitalCapital Medical UniversityBeijing Key Laboratory for HIV/AIDS ResearchBeijingChina

Importance:Systemic lupus erythematosus(SLE)is a diffuse connective tissue disease with complex clinical manifestations and prolonged *** early diagnosis and condition monitoring of SLE are crucial to disease ***:To assess the diagnostic value of long noncoding RNA(lncRNA)nuclear enriched abundant transcript 1(NEAT1)in childhood-onset SLE(cSLE).Methods:Fifty-seven children diagnosed with SLE,40 children diagnosed with juvenile idiopathic arthritis(JIA),and 40 healthy children were *** blood samples from each patient were collected.A quantitative polymerase chain reaction was used to confirm the expression of lncNEAT1_1 and lncNEAT1_2 in peripheral *** among parameters were analyzed using the Mann-Whitney U test or independent sample ***:The expression of both lncNEAT1_1 and lncNEAT1_2 in patients with cSLE were significantly higher than that of healthy control and patients with *** operating characteristic curves revealed an area under the curve(AUC)of 0.633(95%confidence interval[CI],0.524-0.742;P=0.024)for lncNEAT1_*** AUC of lncNEAT1_2 was 0.812(95%CI,0.727-0.897;P<0.0001)to discriminate individuals with cSLE from health control and children with JIA with a sensitivity of 0.622 and a specificity of ***,lncNEAT1_2 expression was higher in patients with cSLE presenting with fever,lupus nephritis,elevated erythrocyte sedimentation rate,active disease activity,and decreased C3 level,compared with those without these ***,no similar correlation was observed for lncNEAT1_***:The expression of lncNEAT1_2 was significantly elevated in children with SLE,especially those with fever,renal involvement,and low C3 *** findings suggest that lncNEAT1_2 may represent a potential biomarker for cSLE.

关键词： Biomarker Children LncRNA SLE NEAT1

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Blau syndrome with incidental multiple enchondromatosis

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Rheumatology & Autoimmunity 2024年第3期4卷 183-185页

作者： xiaozhen zhao Junmei Zhang Weiying Kuang Jianghong Deng Xiaohua Tan Chao Li Shipeng Li Caifeng Li Department of Rheumatology Beijing Children's HospitalCapital Medical UniversityNational Centre for Children's HealthBeijingChina Department of Nephrology and Rheumatology Children's Hospital Affiliated to Zhengzhou UniversityZhengzhouHenanChina Department of Nephrology and Rheumatology Henan Children's Hospital Zhengzhou Children's HospitalZhengzhouHenanChina

To the Editor,Blau syndrome(BS)is a rare autosomal dominant disorder that occurs early in *** is caused by mutations in nucleotide-binding oligomerization domain-containing protein 2(NOD2),also known as caspase activation and recruitment domain 15(CARD15).NOD2 mutations result in the activation of nuclear factor-kappa B and induction inflammation.1 Some patients develop the disease in a familial manner,but sporadic cases can *** main clinical manifestations of BS are the triad of rash,arthritis,and iridocyclitis,while multiple aortitis,deafness,heart disease,liver,spleen,and central nervous system are also involved.2 The disease was first described by *** in 1985.

关键词： NOD2 spleen clinical

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Anatomy of the perirectal fascia at the level of rectosacral fascia revisited

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Gastroenterology Report 2022年第1期10卷 243-250页

作者： Waleed M.Ghareeb Xiaojie Wang Pan Chi Zhifang Zheng xiaozhen zhao Department of Colorectal Surgery The Affiliated Union Hospital of Fujian Medical UniversityFuzhouFujianP.R.China Department of General and Gastrointestinal Surgery Suez Canal UniversityIsmailiaEgypt Laboratory of Clinical Applied Anatomy Department of Human AnatomyHistologyand EmbryologyFujian Medical UniversityFuzhouFujianP.R.China

Background:The relative anatomical understanding of the perirectal fasciae is of paramount importance for the proper performance of total mesorectal excision(TME).This study was to demonstrate the planes of TME and validates the intraoperative findings using cadaveric ***:In this combined retrospective and prospective study,bilateral attachment of the rectosacral fascia(RSF)was observed in 28 cadaveric specimens(male,n=14;female,n=14).From January 2018 to December 2019,surgical videos of 67 patients who underwent laparoscopic TME at the Affiliated Union Hospital of Fujian Medical University(Fuzhou,China)were reviewed and interpreted with the cadaveric ***:The RSF(synonym:Waldeyer’s fascia)is the end of the pre-hypogastric fascia at the level of S4 and comprises two layers(upper and lower).These two layers provide double fascial protection for the venous sacral *** inserts into the fascia propria of the rectum along a broad horizontal arc that merges anterolaterally in an oblique downward direction until it meets the posterolateral merge of Denonvilliers’fascia at the lateral rectal ligament(LRL).This ligament does not look like a true ligament but is more likely to be a fascial combination that cushions the rectal innervation and middle rectal ***:Understanding the lateral attachment of RSF and its contribution to LRL provides invaluable surgical guidance to dissect this critical ***,lateral dissection is proposed from the anterior to the posterior direction to find the correct plane that guarantees an intact mesorectal envelope to protect the important nearby nerve structures.

关键词： laparoscopy anatomy rectum fascia rectal neoplasms

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New Rural Community Construction or Retention Development:A Comparative Analysis of Rural Settlement Transition Mechanism in Plain Agriculture Area of China Based on Actor Network Theory

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Chinese Geographical Science 2024年第3期34卷 436-452页

作者： QU Yanbo DONG xiaozhen MA Wenqiu zhao Weiying School of Public Administration and Policy Shandong University of Finance and EconomicsJinan 250014China Institute of Land Science and Policy Shandong University of Finance and EconomicsJinan 250014China College of Engineering China Agricultural UniversityBeijing 100083China

It is an important way to realize rural revitalization and sustainable development to guide rural settlement transition(RST)in an appropriate *** paper uses actor network theory(ANT)to construct a theoretical framework for the study of *** two typical villages with different transition paths in rural areas of North China Plain as examples,this paper reveals the mechanism of RST and makes a comparative *** results show that:1)after identifying problems and obligatory passage point,key actors recruit heterogeneous actors into the actor network by entrusting them with common interests,and realize RST under the system operation.2)Rural settlements under different transition paths have similarities in the problems to be solved,collective actions and policy factors,but there are differences in the transition process,mechanism and *** actor network and mechanism of RST through the path of new rural community construction are more complex and the transition effect is more *** contrast,the degree of RST of retention development path is limited if there is no resource and location advantage.3)Based on the applicable conditions of different paths,this paper designs a logical framework of‘Situation-Structure-Behavior-Result’to scientifically guide the identification of RST paths under the background of rural revitalization.

关键词： rural settlement transition(RST) actor network theory(ANT) transition path transition mechanism plain area China

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川蜀“中衷参西”妇科流派治疗妇科痛症临床用药分析

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四川中医 2024年第7期42卷 17-22页

作者：杨君君赵晓贞谭兴民林青孙青凤陈淑涛四川省中西医结合医院四川成都610041

本文通过研究川蜀“中衷参西”妇科流派传承人陈淑涛主任诊治妇科痛症的临床病例,总结出川蜀“中衷参西”妇科流派治疗妇科痛症的临床经验及用药规律。选取2020年1月1日~2022年12月31日,就诊于四川省中西医结合医院妇科门诊陈淑涛主任... 详细信息

本文通过研究川蜀“中衷参西”妇科流派传承人陈淑涛主任诊治妇科痛症的临床病例,总结出川蜀“中衷参西”妇科流派治疗妇科痛症的临床经验及用药规律。选取2020年1月1日~2022年12月31日,就诊于四川省中西医结合医院妇科门诊陈淑涛主任处痛症患者。3年门诊量共27739,其中痛症就诊次数共6441,就诊人次共2770人次。利用Excel表及相关程序,挖掘出陈淑涛主任对于妇科痛症的诊断、检查方法、辨证分析、处方用药的经验,重点分析临床用药的频率频次、常用药对等临床经验。结果:陈淑涛主任辨治妇科痛症多从“湿热瘀结”入手,顺应女性月经周期,月经期多活血通经,多采用自拟方“三川汤”加减,非月经期多清热利湿,活血化瘀,多采用自拟方“白莲散结汤”加减。

关键词：川蜀“中衷参西” 妇科流派妇科痛症经验

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贵州不同产区蜂糖李果实糖酸组分差异及品质评价

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贵州农业科学 2024年第8期52卷 84-93页

作者：王红林解璞马玉华赵凯王红赵晓珍郑乾明贵州省果树科学研究所贵州贵阳550006 贵州省农业科学院贵州贵阳550006 贵州省农业科学院农业农村部喀斯特山区作物基因资源与种质创新重点实验室贵州贵阳550006

【目的】探明贵州不同产区蜂糖李果实的糖酸品质特征,为提高蜂糖李果品质量整体水平和促进产业可持续发展提供参考。【方法】以贵州安顺4个种植区(AZNL、AZND、AZNJ和AZYH)、黔南州3个种植区(QNLF、QNLM和QNHD)以及贵阳(GXFS)、黔西南州... 详细信息

【目的】探明贵州不同产区蜂糖李果实的糖酸品质特征,为提高蜂糖李果品质量整体水平和促进产业可持续发展提供参考。【方法】以贵州安顺4个种植区(AZNL、AZND、AZNJ和AZYH)、黔南州3个种植区(QNLF、QNLM和QNHD)以及贵阳(GXFS)、黔西南州(QXQG)、铜仁市(TYHG)和遵义市(ZSYX)种植的蜂糖李新鲜成熟果实为材料,考察果形指数和硬度等外观品质,检测分析果实糖酸组分及含量、可溶性固形物和可滴定酸含量等主要风味指标,并对果品品质22个指标进行主成分分析和系统聚类分析。【结果】11份蜂糖李果实糖含量为102.29~160.71 mg/g,糖组分以蔗糖含量最高,平均56.21 mg/g,山梨醇含量最低,仅20.71 mg/g;有机酸含量为5.29~7.89 mg/g,有机酸组分以苹果酸含量最高,平均达5.31 mg/g,抗坏血酸含量最低,仅0.04 mg/g。主成分分析共提取5个主成分,累积贡献率达92.89%,获得品质评价函数:F=0.361 F_(1)+0.241 F_(2)+0.153 F_(3)+0.107 F_(4)+0.066 F5。聚类分析显示,QXQG和AZNL各为一类,其余9个样品聚为一类,其中,AZNL和QXQG综合得分较高,品质最佳。【结论】贵州11份不同种植区蜂糖李果实品质依次为AZNL> QXQG> QNLF> AZNJ> AZND> QNLM> AZYH> QNHD> GXFS> ZSYX>TYHG。

关键词：蜂糖李糖组分酸组分品质评价果形指数果实硬度可溶性固形物可滴定酸

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系统性红斑狼疮低疾病活动度及缓解状况的真实世界研究

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北京大学学报（医学版） 2024年第2期56卷 273-278页

作者：任立敏赵楚楚赵义周惠琼张莉芸王友莲沈凌汛范文强李洋厉小梅王吉波程永静彭嘉婧赵晓珍邵苗李茹北京大学人民医院风湿免疫科北京100044 首都医科大学宣武医院风湿免疫科北京100053 解放军总医院第四医学中心风湿免疫科北京100142 山西大医院风湿免疫科太原030032 江西省人民医院风湿免疫科南昌330006 华中科技大学协和医院风湿免疫科武汉430022 新乡医学院附属中心医院风湿免疫科河南新乡453099 哈尔滨医科大学附属第二医院风湿免疫科哈尔滨150001 安徽省立医院风湿免疫科合肥230001 青岛大学附属医院风湿免疫科山东青岛266000 北京医院风湿免疫科北京100730

目的:研究系统性红斑狼疮(systemic lupus erythematosus, SLE)患者的真实世界低疾病活动度和临床缓解率,并分析其相关因素。方法:采用现场调查的研究方法,对国内11家医院1 000例SLE患者进行问卷调查,记录患者的一般资料、临床表现、实... 详细信息

目的:研究系统性红斑狼疮(systemic lupus erythematosus, SLE)患者的真实世界低疾病活动度和临床缓解率,并分析其相关因素。方法:采用现场调查的研究方法,对国内11家医院1 000例SLE患者进行问卷调查,记录患者的一般资料、临床表现、实验室检查结果和治疗情况等。采用狼疮低疾病活动状态(lupus low disease activity state, LLDAS)和SLE缓解定义(definitions of remission in SLE,DORIS)评价患者低疾病活动度和临床缓解率,进一步分析符合LLDAS或DORIS缓解患者的临床特征。多因素Logistic回归分析影响LLDAS或DORIS缓解的相关因素。结果:1 000例SLE患者中,207例(20.7%)符合LLDAS标准,104例(10.4%)符合DORIS缓解。与不符合LLDAS或DORIS的患者相比,符合LLDAS或DORIS者高收入比例更高,病程更长,贫血、肌酐升高、红细胞沉降率增快和低白蛋白血症的发生率更低。应用羟氯喹>12个月或免疫抑制剂≥6个月的SLE患者缓解比例较高。多因素Logistic回归分析发现,红细胞沉降率增快、抗双链DNA抗体阳性、低补体血症(C3和C4)、蛋白尿及家庭收入低是不利于达到LLDAS或DORIS缓解的独立相关因素,而应用羟氯喹>12个月为达到LLDAS或DORIS缓解的保护因素。结论:SLE患者达到LLDAS或DORIS缓解状态的比例较低,规范应用羟氯喹和免疫抑制剂有助于患者的病情缓解。

关键词：系统性红斑狼疮缓解狼疮低疾病活动状态

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The“terminal line”:a novel sign for the identification of distal mesorectum end during TME for rectal cancer

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Gastroenterology Report 2022年第1期10卷 468-475页

作者： Waleed M.Ghareeb Xiaojie Wang xiaozhen zhao Meirong Xie Sameh H.Emile Sherief Shawki Pan Chi Department of Colon and Rectal Surgery Union Hospital of Fujian Medical UniversityFuzhouFujianP.R.China Department of Surgery Faculty of MedicineSuez Canal UniversityIsmailiaEgypt Department of Colon and Rectal Surgery Mayo ClinicRochesterMNUSA Laboratory of Clinical Applied Anatomy Fujian Medical UniversityFuzhouFujianP.R.China Basic Medical College Fujian Medical UniversityFuzhouFujianP.R.China Department of Colorectal Surgery Cleveland Clinic FloridaWestonFLUSA Colorectal Surgery Unit General Surgery DepartmentMansoura University HospitalsMansouraEgypt

Background:Although the clinical importance of complete,intact total mesorectal excision(TME)is the widely accepted standard for decreasing local recurrence of rectal cancer,the residual mesorectum still represents a significant component of resection margin *** study aimed to use a visible intraoperative sign to detect the distal mesorectal end to ensure complete inclusion of the mesorectum and avoid unnecessary ***:The distal mesorectum end was investigated retrospectively through a review of 124 operative videos at the Union Hospital of Fujian Medical University(Fujian,China)and Cleveland Clinic(Ohio,USA)by two independent surgeons who were blinded to each ***,28 cadavers and 44 post-operative specimens were prospectively examined by hematoxylin and eosin(H&E)staining and Masson’s staining to validate and confirm the findings of the retrospective *** and multivariate analyses were carried out to detect the independent factors that can affect the visualization of the distal mesorectal ***:The terminal line(TL)is the distal mesorectal end of the transabdominal and transanal TME(taTME)and appears as a remarkable pearly white fascial structure extending posteriorly from 2 to 10 o’*** examination revealed that the fascia propria of the rectum merges with the presacral fascia at the TL,beyond which the mesorectum ends,with no further downward *** the retrospective observation,the TL was seen in 56.6%of transabdominal TME and 56.0%of taTME *** approach and tumor distance from the anal verge were the independent variables that directly influenced the detection of the TL(P=0.03 and P=0.01).Conclusion: The TL is a visible sign where the transabdominal TME should end and the taTME should begin. Recognitionof the mesorectal end may impact the certainty of complete mesorectum inclusion. Further clinical trials are needed toconfirm the preliminary findings.

关键词： rectal cancer total mesorectal excision taTME TAMIS laparoscopy robotic

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Cultural Connotation of Landscape Plants and Its Expression in Landscape Design

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International Journal of Technology Management 2013年第7期 94-96页

作者： Huirong zhao xiaozhen Song Suzhou Art & Design Technology Institute Suzhou City Jiangsu Province 215104 China

This paper analyzes and summarizes the historical humanity significance of plants of personality, culture and auspicious symbol reflected in gardens and the expression methods of landscape plants in modern landscape d... 详细信息

关键词： landscape plants cultural connotation landscape design

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