检索结果-南通市图书馆

Chinese Medical Journal 2022年第19期135卷 2380-2382页

作者： Yuhao Sun xiaoyu Wen Zhuoxian Li Lijing Xu Meng Xia School of Basic Medicine Guangxi University of Chinese MedicineNanningGuangxi 530200China.

To the Editor:Vascular dementia(VD)is a clinical disease characterized_by cognitive dysfunction and intellectual decline caused byvarious cerebrovascularfactors.The high incidence of VD in middle-aged and elderly people has become a major medical and social problem worldwide.li Since its specific pathogenesis has not been fully elucidated,clinical practice is stillfocused on improving cognition and sAylmteprntoamtivaetilcy,t rweiathtm heignht,seuffcehc taivse pnierascse atanmd faenwd sdidoen eepffeezcitl.s2,i traditional Chinese medicine has drawn medical attention and become a hotspot in the medical research field.

关键词： decoction clinical pathogenesis

维普期刊数据库

A machine learning surrogate modeling benchmark for temperature field reconstruction of heat source systems

在线全文

学校读者我要写书评

暂无评论

Science China(Information Sciences) 2023年第5期66卷 162-181页

作者： Xiaoqian CHEN Zhiqiang GONG xiaoyu ZHAO Weien ZHOU wen YAO Defense Innovation Institute Chinese Academy of Military Science

The temperature field reconstruction of heat source systems(TFR-HSS) with limited monitoring sensors in thermal management plays an important role in the real-time health detection systems of electronic equipment in engineering. However, prior methods with common interpolations usually cannot provide accurate reconstruction performance as required. In addition, no public dataset exists for the wide research of reconstruction methods to further boost reconstruction performance and engineering applications. To overcome this problem, this work develops a machine learning surrogate modeling benchmark for the TFRHSS task. First, the TFR-HSS task is mathematically modeled from a real-world engineering problem, and four types of computational modelings are constructed to transform the problem into discrete mapping forms.Then, this work proposes a set of machine learning surrogate modeling methods, including general machine learning methods and deep learning methods, to advance the state-of-the-art methods over temperature field reconstruction. More importantly, this work develops a novel benchmark dataset, namely the temperature field reconstruction dataset(TFRD), to evaluate these machine learning surrogate modeling methods for the TFR-HSS task. Finally, a performance analysis of typical methods is given on the TFRD, which can serve as the baseline results on this benchmark.

关键词： temperature field reconstruction heat-source systems computational modeling temperature field reconstruction dataset machine learning surrogate modeling deep learning

Wide Band Gap Non-Fullerene Small Molecular Acceptors Containing Spirobifluorene and Benzotriazole with Three Different End-Capped Groups for P3HT-Based Organic Solar Cells

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2018年第5期36卷 392-398页

作者： xiaoyu Wen Bo Xiao Ailing Tang Junyi Hu Chunhe Yang Erjun Zhou Department of Chemistry School of Science Beijing Jiaotong University Beijing 100044 China CAS Key Laboratory of Nanosystem and Hierarchical Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Beijing 100190 China University of Chinese Academy of Sciences Beijing 200049 China

Spirofluorene （SF） and benzo[d][1,2,3]triazole （BTA） have been considered as promising building blocks to construct n-type photovoltaic materials. Herein, three new small molecule acceptors （SMAs） named BTA21, BTA23 and BTA27 with the structure of A2=A1-D-AI^A2 have been designed, in which SF and BTA were used as a central unit of D and bridged acceptor unit of A1, respectively. In addition, 3-ethylrhodanine, 2-（3-ethyl-4-oxothiazolidin-2-ylidene）malononitrile and malononitrile were chosen as terminal acceptor units to modulate the properties of the final SMAs. Three SMAs show wide optical band gaps （Eg） of 2.19, 2.15 and 2.22 eV, respectively, with gradually down-shift of the lowest unoccupied molecular orbital {LUMO） levels in the order of BTAZl, BTA23 and BTA27 depending on the electron-withdrawing capability of terminal acceptor units. BTA21 shows great advantages with respect to donor poly（3-hexylthiophene）（P3HT） over BTA23 and BTA27, such as well energy-level matching, complementary absorption and proper morpholgy, Concequently, P3HT：BTA21 shows the best power conversion efficiency （PCE） value of 3.28% with an open-circuit voltage （Voc） of 1.02 V, a short-circuit current （Jsc） of 5.45 mA.cm-2 and a fill factor （FF） of 0.59. These results indicate that the terminal acceptor group end-capped in SMAs plays a significant role in controlling their optical, electronic, and photovoltaic properties.

关键词： benzotriazole organic photovoltaic P3HT small molecular acceptor wide band gap

Analysis of sleep in individual Drosophila melanogaster reveals a self-regulatory role for cuticular hydrocarbons pheromones

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2022年第6期29卷 1737-1746页

作者： xiaoyu Wu Su Wang Xianguo Zhao Jing wen Yahong Li Zhangwu Zhao Juan Du Department of Entomology MOA Key Lab of Pest Monitoring and Green ManagementCollege of Plant ProtectionChina Agricultural UniversityBeijingChina

It is well established that pheromones are used by insects to transmit infor-mation between individuals.However,research has revealed that individual insects can be both the sender and the receiver of some pheromonal signals.It is therefore interesting to consider whether the pheromonal state of an individual insect can exert an effect on itself.In this study,we monitored the sleep activity of single flies exhibiting a mutation that leads to pheromonal deficiency and found that cuticular hydrocarbons(CHs)exerted self-regulatory effects on the amount of sleep experienced by these flies.To identify the physiological significance of this mechanism,we compared the amounts of sleep in in-dividual young flies and individual old flies(flies are known to sleep less as they get older)and compared this data with young and old flies exhibiting mutations that lead to CH reception defects.The differences in the amount of sleep experienced by young and old mutant flies were significantly lower than those of the control flies.Our data show that hydrocarbon signals produced by the cuticle in Drosophila can be self-perceived and regulate the amount of sleep acquired in a maturation-dependent manner.

关键词： cuticular hydrocarbons pheromone sleep

Implementation of sinh method in integration space forboundary integrals with near singularity in potential problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Mechanical Engineering 2016年第4期11卷 412-422页

作者： Guizhong XIE Dehai ZHANG Jianming ZHANG Fannian MENG wenliao DU xiaoyu Wen Mechanical and Electrical Engineering Institute Zhengzhou Universityof Light Industry Zhengzhou 450002 China State Key Laboratory forManufacturing Systems Engineering Xi'an Jiaotong University Xi'an710049 China State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body College of Mechanical and Vehicle Engineering HunanUniversity Changsha 410082 China

As a widely used numerical method, boundary element method (BEM) is efficient for computer aided engineering (CAE). However, boundary integrals with near singularity need to be calculated accurately and efficiently to implement BEM for CAE analysis on thin bodies successfully. In this paper, the distance in the denominator of the fundamental solution is first designed as an equivalent form using approximate expansion and the original sinh method can be revised into a new form considering the minimum distance and the approximate expansion. Second, the acquisition of the projection point by Newton-Raphson method is introduced. We acquire the nearest point between the source point and element edge by solving a cubic equation if the location of the projection point is outside the element, where boundary integrals with near singularity appear. Finally, the subtriangles of the local coordinate space are mapped into the integration space and the sinh method is applied in the integration space. The revised sinh method can be directly performed in the integration element. A verification test of our method is proposed. Results demonstrate that our method is effective for regularizing the boundary integrals with near singularity.

关键词： computer aided engineering (CAE) boundary element method (BEM) near singularity sinh method coordinate transformation integration space

Ultrafine Pt nanoparticles supported on double-shelled C/TiO2 hollow spheres material as highly efficient methanol oxidation catalysts

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2020年第10期29卷 275-282页

作者： xiaoyu Yue Yuguang Pu wen Zhang Ting Zhang Wei Gao Department of Chemical and Materials Engineering the University of AucklandPrivate Bag 92019Auckland 1142New Zealand

Catalyst support is extremely important for future fuel cell devices.In this work,we developed doubleshelled C/TiO2(DSCT)hollow spheres as an excellent catalyst support via a template-directed method.The combination of hollow structure,TiO2 shell and carbon layer results in excellent electron conductivity,electrocatalytic activity,and chemical stability.These uniformed DSCT hollow spheres are used as catalyst support to synthesize Pt/DSCT hollow spheres electrocatalyst.The resulting Pt/DSCT hollow spheres exhibited high catalytic performance with a current density of 462 mA mg^-1 for methanol oxidation reaction,which is 2.52 times higher than that of the commercial Pt/C.Furthermore,the increased tolerance to carbonaceous poisoning with a higher If/Ibratio and a better long-term stability in acid media suggests that the DSCT hollow sphere is a promising C/TiO2-based catalyst support for direct methanol fuel cells applications.

关键词： Catalyst support C/TiO2 hollow sphere Metal-support interactions Methanol oxidation reaction

维普期刊数据库

Electro-Deposition Pt Catalysts Supported on Carbon-Nanotubes for Methanol Oxidation

在线全文

学校读者我要写书评

暂无评论

Journal of Harbin Institute of Technology(New Series) 2015年第5期22卷 85-88页

作者： Hailin Song Peixia Yang xiaoyu Wen Maozhong An Jinqiu Zhang Chemical Engineering Institute Harbin Institute of Technology

In order to study the properties of supporting Pt catalysts for methanol oxidation,carbon-nanotubes are used by electrochemical deposition method. Different deposition turns,different cyclic voltammetry scanning speeds and processing time with ascorbic acid are investigated in this paper. The micrographs of Pt / CNTs catalysts are characterized by scanning electron microscopy,the electro-catalytic properties of Pt / CNTs catalysts for methanol oxidation are investigated by cycle voltammetry and chronoamperometry. The results show that the size of platinum will be greater with the faster scanning speed. After dissolution in ascorbic acid,Pt nanoparticles disperse uniformly. The obtained Pt / CNTs catalysts show a high electro-catalytic activity and stability.

关键词： Carbon nanotube Pt catalyst Cyclic voltammetry Ascorbic acid

维普期刊数据库

Carbon dots-based fluorescence sensor for two-photon imaging of pH in diabetic mice

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2023年第3期17卷 298-306页

作者： Li Yang Mengqi Wang xiaoyu Gu Wei Zhang Ping Li wen Zhang Hui Wang Bo Tang College of Chemistry Chemical Engineering and Materials ScienceCollaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of ShandongKey Laboratory of Molecular and Nano ProbesMinistry of EducationInstitute of Biomedical SciencesShandong Normal UniversityJinan 250014China

Herein,a reversible pH fluorescent sensor was developed using caffeic acid as the precursor by one-step solvothermal synthesis method.The carbon dots-based sensor(CA-CDs)exhibited pH-dependent increase in fluorescence intensity and showed linear relationship in the range of pH 6.60 and 8.00.Notably,the fluorescence sensor has a reversible response to pH change.Finally,the CA-CDs has been successfully applied for two-photon imaging of the pH in liver and kidney of diabetic mice.Imaging results showed that the pH value in kidney of diabetic mice was lower than that of the normal mice,while the pH value in liver of diabetic mice was almost the same as that of the normal mice.The present study provides a simple analytical method for pH detection suitable for in vivo.

关键词： carbon dots two-photon imaging pH diabetic mice

Topology optimization of transient problem with maximum dynamic response constraint using SOAR scheme

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Mechanical Engineering 2021年第3期16卷 593-606页

作者： Kai LONG xiaoyu YANG Nouman SAEED Ruohan TIAN Pin wen Xuan WANG State Key Laboratory for Alternate Electrical Power System with Renewable Energy Sources North China Electric Power UniversityBeijing 102206China Hubei Key Laboratory of Theory and Application of Advanced Materials Mechanics School of ScienceWuhan University of TechnologyWuhan 430070China Department of Engineering Mechanics Hefei University of TechnologyHefei 230009China

This paper proposes a novel method for the continuum topology optimization of transient vibration problem with maximum dynamic response constraint.An aggregated index in the form of an integral function is presented to cope with the maximum response constraint in the time domain.The density filter solid isotropic material with penalization method combined with threshold projection is developed.The sensitivities of the proposed index with respect to design variables are conducted.To reduce computational cost,the second-order Amoldi reduction(SOAR)scheme is employed in transient analysis.Influences of aggregate parameter,duration of loading period,interval time,and number of basis vectors in the SOAR scheme on the final designs are discussed through typical examples while unambiguous configuration can be achieved.Through comparison with the corresponding static response from the final designs,the optimized results clearly demonstrate that the transient effects cannot be ignored in structural topology optimization.

关键词： topology optimization solid isotropic material with penalization transient response aggregation function second-order Amoldi reduction

Comparison of the osteogenic capability of rat bone mesenchymal stem cells on collagen,collagen/hydroxyapatite,hydroxyapatite and biphasic calcium phosphate

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2018年第2期5卷 93-103页

作者： xiaoyu Sun wen Su Xiaomin Ma Huaiying Zhang Zhe Sun Xudong Li National Engineering Research Center for Biomaterials Sichuan UniversityChengdu 610064P.R.China

Collagen(COL),collagen/hydroxyapatite(COL/HA),HA and biphasic calcium phosphate were prepared as representative bone grafting materials with composition analogous to bone,and their structural characteristics were analyzed.The rat bone mesenchymal stem cells(BMSCs)were further seeded onto four groups of materials,and BMSCs grown in basic medium and standard osteogenic medium were set as controls of a reference model to show the basic and osteogenic behavior of cells without the intervention of materials.Cellular behaviors were characterized,including proliferation,spreading morphology and expression of osteogenesis factors.The rat BMSCs proliferated properly with time on four groups of materials as well on two groups of controls,and typical cuboidal,polygonal and extremely-elongated morphologies of cells were observed.According to the real-time polymerase chain reaction data,a higher osteogenic gene expression level was dependent upon the growing morphology but not the proliferation rate of cells,and the osteogenic differentiation capacity of cells onto four groups of materials varied in specific genes.In general,BMSCs exhibited the highest osteogenic capacity onto COL/HA,but the poorest onto HA.The growing behaviors of cells on materials were further discussed in comparison with the cases of OC and BC of the reference model.The present attempt to comparatively analyze cell experimental data with a reference model is expected to be useful for revealing the difference in the osteogenic capability of MSCs onto materials or even the bioactivity of materials.

关键词： osteogenic differentiation spreading morphology mineralization of collagen bioceramics